Divalent Metal-ion Loaded Nano-transport System Having A Dendritic Architecture Useful For Therapy

  • Published: Aug 20, 2008
  • Earliest Priority: Feb 16 2007
  • Family: 9
  • Cited Works: 4
  • Cited by: 2
  • Cites: 6
  • Additional Info: Cited Works Published
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Abstract

Described is the use of a nanocarrier having a dendritic structure which is composed of a dendritic core and at least one shell for the non-covalent encapsulation and/or transport of divalent metal-ions, preferably Cu-ions or Zn(II)-ions. Also described is a pharmaceutical composition containing such nanocarrier complexed divalent metal-ions in a non-covalent encapsulated form. Finally several therapeutic uses of such a nanocarrier divalent metal-ion complex are described, for example for slowing down ageing or for the treatment of Cu-ion transport disorders like Alzheimer's disease (AD) or Menkes disease.


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Document History
  • Publication: Aug 20, 2008
  • Application: Feb 16, 2007
    EP EP 07003315 A
  • Priority: Feb 16, 2007
    EP EP 07003315 A

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