{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"087-614-114-102-877","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"087-614-114-102-877","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":12123,"type":"PATENT","title":"Rush University Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":496,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8628,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:Rush Univ*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 496
Search Applicants and Owners separately:Rush Univ*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 496
a covalent adduct of an H2SO4-modified mandelic acid and a nitric oxide donor,\n
the nitric oxide donor consisting of a nitric oxide donor moiety and a spacer;\n
the nitric oxide donor being covalently bonded through the spacer to a carbonyl carbon atom derived from a carboxyl of the H2SO4-modified mandelic acid wherein NO is released from the anti-microbial agent during use."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 1, wherein the NO-donor is selected from the group consisting of nitrate esters, furoxans, ketoximes, S-nitrosothiols, nitrosohydrazines, and hydroxylamides."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 1, wherein the NO-donor is a nitrate ester."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 1, wherein the antimicrobial agent is contained in an inert carrier."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 3, wherein the antimicrobial agent is contained in an inert carrier."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 4, wherein the antimicrobial agent is at a concentration greater than about 0.2 mg/g."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 5, wherein the antimicrobial agent is at a concentration greater than about 0.2 mg/g."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 4, wherein the antimicrobial agent is at a concentration of about 10 to 100 mg/g."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 5, wherein the antimicrobial agent is at a concentration of about 10 to 100 mg/g."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent as defined in claim 1, wherein the H2SO4-modified mandelic acid is a fractionated H2SO4-modified mandelic acid having a narrower molecular weight range and a higher biological activity relative to the H2SO4-modified mandelic acid without fractionation."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent of claim 1, wherein the covalent adduct of the H2SO4-modified mandelic acid and the nitric oxide donor is a compound having a structure:\n
wherein n is an average of 10 and the nitric oxide donor comprises a nitrate ester moiety; and\n
R at each monomer is independently H, —(CH2)m—O—NO2 wherein m is 2-6 or 1,3-nitrooxyphenyl."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent of claim 11 wherein the the R′s are each independently H or —(CH2)3—O—NO2."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent of claim 11 wherein about 7% of the R′s are (CH2)3—O—NO2 and the remaining about 93% of the R′s are H."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The anti-microbial agent of claim 11 wherein about 23% of the R′s are (CH2)3—O—NO2 and the remaining about 77% of the R′s are H."],"number":14,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}