Heterotricyclic Compounds As Serotonergic And/or Dopaminergic Agents And Uses Thereof

  • Published: Jul 22, 2015
  • Earliest Priority: Mar 28 2007
  • Family: 4
  • Cited Works: 42
  • Cited by: 0
  • Cites: 18
  • Additional Info: Cited Works Published
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Abstract

The present invention relates to a compound having the general Formula I: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ A-B-D €ƒ€ƒ€ƒ€ƒ€ƒFormula I or a pharmaceutically acceptable salt thereof, wherein: A is a moiety having general Formula II: B is a moiety selected from the group consisting of: whereas: a dashed line denotes a saturated or non-saturated bond; and R 1 -R 4 are each independently selected from the group consisting of hydrogen, alkyl, hydroxy, alkoxy, thiohydroxy, thioalkoxy, halide, amine, -C(=O)-NRxRy, -NRy-C(=O)Rx, -C(=O)-Rx, -C(=O)-ORx, -OC(=O)-Rx, -C(=S)-ORx, -OC(=S)-Rx, epoxide (oxirane), -S(=O) 2 -Rx, -S(=O)-Rx, -S(=O) 2 -NRxRy, -NRy-S(=O) 2 Rx, nitro, nitrile, isonitrile, thiirane, aziridine, nitroso, -NRx-NRyRw, -NRx-C(=O)ORy, -OC(=O)-NRxRy, -NRx-C(=S)ORy and -OC(=S)-NRxRy, each being substituted or non-substituted, wherein Rx, Ry and Rw are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl and aryl.


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Document History
  • Publication: Jul 22, 2015
  • Application: Sep 24, 2007
    EP EP 15150907 A
  • Priority: Sep 24, 2007
    EP EP 07827148 A
  • Priority: Mar 28, 2007
    IL IL 2007000404 W

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