Human Asparaginase Lacking Glutaminase Activity

Abstract

The invention relates to a human asparaginase comprising an amino acid sequence that is at least 90% identical to the amino acid sequence depicted in Figure, for use as a medicament. Said asparaginase was found to lack intrinsic glutaminase activity. The invention further relates to a membraneous particle comprising said asparaginase, and to a pharmaceutical composition comprising said asparaginase and a pharmaceutically acceptable excipient.


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Document History
  • Publication: Mar 22, 2018
  • Application: Sep 19, 2017
    WO EP 2017073635 W
  • Priority: Jul 3, 2017
    EP EP 17179304 A
  • Priority: Sep 19, 2016
    EP EP 16189525 A

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