Companion Diagnostic For Cdk4 Inhibitors

  • Published: Feb 13, 2018
  • Earliest Priority: Apr 16 2013
  • Family: 9
  • Cited Works: 105
  • Cited by: 0
  • Cites: 6
  • Sequences: 10
  • Additional Info: Cited Works Full text
Data obtained from: EMBL-EBI Pat NCBI GenBank USPTO Fulltext DDBJ Pat
10 sequences found in this patent (in total)

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Download sequences in fasta format: 3 peptides 7 nucleotides

Displaying 1 - 10 of 10 sequences

SEQ ID NO
Length
Sequence Type
Locations
Declared organism
Determined organism
Occurrence
Tools
SEQ ID NO
1
Length
497
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:89993689
      NP_002383
      1 of 4 hits reported for Homo sapiens.
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      1,021.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_002383
      100% cov
    • Alignment Length
      497 aa
    • CIGAR string
      497M mismatches: 0 - insertions: 0 - deletions: 0
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:114645762
      XP_001155208
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      1,018.5 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_001155208
      100% cov
    • Alignment Length
      497 aa
    • CIGAR string
      282MN148MN65M mismatches: 2 - insertions: 0 - deletions: 0
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:297262920
      XP_001117336
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      1,016.5 bits
    • Similarity
      99.8%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_001117336
      100% cov
    • Alignment Length
      497 aa
    • CIGAR string
      270MN11MN93MN120M mismatches: 3 - insertions: 0 - deletions: 0
  • Nomascus leucogenys

    Nomascus leucogenys

    • Public DB hit
      GI:332221392
      XP_003259844
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      1,015 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_003259844
      100% cov
    • Alignment Length
      497 aa
  • Pongo abelii

    Pongo abelii

    • Public DB hit
      GI:197100702
      NP_001124685
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      1,012.7 bits
    • Similarity
      99.6%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_001124685
      100% cov
    • Alignment Length
      497 aa
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:30584709
      AAP36607
    • Hit length
      492 aa
    • E Value
      0E0
    • BLAST Score
      1,009.2 bits
    • Similarity
      100%
    • Coverage
      98.79%
    • Alignment (schematic)

      SEQ ID NO 1
      98.79% cov
      AAP36607
      99.8% cov
    • Alignment Length
      491 aa
  • Equus caballus

    Equus caballus

    • Public DB hit
      GI:8472521
      P56951
    • Hit length
      491 aa
    • E Value
      0E0
    • BLAST Score
      901 bits
    • Similarity
      97.56%
    • Coverage
      98.79%
    • Alignment (schematic)

      SEQ ID NO 1
      98.79% cov
      P56951
      100% cov
    • Alignment Length
      491 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:157427730
      NP_001098773
    • Hit length
      491 aa
    • E Value
      0E0
    • BLAST Score
      900.2 bits
    • Similarity
      95.93%
    • Coverage
      98.79%
    • Alignment (schematic)

      SEQ ID NO 1
      98.79% cov
      NP_001098773
      100% cov
    • Alignment Length
      491 aa
  • Felis catus

    Felis catus

    • Public DB hit
      GI:57163889
      NP_001009346
    • Hit length
      491 aa
    • E Value
      0E0
    • BLAST Score
      897.9 bits
    • Similarity
      96.74%
    • Coverage
      98.79%
    • Alignment (schematic)

      SEQ ID NO 1
      98.79% cov
      NP_001009346
      100% cov
    • Alignment Length
      491 aa
  • Bos taurus

    Bos taurus

    • Public DB hit
      GI:149642933
      NP_001092577
      1 of 2 hits reported for Bos taurus.
    • Hit length
      492 aa
    • E Value
      0E0
    • BLAST Score
      896.7 bits
    • Similarity
      97.36%
    • Coverage
      98.79%
    • Alignment (schematic)

      SEQ ID NO 1
      98.79% cov
      NP_001092577
      100% cov
    • Alignment Length
      492 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:281347891
      EFB23475
      1 of 2 hits reported for Ailuropoda melanoleuca.
    • Hit length
      489 aa
    • E Value
      0E0
    • BLAST Score
      896 bits
    • Similarity
      96.15%
    • Coverage
      99.2%
    • Alignment (schematic)

      SEQ ID NO 1
      99.2% cov
      EFB23475
      100% cov
    • Alignment Length
      493 aa
Occurrence
84 times in PatSeqDB
Tools
SEQ ID NO
2
Length
489
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Mus musculus
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:6754672
      NP_034916
      1 of 6 hits reported for Mus musculus.
    • Hit length
      489 aa
    • E Value
      0E0
    • BLAST Score
      1,001.5 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_034916
      100% cov
    • Alignment Length
      489 aa
    • CIGAR string
      489M mismatches: 0 - insertions: 0 - deletions: 0
  • Mus caroli

    Mus caroli

    • Public DB hit
      GI:51471144
      AAU04329
    • Hit length
      487 aa
    • E Value
      0E0
    • BLAST Score
      863.2 bits
    • Similarity
      97.54%
    • Coverage
      98.57%
    • Alignment (schematic)

      SEQ ID NO 2
      98.57% cov
      AAU04329
      100% cov
    • Alignment Length
      487 aa
  • Rattus norvegicus

