Biological Agents Active In Central Nervous System

Abstract

Cell-permeant fusion peptides Tat-PDZ can dose-dependently reduce the threshold for anesthesia. PDZ domain-mediated protein interactions at synapses in the central nervous system play an important role in the molecular mechanisms of anesthesia. Moreover, Tat- PDZ cell-permeant fusion peptides are delivered intracellularly into neurons in the central nervous system subsequent to intraperitoneally injection. By in vitro and in


Claims
Download PDF
Document Preview
Document History
  • Publication: Oct 30, 2008
  • Application: Apr 17, 2008
    WO US 2008/0060627 W
  • Priority: Apr 19, 2007
    US US 92532507 P
  • Priority: Apr 19, 2007
    US US 92532207 P

Download Citation


Sign in to the Lens

Feedback