Device To Expose Cells To Fluid Shear Forces And Associated Systems And Methods

Abstract

The present technology relates generally to devices to expose cells to fluid shear forces and associated systems and methods. In particular, several embodiments are directed toward devices to expose cells to fluid shear forces in order to measure changes in internal cell forces. In some embodiments, a fluidic device includes a flow unit configured to induce fluid flow through the device. The device further includes a fluid channel configured to accept a biological sample dispersed on an array of flexible structures. The flow unit can be configured to induce disturbed and/or laminar flow in the fluid channel. The device can further include optical or magnetic detection means configured to measure a degree of deflection of one or more flexible structures in the array.


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Document History
  • Publication: Sep 22, 2015
  • Application: Oct 29, 2012
    US US 201213663339 A
  • Priority: Oct 29, 2012
    US US 201213663339 A
  • Priority: Oct 4, 2012
    US US 201261709809 P
  • Priority: May 10, 2012
    US US 201261645191 P
  • Priority: Oct 27, 2011
    US US 201161552052 P

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