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The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"}]},"abstract_lang":["en"],"has_abstract":true,"claim":{"en":[{"text":"1. A method for determining whether a test compound is a hepatotoxin, comprising: (a) exposing liver tissue or liver cells to the test compound; (b) preparing a normalized gene expression profile of at least ten genes for said liver tissue or liver cells, wherein the gene expression profile contains the differential gene expression levels for said at least ten genes upon exposure to the test compound, and wherein said at least ten genes are listed in one of Tables 3-3DD; (c) comparing the gene expression profile to a hepatotoxicity model, the hepatotoxicity model comprising: (i) the normalized mean expression levels of said at least ten genes in liver tissue or liver cells exposed to a known hepatotoxin, (ii) the normalized mean expression levels of said at least ten genes in liver tissue or liver cells not exposed to a hepatotoxin, and (iii) information from one or more of Tables 3-3DD; and (d) scoring the comparison to determine whether the test compound is a hepatotoxin.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"2. The method of claim 1 , wherein the gene expression profile contains the differential gene expression levels for at least 20 genes listed in one of Tables 3-3DD, and wherein the hepatotoxicity model comprises the gene expression levels in said one of Tables 3-3DD.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"3. The method of claim 1 , wherein said gene expression profile is generated by hybridization of nucleic acids to a microarray, and is normalized for hybridization conditions, label intensity, and reading efficiency prior to comparison.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"4. The method of claim 1 , wherein the hepatotoxicity model comprises all the information in one of Tables 3-3DD.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"5. The method of claim 1 , wherein the liver tissue or liver cells are exposed to the test compound in vivo and the hepatotoxicity model is generated by exposure of liver tissue or liver cells to the known hepatotoxin in vivo.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"6. The method of claim 1 , wherein the known hepatotoxin is associated with at least one of hepatitis, liver necrosis, protein adduct formation and fatty liver.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"7. The method of claim 1 , wherein the known hepatotoxin is one or more of acetominophen, acyclovir, ANIT, AY-25329, bicalutamide, carbon tetrachloride, clofibrate, cyproterone acetate, diclofenac, diflunisal, dioxin, estradiol, hydrazine, indomethacin, LPS, phenobarbitol, tacrine, valproate, WY-14643, and zileuton.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"8. The method of claim 1 , wherein the gene expression profile contains the differential gene expression levels for at least 30 genes listed in one of Tables 3-3DD, and wherein the hepatotoxicity model comprises the gene expression levels in said one of Tables 3-3DD.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"9. The method of claim 1 , wherein the gene expression profile contains the differential gene expression levels for at least 50 genes listed in one of Tables 3-3DD, and wherein the hepatotoxicity model comprises the gene expression levels in said one of Tables 3-3DD.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"},{"text":"10. The method of claim 1 , wherein the comparison is scored by determining whether the test compound induces a change in expression of the at least 10 genes in the same direction as the known hepatotoxin.","lang":"en","source":"USPTO_FULLTEXT","data_format":"ORIGINAL"}]},"claim_lang":["en"],"has_claim":true,"description":{"en":{"text":"RELATED APPLICATIONS This is application is a divisional application of U.S. application Ser. No. 10/060,087 filed Jan. 31, 2002, now abandoned, which claims the benefit of U.S. Provisional Application No. 60/331,273 filed Nov. 13, 2001 and is a continuation-in-part of U.S. application Ser. No. 09/917,800, filed Jul. 31, 2001, now abandoned, which claims the benefit of U.S. Provisional Applications 60/303,459, filed Jul. 9, 2001; 60/298,884, filed Jun. 19, 2001; 60/297,457, filed Jun. 13, 2001; 60/295,798, filed Jun. 6, 2001; 60/292,336, filed May 22, 2001; 60/290,645, filed May 15, 2001; 60/290,029, filed May 11, 2001; 60/244,880, filed Nov. 2, 2000; and 60/222,040, filed Jul. 31, 2000, all of which are herein incorporated by reference in their entirety. SEQUENCE LISTING SUBMISSION ON COMPACT DISC The Sequence Listing submitted concurrently herewith on compact disc under 37 C.F.R. §§1.821(c) and 1.821(e) is herein incorporated by reference in its entirety. Three copies of the Sequence Listing, one on each of three compact discs are provided. Copy 1 and Copy 2 are identical. Copies 1 and 2 are also identical to the CRF. Each electronic copy of the Sequence Listing was created on Jan. 30, 2002 with a file size of 3083 KB. The file names are as follows: Copy 1—GL5038U1.txt; Copy 2—GL5038U1.txt; CRF—GL5038U1.txt. BACKGROUND OF THE INVENTION The need for methods of assessing the toxic impact of a compound, pharmaceutical agent or environmental pollutant on a cell or living organism has led to the development of procedures which utilize living organisms as biological monitors. The simplest and most convenient of these systems utilize unicellular microorganisms such as yeast and bacteria, since they are most easily maintained and manipulated. Unicellular screening systems also often use easily detectable changes in phenotype to monitor the effect of test compounds on the cell. Unicellular organisms, however, are inadequate models for estimating the potential effects of many compounds on complex multicellular animals, as they do not have the ability to carry out biotransformations to the extent or at levels found in higher organisms. The biotransformation of chemical compounds by multicellular organisms is a significant factor in determining the overall toxicity of agents to which they are exposed. Accordingly, multicellular screening systems may be preferred or required to detect the toxic effects of compounds. The use of multicellular organisms as toxicology screening tools has been significantly hampered, however, by the lack of convenient screening mechanisms or endpoints, such as those available in yeast or bacterial systems. In addition, previous attempts to produce toxicology prediction systems have failed to provide the necessary modeling data and statistical information to accurately predict toxic responses (e.g., WO 00/12760, WO 00/47761, WO 00/63435, WO 01/32928, WO 01/38579, and the Affymetrix® Rat Tox Chip. SUMMARY OF THE INVENTION The present invention is based on the elucidation of the global changes in gene expression in liver tissues or cells exposed to known toxins, in particular hepatotoxins, as compared to unexposed tissues or cells as well as the identification of individual genes that are differentially expressed in liver tissues or cells upon toxin exposure. In various aspects, the invention includes methods of predicting at least one toxic effect of a compound, predicting the progression of a toxic effect of a compound, and predicting the hepatoxicity of a compound. The invention also includes methods of identifying agents that modulate the onset or progression of a toxic response. Also provided are methods of predicting the cellular pathways that a compound modulates in a cell. The invention includes methods of identifying agents that modulate protein activities. In a further aspect, the invention provides probes comprising sequences that specifically hybridize to genes in Tables 1-3. Also provided are solid supports comprising at least two of the previously mentioned probes. The invention also includes a computer system that has a database containing information identifying the expression level in a tissue or cell sample exposed to a hepatotoxin of a set of genes comprising at least two genes in Tables 1-3. DETAILED DESCRIPTION Many biological functions are accomplished by altering the expression of various genes through transcriptional (e.g. through control of initiation, provision of RNA precursors, RNA processing, etc.) and/or translational control. For example, fundamental biological processes such as cell cycle, cell differentiation and cell death are often characterized by the variations in the expression levels of groups of genes. Changes in gene expression are also associated with the effects of various chemicals, drugs, toxins, pharmaceutical agents and pollutants on an organism or cells. For example, the lack of sufficient expression of functional tumor suppressor genes and/or the over expression of oncogene/protooncogenes after exposure to an agent could lead to tumorgenesis or hyperplastic growth of cells (Marshall, Cell, 64: 313-326 (1991); Weinberg, Science, 254:1138-1146 (1991)). Thus, changes in the expression levels of particular genes (e.g. oncogenes or tumor suppressors) may serve as signposts for the presence and progression of toxicity or other cellular responses to exposure to a particular compound. Monitoring changes in gene expression may also provide certain advantages during drug screening and development. Often drugs are screened for the ability to interact with a major target without regard to other effects the drugs have on cells. These cellular effects may cause toxicity in the whole animal, which prevents the development and clinical use of the potential drug. The present inventors have examined tissue from animals exposed to the known hepatotoxins which induce detrimental liver effects, to identify global changes in gene expression induced by these compounds. These global changes in gene expression, which can be detected by the production of expression profiles, provide useful toxicity markers that can be used to monitor toxicity and/or toxicity progression by a test compound. Some of these markers may also be used to monitor or detect various disease or physiological states, disease progression, drug efficacy and drug metabolism. Identification of Toxicity Markers To evaluate and identify gene expression changes that are predictive of toxicity, studies using selected compounds with well characterized toxicity have been conducted by the present inventors to catalogue altered gene expression during exposure in vivo and in vitro. In the present study, acyclovir, amitryptiline, alpha-naphthylisothiocyante (ANIT), acetaminophen, AY-25329, bicalutamide, carbon tetrachloride, clofibrate, cyproterone acetate (CPA), diclofenac, diflunisal, dioxin, 17α-ethinylestradiol, hydrazine, indomethacin, lipopolysaccharide, phenobarbital, tacrine, valproate, WY-14643 and zileuton were selected as a known hepatotoxins. The pathogenesis of acute CCl 4 -induced hepatotoxicity follows a well-characterized course in humans and experimental animals resulting in centrilobular necrosis and steatosis, followed by hepatic regeneration and tissue repair. Severity of the hepatocellular injury is also dose-dependent and may be affected by species, age, gender and diet. Differences in susceptibility to CCl 4 hepatotoxicity are primarily related to the ability of the animal model to metabolize CCl 4 to reactive intermediates. CCl 4 -induced hepatotoxicity is dependent on CCl 4 bioactivation to trichloromethyl free radicals by cytochrome P450 enzymes (CYP2E1), localized primarily in centrizonal hepatocytes. Formation of the free radicals leads to membrane lipid peroxidation and protein denaturation resulting in hepatocellular damage or death. The onset of hepatic injury is rapid following acute administration of CCl 4 to male rats. Morphologic studies have shown cytoplasmic accumulation of lipids in hepatocytes within 1 to 3 hours of dosing, and by 5 to 6 hours, focal necrosis and hydropic swelling of hepatocytes are evident. Centrilobular necrosis and inflammatory infiltration peak by 24 to 48 hours post dose. The onset of recovery is also evident within this time frame by increased DNA synthesis and the appearance of mitotic figures. Removal of necrotic debris begins by 48 hours and is usually completed by one week, with full restoration of the liver by 14 days. Increases in serum transaminase levels also parallel CCl 4 -induced hepatic histopathology. In male Sprague Dawley (SD) rats, alanine aminotrasferase (ALT) and aspartate aminotransferase (AST) levels increase within 3 hours of CCl 4 administration (0.1, 1, 2, 3, 4 mL/kg, ip; 2.5 mL/kg, po) and reach peak levels (approximately 5-10 fold increases) within 48 hours post dose. Significant increases in serum α-glutathione s-transferase (α-GST) levels have also been detected as early as 2 hours after CCl 4 administration (25 μL/kg, po) to male SD rats. At the molecular level, induction of the growth-related proto-oncogenes, c-fos and c-jun, is reportedly the earliest event detected in an acute model of CCl 4 -induced hepatotoxicity (Schiaffonato et al., Liver 17:183-191 (1997)). Expression of these early-immediate response genes has been detected within 30 minutes of a single dose of CCl 4 to mice (0.05-1.5 mL/kg, ip) and by 1 to 2 hours post dose in rats (2 mL/kg, po; 5 mL/kg, po) (Schiaffonato et al., supra, and Hong et al., Yonsei Medical J 38:167-177 (1997)). Similarly, hepatic c-myc gene expression is increased by 1 hour following an acute dose of CCl 4 to male SD rats (5 mL/kg, po) (Hong et al., sup{dot over (r)}a). Expression of these genes following exposure to CCl 4 is rapid and transient. Peak hepatic mRNA levels for c-fos, c-jun, and c-myc, after acute administration of CCl 4 have been reported at 1 to 2 hours, 3 hours, and 1 hour post dose, respectively. The expression of tumor necrosis factor-α (TNF-α) is also increased in the livers of rodents exposed to CCl 4 , and TNF-α has been implicated in initiation of the hepatic repair process. Pre-treatrnent with anti-TNF-α antibodies has been shown to prevent CCl 4 -mediated increases in c-jun and c-fos gene expression, whereas administration of TNF-α induced rapid expression of these genes (Bruccoleri et al., Hepatol 25:133-141 (1997)). Up-regulation of transforming growth factor-β (TGF-β) and transforming growth factor receptors (TBRI-III) later in the repair process (24 and 48 hours after CCl 4 administration) suggests that TGF-β may play a role in limiting the regenerative response by induction of apoptosis (Grasl-Kraupp et al., Hepatol 28:717-7126 (1998)). Acetaminophen is a widely used analgesic that at supratherapeutic doses can be metabolized to N-acetyl-p-benzoquinone imine (NAPQI) which causes hepatic and renal failure. At the molecular level, until the present