Disease Model Incorporation Into An Artificial Immune System (ais)


The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the tissues of the immune system in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates and other materials in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system, coupled with disease models to provide a more complete representation of an immune response.

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Document History
  • Publication: Aug 10, 2010
  • Application: Mar 12, 2008
    US US 4710708 A
  • Priority: Mar 12, 2008
    US US 4710708 A
  • Priority: Jun 15, 2006
    US US 45300306 A
  • Priority: Apr 28, 2005
    US US 11623405 A
  • Priority: Jan 13, 2005
    US US 64317505 P
  • Priority: Apr 28, 2004
    US US 56584604 P

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