Highly Sensitive Rapid Isothermal Method For The Detection Of Methylation Patterns

Abstract

The current invention refers to a method for detecting methylation patterns of a nucleotide sequence by an improvement of the LAMP (Loop-mediated Isothermal Amplification) amplification method, related kits and set of primers. As non limitative embodiment the invention refers to the simplex or multiplex detection of methylation patters in the CDKN2A, GATA5 and DAPK1 human genes.


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Document History
  • Publication: Feb 10, 2011
  • Application: Jul 29, 2010
    WO EP 2010061072 W
  • Priority: Aug 5, 2009
    EP EP 09167294 A

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