invention little was known about the effects of acetominophen. Amitriptyline is a commonly used antidepressant, although it is recognized to have toxic effects on the liver ( Physicians Desk Reference, 47 th ed., Medical Economics Co., Inc., 1993; Balkin, U.S. Pat. No. 5,656,284). Nevertheless, amitriptyline's beneficial effects on depression, as well as on sleep and dyspepsia (Mertz et al., Am J Gastroenterol 93(2):160-165 (1998)), migraines (Beubler, Wien Med Wochenschr 144(5-6):100-101 (1994)), arterial hypertension (Bobkiewicz et al., Arch Immunol Ther Exp ( Warsz ) 23(4):543-547 (1975)) and premature ejaculation (Smith et al., U.S. Pat. No. 5,923,341) mandate its continued use. Differences in susceptibility to amitriptyline toxicity are considered related to differential metabolism. Amitriptyline-induced hepatotoxicity is primarily mediated by development of cholestasis, the condition caused by the failure of the liver to secrete bile, resulting in accumulation in blood plasma of substances normally secreted into bile-bilirubin and bile salts. Cholestasis is also characterized by liver cell necrosis and bile duct obstruction, which leads to increased pressure on the lumenal side of the canalicular membrane and release of enzymes (alkaline phosphatase, 5′-nucleotidase, gammaglutamyl transpeptidase) normally localized on the canalicular membrane. These enzymes also begin to accumulate in the plasma. Typical symptoms of cholestasis are general malaise, weakness, nausea, anorexia and severe pruritis (Cecil Textbook of Medicine, 20 th ed., part XII, pp. 772-773, 805-808, J. C. Bennett and F. Plum Eds., W. B. Saunders Co., Philadelphia, 1996). The effects of amitriptyline or phenobarbital (PB) on phospholipid metabolism in rat liver have been studied. In one study, male Sprague-Dawley rats received amitriptyline orally in one dose of 600 mg/kg. PB was given intraperitonially (IP) at a dosage of 80 mg/kg. Animals were sacrificed by decapitation at 6, 12, 18, and 24 hr. The phospholipid level in liver was measured by enzymatic assay and by gas chromatography-mass spectrometry. Both agents caused an increase in the microsomal phosphatidylcholine content. Levels of glycerophosphate acyltransferase (GAT) and phosphatidate cytidylyltransferase (PCT) were slightly affected by amitriptyline but were significantly affected by PB. Levels of phosphatidate phosphohydrolase (PPH) and choline phosphotransferase (CPT) were significantly altered by amitriptyline and by PB (Hoshi et al., Chem Pharm Bull 38:3446-3448 (1990)). In another experiment, amitriptyline was given orally to male Sprague-Dawley rats (4-5 weeks old) in a single dose of 600 mg/kg. The animals were sacrificed 12 or 24 hours later. This caused a marked increase in -aminolevulinic acid (-ALA) activity at both time points. Total heme and cytochrome b5 levels were increased but cytochrome P450 (CYP450) content remained the same. The authors concluded that hepatic heme synthesis is increased through prolonged induction of -ALA but this may be accounted for by the increases in cytochrome b5 and total heme and not by the CYP450 content (Hoshi et al., Jpn J Pharmacol 50:289-293 (1989)). Amitriptyline can cause hypersensititivity syndrome, a specific severe idiosyncratic reaction characterized by skin, liver, joint and haematological abnormalities (Milionis et al., Postgrad Med 76(896):361-363 (2000)). Amitriptyline has also been shown to cause drug-induced hepatitis, resulting in liver peroxisomes with impaired catalase function (De Creaemer et al., Hepatology 14(5):811-817 (1991)). The peroxisomes are larger in number, but smaller in size and deformed in shape. Using cultured hepatocytes, the cytotoxicity of amitriptyline was examined and compared to other psychotropic drugs (Boelsterli et al., Cell Biol Toxicol 3(3):231-250 (1987)). The effects observed were release of lactate dehydrogenase from the cytosol, as well as impairment of biosynthesis and secretion of proteins, bile acids and glycolipids. Aromatic and aliphatic isothiocyanates are commonly used soil fumigants and pesticides (Shaaya et al., Pesticide Science 44(3):249-253 (1995); Cairns et al., J Assoc Official Analytical Chemists 71(3):547-550 (1988)). These compounds are also environmental hazards, however, because they remain as toxic residues in plants, either in their original or in a metabolized form (Cerny et al., J Agricultural and Food Chemistry 44(12):3835-3839 (1996)) and because they are released from the soil into the surrounding air (Gan et al., J Agricutural and Food Chemistry 46(3):986-990 (1998)). Alpha-naphthylthiourea, an amino-substituted form of ANIT, is a known rodenticide whose principal toxic effects are pulmonary edema and pleural effusion, resulting from the action of this compound on pulmonary capillaries. Microsomes from lung and liver release atomic sulfur (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9 th ed., chapter 67, p. 1690, J. G. Hardman et al. eds., McGraw-Hill, New York, N.Y., 1996). In one study in rats, ANIT (80 mg/kg) was dissolved in olive oil and given orally to male Wistar rats (180-320 g). All animals were fasted for 24 hours before ANIT treatment, and blood and bile excretion were analyzed 24 hours later. Levels of total bitimbin, alkaline phosphatase, serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase were found to be significantly increased, while ANIT reduced total bile flow, all of which are indications of severe biliary dysfunction. This model is used to induce cholestasis with jaundice because the injury is reproducible and dose-dependent. ANIT is metabolized by microsomal enzymes, and a metabolite plays a fundamental role in its toxicity (Tanaka et al., Clinical and Experimental Pharmacology and Physiology 20:543-547 (1993))(92). ANIT fails to produce extensive necrosis, but has been found to produce inflammation and edema in the portal tract of the liver (Maziasa et al., Toxicol Appl Pharmacol 110:365-373 (1991)). Livers treated with ANIT are significantly heavier than control-treated counterparts and serum levels of alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (-GTP), total bilirubin, lipid peroxide and total bile acids showed significant increases (Anonymous, Toxicol Lett 105:103-110 (2000)). ANIT-induced hepatotoxicity may also be characterized by cholangiolitic hepatitis and bile duct damage. Acute hepatotoxicity caused by ANIT in rats is manifested as neutrophil-dependent necrosis of bile duct epithelial cells (BDECs) and hepatic parenchymal cells. These changes mirror the cholangiolitic hepatitis found in humans (Hill, Toxicol Sci 47:118-125 (1999)). Exposure to ANIT also causes liver injury by the development of cholestasis, the condition caused by failure to secrete bile, resulting in accumulation in blood plasma of substances normally secreted into bile, such as bilirubin and bile salts. Cholestasis is also characterized by liver cell necrosis, including bile duct epithelial cell necrosis, and bile duct obstruction, which leads to increased pressure on the lumenal side of the canalicular membrane, decreased canalicular flow and release of enzymes normally localized on the canalicular membrane (alkaline phosphatase, 5′-nucleotidase, gammaglutamyl transpeptidase). These enzymes also begin to accumulate in the plasma. Typical symptoms of cholestasis are general malaise, weakness, nausea, anorexia and severe pruritis (Cecil Textbook of Medicine, 20 th ed., part XII, pp. 772-773, 805-808, J. C. Bennett and F. Plum Eds., W. B. Saunders Co., Philadelphia (1996) and Kossor et al., Toxicol Appl Pharmacol 119:108-114 (1993)). ANIT-induced cholestatis is also characterized by abnormal serum levels of alanine aminotransferase, aspartic acid aminotransferase and total bilirubin. In addition, hepatic lipid peroxidation is increased, and the membrane fluidity of microsomes is decreased. Histological changes include an infiltration of polymorphonuclear neutrophils and elevated number of apoptotic hepatocytes (Calvo et al., J Cell Biochem 80(4):461-470 (2001)). Other known hepatotoxic effects of exposure to ANIT include a damaged antioxidant defense system, decreased activities of superoxide dismutase and catalase (Ohta et al., Toxicology 139(3):265-275 (1999)), and the release of several proteases from the infiltrated neutrophils, alanine aminotransferase, cathepsin G, elastase, which mediate hepatocyte killing (Hill et al., Toxicol Appl Pharmacol 148(1): 169-175 (1998)). Indomethacin is a non-steroidal antiinflammatory, antipyretic and analgesic drug commonly used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout and a type of severe, chronic cluster headache characterized by many daily occurrences and jabbing pain. This drug acts as a potent inhibitor of prostaglandin synthesis; it inhibits the cyclooxygenase enzyme necessary for the conversion of arachidonic acid to prostaglandins (PDR 47 th ed., Medical Economics Co., Inc., Montvale, N.J., 1993; Goodman & Gilman's The Pharmalogical Basis of Therapeutics 9 th ed., J. G. Hardman et al. eds., McGraw Hill, New York, 1996, pp. 1074-1075, 1089-1095; Cecil Textbook of Medicine, 20 th ed., part XII, pp. 772-773, 805-808, J. C. Bennett and F. Plum Eds., W. B. Saunders Co., Philadelphia, 1996). The most frequent adverse effects of indomethacin treatment are gastrointestinal disturbances, usually mild dyspepsia, although more severe conditions, such as bleeding, ulcers and perforations can occur. Hepatic involvement is uncommon, although some fatal cases of hepatitis and jaundice have been reported. Renal toxicity can also result, particularly after long-term administration. Renal papillary necrosis has been observed in rats, and interstitial nephritis with hematuria, proteinuria and nephrotic syndrome have been reported in humans. Patients suffering from renal dysfunction risk developing a reduction in renal blood flow, because renal prostaglandins play an important role in renal perfusion. In rats, although indomethacin produces more adverse effects in the gastrointestinal tract than in the liver, it has been shown to induce changes in hepatocytic cytochrome P450. In one study, no widespread changes in the liver were observed, but a mild, focal, centrilobular response was noted. Serum levels of albumin and total protein were significantly reduced, while the serum level of urea was increased. No changes in creatinine or aspartate aminotransferase (AST) levels were observed (Falzon et al., Br J exp Path 66:527-534 (1985)). In another rat study, a single dose of indomethacin has been shown to reduce liver and renal microsomal enzymes, including CYP450, within 24 hours. Histopathological changes were not monitored, although there were lesions in the GI tract. The effects on the liver seemed to be waning by 48 hours (Fracasso et al., Agents Actions 31:313-316, (1990)). A study of hepatocytes, in which the relative toxicity of five nonsteroidal antiinflammatory agents was compared, showed that indomethacin was more toxic than the others. Levels of lactate dehydrogenase release and urea, as well as viability and morphology, were examined. Cells exposed to high levels of indomethacin showed cellular necrosis, nuclear pleomorphism, swollen mitochondria, fewer microvilli, smooth endoplasmic reticulum proliferation and cytoplasmic vacuolation (Sorensen et al., J Toxicol Environ Health 16(3-4); 425-440 (1985)). 17α-ethinylestradiol, a synthetic estrogen, is a component of oral contraceptives, often combined with the progestational compound norethindrone. It is also used in post-menopausal estrogen replacement therapy (PDR 47 th ed., pp. 2415-2420, Medical Economics Co., Inc., Montvale, N.J., 1993; Goodman & Gilman's The Pharmalogical Basis of Therapeutics 9 th ed., pp. 1419-1422, J. G. Hardman et al. Eds., McGraw Hill, New York, 1996). The most frequent adverse effects of 17α-ethinylestradiol usage are increased risks of cardiovascular disease: myocardial infarction, thromboembolism, vascular disease and high blood pressure, and of changes in carbohydrate metabolism, in particular, glucose intolerance and impaired insulin secretion. There is also an increased risk of developing benign hepatic neoplasia, although the incidence of this disease is very low. Because this drug decreases the rate of liver metabolism, it is cleared slowly from the liver, and carcinogenic effects, such as tumor growth, may result. In a recent study, 17α-ethinylestradiol was shown to cause a reversible intrahepatic cholestasis in male rats, mainly by reducing the bile-salt-independent fraction of bile flow (BSIF) (Koopen et al., Hepatology 27:537-545 (1998)). Plasma levels of bilirubin, bile salts, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in this study were not changed. This study also showed that 17-ethinylestradiol produced a decrease in plasma cholesterol and plasma triglyceride levels, but an increase in the weight of the liver after 3 days of drug administration, along with a decrease in bile flow. Further results from this study are as follows. The activities of the liver enzymes leucine aminopeptidase and alkaline phosphatase initially showed significant increases, but enzyme levels decreased after 3 days. Bilirubin output increased, although glutathione (GSH) output decreased. The increased secretion of bilirubin into the bile without affecting the plasma level suggests that the increased bilirubin production must be related to an increased degradation of heme from heme-containing proteins. Similar results were obtained in another experiment (Bouchard et al., Liver 13:193-202 (1993)) in which the livers were also examined by light and electron microscopy. Despite the effects of the drug, visible changes in liver tissue were not observed. In another study of male rats, cholestasis was induced by daily subcutaneous injections of 17α-ethinylestradiol for five days. Cholestasis was assessed by measuring the bile flow rate. Rats allowed to recover for five days after the end of drug treatment showed normal bile flow rates (Hamada et al., Hepatology 21:1455-1464 (1995)). An experiment with male and female rats (Mayol, Carcinogenesis 13:2381-2388 (1992)) found that 17α-ethinylestradiol induced acute liver hyperplasia (increase in mitotic index and BrdU staining) after two days of treatment, although growth regression occurred within the first few days of treatment. With long-term treatment, lasting hyperplasia was again observed after three to six months of administration of the drug. Apoptosis increased around day 3 and returned to normal by one week. Additional experiments in this same study showed that proliferating hepatocytes were predominantly located around a periportal zone of vacuolated hepatocytes, which were also induced by the treatment. Chronic induced activation