Patents
EP 2077274 A1

Synthetic Analogs Of Human Beta-defensins Having Antimicrobial, Antiviral And Chemotactic Activity

  • Published: Jul 8, 2009
  • Earliest Priority: Jan 02 2008
  • Family: 3
  • Cited Works: 46
  • Cited by: 3
  • Cites: 1
  • Sequences: 20
  • Additional Info: Cited Works
Patent Application
EP 2077274 A1
072-764-609-092-77X
Data obtained from: EMBL-EBI Pat
20 sequences found in this patent (in total)

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Download sequences in fasta format: 20 peptides

Displaying 1 - 10 of 20 sequences

SEQ ID NO
Length
Sequence Type
Locations
Declared organism
Determined organism
Occurrence
Tools
SEQ ID NO
1
Length
36
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:4885181
      NP_005209
      1 of 14 hits reported for Homo sapiens.
    • Hit length
      68 aa
    • E Value
      6.01E-13
    • BLAST Score
      78.2 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_005209
      52.94% cov
    • Alignment Length
      36 aa
    • CIGAR string
      36M mismatches: 0 - insertions: 0 - deletions: 0
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:152060597
      P60023
    • Hit length
      68 aa
    • E Value
      8.33E-12
    • BLAST Score
      74.3 bits
    • Similarity
      97.22%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      P60023
      52.94% cov
    • Alignment Length
      36 aa
  • Gorilla gorilla gorilla

    Gorilla gorilla gorilla

    • Public DB hit
      GI:61211666
      Q95M68
    • Hit length
      68 aa
    • E Value
      9.36E-12
    • BLAST Score
      74.3 bits
    • Similarity
      97.22%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      Q95M68
      52.94% cov
    • Alignment Length
      36 aa
  • Nomascus leucogenys

    Nomascus leucogenys

    • Public DB hit
      GI:332244599
      XP_003271461
    • Hit length
      68 aa
    • E Value
      3.27E-11
    • BLAST Score
      72.4 bits
    • Similarity
      97.22%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_003271461
      52.94% cov
    • Alignment Length
      36 aa
  • Trachypithecus obscurus

    Trachypithecus obscurus

    • Public DB hit
      GI:61211581
      Q7JGL9
    • Hit length
      68 aa
    • E Value
      3.8E-11
    • BLAST Score
      72.4 bits
    • Similarity
      94.44%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      Q7JGL9
      52.94% cov
    • Alignment Length
      36 aa
  • Cercopithecus preussi

    Cercopithecus preussi

    • Public DB hit
      GI:61211580
      Q7JGL8
    • Hit length
      68 aa
    • E Value
      4.24E-11
    • BLAST Score
      72 bits
    • Similarity
      94.44%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      Q7JGL8
      52.94% cov
    • Alignment Length
      36 aa
  • Pongo abelii

    Pongo abelii

    • Public DB hit
      GI:297682219
      XP_002818824
    • Hit length
      68 aa
    • E Value
      4.61E-11
    • BLAST Score
      72 bits
    • Similarity
      94.44%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_002818824
      52.94% cov
    • Alignment Length
      36 aa
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:74136275
      NP_001028029
    • Hit length
      68 aa
    • E Value
      7.17E-11
    • BLAST Score
      71.2 bits
    • Similarity
      94.44%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_001028029
      52.94% cov
    • Alignment Length
      36 aa
Occurrence
559 times in PatSeqDB
Tools
SEQ ID NO
2
Length
45
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
  • Papio anubis

    Papio anubis

    • Public DB hit
      GI:31071997
      DAA01350
    • Hit length
      67 aa
    • E Value
      8.16E-17
    • BLAST Score
      90.9 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      DAA01350
      67.16% cov
    • Alignment Length
      45 aa
    • CIGAR string
      45M mismatches: 0 - insertions: 0 - deletions: 0
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:8923890
      NP_061131
      1 of 4 hits reported for Homo sapiens.
    • Hit length
      67 aa
    • E Value
      9.02E-17
    • BLAST Score
      90.9 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_061131
      67.16% cov
    • Alignment Length
      45 aa
    • CIGAR string
      45M mismatches: 0 - insertions: 0 - deletions: 0
  • Gorilla gorilla gorilla

    Gorilla gorilla gorilla

    • Public DB hit
      GI:152112316
      A4H1Z9
    • Hit length
      67 aa
    • E Value
      9.64E-17
    • BLAST Score
      90.9 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      A4H1Z9
      67.16% cov
    • Alignment Length
      45 aa
    • CIGAR string
      45M mismatches: 0 - insertions: 0 - deletions: 0
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:296221581
      XP_002756803
    • Hit length
      77 aa
    • E Value
      1.63E-16
    • BLAST Score
      90.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      XP_002756803
      58.44% cov
    • Alignment Length
      45 aa
  • Pongo pygmaeus

    Pongo pygmaeus

    • Public DB hit
      GI:57019016
      AAW32911
    • Hit length
      47 aa
    • E Value
      2.8E-16
    • BLAST Score
      89.4 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      AAW32911
      95.74% cov
    • Alignment Length
      45 aa
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:193211435
      NP_001123222
      1 of 4 hits reported for Pan troglodytes.
    • Hit length
      67 aa
    • E Value
      4.36E-16
    • BLAST Score
      88.6 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_001123222
      67.16% cov
    • Alignment Length
      45 aa
  • Canis lupus familiaris

