{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"067-185-447-567-869","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"067-185-447-567-869"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8877,"type":"PATENT","title":"New York Univ Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":15466,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8211,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners seperately = \"New York Univ\", \"New York University NOT \"state\" NOT \"city\" \", \"Univ New York\", \"NYU\".
Search Applicants and Owners separately: stony brook Uni*; stony brook university. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 13
Search Applicants and Owners seperately = \"New York Univ\", \"New York University NOT \"state\" NOT \"city\" \", \"Univ New York\", \"NYU\".
Search Applicants and Owners separately: stony brook Uni*; stony brook university. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 13
a) obtaining the nucleotide sequence encoding the nucleoprotein (NP) of an influenza virus and the nucleotide sequence encoding a polymerase protein of an influenza virus;\n
b) rearranging the codons of the nucleotide sequences to obtain mutated nucleotide sequences that\n
i) encode the same amino acid sequences as the unrearranged nucleotide sequences, and\n
ii) have a reduced codon pair bias compared to the unrearranged nucleotide sequence; and\n
c) substituting all or part of the mutated nucleotide sequences into the unrearranged nucleotides of the influenza virus genome."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, which further comprises obtaining the nucleotide sequence encoding a virion protein of an influenza virus;\n
b) rearranging the codons of the nucleotide sequence to obtain a mutated nucleotide sequence that\n
i) encodes the same amino acid sequence as the unrearranged nucleotide sequences, and\n
ii) has a reduced codon pair bias compared to the unrearranged nucleotide sequence; and\n
c) substituting all or part of the mutated nucleotide sequences into the unrearranged nucleotides of the influenza virus genome."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 21, wherein polymerase protein is PB1 and the virion protein is hemagglutinin (HA)."],"number":22,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}