Chimeric Alphavirus Replicon Particles

Abstract

Chimeric alphaviruses and alphavirus replicon particles are provided including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed.


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Document History
  • Publication: May 12, 2009
  • Application: Apr 11, 2002
    US US 12310102 A
  • Priority: Apr 11, 2002
    US US 12310102 A
  • Priority: May 31, 2001
    US US 29545101 P

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