Neutralizing Antibodies To Hiv-1 And Their Use

Abstract

Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes.


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Document History
  • Publication: Nov 3, 2015
  • Application: Sep 24, 2010
    US US 201013498125 A
  • Priority: Sep 24, 2010
    US US 201013498125 A
  • Priority: Sep 24, 2010
    US US 2010/0050295 W
  • Priority: Sep 22, 2010
    US US 38553110 P
  • Priority: Aug 27, 2010
    US US 40231410 P
  • Priority: May 20, 2010
    US US 34680810 P
  • Priority: Dec 24, 2009
    US US 29013509 P
  • Priority: Oct 16, 2009
    US US 25261309 P
  • Priority: Sep 25, 2009
    US US 24603909 P

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