11beta-hsd1 Active Compounds

  • Published: Oct 2, 2008
  • Earliest Priority: Mar 28 2007
  • Family: 9
  • Cited Works: 2
  • Cited by: 16
  • Cites: 1
  • Additional Info: Cited Works Full text

A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11ß -hydroxysteroid dehydrogenase type 1 (11ßHSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.

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Document History
  • Publication: Oct 2, 2008
  • Application: Mar 27, 2008
    WO US 2008/0058432 W
  • Priority: Mar 28, 2007
    US US 92043307 P

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