Method For Treating Cartilage Disorders

Abstract

The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor.


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Document History
  • Publication: Sep 9, 2008
  • Application: Oct 16, 2002
    US US 27186902 A
  • Priority: Oct 16, 2002
    US US 27186902 A
  • Priority: May 16, 2001
    US US 85893501 A
  • Priority: Nov 15, 2000
    US US 24898500 P
  • Priority: May 16, 2000
    US US 20449000 P
  • Priority: Jan 5, 2000
    US US 47792300 A
  • Priority: Jan 5, 2000
    US US 47792400 A
  • Priority: Dec 9, 1999
    US US 17026199 P
  • Priority: Jun 22, 1999
    US US 33722799 A
  • Priority: Jan 6, 1999
    US US 11501099 P
  • Priority: Mar 31, 1998
    US US 5288898 A
  • Priority: Apr 4, 1997
    US US 82585297 A

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