was characterized by flow cytometry on hepatocytes isolated from male rats, and ploidy analysis of hepatocyte cell suspensions showed a considerably increased proportion of diploid hepatocytes. These diploid cells were the most susceptible to drug-induced proliferation. The results from this study support the theory that cell target populations exist that respond to the effects of tumor promoters. The susceptibility of the diploid hepatocytes to proliferation during treatment may explain, at least in part, the behavior of 17-ethinylestradiol as a tumor promoter in the liver. Wy-14643, a tumor-inducing compound that acts in the liver, has been used to study the genetic profile of cells during the various stages of carcinogenic development, with a view toward developing strategies for detecting, diagnosing and treating cancers (Rockett et al., Toxicology 144(1-3):13-29, (2000)). In contrast to other carcinogens, Wy-14643 does not mutate DNA directly. Instead, it acts on the peroxisome proliferator activated receptor-alpha (PPARalpha), as well as on other signaling pathways that regulate growth (Johnson et al., J Steroid Biochem Mol Biol 77(1):59-71 (2001)). The effect is elevated and sustained cell replication, accompanied by a decrease in apoptosis (Rusyn et al., Carcinogenesis 21(12):2141-2145 (2000)). These authors (Rusyn et al.) noted an increase in the expression of enzymes that repair DNA by base excision, but no increased expression of enzymes that do not repair oxidative damage to DNA. In a study on rodents, Johnson et al. noted that Wy-14643 inhibited liver-X-receptor-mediated transcription in a dose-dependent manner, as well as de novo sterol synthesis. In experiments with mouse liver cells (Peters et al., Carcinogenesis 19(11):1989-1994 (1998), exposure to Wy-14643 produced increased levels of acyl CoA oxidase and proteins involved in cell proliferation: CDK-1, 2 and 4, PCNA and c-myc. Elevated levels may be caused by accelerated transcription that is mediated directly or indirectly by PPARalpha. It is likely that the carcinogenic properties of peroxisome proliferators are due to the PPARalpha-dependent changes in levels of cell cycle regulatory proteins. Another study on rodents (Keller et al., Biochim Biophys Acta 1102(2):237-244 (1992)) showed that Wy-14643 was capable of uncoupling oxidative phosphorylation in rat liver mitochondria. Rates of urea synthesis from ammonia and bile flow, two energy-dependent processes, were reduced, indicating that the energy supply for these processes was disrupted as a result of cellular exposure to the toxin. Wy-14643 has also been shown to activate nuclear factor kappaB, NADPH oxidase and superoxide production in Kupffer cells (Rusyn et al., Cancer Res 60(17):4798-4803 (2000)). NADPH oxidase is known to induce mitogens, which cause proliferation of liver cells. CPA is a potent androgen antagonist and has been used to treat acne, male pattern baldness, precocious puberty, and prostatic hyperplasia and carcinoma (Goodman & Gilman's The Pharmacological Basis of Therapeutics 9 th ed., p. 1453, J. G. Hardman et al., Eds., McGraw Hill, New York, 1996). Additionally, CPA has been used clinically in hormone replacement therapy (HRT). CPA is useful in HRT as it protects the endometrium, decreases menopausal symptoms, and lessens osteoporotic fracture risk (Schneider, “The role of antiandrogens in hormone replacement therapy,” Climacteric 3 (Suppl. 2): 21-27 (2000)). Although CPA has numerous clinical applications, it is tumorigenic, mitogenic, and mutagenic. CPA has been used to treat patients with adenocarcinoma of the prostate, however in two documented cases (Macdonald et al., Clin Oncol 13: 135-137 (2001)), patients developed femoral head avascular necrosis following CPA treatment. In one study (Krebs et al., Carcinogenesis 19(2): 241-245 (1998)), Big Blue transgenic F344 rats were giving varying doses of CPA. As the dose of CPA increased, so did the mutation frequency, but a threshold dose was not determined. Another study (Werner et al., Mutat Res 395(2-3): 179-187 (1997)), showed that CPA caused the formation of DNA adducts in primary cultures of human hepatocytes. The authors suggest that the genotoxicity associated with CPA may be due to the double bond in position 6-7 of the steroid. In additional experiments with rats (Kasper et al., Carcinogenesis 17(10): 2271-2274 (1996)), CPA was shown to induce unscheduled DNA synthesis in vitro. After a single oral dose of 100 mg CPA/kg body weight, continuous DNA repair activity was observed after 16 hours. Furthermore, CPA increased the occurrence of S phase cells, which corroborated the mitogenic potential of CPA in rat liver. CPA has also been shown to produce cirrhosis (Garty et al., Eur J Pediatr 158(5): 367-370 (1999)). A child, who had been treated with CPA for over 4 years for hypothalamic syndrome and precocious puberty, developed cirrhosis. Even though the medication was discontinued, the child eventually succumbed to sepsis and multiorgan failure four years later. In one study on rat liver treated with CPA (Bursch et al., Arch Toxicol 69(4): 253-258 (1995)), the expression of clusterin, a marker for apoptosis, was examined and measured by Northern and slot blot analysis. Bursch et al. showed that post-CPA administration, the clusterin mRNA concentration level increased. Moreover, in situ hybridization demonstrated that clusterin was expressed in all hepatocytes, therefore it is not limited to cells in the process of death by apoptosis. Diclofenac, a non-steroidal anti-inflammatory drug, has been frequently administered to patients suffering from rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Following oral administration, diclofenac is rapidly absorbed and then metabolized in the liver by cytochrome P450 isozyme of the CYC2C subfamily (Goodman & Gilman's The Pharmacological Basis of Therapeutics 9 th ed., p. 637, J. G. Hardman et al., eds., McGraw Hill, New York, 1996). In addition, diclofenac has been applied topically to treat pain due to corneal damage (Jayamanne et al., Eye 11(Pt. 1): 79-83 (1997); Dornic et al., “Topical diclofenac sodium in the management of anesthetic abuse keratopathy,” Am J Ophthalmol 125(5): 719-721 (1998)). Although diclofenac has numerous clinical applications, adverse side-effects have been associated with the drug. In one study, out of 16 patients suffering from corneal complications associated with diclofenac use, 6 experienced corneal or scleral melts, three experienced ulceration, and two experienced severe keratopathy (Guidera et al., Ophthalmology 108(5): 936-944 (2001)). Another report described a term newborn who had premature closure of the ductus arteriosus as a result of maternal treatment with diclofenac (Zenker et al., J Perinat Med 26(3): 231-234 (1998)). Although it was only two weeks prior to delivery, the newborn had severe pulmonary hypertension and required treatment for 22 days of high doses of inhaled nitric oxide. Another study investigated 180 cases of patients who had reported adverse reactions to diclofenac to the Food and Drug Administration (Banks et al., Hepatology 22(3): 820-827 (1995)). Of the 180 reported cases, the most common symptom was jaundice (75% of the symptomatic patients). Liver sections were taken and analyzed, and hepatic injury was apparent one month after drug treatment. An additional report showed that a patient developed severe hepatitis five weeks after beginning diclofenac treatment for osteoarthritis (Bhogaraju et al., South Med J 92(7): 711-713 (1999)). Within a few months following the cessation of diclofenac treatment there was complete restoration of liver functions. In one study on diclofenac-treated Wistar rats (Ebong et al., Afr J Med Sci 27(3-4): 243-246 (1998)), diclofenac treatment induced an increase in serum chemistry levels of alanine aminotransferase, aspartate aminotransferase, methaemoglobin, and total and conjugated bilirubin. Additionally, diclofenac enhanced the activity of alkaline phosphatase and 5′nucleotidase. Another study showed that humans given diclofenac had elevated levels of hepatic transaminases and serum creatine when compared to the control group (McKenna et al., Scand J Rheumatol 30(1): 11-18 (2001)). The anti-hypertensive drug AY-25329 (Wyeth-Ayerst) exhibits nephrotoxicity in the proximal, and possibly distal, tubules of the kidney. Although no data on its effects in humans is publicly available, the inventors of the present invention have observed minor changes associated with liver necrosis in rats. Specifically, increased mitosis rates and decreased glycogen levels were seen in all rats examined, indicating some measure of toxic response. Bicalutamide is a non-steroidal anti-androgen that is a mixed-oxidase inducer. This drug causes liver enlargement. Its effects on the liver have been described in studies on rats and dogs, but have not been demonstrated in humans (Iswaran et al., J Toxicol Sci 22(2):75-88 (1997). Studies by the instant inventors have shown an increase in mitosis rates and a minor degree of hepatocellular hypertrophy in the rat. Clofibrate is a peroxisome proliferator that has also been reported to cause non-genotoxic carcinogenicity in rodent livers (Qu et al., Free Radic Biol Med 31 (5):659-969 (2001); Mochizuki et al., Carcinogenesis 3(9):1027 (1982)). This compound is also known to cause liver enlargement (IARC Geneva: World Health Organization, International Agency for Research on Cancer, 1972-Present, p.V24 45 (1980); Fort et al., Toxicology 28(4):305 (1983)). Studies by the present inventors show early increases in AST and ALT levels followed by dose-dependent hepatocellular alterations and increased mitotic activity. Diflunisal is a non-steroidal anti-inflammatory drug that is thought to exhibit toxicity in humans, but not in rodent animal models. Its effects in rat hepatocytes, however, have been documented (Masubuchi et al., J Pharmacol Exp Ther 287(1):208-213 (1998)). In addition, as a class of compounds, NSAIDS are infamous for their toxic effects (Johnson et al., Drugs Aging 1(2):130-143 (1991)). Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) is known to cause hepatocellular carcinogenicity in rodent animal models (NTP; Bioassay of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, p.v, DHHS Publication No (NIH) 80-1765 (1980)), although this effect is known to be specific to certain sensitive strains (Viluksela et al., Cancer Res 60(24):6911-6920 (2000). This chemical also causes liver cancers in humans (IARC Geneva: World Health Organization, International Agency for Research on Cancer, 1972-Present, p. 69 342 (1997)). Hydrazine (Isoniazid) is a known liver carcinogen in the rodent and is also thought to cause steatosis (Waterfield et al., Arch Toxicol 67(4):244-254 (1993); American Conference of Governmental Industrial Hygienists, Inc., 6th ed., vols. I-III, p. 761, ACGIH, Cincinnati, Ohio, 1991). It may be carcinogenic in humans as well, but the data in humans is not yet sufficient to be conclusive. Hydarzine's toxicity has also been documented in rat primary cultured hepatocytes (Ghatineh et al., Toxicology in Vitro 8(3):393-399 (1994)). Lipopolysaccharides are known endotoxins that induce inflammation (hepatitis) in the rat liver (Nolan, Hepatology 1(5):458-65 (1981)). They have also been shown to induce cytotoxicity in primary cultured rat hepatocytes and in Kupffer cells (Hartung et al., Biochem Pharmacol 42(5):1129-1135 (1991)). Phenobarbital is a barbiturate that is a known Cytochrome P450 inducer. Chronic dosing of this compound is known to induce non-genotoxic tumorigenesis (Whysner et al., Pharmacol Ther 71(1-2):153-191 (1996)). Tacrine, a strong acetylcholinesterase (AChE) inhibitor, is used in the treatment of mild to moderate cases Alzheimer's dimentias. The effect seen in patients is a reversal of the cognitive and functional decline, but the drug does not appear to change the neurodegenerative process ( Goodman & Gilman's The Pharmacological Basis of Therapeutics, 9 th ed. , p. 174, Hardman et al., eds., McGraw Hill, New York, 1996). Hepatotoxicty caused by tacrine is typically reversible, although cases of severe hepatotoxicity have been seen. In one case study, a 75-year-old woman suffering from . Alzheimer's disease had been administered tacrine for a period of 14 months (Blackard et al. J Clin Gastroenterol 26:57-59 (1998)). The woman developed progressive jaundice, followed by hepatic failure and death. Preclinical studies failed to detect adverse hepatic events (Viau et al., Drug Chem Toxicol 16: 227-239 (1993)). While hepatotoxicity has been found in humans, in vivo rat studies have not shown a correlation between tacrine and hepatotoxicity, and the mechanism of action is not completely understood. In one in vitro study, tacrine displayed cytotoxicity to human hepatoma cell lines and primary rat hepatocytes (Viau et al., supra). Another in vitro study compared the reaction of human and rat liver microsomal preparations to tacrine (Woolf et al., Drug Metab Dispos 21:874-882 (1993)). The study showed that the two species reacted differently to the drug, suggesting that the rat may not be the best model for monitoring tacrine-induced elevations in liver marker enzymes. While tacrine does not reveal classic signs of hepatotoxicity in rats, gene expression changes due to tacrine administration can be used to predict that the drug will be a liver toxin in humans. This suggests that toxicogenomics might be able to detect drugs that prove to be toxic in the clinic, even when classical but more crude measures in preclinical screening fail to detect toxicity. Valproate (valproic acid) is an anti-convulsant that causes fatty liver and necrosis in both humans and rodents (Eadie, Med Toxicol Adverse Drug Exp 3(2):85-106 (1988); Lewis, Hepatology 2(6):870-873, (1982)). This compound is also known to cause severe developmental defects (Briggs et al., A Reference Guide to Fetal and Neonatal Risk. Drugs in Pregnancy and Lactation, 4 th ed ., p. 869, Williams & Wilkins, Baltimore, Md. 1994). Zileuton is thought to cause general inflammation (hepatitis) in the liver of humans. Its effects in rodents are minimal, with some observed cytochrome P450 induction and weak peroxisome proliferation (Rodrigues et al., Toxicol Appl Pharmacol 137(2): 193-201 (1996)). Acyclovir (9-[(2-hydroxyethyl)methyl]guanine, Zovirax®), an anti-viral guanosine analogue, is used to treat herpes simplex virus (HSV), varicella zoster virus (VZV) and Epstein-Barr virus (EBV) infections. It is phosphorylated by virally encoded thymidine kinase (TK) and converted to its activated di- and triphosphate forms by other kinases. Viral polymerases preferentially incorporate acyclovir, over natural bases, into viral DNA, but, because acyclovir is