Naphthyridines As Integrin Antagonists

Abstract

The invention relates to compounds of Formula (I): wherein R1, R2 and R3 are as defined in the description and claims, or pharmaceutically acceptable salts thereof having ανβ6 integrin antagonist activity. The invention also relates to pharmaceutical compositions including a compound of formula (I) or a pharmaceutically acceptable salt thereof, and to the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in therapy, including in the treatment of a disease or condition for which an ανβ6 integrin antagonist is indicated, and in particular the treatment of idiopathic pulmonary fibrosis.


Claims

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