Use Of Panton-valentine Leukocidin For Treating And Preventing Staphylococcus Infections

  • Published: Mar 2, 2011
  • Earliest Priority: Jun 13 2005
  • Family: 20
  • Cited Works: 54
  • Cited by: 0
  • Cites: 9
  • Additional Info: Cited Works Published
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Abstract

The present invention relates to compositions and methods for treating Staphylococcus aureus ( S. aureus ) infections. In particular, the present invention provides vaccines comprising a Panton-Valentine Leukocidin (PVL) antigen, antibodies which bind a PVL antigen and compositions containing the same, methods of making such compositions and methods for treating S . aureus infections, including those that are community acquired methicillin-resistant infections. The present invention also provides PVL antibodies, including PVL antibodies specific for a single PVL subunit, and PVL antigens, including conjugated and mutated PVL antigens.


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Document History
  • Publication: Mar 2, 2011
  • Application: Jun 13, 2006
    EP EP 10180402 A
  • Priority: Jun 13, 2006
    EP EP 06784845 A
  • Priority: Jun 13, 2005
    US US 68952605 P

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