    Rattus norvegicus

    • Public DB hit
      GI:157821747
      NP_001101569
    • Hit length
      458 aa
    • E Value
      0E0
    • BLAST Score
      790.4 bits
    • Similarity
      88.34%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_001101569
      100% cov
    • Alignment Length
      489 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:157427730
      NP_001098773
    • Hit length
      491 aa
    • E Value
      0E0
    • BLAST Score
      744.6 bits
    • Similarity
      86.9%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      NP_001098773
      99.8% cov
    • Alignment Length
      496 aa
  • Equus caballus

    Equus caballus

    • Public DB hit
      GI:8472521
      P56951
    • Hit length
      491 aa
    • E Value
      0E0
    • BLAST Score
      738.8 bits
    • Similarity
      87.3%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      P56951
      99.8% cov
    • Alignment Length
      496 aa
  • Bos taurus

    Bos taurus

    • Public DB hit
      GI:296487692
      DAA29805
      1 of 2 hits reported for Bos taurus.
    • Hit length
      492 aa
    • E Value
      0E0
    • BLAST Score
      738.8 bits
    • Similarity
      87.12%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      DAA29805
      99.8% cov
    • Alignment Length
      497 aa
  • Felis catus

    Felis catus

    • Public DB hit
      GI:57163889
      NP_001009346
    • Hit length
      491 aa
    • E Value
      0E0
    • BLAST Score
      735.3 bits
    • Similarity
      86.9%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      NP_001009346
      99.8% cov
    • Alignment Length
      496 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:281347891
      EFB23475
      1 of 2 hits reported for Ailuropoda melanoleuca.
    • Hit length
      489 aa
    • E Value
      0E0
    • BLAST Score
      733.4 bits
    • Similarity
      86.49%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      EFB23475
      99.39% cov
    • Alignment Length
      496 aa
  • Pongo abelii

    Pongo abelii

    • Public DB hit
      GI:197100702
      NP_001124685
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      726.9 bits
    • Similarity
      86.9%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      NP_001124685
      98.59% cov
    • Alignment Length
      496 aa
  • Canis lupus familiaris

    Canis lupus familiaris

    • Public DB hit
      GI:9884635
      BAB11975
    • Hit length
      487 aa
    • E Value
      0E0
    • BLAST Score
      725.7 bits
    • Similarity
      85.48%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      BAB11975
      99.79% cov
    • Alignment Length
      496 aa
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:297262920
      XP_001117336
    • Hit length
      497 aa
    • E Value
      0E0
    • BLAST Score
      724.9 bits
    • Similarity
      86.69%
    • Coverage
      99.8%
    • Alignment (schematic)

      SEQ ID NO 2
      99.8% cov
      XP_001117336
      98.59% cov
    • Alignment Length
      496 aa
Occurrence
15 times in PatSeqDB
Tools
SEQ ID NO
3
Length
458
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Rattus norvegicus
Determined organism
Occurrence
5 times in PatSeqDB
Tools
SEQ ID NO
4
Length
21
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:170932495
      NG_007484
      1 of 10 hits reported for Homo sapiens.
    • Hit length
      11,162 bp
    • E Value
      2.55E-2
    • BLAST Score
      42.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      NG_007484
      0.19% cov
    • Alignment Length
      21 bp
    • CIGAR string
      21M mismatches: 0 - insertions: 0 - deletions: 0
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:332838814
      XM_509173
      1 of 2 hits reported for Pan troglodytes.
    • Hit length
      2,153 bp
    • E Value
      2.55E-2
    • BLAST Score
      42.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XM_509173
      0.98% cov
    • Alignment Length
      21 bp
    • CIGAR string
      21M mismatches: 0 - insertions: 0 - deletions: 0
  • Pongo abelii

    Pongo abelii

    • Public DB hit
      GI:297692270
      XM_002823440
      1 of 4 hits reported for Pongo abelii.
    • Hit length
      2,023 bp
    • E Value
      2.55E-2
    • BLAST Score
      42.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XM_002823440
      1.04% cov
    • Alignment Length
      21 bp
    • CIGAR string
      21M mismatches: 0 - insertions: 0 - deletions: 0
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:297262809
      XM_001116422
      1 of 2 hits reported for Macaca mulatta.
    • Hit length
      1,399 bp
    • E Value
      2.55E-2
    • BLAST Score
      42.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XM_001116422
      1.5% cov
    • Alignment Length
      21 bp
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:296212173
      XM_002752669
      1 of 6 hits reported for Callithrix jacchus.
    • Hit length
      1,509 bp
    • E Value
      2.55E-2
    • BLAST Score
      42.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      XM_002752669
      1.39% cov
    • Alignment Length
      21 bp
  • Macaca fascicularis

    Macaca fascicularis

    • Public DB hit
      GI:90086034
      AB174508
    • Hit length
      1,334 bp
    • E Value
      2.55E-2
    • BLAST Score
      42.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      AB174508
      1.57% cov
    • Alignment Length
      21 bp
Occurrence
9 times in PatSeqDB
Tools
SEQ ID NO
5
Length
21
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
5 times in PatSeqDB
Tools
SEQ ID NO
6
Length
21
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
6 times in PatSeqDB
Tools
SEQ ID NO
7
Length
21
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
5 times in PatSeqDB
Tools
SEQ ID NO
8
Length
21
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
5 times in PatSeqDB
Tools
SEQ ID NO
9
Length
21
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
5 times in PatSeqDB
Tools
SEQ ID NO
10
Length
24
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
5 times in PatSeqDB
Tools

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