Gene Polymorphisms As Sex-specific Predictors In Cancer Therapy


The invention provides compositions and methods for determining the likelihood of gender-specific successful treatment with 5-FU/oxaliplatin or an equivalent of each thereof. The methods comprise determining the genomic polymorphism present in a predetermined region of a gene of interest and correlating the polymorphism to the predictive response. Patients identified as responsive are then treated with the appropriate therapy.

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Document History
  • Publication: Jul 24, 2008
  • Application: Jan 18, 2008
    WO US 2008/0051527 W
  • Priority: Jan 17, 2008
    US US 2008/0000709 W
  • Priority: Jan 18, 2007
    US US 88560507 P

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