Methods For The Diagnosis Of Peripheral Nerve Damage

Abstract

Methods of diagnosing peripheral nerve damage, including diagnosing and monitoring chronic back and cervical pain are disclosed. The methods involve subjecting a body fluid sample from a patient suspected of having chronic lumbar or cervical pain and peripheral nerve damage to two-dimensional electrophoresis or an immunoassay and measuring relative amounts of protein or proteins which increase or decrease in concentration as compared to a standard control. A preferred method employs an Apo-E variant as a marker of peripheral nerve damage. Also disclosed are kits for use with the diagnostic methods.


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Document History
  • Publication: Dec 1, 1998
  • Application: Jun 7, 1995
    US US 47534595 A
  • Priority: Jun 7, 1995
    US US 47534595 A
  • Priority: May 16, 1994
    US US 24298094 A
  • Priority: Dec 1, 1992
    US US 98344392 A
  • Priority: Nov 15, 1991
    US US 9108552 W
  • Priority: Nov 30, 1990
    US US 62010490 A

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