1-(arylmethyl)quinazoline-2,4(1h,3h)-diones As Parp Inhibitors And The Use Thereof

Abstract

Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity.


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Document History
  • Publication: Mar 27, 2018
  • Application: Feb 12, 2016
    US US 201615042366 A
  • Priority: Feb 12, 2016
    US US 201615042366 A
  • Priority: Sep 23, 2013
    US US 201314006722 A
  • Priority: Mar 31, 2012
    CN CN 2012073362 W
  • Priority: Jul 11, 2011
    CN CN 2011077034 W
  • Priority: Apr 1, 2011
    CN CN 201110082475 A

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