    Canis lupus familiaris

    • Public DB hit
      GI:194018734
      NP_001123452
    • Hit length
      67 aa
    • E Value
      1.09E-13
    • BLAST Score
      80.5 bits
    • Similarity
      95.56%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_001123452
      67.16% cov
    • Alignment Length
      45 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:301789141
      XP_002929984
      1 of 2 hits reported for Ailuropoda melanoleuca.
    • Hit length
      67 aa
    • E Value
      5.56E-13
    • BLAST Score
      78.2 bits
    • Similarity
      97.78%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      XP_002929984
      67.16% cov
    • Alignment Length
      45 aa
  • Chinchilla lanigera

    Chinchilla lanigera

    • Public DB hit
      GI:48427992
      P83943
    • Hit length
      67 aa
    • E Value
      9.82E-12
    • BLAST Score
      74.3 bits
    • Similarity
      91.11%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      P83943
      67.16% cov
    • Alignment Length
      45 aa
  • Bos taurus

    Bos taurus

    • Public DB hit
      GI:297468005
      XP_002705534
    • Hit length
      224 aa
    • E Value
      2.88E-11
    • BLAST Score
      72.8 bits
    • Similarity
      90.91%
    • Coverage
      97.78%
    • Alignment (schematic)

      SEQ ID NO 2
      97.78% cov
      XP_002705534
      19.64% cov
    • Alignment Length
      44 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:47523940
      NP_999609
    • Hit length
      67 aa
    • E Value
      2.93E-11
    • BLAST Score
      72.8 bits
    • Similarity
      88.64%
    • Coverage
      97.78%
    • Alignment (schematic)

      SEQ ID NO 2
      97.78% cov
      NP_999609
      65.67% cov
    • Alignment Length
      44 aa
Occurrence
134 times in PatSeqDB
Tools
SEQ ID NO
3
Length
39
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
4
Length
42
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
5
Length
42
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
6
Length
39
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
  • Papio anubis

    Papio anubis

    • Public DB hit
      GI:31071997
      DAA01350
    • Hit length
      67 aa
    • E Value
      4.2E-13
    • BLAST Score
      78.6 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      DAA01350
      58.21% cov
    • Alignment Length
      39 aa
    • CIGAR string
      39M mismatches: 0 - insertions: 0 - deletions: 0
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:8923890
      NP_061131
      1 of 4 hits reported for Homo sapiens.
    • Hit length
      67 aa
    • E Value
      4.27E-13
    • BLAST Score
      78.6 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      NP_061131
      58.21% cov
    • Alignment Length
      39 aa
    • CIGAR string
      39M mismatches: 0 - insertions: 0 - deletions: 0
  • Gorilla gorilla gorilla

    Gorilla gorilla gorilla

    • Public DB hit
      GI:152112316
      A4H1Z9
    • Hit length
      67 aa
    • E Value
      4.3E-13
    • BLAST Score
      78.6 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      A4H1Z9
      58.21% cov
    • Alignment Length
      39 aa
    • CIGAR string
      39M mismatches: 0 - insertions: 0 - deletions: 0
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:296221581
      XP_002756803
    • Hit length
      77 aa
    • E Value
      7.72E-13
    • BLAST Score
      77.8 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      XP_002756803
      50.65% cov
    • Alignment Length
      39 aa
  • Pongo pygmaeus

    Pongo pygmaeus

    • Public DB hit
      GI:57019016
      AAW32911
    • Hit length
      47 aa
    • E Value
      1.31E-12
    • BLAST Score
      77 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      AAW32911
      82.98% cov
    • Alignment Length
      39 aa
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:193211435
      NP_001123222
      1 of 4 hits reported for Pan troglodytes.
    • Hit length
      67 aa
    • E Value
      1.82E-12
    • BLAST Score
      76.6 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      NP_001123222
      58.21% cov
    • Alignment Length
      39 aa
  • Canis lupus familiaris

    Canis lupus familiaris

    • Public DB hit
      GI:194018734
      NP_001123452
    • Hit length
      67 aa
    • E Value
      4.38E-10
    • BLAST Score
      68.6 bits
    • Similarity
      94.87%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      NP_001123452
      58.21% cov
    • Alignment Length
      39 aa
  • Bos taurus

    Bos taurus

    • Public DB hit
      GI:297468142
      XP_002705694
      1 of 3 hits reported for Bos taurus.
    • Hit length
      152 aa
    • E Value
      1.57E-9
    • BLAST Score
      67 bits
    • Similarity
      92.31%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      XP_002705694
      25.66% cov
    • Alignment Length
      39 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:301789141
      XP_002929984
      1 of 2 hits reported for Ailuropoda melanoleuca.
    • Hit length
      67 aa
    • E Value
      2.32E-9
    • BLAST Score
      66.2 bits
    • Similarity
      97.44%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      XP_002929984
      58.21% cov
    • Alignment Length
      39 aa
Occurrence
6 times in PatSeqDB
Tools
SEQ ID NO
7
Length
36
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
8
Length
45
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
9
Length
39
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools
SEQ ID NO
10
Length
42
Sequence Type
peptide
Locations
Undetermined
Declared organism
Homo sapiens
Determined organism
Occurrence
2 times in PatSeqDB
Tools

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