{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"101-217-531-072-652","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"101-217-531-072-652"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":6802,"type":"PATENT","title":"Univ Queensland Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8841,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8194,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Copied from Raj's collection ' Univ Queensland'
.......................
Annie's search
Search applicants = 'Univ* AND Queensl* AND NOT Technology', 'Univ* AND Queensl* AND NOT STATE', ' Univ* AND Queensl* AND NOT STATE AND NOT TECHNOLOGY'.
notes: When search ' Univ* AND Queens* AND NOT Technology' only, the results came out with many patents that belong to Queensland State Government and Other universities. Hence, re set the search terms as' ' Univ* AND Queensl* AND NOT STATE AND NOT TECHNOLOGY'.
Search Owners(US) = ' Univ* AND Queensl* AND NOT STATE AND NOT TECHNOLOGY'
Add to collection
Select more for logical variants
Select all the patents in the collection and expand by simple families
Add to collection
Total patents = 8993
Search Applicants and Owners separately: \"Univ* Queensland\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4376
\n","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3943,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[],"sharedType":"PUBLISHED","hasLinkedSavedQueries":false,"savedQueries":[],"created":"2016-06-13T09:23:24Z","updated":"2017-08-08T02:15:44Z","lastEventDate":"2017-08-08T02:15:44Z"},{"id":22856,"type":"PATENT","title":"Citing NIH publications","description":"Patent documents citing scholarly work of NIH","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":151649,"tags":[],"user":{"id":233682368,"username":"tech","firstName":"The Lens","lastName":"Team","created":"2017-08-06T20:11:49.000Z","displayName":"The Lens 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filled by agents who have Queensland as address","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":7492,"tags":[],"user":{"id":369423973,"username":"Lens Reports","firstName":"Lens","lastName":"Reports","created":"2020-09-16T23:25:18.000Z","displayName":"Lens Reports","profilePictureKey":"lens/avatar/00bf8c3d-2675-48ad-9d6e-5cf58c675620","avatar":{"id":1069,"key":"lens/avatar/00bf8c3d-2675-48ad-9d6e-5cf58c675620"},"preferences":"{\"beta\":true,\"usage\":\"public\"}","accountType":"PERSONAL","isOauthOnly":false},"notes":[],"sharedType":"PUBLISHED","hasLinkedSavedQueries":true,"savedQueries":[],"created":"2023-03-06T05:04:19Z","updated":"2024-03-28T02:46:08Z","lastEventDate":"2024-03-28T02:46:08Z"}],"notes":[],"inventorships":[],"privateCollections":[],"publicCollections":[{"id":6802,"type":"PATENT","title":"Univ Queensland Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8841,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8194,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"Copied from Raj's collection ' Univ Queensland'
.......................
Annie's search
Search applicants = 'Univ* AND Queensl* AND NOT Technology', 'Univ* AND Queensl* AND NOT STATE', ' Univ* AND Queensl* AND NOT STATE AND NOT TECHNOLOGY'.
notes: When search ' Univ* AND Queens* AND NOT Technology' only, the results came out with many patents that belong to Queensland State Government and Other universities. Hence, re set the search terms as' ' Univ* AND Queensl* AND NOT STATE AND NOT TECHNOLOGY'.
Search Owners(US) = ' Univ* AND Queensl* AND NOT STATE AND NOT TECHNOLOGY'
Add to collection
Select more for logical variants
Select all the patents in the collection and expand by simple families
Add to collection
Total patents = 8993
Search Applicants and Owners separately: \"Univ* Queensland\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4376
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(1999).","npl_type":"a","external_id":["10053134","10.1006/jmre.1998.1673"],"record_lens_id":"058-321-484-494-600","lens_id":["102-503-446-363-846","058-321-484-494-600","102-905-441-066-852"],"sequence":5,"category":[],"us_category":[],"cited_phase":"APP","rel_claims":[]}},{"npl":{"num":6,"text":"DK Jones, MA Horsfield, A Simmons, \"Optimal Strategies for Measuring Diffusion in Anisotropic Systems by Magnetic Resonance Imaging\", Magnetic Resonance in Medicine, 42:515-525 (1999).","npl_type":"a","external_id":["10.1002/(sici)1522-2594(199909)42:3<515::aid-mrm14>3.3.co;2-h","10467296","10.1002/(sici)1522-2594(199909)42:3<515::aid-mrm14>3.0.co;2-q"],"record_lens_id":"053-266-559-130-879","lens_id":["091-526-457-537-316","053-266-559-130-879","103-638-099-604-91X","044-123-515-221-483","044-319-791-281-487"],"sequence":6,"category":[],"us_category":[],"cited_phase":"APP","rel_claims":[]}},{"npl":{"num":7,"text":"Stejskal et al., \"Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient\", Journal of Chemical Physics, 42(1): 288-292 (1965).","npl_type":"a","external_id":["10.1063/1.1695690"],"record_lens_id":"142-382-489-379-648","lens_id":["165-852-702-700-583","142-382-489-379-648"],"sequence":7,"category":[],"us_category":[],"cited_phase":"APP","rel_claims":[]}},{"npl":{"num":8,"text":"Y. Bito, S. Hirata, E. Yamamoto, \"Optimal gradient factors for ADC measurements\", Proceedings of the 3a) obtaining a spin echo signal in a readout time window by excitation of a nuclear resonance signal using a first radio-frequency pulse and by refocusing that signal using at least one second radio-frequency pulse and a third radio-frequency pulse;
