Method For Topical Treatment Of Eye Disease And Composition And Device For Said Treatment

Abstract

A method for the prevention or treatment of an eye disease, which includes topically applying to a patient in need of the treatment an aqueous ophthalmic composition which includes N-acetylcarnosine, a N-acetylcarnosine derivative or a pharmacologically acceptable salt of N-acetylcarnosine, in combination with an amount of a cellulose compound or a pharmacologically acceptable salt which is effective to increase intraocular absorption of N-acetylcarnosine or L-carnosine or a derivative of L-carnosine, such as anserine or balenine, in the aqueous humor. A hydrophilic hydrogel contact lens and an ocular polymer insert for topical application of an ophthalmic composition to the eyes of a patient is also disclosed, with the lens or insert containing N-acetylcarnosine, a N-acetylcarnosine derivative or a pharmacologically acceptable salt of N-acetylcarnosine.


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Document History
  • Publication: Sep 14, 2010
  • Application: Dec 12, 2003
    US US 48072403 A
  • Priority: Dec 12, 2003
    US US 48072403 A
  • Priority: Sep 29, 2003
    IB IB 0304259 W
  • Priority: Sep 30, 2002
    US US 41435702 P

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