Inhibitors Of P53-mdm2 Interaction


The present invention describes the compound of general formula 1 (Formula 1) their salts or esters for the treatment of diseases that are positively influenced by the inhibition of p53-MDM2 or p53-MDMX interaction. In particular for the treatment of neoplasias, preferably for the treatment of cancer, namely breast, colorectal, prostate, kidney, lung cancers, melanoma, osteosarcoma or embryonal nephroma, among others.

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Document History
  • Publication: Jul 18, 2013
  • Application: Jan 9, 2013
    WO IB 2013050193 W
  • Priority: Jan 9, 2012
    PT PT 10608812 A

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