Nutritional Support To Prevent And/or Mitigate Bone Marrow Toxicity From A Cancerous Tumor


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The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.


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Document History
  • Publication: Jan 22, 2014
  • Application: Sep 11, 2009
    EP EP 13189251 A
  • Priority: Sep 11, 2009
    EP EP 09792442 A
  • Priority: Sep 10, 2009
    US US 24107409 P
  • Priority: Sep 19, 2008
    US US 9825808 P

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