Coq10 (ubiquinone, Ubiquinol), Vitamin A (retinoic Acid, Retinol), Vitamin E (tocotrienol, Tocopherol) And Methods Of Use

  • Published: Jan 25, 2017
  • Earliest Priority: Jul 03 2013
  • Family: 8
  • Cited Works: 3
  • Cited by: 0
  • Cites: 6
  • Additional Info: Cited Works
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Abstract

CoQ10 and vitamin E are both lipid-soluble nutrients with redox potential. Tocopherol and/or tocotrienol protect CoQ10 from oxidative damage and reduce ubiquinone in situ. Specifically, vitamin E protects the oxidation of ubiquinol to ubiquinone ex vivo and reduces ubiquinone to ubiquinol in situ. Vitamin Es with higher ratio of tocotrienol-to-tocopherol cause a higher ratio of ubiquinol-to-ubiquinone. Additionally tocopherol and/or tocotrienol protect vitamin A oxidation from retinol to retinoic acid.


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Document History
  • Publication: Jan 25, 2017
  • Application: Jul 3, 2014
    EP EP 14819403 A
  • Priority: Jul 3, 2014
    US US 2014/0045477 W
  • Priority: Jul 3, 2013
    US US 201361842732 P

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