{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"108-532-682-444-550","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"108-532-682-444-550","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10710,"type":"PATENT","title":"University of Colorado Boulder Patent Portforlio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":7179,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8227,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:\"University Colorado\" \"univ* Colorado\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4836
Search Applicants and Owners separately:\"University Colorado\" \"univ* Colorado\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4836
wherein the protein, variant or fragment has telomerase catalytic activity when complexed with a telomerase RNA, and\n
wherein a single-stranded DNA consisting of said encoding region hybridizes to a second single-stranded DNA at 5° C. to 25° C. below Tm in aqueous solution at 1 M NaCl, wherein said second DNA is exactly complementary to SEQ. ID NO:224, and Tm is the melting temperature under the same reaction conditions of double-stranded DNA having the sequence of SEQ. ID NO:224."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 1, further comprising a promoter, an enhancer, or a 3′ untranslated region."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 1, selected from a recombinant bacteriophage, a plasmid, a cosmid, a yeast expression vector, and a viral expression vector."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 1, selected from a mammalian virus expression vector, an SV40 virus expression vector, an EBV expression vector, an Autographa californica nuclear polyhedrosis virus expression vector, an adenovirus expression vector, a retrovirus expression vector, a herpes virus expression vector, and a vaccinia virus expression vector."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 2, wherein the promoter is a constitutive promoter."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 2, wherein the promoter is an inducible promoter."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 2, wherein the promoter is selected from an alpha factor promoter, an alcohol oxidase promoter, a PGH promoter, a 35S promoter of CaMV, a 19S promoter at CaMV, a lacZ promoter, a ptrp-lac hybrid promoter, a polyhedrin promoter, a heat shock promoter, a RUBISCO promoter, and a storage protein gene promoter."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 1, further comprising a viral origin of replication."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 1, further comprising a selectable marker gene."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 9, wherein the selectable marker gene is selected from herpes simplex virus thymidine kinase, adenine phosphoribosyltransferase, dhfr, npt, ala, pat, trpB, hisD, anthocyanin, β-glucuronidase, and luciferase."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["A host cell comprising the expression vector of claim 1."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["A host cell comprising the expression vector of claim 2."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["A host cell comprising the expression vector of claim 3."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["A host cell comprising the expression vector of claim 4."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["An expression vector containing a polynucleotide that comprises an encoding region for a polypeptide containing SEQ. ID NO:225, or fragment thereof that has telomerase catalytic activity when complexed with a telomerase RNA."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 15, which is an adenovirus expression vector, a retrovirus expression vector, a herpes virus expression vector, or a vaccinia virus expression vector."],"number":16,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 15, further comprising a constitutive or inducible promoter operably linked to the encoding region."],"number":17,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 15, which causes expression at telomerase reverse transcriptase in mammalian cells."],"number":18,"annotation":false,"claim":true,"title":false},{"lines":["The expression vector of claim 15, in a composition that comprises a pharmaceutically acceptable carrier."],"number":19,"annotation":false,"claim":true,"title":false},{"lines":["A host cell comprising the expression vector of claim 15."],"number":20,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}