Methods For The Diagnosis Of Dementia And Other Neurological Disorders

  • Published: May 18, 2011
  • Earliest Priority: Feb 28 2006
  • Family: 25
  • Cited Works: 35
  • Cited by: 0
  • Cites: 3
  • Additional Info: Cited Works Published
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Abstract

The present invention is directed to a method for diagnosing a patient's Alzheimer's disease health state or change in health state, or for diagnosing Alzheimer's disease, dementia, cognitive impairment, the risk of Alzheimer's disease, the risk of Cognitive impairment, or the risk of dementia in a patient. The method comprises analyzing a blood sample from a patient by high resolution mass spectrometry to obtain accurate mass intensity data; b) comparing the accurate mass intensity data to corresponding data obtained for one or more than one reference sample to identify an increase or decrease in accurate mass intensity; and c) using said increase or decrease in accurate mass intensity to diagnose said patient's Alzheimer's disease health state or change in health state, or for diagnosing Alzheimer's disease, dementia, cognitive impairment, the risk of Alzheimer's disease, the risk of cognitive impairment, or the risk of dementia in said patient.


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