incorporated as a monophosphate, chain elongation is terminated. Acyclovir is not effective against viruses or viral mutants that lack TK (Fields Virology 3d ed., Fields et al., eds., pp. 436-440, Lippincott-Raven Publishers, Philadelphia, 1996; Cecil Textbook of Medicine, 20 th ed., part XII, p. 1742, J. C. Bennett and F. Plum Eds., W. B. Saunders Co., Philadelphia, 1996). The pharmacokinetics of acyclovir show that it has a half-life of about three hours and that most of it is excreted in the urine largely unchanged (Brigden et al., “The clinical pharmacology of acyclovir and its prodrugs,” Scand J Infect Dis Suppl 47:33-39, 1985). The most frequent adverse effect of acyclovir treatment is damage to various parts of the kidney, particularly the renal tubules, where the precipitation of crystals of acyclovir can occur (Fogazzi, “Crystalluria: a neglected aspect of urinary sediment analysis,” Nephrol Dial Transplant 11(2):379-387, 1996). Although acyclovir is primarily a renal toxin, it has been shown to induce liver inflammation (hepatitis) ( Physicians' Desk Reference, 56 th ed. , p. 1707, Medical Economics Co. Inc., Montvale, N.J., 2002). Findings of hepatotoxicity in animals have not yet been published. Toxicity Prediction and Modeling The genes and gene expression information, as well as the portfolios and subsets of the genes provided in Tables 1-3, may be used to predict at least one toxic effect, including the hepatotoxicity of a test or unknown compound. As used, herein, at least one toxic effect includes, but is not limited to, a detrimental change in the physiological status of a cell or organism. The response may be, but is not required to be, associated with a particular pathology, such as tissue necrosis. Accordingly, the toxic effect includes effects at the molecular and cellular level. Hepatotoxicity is an effect as used herein and includes but is not limited to the pathologies of liver necrosis, hepatitis, fatty liver and protein adduct formation. As used herein, a gene expression profile comprises any quantitative representation of the expression of at least one mRNA species in a cell sample or population and includes profiles made by various methods such as differential display, PCR, hybridization analysis, etc. In general, assays to predict the toxicity or hepatotoxicity of a test agent (or compound or multi-component composition) comprise the steps of exposing a cell population to the test compound, assaying or measuring the level of relative or absolute gene expression of one or more of the genes in Tables 1-3 and comparing the identified expression level(s) to the expression levels disclosed in the Tables and database(s) disclosed herein. Assays may include the measurement of the expression levels of about 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 50, 75, 100 or more genes from Tables 1-3. In the methods of the invention, the gene expression level for a gene or genes induced by the test agent, compound or compositions may be comparable to the levels found in the Tables or databases disclosed herein if the expression level varies within a factor of about 2, about 1.5 or about 1.0 fold. In some cases, the expression levels are comparable if the agent induces a change in the expression of a gene in the same direction (e.g., up or down) as a reference toxin. The cell population that is exposed to the test agent, compound or composition may be exposed in vitro or in vivo. For instance, cultured or freshly isolated hepatocytes, in particular rat hepatocytes, may be exposed to the agent under standard laboratory and cell culture conditions. In another assay format, in vivo exposure may be accomplished by administration of the agent to a living animal, for instance a laboratory rat. Procedures for designing and conducting toxicity tests in in vitro and in vivo systems are well known, and are described in many texts on the subject, such as Loomis et al., Loomis's Esstentials of Toxicology, 4 th Ed ., Academic Press, New York, 1996; Echobichon, The Basics of Toxicity Testing , CRC Press, Boca Raton, 1992; Frazier, editor, In Vitro Toxicity Testing , Marcel Dekker, New York, 1992; and the like. In in vitro toxicity testing, two groups of test organisms are usually employed: One group serves as a control and the other group receives the test compound in a single dose (for acute toxicity tests) or a regimen of doses (for prolonged or chronic toxicity tests). Because, in some cases, the extraction of tissue as called for in the methods of the invention requires sacrificing the test animal, both the control group and the group receiving compound must be large enough to permit removal of animals for sampling tissues, if it is desired to observe the dynamics of gene expression through the duration of an experiment. In setting up a toxicity study, extensive guidance is provided in the literature for selecting the appropriate test organism for the compound being tested, route of administration. dose ranges, and the like. Water or physiological saline (0.9% NaCl in water) is the solute of choice for the test compound since these solvents permit administration by a variety of routes. When this is not possible because of solubility limitations, vegetable oils such as corn oil or organic solvents such as propylene glycol may be used. Regardless of the route of administration, the volume required to administer a given dose is limited by the size of the animal that is used. It is desirable to keep the volume of each dose uniform within and between groups of animals. When rats or mice are used, the volume administered by the oral route generally should not exceed about 0.005 ml per gram of animal. Even when aqueous or physiological saline solutions are used for parenteral injection the volumes that are tolerated are limited, although such solutions are ordinarily thought of as being innocuous. The intravenous LD 50 of distilled water in the mouse is approximately 0.044 ml per gram and that of isotonic saline is 0.068 ml per gram of mouse. In some instances, the route of administration to the test animal should be the same as, or as similar as possible to, the route of administration of the compound to man for therapeutic purposes. When a compound is to be administered by inhalation, special techniques for generating test atmospheres are necessary. The methods usually involve aerosolization or nebulization of fluids containing the compound. If the agent to be tested is a fluid that has an appreciable vapor pressure, it may be administered by passing air through the solution under controlled temperature conditions. Under these conditions, dose is estimated from the volume of air inhaled per unit time, the temperature of the solution, and the vapor pressure of the agent involved. Gases are metered from reservoirs. When particles of a solution are to be administered, unless the particle size is less than about 2 μm the particles will not reach the terminal alveolar sacs in the lungs. A variety of apparatuses and chambers are available to perform studies for detecting effects of irritant or other toxic endpoints when they are administered by inhalation. The preferred method of administering an agent to animals is via the oral route, either by intubation or by incorporating the agent in the feed. When the agent is exposed to cells in vitro or in cell culture, the cell population to be exposed to the agent may be divided into two or more subpopulations, for instance, by dividing the population into two or more identical aliquots. In some preferred embodiments of the methods of the invention, the cells to be exposed to the agent are derived from liver tissue. For instance, cultured or freshly isolated rat hepatocytes may be used. The methods of the invention may be used generally to predict at least one toxic response, and, as described in the Examples, may be used to predict the likelihood that a compound or test agent will induce various specific liver pathologies, such as liver necrosis, fatty liver disease, protein adduct formation, hepatitis, or other pathologies associated with at least one of the toxins herein described. The methods of the invention may also be used to determine the similarity of a toxic response to one or more individual compounds. In addition, the methods of the invention may be used to predict or elucidate the potential cellular pathways influenced, induced or modulated by the compound or test agent due to the similarity of the expression profile compared to the profile induced by a known toxin (see Tables 3A-3DD). Diagnostic Uses for the Toxicity Markers As described above, the genes and gene expression information or portfolios of the genes with their expression information as provided in Tables 1-3 may be used as diagnostic markers for the prediction or identification of the physiological state of tissue or cell sample that has been exposed to a compound or to identify or predict the toxic effects of a compound or agent. For instance, a tissue sample such as a sample of peripheral blood cells or some other easily obtainable tissue sample may be assayed by any of the methods described above, and the expression levels from a gene or genes from Tables 1-3 may be compared to the expression levels found in tissues or cells exposed to the toxins described herein. These methods may result in the diagnosis of a physiological state in the cell or may be used to identify the potential toxicity of a compound, for instance a new or unknown compound or agent. The comparison of expression data, as well as available sequence or other information may be done by researcher or diagnostician or may be done with the aid of a computer and databases as described below. In another format, the levels of a gene(s) of Tables 1-3, its encoded protein(s), or any metabolite produced by the encoded protein may be monitored or detected in a sample, such as a bodily tissue or fluid sample to identify or diagnose a physiological state of an organism. Such samples may include any tissue or fluid sample, including urine, blood and easily obtainable cells such as peripheral lymphocytes. Use of the Markers for Monitoring Toxicity Progression As described above, the genes and gene expression information provided in Tables 1-3 may also be used as markers for the monitoring of toxicity progression, such as that found after initial exposure to a drug, drug candidate, toxin, pollutant, etc. For instance, a tissue or cell sample may be assayed by any of the methods described above, and the expression levels from a gene or genes from Tables 1-3 may be compared to the expression levels found in tissue or cells exposed to the hepatotoxins described herein. The comparison of the expression data, as well as available sequence or other information may be done by researcher or diagnostician or may be done with the aid of a computer and databases. Use of the Toxicity Markers for Drug Screening According to the present invention, the genes identified in Tables 1-3 may be used as markers or drug targets to evaluate the effects of a candidate drug, chemical compound or other agent on a cell or tissue sample. The genes may also be used as drug targets to screen for agents that modulate their expression and/or activity. In various formats, a candidate drug or agent can be screened for the ability to simulate the transcription or expression of a given marker or markers or to down-regulate or counteract the transcription or expression of a marker or markers. According to the present invention, one can also compare the specificity of a drug's effects by looking at the number of markers which the drug induces and comparing them. More specific drugs will have less transcriptional targets. Similar sets of markers identified for two drugs may indicate a similarity of effects. Assays to monitor the expression of a marker or markers as defined in Tables 1-3 may utilize any available means of monitoring for changes in the expression level of the nucleic acids of the invention. As used herein, an agent is said to modulate the expression of a nucleic acid of the invention if it is capable of up- or down-regulating expression of the nucleic acid in a cell. In one assay format, gene chips containing probes to one, two or more genes from Tables 1-3 may be used to directly monitor or detect changes in gene expression in the treated or exposed cell. Cell lines, tissues or other samples are first exposed to a test agent and in some instances, a known toxin, and the detected expression levels of one or more, or preferably 2 or more of the genes of Tables 1-3 are compared to the expression levels of those same genes exposed to a known toxin alone. Compounds that modulate the expression patterns of the known toxin(s) would be expected to modulate potential toxic physiological effects in vivo. The genes in Tables 1-3 are particularly appropriate marks in these assays as they are differentially expressed in cells upon exposure to a known hepatotoxin. In another format, cell lines that contain reporter gene fusions between the open reading frame and/or the transcriptional regulatory regions of a gene in Tables 1-3 and any assayable fusion partner may be prepared. Numerous assayable fusion partners are known and readily available including the firefly luciferase gene and the gene encoding chloramphenicol acetyltransferase (Alam et al., Anal Biochem 188:245-254 (1990)). Cell lines containing the reporter gene fusions are then exposed to the agent to be tested under appropriate conditions and time. Differential expression of the reporter gene between samples exposed to the agent and control samples identifies agents which modulate the expression of the nucleic acid. Additional assay formats may be used to monitor the ability of the agent to modulate the expression of a gene identified in Tables 1-3. For instance, as described above, mRNA expression may be monitored directly by hybridization of probes to the nucleic acids of the invention. Cell lines are exposed to the agent to be tested under appropriate conditions and time and total RNA or mRNA is isolated by standard procedures such those disclosed in Sambrook et al. ( Molecular Cloning: A Laboratory Manual, 2 nd Ed ., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 1989). In another assay format, cells or cell lines are first identified which express the gene products of the invention physiologically. Cell and/or cell lines so identified would be expected to comprise the necessary cellular machinery such that the fidelity of modulation of the transcriptional apparatus is maintained with regard to exogenous contact of agent with appropriate surface transduction mechanisms and/or the cytosolic cascades. Further, such cells or cell lines may be transduced or transfected with