Pulmonary Delivery Of Spherical Insulin Microparticles

  • Published: Oct 30, 2008
  • Earliest Priority: Apr 17 2007
  • Family: 9
  • Cited Works: 0
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  • Additional Info: Full text Published

Compositions of spherical insulin particles having improved pulmonary application potentials and methods of forming and using these compositions are disclosed in the present application. In one clinical trial with 30 healthy male human subjects, no coughing was observed upon a single pulmonary administration of the spherical insulin particles at an insulin dose of 6.5 mg, nor during the 10-hour post dosing period.


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