Methods For Identifying Inhibitors Of Neuronal Degeneration

Abstract

Disclosed herein are methods for identifying inhibitors of neuronal degeneration, and their use in the treatment of neurodegenerative disorders. In particular methods methods are disclosed for identifying inhibitors of neuronal degeneration or cell death by taking advantage of the involvement of presenilin (PS) and Par-4 in NF-kappaB activation.


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Document History
  • Publication: Mar 28, 2006
  • Application: Apr 14, 2003
    US US 41742203 A
  • Priority: Apr 14, 2003
    US US 41742203 A
  • Priority: Jan 4, 2001
    US US 75494901 A
  • Priority: Jan 10, 2000
    US US 17520000 P

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