WO 2009/047043 A1 - Co-crystals Of Pyrimethanil And Dithianon - The Lens

Co-crystals Of Pyrimethanil And Dithianon

Published: Apr 16, 2009
Earliest Priority: Sep 07 2007
Family: 30
Cited Works: 0
Cited by: 10
Cites: 1
Additional Info: Full text

Abstract

The present invention relates to co-crystals of pyrimethanil and dithianon, which, in a X-ray powder diffractogram at 25°C show at least three of the following reflexes: 2? = 7.46 ± 0.20, 2? = 9.98 ± 0.20, 2? = 13.28 ± 0.20, 2? = 23.09 ± 0.2, 0.2? = 24.38 ± 0.20, 2? = 27.01 ± 0.20 a process for their preparation and their use for the preparation of compositions for crop protection.

Claims

Co-crystals of pyrimethanil and dithianon, which, in a X-ray powder diffractogram at 25°C, show at least three of the following reflexes:
2Θ = 7.46 ± 0.20 2Θ = 9.98 ± 0.20 2Θ = 13.28 ± 0.20 2Θ = 23.09 ± 0.20 2Θ = 24.38 ± 0.20
2Θ = 27.01 ± 0.20
Co-crystals according to claim 1 having a melting point in the range of 165 to 175°.
A process for the preparation of the co-crystals according to claim 1 , comprising the following steps: i) dissolving equimolar amounts of pyrimethanil and dithianon in a polar organic solvent, ii) evaporating the solvent to form the co-crystals.
A process for the preparation of the co-crystals according to claim 1 , comprising the following steps: i) dry-mixing equimolar amounts of pyrimethanil and dithanion to form a premix, ii) dry-grinding the premix to form the co-crystals.
A process for the preparation of the co-crystals according to claim 1 , comprising the following steps: i) mixing equimolar amounts of pyrimethanil and dithianon with a liquid carrier to form a premix, ii) grinding the premix to form the co-crystals on the carrier, iii) separating the co-crystals from the carrier.
A composition for crop protection, comprising co-crystals according to claim 1 and carriers and/or auxiliaries.
The composition of claim 6 in the form of an aqueous or based suspension concentrate.
The composition of claim 6 in the form of an aqueous or vegetable or mineral oil based suspension concentrate.
A process for the preparation of an aqueous suspension concentrate, comprising the following steps: i) adding pyrimethanil into water which contains one or more dispersing agents and optionally other auxiliaries to form a premix A, ii) adding dithianon into water which contains one or more dispersing agents and optionally other auxiliaries to form a premix B, iii) mixing the premixes A and B together under stirring at a temparature from
200C to 1500C to form a dark green suspension of co-crystals according claim
1 , iv) milling the so obtained suspension to a particle size distribution 80 % < 2 μm.
A process for the preparation of an aqueous suspension concentrate, comprising the following steps: i) adding pyrimethanil into water which contains one or more dispersing agents and optionally other auxiliaries to form a premix A, ii) mixing the premix A with dithianon under stirring at a temparature from 200C to
150°C to form a dark green suspension of co-crystals according claim 1 , iii) milling the so obtained suspension to a particle size distribution 80 % < 2 μm.
1 1. A process for the preparation of an aqueous suspension concentrate, comprising the following steps: i) adding dithianon into water which contains one or more dispersing agents and optionally other auxiliaries to form a premix B, ii) mixing the premix B with pyrimethanil under stirring at a temparature from 200C to 1500C to form a dark green suspension of co-crystals according claim
1 , iii) milling the so obtained suspension to a particle size distribution 80 % < 2 μm.
A process according to claim 9, wherein the temperature in step iii) is from 40 to 60°C.
A process according to claim 9, wherein the temperature in step iv) is from 20 to 30°C.
An aqueous suspension concentrate, comprising co-crystals of pyrimethanil and dithianon according to claim 1 , water and auxiliaries.
The use of the composition according to claim 6 for controlling phytopathogenic fungi.