Hellebrin Derivatives


The present invention relates to new cardiotonic steroids and their use in the treatment of cancer, in particular to compounds of Formula (I), stereoisomers, tautomers, racemates, prodrugs, metabolites, or a pharmaceutically acceptable salts, hydrates, or solvates thereof, wherein R1, R2, R3, R4, and R5 have the same meaning as that defined in the claims. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds in the treatment and prophylaxis of cancer.


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