Nucleic Acid Respiratory Syncytial Virus Vaccines

Abstract

Vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described. Such vectors also may contain a further nucleotide sequence located adjacent to the RSV F protein encoding sequence to enhance the immunoprotective ability of the RSV F protein when expressed in vivo. Such vectors may be used to immunize a host, including a human host, by administration thereto. Such vectors also may be used to produce antibodies for detection of RSV infection in a sample.


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Document History
  • Publication: Jan 13, 2004
  • Application: Sep 13, 1999
    US US 39533699 A
  • Priority: Sep 13, 1999
    US US 39533699 A
  • Priority: Jun 7, 1995
    US US 47639795 A

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