Small Molecule Inhibitors Of Trpa1

  • Published: Apr 12, 2017
  • Earliest Priority: May 12 2011
  • Family: 11
  • Cited Works: 42
  • Cited by: 0
  • Cites: 9
  • Additional Info: Cited Works
Full-text?

The full document isn't yet available to us from the patent office.

Abstract

The present invention relates to the use of compounds which are capable of attenuating skin irritation when they are applied to the skin. Skin irritation can be caused, enter alia, by ingredients of cosmetic or pharmaceutical compositions and/or environmental irritants. In particular, the present invention relates to compounds having the property of antagonizing the activation of the transient receptor potential (TRP) ankyrin 1 (TRPA1) ion channel and the use of said compounds as soothing agents. Such compounds can be used in many fields, particularly in personal-care products, cosmetics, textile and packaging products, pharmaceutical compositions, medical devices, and foodstuffs. The present invention further relates to products and/or pharmaceutical compositions containing said compounds. The present invention also relates to the use of the compounds described herein for the modulation of the taste of a food product.


Claims

Information currently unavailable.

CPC Classifications

Download Citation


Sign in to the Lens

Feedback