Treating Neurological Disorders Using Selective Antagonists Of Persistent Sodium Current


The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.

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Document History
  • Publication: Jun 1, 2010
  • Application: Jan 5, 2006
    US US 32626406 A
  • Priority: Jan 5, 2006
    US US 32626406 A
  • Priority: Aug 27, 2004
    US US 92894904 A
  • Priority: Aug 29, 2003
    US US 49890203 P

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