b) applying imaging gradient fields prior to a first restoring pulse to the spatially encode image in slice, read and phase directions;
c) applying additional, after said first refocusing pulse, gradient fields of a specfic direction and amplitude through activation of gradient pulses between each of said radio-frequency pulses and prior to said readout window, said gradient pulses having a polarity which is alternated between successive gradient pulses, a totality of said gradient pulses having a gradient time integral of zero between a time of said excitation and the center of k x or k-space, with at least two of said gradient pulses having differing gradient time integrals;
d) changing said gradient direction; and
e) repeating steps a) to c) to evenly distribute the additional gradient direction vectors over a sphere."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 , further comprising adjustment of time locations of said radio-frequency pulses, said readout time window and said gradient fields to maximize a diffusion parameter related signal to noise ratio and to minimize eddy current field distortion at the center of k x or k-space."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 2 , wherein said time locations are iteratively and systematically varied to obtain a relative maximum in said signal to noise ratio and a relative minimum in said eddy current field distortion."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed as a function of echo times."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 4 , wherein said time locations are analyzed as a function of gradient field durations dependent upon echo times."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 5 , wherein said time locations are analyzed as a function of an eddy current decay time."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed as a function of a number of measurements."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed as a function of a gradient time integral."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed as a function of the diffusivity of the sample under measurement."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed as a function of transverse relaxation time."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed using the following formula: σ D = σ e 2 TE T 2 ( N H + ( N - N H ) · e 2 b max D S o 2 b max 2 N H ( N - N H ) ) wherein σ D is an error in a diffusion measurement, b max a gradient time integral of a diffusion gradient, N a given number of measurements, N H a subset of measurements acquired at b max , S 0 an initial signal amplitude of moving spins in a diffusion weighted sequence, D a diffusivity, TE an echo time, T 2 a transverse relaxation rate, and σ 2 a variance of a noise portion of a measured signal."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 , wherein said time locations are analyzed using the following formula H ( t )≅ e −λ i (tD1+tD2+tD3+tD4+2t180+t s) −e −λ i (tD2+tD3+tD4+2t180+t s) −e −λ i (tD2+tD3+tD4+t180+t s) + 2 e −λ i (tD3+tD4+t180+t s) −e −λ i (tD4+t180+t s) −e −λ i (tD4+t s) +e −λ i (t s) wherein H(t) is a magnetic field due to eddy currents, λ i a decay rate of eddy currents triggered by a rise and fall of gradients, i an index of a number of different decay rates generated for each gradient switching point, t Dj a duration of a jth diffusion gradient, t 180 a time of an RF refocusing pulse, and t s a delay before a center of an echo or a center of K-space."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 , further comprising selecting said gradient field strengths in steps c) and e) to maximize diffusion imaging sensitivity."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 , wherein steps c), d), and e) comprise simultaneous application of three gradients in three orthogonal spatial directions and changing relative field strengths of said three gradients between successive iterations of step e)."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 14 , wherein said three gradients are expressed in Cartesian or radial coordinates."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 , wherein step c) comprises the steps of:
c1) activating a gradient pulse of a first polarity between said first radio-frequency pulse and said second radio-frequency pulse;
c2) activating two gradient pulses of differing polarity between said second radio-frequency pulse and said third radio-frequency pulse, beginning with a polarity which is opposite to said first polarity; and
c3) activating another gradient pulse between said third radio-frequency pulse and said readout window."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 , further comprising application of said slice selection gradient during a time duration of said radio-frequency pulses."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 , wherein step b) comprises the steps of:
b1) spatially encoding a spin echo signal by activating a phase-encoding gradient prior to said readout; and
b2) activating a readout gradient during said readout time window, or:
b3) activating a series of oscillating readout gradients during said readout time window, incorporating phase encoding between each readout gradient."],"number":18,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}