an expression vehicle (e.g., a plasmid or viral vector) construct comprising an operable non-translated 5′-promoter containing end of the structural gene encoding the gene products of Tables 1-3 fused to one or more antigenic fragments or other detectable markers, which are peculiar to the instant gene products, wherein said fragments are under the transcriptional control of said promoter and are expressed as polypeptides whose molecular weight can be distinguished from the naturally occurring polypeptides or may further comprise an immunologically distinct or other detectable tag. Such a process is well known in the art (see Sambrook et al., supra). Cells or cell lines transduced or transfected as outlined above are then contacted with agents under appropriate conditions; for example, the agent comprises a pharmaceutically acceptable excipient and is contacted with cells comprised in an aqueous physiological buffer such as phosphate buffered saline (PBS) at physiological pH, Eagles balanced salt solution (BSS) at physiological pH, PBS or BSS comprising serum or conditioned media comprising PBS or BSS and/or serum incubated at 37 C. Said conditions may be modulated as deemed necessary by one of skill in the art. Subsequent to contacting the cells with the agent, said cells are disrupted and the polypeptides of the lysate are fractionated such that a polypeptide fraction is pooled and contacted with an antibody to be further processed by immunological assay (e.g., ELISA, immunoprecipitation or Western blot). The pool of proteins isolated from the agent-contacted sample is then compared with the control samples (no exposure and exposure to a known toxin) where only the excipient is contacted with the cells and an increase or decrease in the immunologically generated signal from the agent-contacted sample compared to the control is used to distinguish the effectiveness and/or toxic effects of the agent. Another embodiment of the present invention provides methods for identifying agents that modulate at least one activity of a protein(s) encoded by the genes in Tables 1-3. Such methods or assays may utilize any means of monitoring or detecting the desired activity. In one format, the relative amounts of a protein (Tables 1-3) between a cell population that has been exposed to the agent to be tested compared to an un-exposed control cell population and a cell population exposed to a known toxin may be assayed. In this format, probes such as specific antibodies are used to monitor the differential expression of the protein in the different cell populations. Cell lines or populations are exposed to the agent to be tested under appropriate conditions and time. Cellular lysates may be prepared from the exposed cell line or population and a control, unexposed cell line or population. The cellular lysates are then analyzed with the probe, such as a specific antibody. Agents that are assayed in the above methods can be randomly selected or rationally selected or designed. As used herein, an agent is said to be randomly selected when the agent is chosen randomly without considering the specific sequences involved in the association of the a protein of the invention alone or with its associated substrates, binding partners, etc. An example of randomly selected agents is the use a chemical library or a peptide combinatorial library, or a growth broth of an organism. As used herein, an agent is said to be rationally selected or designed when the agent is chosen on a nonrandom basis which takes into account the sequence of the target site and/or its conformation in connection with the agent s action. Agents can be rationally selected or rationally designed by utilizing the peptide sequences that make up these sites. For example, a rationally selected peptide agent can be a peptide whose amino acid sequence is identical to or a derivative of any functional consensus site. The agents of the present invention can be, as examples, peptides, small molecules, vitamin derivatives, as well as carbohydrates. Dominant negative proteins, DNAs encoding these proteins, antibodies to these proteins, peptide fragments of these proteins or mimics of these proteins may be introduced into cells to affect function. “Mimic” used herein refers to the modification of a region or several regions of a peptide molecule to provide a structure chemically different from the parent peptide but topographically and functionally similar to the parent peptide (see G. A. Grant in: Molecular Biology and Biotechnology , Meyers, ed., pp. 659-664, VCH Publishers, New York, 1995). A skilled artisan can readily recognize that there is no limit as to the structural nature of the agents of the present invention. Nucleic Acid Assay Formats The genes identified as being differentially expressed upon exposure to a known hepatotoxin (Tables 1-3) may be used in a variety of nucleic acid detection assays to detect or quantititate the expression level of a gene or multiple genes in a given sample. The genes described in Tables 1-3 may also be used in combination with one or more additional genes whose differential expression is associate with toxicity in a cell or tissue. In preferred embodiments, the genes in Tables 1-3 may be combined with one or more of the genes described in prior and related applications 60/222,040, 60/244,880, 60/290,029, 60/290,645, 60/292,336, 60/295,798, 60/297,457, 60/298,884, 60/303,459 and 09/917,800, all of which are incorporated by reference on page 1 of this application. Any assay format to detect gene expression may be used. For example, traditional Northern blotting, dot or slot blot, nuclease protection, primer directed amplification, RT-PCR, semi- or quantitative PCR, branched-chain DNA and differential display methods may be used for detecting gene expression levels. Those methods are useful for some embodiments of the invention. In cases where smaller numbers of genes are detected, amplification based assays may be most efficient. Methods and assays of the invention, however, may be most efficiently designed with hybridization-based methods for detecting the expression of a large number of genes. Any hybridization assay format may be used, including solution-based and solid support-based assay formats. Solid supports containing oligonucleotide probes for differentially expressed genes of the invention can be filters, polyvinyl chloride dishes, particles, beads, microparticles or silicon or glass based chips, etc. Such chips, wafers and hybridization methods are widely available, for example, those disclosed by Beattie (WO 95/11755). Any solid surface to which oligonucleotides can be bound, either directly or indirectly, either covalently or non-covalently, can be used. A preferred solid support is a high density array or DNA chip. These contain a particular oligonucleotide probe in a predetermined location on the array. Each predetermined location may contain more than one molecule of the probe, but each molecule within the predetermined location has an identical sequence. Such predetermined locations are termed features. There may be, for example, from 2, 10, 100, 1000 to 10,000, 100,000 or 400,000 or more of such features on a single solid support. The solid support, or the area within which the probes are attached may be on the order of about a square centimeter. Probes corresponding to the genes of Tables 1-3 or from the related applications described above may be attached to single or multiple solid support structures, e.g., the probes may be attached to a single chip or to multiple chips to comprise a chip set. Oligonucleotide probe arrays for expression monitoring can be made and used according to any techniques known in the art (see for example, Lockhart et al., Nat Biotechnol 14:1675-1680 (1996); McGall et al., Proc Nat Acad Sci USA 93:13555-13460 (1996)). Such probe arrays may contain at least two or more oligonucleotides that are complementary to or hybridize to two or more of the genes described in Tables 1-3. For instance, such arrays may contain oligonucleotides that are complementary or hybridize to at least 2, 3, 4, 5, 6, 7, 8, 9, 10, 20, 30, 50, 70, 100 or more the genes described herein. Preferred arrays contain all or nearly all of the genes listed in Tables 1-3, or individually, the gene sets of Tables 3A-3DD. In a preferred embodiment, arrays are constructed that contain oligonucleotides to detect all or nearly all of the genes in any one of or all of Tables 1-3 on a single solid support substrate, such as a chip. The sequences of the expression marker genes of Tables 1-3 are in the public databases. Table 1 provides the GenBank Accession Number for each of the sequences. The sequences of the genes in GenBank are expressly herein incorporated by reference in their entirety as of the filing date of this application, as are related sequences, for instance, sequences from the same gene of different lengths, variant sequences, polymorphic sequences, genomic sequences of the genes and related sequences from different species, including the human counterparts, where appropriate. These sequences may be used in the methods of the invention or may be used to produce the probes and arrays of the invention. In some embodiments, the genes in Tables 1-3 that correspond to the genes or fragments previously associated with a toxic response may be excluded from the Tables. As described above, in addition to the sequences of the GenBank Accessions Numbers disclosed in the Tables 1-3, sequences such as naturally occurring variant or polymorphic sequences may be used in the methods and compositions of the invention. For instance, expression levels of various allelic or homologous forms of a gene disclosed in the Tables 1-3 may be assayed. Any and all nucleotide variations that do not alter the functional activity of a gene listed in the Tables 1-3, including all naturally occurring allelic variants of the genes herein disclosed, may be used in the methods and to make the compositions (e.g., arrays) of the invention. Probes based on the sequences of the genes described above may be prepared by any commonly available method. Oligonucleotide probes for screening or assaying a tissue or cell sample are preferably of sufficient length to specifically hybridize only to appropriate, complementary genes or transcripts. Typically the oligonucleotide probes will be at least about 10, 12, 14, 16, 18, 20 or 25 nucleotides in length. In some cases, longer probes of at least 30, 40, or 50 nucleotides will be desirable. As used herein, oligonucleotide sequences that are complementary to one or more of the genes described in Tables 1-3 refer to oligonucleotides that are capable of hybridizing under stringent conditions to at least part of the nucleotide sequences of said genes. Such hybridizable oligonucleotides will typically exhibit at least about 75% sequence identity at the nucleotide level to said genes, preferably about 80% or 85% sequence identity or more preferably about 90% or 95% or more sequence identity to said genes. “Bind(s) substantially” refers to complementary hybridization between a probe nucleic acid and a target nucleic acid and embraces minor mismatches that can be accommodated by reducing the stringency of the hybridization media to achieve the desired detection of the target polynucleotide sequence. The terms “background” or “background signal intensity” refer to hybridization signals resulting from non-specific binding, or other interactions, between the labeled target nucleic acids and components of the oligonucleotide array (e.g., the oligonucleotide probes, control probes, the array substrate, etc.). Background signals may also be produced by intrinsic fluorescence of the array components themselves. A single background signal can be calculated for the entire array, or a different background signal may be calculated for each target nucleic acid. In a preferred embodiment, background is calculated as the average hybridization signal intensity for the lowest 5% to 10% of the probes in the array, or, where a different background signal is calculated for each target gene, for the lowest 5% to 10% of the probes for each gene. Of course, one of skill in the art will appreciate that where the probes to a particular gene hybridize well and thus appear to be specifically binding to a target sequence, they should not be used in a background signal calculation. Alternatively, background may be calculated as the average hybridization signal intensity produced by hybridization to probes that are not complementary to any sequence found in the sample (e.g. probes directed to nucleic acids of the opposite sense or to genes not found in the sample such as bacterial genes where the sample is mammalian nucleic acids). Background can also be calculated as the average signal intensity produced by regions of the array that lack any probes at all. The phrase “hybridizing specifically to” refers to the binding, duplexing, or hybridizing of a molecule substantially to or only to a particular nucleotide sequence or sequences under stringent conditions when that sequence is present in a complex mixture (e.g., total cellular) DNA or RNA. Assays and methods of the invention may utilize available formats to simultaneously screen at least about 100, preferably about 1000, more preferably about 10,000 and most preferably about 1,000,000 different nucleic acid hybridizations. As used herein a “probe” is defined as a nucleic acid, capable of binding to a target nucleic acid of complementary sequence through one or more types of chemical bonds, usually through complementary base pairing, usually through hydrogen bond formation. As used herein, a probe may include natural (i.e., A, G, U, C, or T) or modified bases (7-deazaguanosine, inosine, etc.). In addition, the bases in probes may be joined by a linkage other than a phosphodiester bond, so long as it does not interfere with hybridization. Thus, probes may be peptide nucleic acids in which the constituent bases are joined by peptide bonds rather than phosphodiester linkages. The term “perfect match probe” refers to a probe that has a sequence that is perfectly complementary to a particular target sequence. The test probe is typically perfectly complementary to a portion (subsequence) of the target sequence. The perfect match (PM) probe can be a “test probe”, a “normalization control” probe, an expression level control probe and the like. A perfect match control or perfect match probe is, however, distinguished from a “mismatch control” or “mismatch probe.” The terms “mismatch control” or “mismatch probe” refer to a probe whose sequence is deliberately selected not to be perfectly complementary to a particular target sequence. For each mismatch (MM) control in a high-density array