The present invention relates to inhibitors of pro-MMP10 expression and/or MMP10 activity for treating or preventing PAH in SSc patients.The present invention further relates to an in vitro method for diagnosing a pulmonary arterial hypertension (PAH) in a systemic sclerosis (SSc) patient from a biological sample by measuring pro-MMP expression in said sample and comparing it to one reference value.

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Document History
  • Publication: Jun 1, 2017
  • Application: Nov 25, 2016
    WO EP 2016078908 W
  • Priority: Apr 26, 2016
    EP EP 16020154 A
  • Priority: Nov 26, 2015
    EP EP 15306882 A

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