there typically exists a corresponding perfect match (PM) probe that is perfectly complementary to the same particular target sequence. The mismatch may comprise one or more bases. While the mismatch(s) may be located anywhere in the mismatch probe, terminal mismatches are less desirable as a terminal mismatch is less likely to prevent hybridization of the target sequence. In a particularly preferred embodiment, the mismatch is located at or near the center of the probe such that the mismatch is most likely to destabilize the duplex with the target sequence under the test hybridization conditions. The term “stringent conditions” refers to conditions under which a probe will hybridize to its target subsequence, but with only insubstantial hybridization to other sequences or to other sequences such that the difference may be identified. Stringent conditions are sequence-dependent and will be different in different circumstances. Longer sequences hybridize specifically at higher temperatures. Generally, stringent conditions are selected to be about 5° C. lower than the thermal melting point (Tm) for the specific sequence at a defined ionic strength and pH. Typically, stringent conditions will be those in which the salt concentration is at least about 0.01 to 1.0 M Na + ion concentration (or other salts) at pH 7.0 to 8.3 and the temperature is at least about 30° C. for short probes (e.g., 10 to 50 nucleotides). Stringent conditions may also be achieved with the addition of destabilizing agents such as formamide. The “percentage of sequence identity” or “sequence identity” is determined by comparing two optimally aligned sequences or subsequences over a comparison window or span, wherein the portion of the polynucleotide sequence in the comparison window may optionally comprise additions or deletions (i.e., gaps) as compared to the reference sequence (which does not comprise additions or deletions) for optimal alignment of the two sequences. The percentage is calculated by determining the number of positions at which the identical submit (e.g. nucleic acid base or amino acid residue) occurs in both sequences to yield the number of matched positions, dividing the number of matched positions by the total number of positions in the window of comparison and multiplying the result by 100 to yield the percentage of sequence identity. Percentage sequence identity when calculated using the programs GAP or BESTFIT (see below) is calculated using default gap weights. Probe Design One of skill in the art will appreciate that an enormous number of array designs are suitable for the practice of this invention. The high density array will typically include a number of test probes that specifically hybridize to the sequences of interest. Probes may be produced from any region of the genes identified in the Tables and the attached representative sequence listing. In instances where the gene reference in the Tables is an EST, probes may be designed from that sequence or from other regions of the corresponding full-length transcript that may be available in any of the sequence databases, such as those herein described. See WO 99/32660 for methods of producing probes for a given gene or genes. In addition, any available software may be used to produce specific probe sequences, including, for instance, software available from Molecular Biology Insights, Olympus Optical Co. and Biosoft International. In a preferred embodiment, the array will also include one or more control probes. High density array chips of the invention include “test probes.” Test probes may be oligonucleotides that range from about 5 to about 500, or about 7 to about 50 nucleotides, more preferably from about 10 to about 40 nucleotides and most preferably from about 15 to about 35 nucleotides in length. In other particularly preferred embodiments, the probes are 20 or 25 nucleotides in length. In another preferred embodiment, test probes are double or single strand DNA sequences. DNA sequences are isolated or cloned from natural sources or amplified from natural sources using native nucleic acid as templates. These probes have sequences complementary to particular subsequences of the genes whose expression they are designed to detect. Thus, the test probes are capable of specifically hybridizing to the target nucleic acid they are to detect. In addition to test probes that bind the target nucleic acid(s) of interest, the high density array can contain a number of control probes. The control probes may fall into three categories referred to herein as 1) normalization controls; 2) expression level controls; and 3) mismatch controls. Normalization controls are oligonucleotide or other nucleic acid probes that are complementary to labeled reference oligonucleotides or other nucleic acid sequences that are added to the nucleic acid sample to be screened. The signals obtained from the normalization controls after hybridization provide a control for variations in hybridization conditions, label intensity, “reading” efficiency and other factors that may cause the signal of a perfect hybridization to vary between arrays. In a preferred embodiment, signals (e.g., fluorescence intensity) read from all other probes in the array are divided by the signal (e.g., fluorescence intensity) from the control probes thereby normalizing the measurements. Virtually any probe may serve as a normalization control. However, it is recognized that hybridization efficiency varies with base composition and probe length. Preferred normalization probes are selected to reflect the average length of the other probes present in the array, however, they can be selected to cover a range of lengths. The normalization control(s) can also be selected to reflect the (average) base composition of the other probes in the array, however in a preferred embodiment, only one or a few probes are used and they are selected such that they hybridize well (i.e., no secondary structure) and do not match any target-specific probes. Expression level controls are probes that hybridize specifically with constitutively expressed genes in the biological sample. Virtually any constitutively expressed gene provides a suitable target for expression level controls. Typically expression level control probes have sequences complementary to subsequences of constitutively expressed “housekeeping genes” including, but not limited to the actin gene, the transferrin receptor gene, the GAPDH gene, and the like. Mismatch controls may also be provided for the probes to the target genes, for expression level controls or for normalization controls. Mismatch controls are oligonucleotide probes or other nucleic acid probes identical to their corresponding test or control probes except for the presence of one or more mismatched bases. A mismatched base is a base selected so that it is not complementary to the corresponding base in the target sequence to which the probe would otherwise specifically hybridize. One or more mismatches are selected such that under appropriate hybridization conditions (e.g., stringent conditions) the test or control probe would be expected to hybridize with its target sequence, but the mismatch probe would not hybridize (or would hybridize to a significantly lesser extent) Preferred mismatch probes contain a central mismatch. Thus, for example, where a probe is a 20 mer, a corresponding mismatch probe will have the identical sequence except for a single base mismatch (e.g., substituting a G, a C or a T for an A) at any of positions 6 through 14 (the central mismatch). Mismatch probes thus provide a control for non-specific binding or cross hybridization to a nucleic acid in the sample other than the target to which the probe is directed. For example, if the target is present the perfect match probes should be consistently brighter than the mismatch probes. In addition, if all central mismatches are present, the mismatch probes can be used to detect a mutation, for instance, a mutation of a gene in the accompanying Tables 1-3. The difference in intensity between the perfect match and the mismatch probe provides a good measure of the concentration of the hybridized material. Nucleic Acid Samples Cell or tissue samples may be exposed to the test agent in vitro or in vivo. When cultured cells or tissues are used, appropriate mammalian liver extracts may also be added with the test agent to evaluate agents that may require biotransformation to exhibit toxicity. In a preferred format, primary isolates of animal or human hepatocytes which already express the appropriate complement of drug-metabolizing enzymes may be exposed to the test agent without the addition of mammalian liver extracts. The genes which are assayed according to the present invention are typically in the form of mRNA or reverse transcribed mRNA. The genes may be cloned or not. The genes may be amplified or not. The cloning and/or amplification do not appear to bias the representation of genes within a population. In some assays, it may be preferable, however, to use polyA+ RNA as a source, as it can be used with less processing steps. As is apparent to one of ordinary skill in the art, nucleic acid samples used in the methods and assays of the invention may be prepared by any available method or process. Methods of isolating total mRNA are well known to those of skill in the art. For example, methods of isolation and purification of nucleic acids are described in detail in Chapter 3 of Laboratory Techniques in Biochemistry and Molecular Biology, Vol. 24, Hybridization With Nucleic Acid Probes: Theory and Nucleic Acid Probes, P. Tijssen, Ed., Elsevier Press, New York, 1993. Such samples include RNA samples, but also include cDNA synthesized from a mRNA sample isolated from a cell or tissue of interest. Such samples also include DNA amplified from the cDNA, and RNA transcribed from the amplified DNA. One of skill in the art would appreciate that it is desirable to inhibit or destroy RNase present in homogenates before homogenates are used. Biological samples may be of any biological tissue or fluid or cells from any organism as well as cells raised in vitro, such as cell lines and tissue culture cells. Frequently the sample will be a tissue or cell sample that has been exposed to a compound, agent, drug, pharmaceutical composition, potential environmental pollutant or other composition. In some formats, the sample will be a “clinical sample” which is a sample derived from a patient. Typical clinical samples include, but are not limited to, sputum, blood, blood-cells (e.g., white cells), tissue or fine needle biopsy samples, urine, peritoneal fluid, and pleural fluid, or cells therefrom. Biological samples may also include sections of tissues, such as frozen sections or formalin fixed sections taken for histological purposes. Forming High Density Arrays Methods of forming high density arrays of oligonucleotides with a minimal number of synthetic steps are known. The oligonucleotide analogue array can be synthesized on a single or on multiple solid substrates by a variety of methods, including, but not limited to, light-directed chemical coupling, and mechanically directed coupling (see Pirrung, U.S. Pat. No. 5,143,854). In brief, the light-directed combinatorial synthesis of oligonucleotide arrays on a glass surface proceeds using automated phosphoramidite chemistry and chip masking techniques. In one specific implementation, a glass surface is derivatized with a silane reagent containing a functional group, e.g., a hydroxyl or amine group blocked by a photolabile protecting group. Photolysis through a photolithogaphic mask is used selectively to expose functional groups which are then ready to react with incoming 5′ photoprotected nucleoside phosphoramidites. The phosphoramidites react only with those sites which are illuminated (and thus exposed by removal of the photolabile blocking group). Thus, the phosphoramidites only add to those areas selectively exposed from the preceding step. These steps are repeated until the desired array of sequences have been synthesized on the solid surface. Combinatorial synthesis of different oligonucleotide analogues at different locations on the array is determined by the pattern of illumination during synthesis and the order of addition of coupling reagents. In addition to the foregoing, additional methods which can be used to generate an array of oligonucleotides on a single substrate are described in PCT Publication Nos. WO 93/09668 and WO 01/23614. High density nucleic acid arrays can also be fabricated by depositing pre-made or natural nucleic acids in predetermined positions. Synthesized or natural nucleic acids are deposited on specific locations of a substrate by light directed targeting and oligonucleotide directed targeting. Another embodiment uses a dispenser that moves from region to region to deposit nucleic acids in specific spots. Hybridization Nucleic acid hybridization simply involves contacting a probe and target nucleic acid under conditions where the probe and its complementary target can form stable hybrid duplexes through complementary base pairing. See WO 99/32660. The nucleic acids that do not form hybrid duplexes are then washed away leaving the hybridized nucleic acids to be detected, typically through detection of an attached detectable label. It is generally recognized that nucleic acids are denatured by increasing the temperature or decreasing the salt concentration of the buffer containing the nucleic acids. Under low stringency conditions (e.g., low temperature and/or high salt) hybrid duplexes (e.g., DNA:DNA, RNA:RNA, or RNA:DNA) will form even where the annealed sequences are not perfectly complementary. Thus, specificity of hybridization is reduced at lower stringency. Conversely, at higher stringency (e.g., higher temperature or lower salt) successful hybridization tolerates fewer mismatches. One of skill in the art will appreciate that hybridization conditions may be selected to provide any degree of stringency. In a preferred embodiment, hybridization is performed at low stringency, in this case in 6× SSPET at 37° C. (0.005% Triton X-100), to ensure hybridization and then subsequent washes are performed at higher stringency (e.g., I× SSPET at 37° C.) to eliminate mismatched hybrid duplexes. Successive washes may be performed at increasingly higher stringency (e.g., down to as low as 0.25× SSPET at 37° C. to 50° C.) until a desired level of hybridization specificity is obtained. Stringency can also be increased by addition of agents such as formamide. Hybridization specificity may be evaluated by comparison of hybridization to the test probes with hybridization to the various controls that can be present (e.g., expression level control, normalization control, mismatch controls, etc.). In general, there is a tradeoff between hybridization specificity (stringency) and signal intensity. Thus, in a preferred embodiment, the wash is performed at the highest stringency that produces consistent results and that provides a signal intensity greater than approximately 10% of the background intensity. Thus, in a preferred embodiment, the hybridized array may be washed at successively higher stringency solutions and read between each wash. Analysis of the data sets thus produced will reveal a wash stringency above which the hybridization pattern is not appreciably altered and which provides adequate signal for the particular oligonucleotide probes of interest. Signal Detection The hybridized nucleic acids are typically detected by detecting one or more labels attached to the sample nucleic acids. The labels may be incorporated by any of a number of means well known to those of skill in the art. See WO 99/32660. Databases The present invention includes relational databases containing sequence information, for instance, for the genes of Tables 1-3, as well as gene expression information from tissue or cells exposed to various standard toxins, such as those herein described (see Tables 3A-3DD). Databases may also contain information associated with a given sequence or tissue sample such as descriptive information about the gene associated with the sequence information (see Table 1), or descriptive information concerning the clinical status of the tissue sample, or the animal from which the sample was derived. The database may be designed to include different parts, for instance a sequence database and a gene expression database. Methods for the configuration and construction of such databases and computer-readable media to which such databases are saved are widely available, for instance, see U.S. Pat. No. 5,953,727, which is herein incorporated by reference in its entirety. The databases of the invention may be linked to an outside or external database such as GenBank; KEGG; SPAD; HUGO; Swiss-Prot; Prosite; OMIM; GDB; and GeneCard. In a preferred embodiment, as described in Tables 1-3, the external database is GenBank and the associated databases maintained by the National Center for Biotechnology Information (NCBI). Any appropriate computer platform, user interface, etc. may be used to perform the necessary comparisons between sequence information, gene expression information and any other information in the database or information provided as an input. For example, a large number of computer workstations are available from a variety of manufacturers, such has those available from Silicon Graphics. Client/server environments, database servers and networks are also widely available and appropriate platforms for the databases of the invention. The databases of the invention may be used to produce, among other things, electronic Northerns that allow the user to determine the cell type or tissue in which a given gene is expressed and to allow determination of the abundance or expression level of a given gene in a particular tissue or cell. The databases of the invention may also be used to present information identifying the expression level in a tissue or cell of a set of genes comprising one or more of the genes in Tables 1-3, comprising the step of comparing the expression level of at least one gene in Tables 1-3 in a cell or tissue exposed to a test agent to the level of expression of the gene in the database. Such methods may be used to predict the toxic potential of a given compound by comparing the level of expression of a gene or genes in Tables 1-3 from a tissue or cell sample exposed to the test agent to the expression levels found in a control tissue or cell samples exposed to a standard toxin or hepatotoxin such as those herein described. Such methods may also be used in the drug or agent screening assays as described herein. Kits The invention further includes kits combining, in different combinations, high-density oligonucleotide arrays, reagents for use with the arrays, protein reagents encoded by the genes of the Tables, signal detection and array-processing instruments, gene expression databases and analysis and database management software described above. The kits may be used, for example, to predict or model the toxic response of a test compound, to monitor the progression of hepatic disease states, to identify genes that show promise as new drug targets and to screen known and newly designed drugs as discussed above. The databases packaged with the kits are a compilation of expression patterns from human or laboratory animal genes and gene fragments (corresponding to the genes of Tables 1-3). In particular, the database software and packaged information that may contain the databases saved to a computer-readable medium include the expression results of Tables 1-3 that can be used to predict toxicity of a test agent by comparing the expression levels of the genes of Tables 1-3 induced by the test agent to the expression levels presented in Tables 3A-3DD. In another format, database and software information may be provided in a remote electronic format, such as a website, the address of which may be packaged in the kit. The kits may used in the pharmaceutical industry, where the need for early drug testing is strong due to the high costs associated with drug development, but where bioinformatics, in particular gene expression informatics, is still lacking. These kits will reduce the costs, time and risks associated with traditional new drug screening using cell cultures and laboratory animals. The results of large-scale drug screening of pre-grouped patient populations, pharmacogenomics testing, can also be applied to select drugs with greater efficacy and fewer side-effects. The kits may also be used by smaller biotechnology companies and research institutes who do not have the facilities for performing such large-scale testing themselves. Databases and software designed for use with use with microarrays is discussed in Balaban et al., U.S. Pat. No. 6,229,911, a computer-implemented method for managing information, stored as indexed Tables 1-3, collected from small or large numbers of microarrays, and U.S. Pat. No. 6,185,561, a computer-based method with data mining capability for collecting gene expression level data, adding additional attributes and reformatting the data to produce answers to various queries. Chee et al., U.S. Pat. No. 5,974,164, discloses a software-based method for identifying mutations in a nucleic acid sequence based on differences in probe fluorescence intensities between wild type and mutant sequences that hybridize to reference sequences. Without further description, it is believed that one of ordinary skill in the art can, using the preceding description and the following illustrative examples, make and utilize the compounds of the present invention and practice the claimed methods. The following working examples therefore, specifically point out the preferred embodiments of the present invention, and are not to be construed as limiting in any way the remainder of the disclosure. EXAMPLES Example 1 Identification of Toxicity Markers The hepatotoxins acyclovir, amitryptiline, alpha-naphthylisothiocyante (ANIT), acetaminophen, AY-25329, bicalutamide, carbon tetrachloride, clofibrate, cyproterone acetate (CPA), diclofenac, diflunisal, dioxin, 17α-ethinylestradiol, hydrazine, indomethacin, lipopolysaccharide, phenobarbital, tacrine, valproate, WY-14643, zileuton and control compositions were administered to male Sprague-Dawley rats at various time points using administration diluents, protocols and dosing regimes as previously described in the art and previously described in the priority applications discussed above. After adminstration, the dosed animals were observed and tissues were collected as described below: Observation of Animals 1. Clinical Observations—Twice daily: mortality and moribundity check. Cage Side Observations—skin and fur, eyes and mucous membrane, respiratory system, circulatory system, autonomic and central nervous system, somatomotor pattern, and behavior pattern. Potential signs of toxicity, including tremors, convulsions, salivation, diarrhea, lethargy, coma or other atypical behavior or appearance, were recorded as they occurred and included a time of onset, degree, and duration. 2. Physical Examinations—Prior to randomization, prior to initial treatment, and prior to sacrifice. 3. Body Weights—Prior to randomization, prior to initial treatment, and prior to sacrifice. CLINCAL PATHOLOGY1.FrequencyPrior to necropsy.2.Number of animalsAll surviving animals.3.Bleeding ProcedureBlood was obtained by puncture of the orbitalsinus while under 70% CO 2 /30% O 2 anesthesia. 4. Collection of Blood Samples Approximately 0.5 mL of blood was collected into EDTA tubes for evaluation of hematology parameters. Approximately 1 mL of blood was collected into serum separator tubes for clinical chemistry analysis. Approximately 200 uL of plasma was obtained and frozen at ˜−80° C. for test compound/metabolite estimation. An additional ˜2 mL of blood was collected into a 15 mL conical polypropylene vial to which ˜3 mL of Trizol was immediately added. The contents were immediately mixed with a vortex and by repeated inversion. The tubes were frozen in liquid nitrogen and stored at 80° C. Termination Procedures Terminal Sacrifice Approximately 1 and 3 and 6 and 24 and 48 hours and 5-7 days after the initial dose, rats were weighed, physically examined, sacrificed by decapitation, and exsanguinated. The animals were necropsied within approximately five minutes of sacrifice. Separate sterile, disposable instruments were used for each animal, with the exception of bone cutters, which were used to open the skull cap. The bone cutters were dipped in disinfectant solution between animals. Necropsies were conducted on each animal following procedures approved by board-certified pathologists. Animals not surviving until terminal sacrifice were discarded without necropsy (following euthanasia by carbon dioxide asphyxiation, if moribund). The approximate time of death for moribund or found dead animals was recorded. Postmortem Procedures Fresh and sterile disposable instruments were used to collect tissues. Gloves were worn at all times when handling tissues or vials. All tissues were collected and frozen within approximately 5 minutes of the animal's death. The liver sections and kidneys were frozen within approximately 3-5 minutes of the animal's death. The time of euthanasia, an interim time point at freezing of liver sections and kidneys, and time at completion of necropsy were recorded. Tissues were stored at approximately −80° C. or preserved in 10% neutral buffered formalin. Tissue Collection and Processing Liver 1. Right medial lobe—snap frozen in liquid nitrogen and stored at ˜−80° C.2. Left medial lobe—Preserved in 10% neutral-buffered formalin (NBF) and evaluated for gross and microscopic pathology.3. Left lateral lobe—snap frozen in liquid nitrogen and stored at ˜−80° C. Heart A sagittal cross-section containing portions of the two atria and of the two ventricles was preserved in 10% NBF. The remaining heart was frozen in liquid nitrogen and stored at ˜−80° C. Kidneys (Both) 1. Left—Hiemi-dissected; half was preserved in 10% NBF and the remaining half was frozen in liquid nitrogen and stored at ˜−80° C. 2. Right—Hemi-dissected; half was preserved in 10% NBF and the remaining half was frozen in liquid nitrogen and stored at ˜−80° C. Testes (Both) A sagittal cross-section of each testis was preserved in 10% NBF. The remaining testes were frozen together in liquid nitrogen and stored at ˜−80° C. Brain (Whole) A cross-section of the cerebral hemispheres and of the diencephalon was preserved in 10% NBF, and the rest of the brain was frozen in liquid nitrogen and stored at ˜−80° C. Microarray sample preparation was conducted with minor modifications, following the protocols set forth in the Affymetrix GeneChip Expression Analysis Manual. Frozen tissue was ground to a powder using a Spex Certiprep 6800 Freezer Mill. Total RNA was extracted with Trizol (GibcoBRL) utilizing the manufacturer's protocol. The total RNA yield for each sample was 200-500 μg per 300 mg tissue weight. mRNA was isolated using the Oligotex mRNA Midi kit (Qiagen) followed by ethanol precipitation. Double stranded cDNA was generated from mRNA using the SuperScript Choice system (GibcoBRL). First strand cDNA synthesis was primed with a T7-(dT24) oligonucleotide. The cDNA was phenol-chloroform extracted and ethanol precipitated to a final concentration of 1 μg/ml. From 2 μg of cDNA, cRNA was synthesized using Ambion's T7 MegaScript in vitro Transcription Kit. To biotin label the cRNA, nucleotides Bio-11-CTP and Bio-16-UTP (Enzo Diagnostics) were added to the reaction. Following a 37° C. incubation for six hours, impurities were removed from the labeled cRNA following the RNeasy Mini kit protocol (Qiagen). cRNA was fragmented (fragmentation buffer consisting of 200 mM Tris-acetate, pH 8.1, 500 mM KOAc, 150 mM MgOAc) for thirty-five minutes at 94° C. Following the Affymetrix protocol, 55 μg of fragmented cRNA was hybridized on the Affymetrix rat array set for twenty-four hours at 60 rpm in a 45° C. hybridization oven. The chips were washed and stained with Streptavidin Phycoerythrin (SAPE) (Molecular Probes) in Affymetrix fluidics stations. To amplify staining, SAPE solution was added twice with an anti-streptavidin biotinylated antibody (Vector Laboratories) staining step in between. Hybridization to the probe arrays was detected by fluorometric scanning (Hewlett Packard Gene Array Scanner). Data was analyzed using Affymetrix GeneChip® version 2.0 and Expression Data Mining (EDMT) software (version 1.0), GeneExpress2000, and S-Plus. Table 1 discloses those genes that are differentially expressed in liver upon exposure to the named toxins and their corresponding GenBank Accession and Sequence Identification numbers, the identities of the metabolic pathways in which the genes function, the gene names if known, and the unigene cluster titles. The comparison code represents the various toxicity or liver pathology state that each gene is able to discriminate as well as the individual toxin type associated with each gene. The codes are defined in Table 2. The GLGC ID is the internal Gene Logic identification number. Table 2 defines the comparison codes used in Table 1. Tables 3A-3DD disclose the summary statistics for each of the comparisons performed. Each of these tables contains a set of predictive genes and creates a model for predicting the hepatoxicity of an unknown, i.e., untested compound. Each gene is identified by its Gene Logic identification number and can be cross-referenced to a gene name and representative SEQ ID NO. in Table 1. For each comparison of gene expression levels between samples in the toxicity group (samples affected by exposure to a specific toxin) and samples in the non-toxicity group (samples not affected by exposure to that same specific toxin), the group mean (for toxicity group samples) is the mean signal intensity, as normalized for the various chip parameters that are being assayed. The non-group mean represents the mean signal intensity, as normalized for the various chip parameters that are being assayed, in samples from animals other than those treated with the high dose of the specific toxin. These animals were treated with a low dose of the specific toxin, or with vehicle alone, or with a different toxin. Samples in the toxicity groups were obtained from animals sacrificed at the timepoint(s) indicated in the tables, while samples in the non-toxicity groups were obtained from animals sacrificed at all time points in the experiments. For individual genes, an increase in the group mean compared to the non-group mean indicates up-regulation upon exposure to a toxin. Conversely, a decrease in the group mean compared to the non-group mean indicates down-regulation. The mean values are derived from Average Difference (AveDiff) values for a particular gene, averaged across the corresponding samples. Each individual Average Difference value is calculated by integrating the intensity information from multiple probe pairs that are tiled for a particular fragment. The normalization algorithm used to calculate the AveDiff is based on the observation that the expression intensity values from a single chip experiment have different distributions, depending on whether small or large expression values are considered. Small values, which are assumed to be mostly noise, are approximately normally distributed with mean zero, while larger values roughly obey a log-normal distribution; that is, their logarithms are normally distributed with some nonzero mean. The normalization process computes separate scale factors for “non-expressors” (small values) and “expressors” (large ones). The inputs to the algorithm are pre-normalized Average Difference values, which are already scaled to set the trimmed mean equal to 100. The algorithm computes the standard deviation SD noise of the negative values, which are assumed to come from non-expressors. It then multiplies all negative values, as well as all positive values less than 2.0* SD noise, by a scale factor proportional to 1/SD noise. Values greater than 2.0* SD noise are assumed to come from expressors. For these values, the standard deviation SD log (signal) of the logarithms is calculated. The logarithms are then multiplied by a scale factor proportional to 1/SD log (signal) and exponentiated. The resulting values are then multiplied by another scale factor, chosen so there will be no discontinuity in the normalized values from unscaled values on either side of 2.0* SD noise. Some AveDiff values may be negative due to the general noise involved in nucleic acid hybridization experiments. Although many conclusions can be made corresponding to a negative value on the GeneChip platform, it is difficult to assess the meaning behind the negative value for individual fragments. Our observations show that, although negative values are observed at times within the predictive gene set, these values reflect a real biological phenomenon that is highly reproducible across all the samples from which the measurement was taken. For this reason, those genes that exhibit a negative value are included in the predictive set. It should be noted that other platforms of gene expression measurement may be able to resolve the negative numbers for the corresponding genes. The predictive ability of each of those genes should extend across platforms, however. Each mean value is accompanied by the standard deviation for the mean. The linear discriminant analysis score (discriminant score), as disclosed in the tables, measures the ability of each gene to predict whether or not a sample is toxic. The discriminant score is calculated by the following steps: Calculation of a Discriminant Score Let X i represent the AveDiff values for a given gene across the Group 1 samples, i=1 . . . n. Let Y i represent the AveDiff values for a given gene across the Group 2 samples, i=1 . . . t. The calculations proceed as follows: Calculate mean and standard deviation for X i 's and Y i 's, and denote these by m X , m Y , s X , s Y . For all X i 's and Y i 's, evaluate the function f(z)=((1/s Y )*exp(−0.5*((z−m Y )/s Y ) 2 ))/(((1/s Y )*exp(−0.5*((z−m Y )/s Y ) 2 ))+((1/s X )*exp(−0.5*((z−m X )/s X ) 2 ))). The number of correct predictions, say P, is then the number of Y i 's such that f(Y i )>0.5 plus the number of X i 's such that f(X i )<0.5. The discriminant score is then P/(n+t). Linear discriminant analysis uses both the individual measurements of each gene and the calculated measurements of all combinations of genes to classify samples. For each gene a weight is derived from the mean and standard deviation of the tox and nontox groups. Every gene is multiplied by a weight and the sum of these values results in a collective discriminate score. This discriminant score is then compared against collective centroids of the tox and nontox groups. These centroids are the average of all tox and nontox samples respectively. Therefore, each gene contributes to the overall prediction. This contribution is dependent on weights that are large positive or negative numbers if the relative distances between the tox and nontox samples for that gene are large and small numbers if the relative distances are small. The discriminant score for each unknown sample and centroid values can be used to calculate a probability between zero and one as to the group in which the unknown sample belongs. Example 2 General Toxicity Modeling Samples were selected for grouping into tox-responding and non-tox-responding groups by examining each study individually with Principal Components Analysis (PCA) to determine which treatments had an observable response. Only groups where confidence of their tox-responding and non-tox-responding status was established were included in building a general tox model. Linear discriminant models were generated to describe toxic and non-toxic samples. The top discriminant genes and/or EST's were used to determine toxicity by calculating each gene's contribution with homo and heteroscedastic treatment of variance and inclusion or exclusion of mutual information between genes. Prediction of samples within the database exceeded 80% true positives with a false positive rate of less than 5%. It was determined that combinations of genes and/or EST's generally provided a better predictive ability than individual genes and that the more genes and/or EST used the better predictive ability. Although the preferred embodiment includes fifty or more genes, many pairings or greater combinations of genes and/or EST can work better than individual genes. All combinations of two or more genes from the selected list could be used to predict toxicity. These combinations could be selected by pairing in an agglomerate, divisive, or random approach. Further, as yet undetermined genes and/or EST's could be combined with individual or combination of genes and/or EST's described here to increase predictive ability. However, the genes and/or EST's described here would contribute most of the predictive ability of any such undetermined combinations. Other variations on the above method can provide adequate predictive ability. These include selective inclusion of components via agglomerate, divisive, or random approaches or extraction of loading and combining them in agglomerate, divisive, or random approaches. Also the use of composite variables in logistic regression to determine classification of samples can also be accomplished with linear discriminate analysis, neural or Bayesian networks, or other forms of regression and classification based on categorical or continual dependent and independent variables. Example 3 Modeling Methods The above modeling methods provide broad approaches of combining the expression of genes to predict sample toxicity. One could also provide no weight in a simple voting method or determine weights in a supervised or unsupervised method using agglomerate, divisive, or random approaches. All or selected combinations of genes may be combined in ordered, agglomerate, or divisive, supervised or unsupervised clustering algorithms with unknown samples for classification. Any form of correlation matrix may also be used to classify unknown samples. The spread of the group distribution and discriminate score alone provide enough information to enable a skilled person to generate all of the above types of models with accuracy that can exceed discriminate ability of individual genes. Some examples of methods that could be used individually or in combination after transformation of data types include but are not limited to: Discriminant Analysis, Multiple Discriminant Analysis, logistic regression, multiple regression analysis, linear regression analysis, conjoint analysis, canonical correlation, hierarchical cluster analysis, k-means cluster analysis, self-organizing maps, multidimensional scaling, structural equation modeling, support vector machine determined boundaries, factor analysis, neural networks, bayesian classifications, and resampling methods. Example 4 Grouping of Individual compound and Pathology Classes Samples were grouped into individual pathology classes based on known toxicological responses and observed clinical chemical and pathology measurements or into early and late phases of observable toxicity within a compound (Tables 3A-3DD). The top 10, 25, 50, 100 genes based on individual discriminate scores were used in a model to ensure that combination of genes provided a better prediction than individual genes. As described above, all combinations of two or more genes from this list could potentially provide better prediction than individual genes when selected in any order or by ordered, agglomerate, divisive, or random approaches. In addition, combining these genes with other genes could provide better predictive ability, but most of this predictive ability would come from the genes listed herein. Samples may be considered toxic if they score positive in any pathological or individual compound class represented here or in any modeling method mentioned under general toxicology models based on combination of individual time and dose grouping of individual toxic compounds obtainable from the data. The pathological groupings and early and late phase models are preferred examples of all obtainable combinations of sample time and dose points. Most logical groupings with one or more genes and one or more sample dose and time points should produce better predictions of general toxicity, pathological specific toxicity, or similarity to known toxicant than individual genes. Although the present invention has been described in detail with reference to examples above, it is understood that various modifications can be made without departing from the spirit of the invention. Accordingly, the invention is limited only by the following claims. All cited patents, patent applications and publications referred to in this application are herein incorporated by reference in their entirety. TABLE 1Document Number 1740956GenBankModelKnownUnigeneGLGC IDSeqIDAccCodePathway NameGene NameCluster Title16419274AA875102GeneralESTs, Highly similar to RUXE_HUMAN SMALL NUCLEAR RIBONUCLEO-PROTEIN E [ M.musculus ]225142418X13983yAlpha-2-macroglobulinAlpha-2-macroglobulin23360605AA955104GeneralESTs22705588AA946032eESTs22979199AA851372xESTs, Highly similar to R26445 1 [ H.sapiens ]24458761AB003515dganglioside expressionganglioside expression factor 2 factor 254921969D38061f,qAndrogen and estrogenUDP-glucuronosyltransferaseESTs, UDP-glucuronosyltransferase 1 family, member 1metabolism, Pentose and1 family, member 1glucuronate interconversions,Porphyrin and chlorophyllmetabolism, Starch andsucrose metabolism22641333AI144741qESTs5026459AA924783GeneralEST24665874AI009098oESTs74141323AI137586iESTs, Highly similar to IMB3_HUMAN IMPORTIN BETA-3 SUBUNIT [ H.sapiens ]67351464AI172497fRattus norvegicus mRNA for peptide histidine transporter 1 homolog rPHT2, completecds177092319U24489nTenascin XTenascin X22490394AA899289g,qESTs, Moderately similar to KIAA1049 protein [ H.sapiens ]23417784AB022209General,ddribonucleoprotein Fribonucleoprotein F208992478X65948aageneral transcriptiongeneral transcription factor IIB factor IIB10692423X15096a,wacidic ribosomal proteinacidic ribosomal protein P0 P019772072J05470k,o,bbFatty acid metabolism,Camitine palmitoyltrans-Camitine palmitoyltransferase 2 ferase 2Glycerolipid metabolism155431729AI231800d,GeneralRattus norvegicus brain Na++/Ca++ exchanger-associated protein mRNA, complete cds78641931D10874tOxidative phosphorylation,HMm:ATPase, H+ transporting,Rattus norvegicus mRNA for K(+)− transporting ATPase, complete cds pump) 16kDType III proteinlysosomal (vacuolar protonsecretion system1645921139AI070315j,GeneralESTs, Weakly similar to NFAT1-A [ M.musculus ]44343AA685221hESTs622692AA818521vESTs4271488AA925603k,o,zESTs, Moderately similar to AF153605 1 androgen induced protein [ H.sapiens ]234351664AI229502jESTs, Highly similar to KIAA0601 protein [ H.sapiens ]154651860AI236280d,Generalprotein Sprotein S18692061J03959p,tPurine metabolismHMm:urate oxidaseRat urate oxidase 2 mRNA, complete cds9254333AA892470d,GeneralESTs, Highly similar to HISTONE H2A.Z [ R.norvegicus ]15089899AI009752GeneralESTs111522234M91652General,x,ccGlutamate metabolism,Glutamine synthetaseGlutamine synthetase (glutamate-ammonia ligase) ligase)Nitrogen metabolism(glutamate-ammonia22713582AA945904pESTs19438127AA819450General,u,wEST24366627AA956246m,n,GeneralESTs, Moderately similar to T46373 hypothetical protein DKFZp434B2119.1[ H.sapiens ]3665881AI009376c,General,bbESTs, Moderately similar to A34168 nucleolar phosphoprotein B23.2 - rat [ R.norvegicus ]19269202AA851785GeneralESTs, Highly similar to NIPI-like protein [ M.musculus ]6824133AA819709dRattus norvegicus mRNA for beta-carotene 15,15′-dioxygenase, complete cds1603911AA799452etransaldolase 1transaldolase 1242842236M94287ynucleolar phosphoproteinnucleolar phosphoprotein p130 p130174481666AI229637GeneralMYB binding proteinMYB binding protein (P160) 1a (P160) 1a56222403X05834b,xFibronectin 1Fibronectin 1211641319AI137488GeneralESTs14495377AA893658p,wESTs17963775AB012231Generalnuclear factor I/Bnuclear factor I/B6613150AA848758kButanoate metabolism,HMm:hydroxylacyl-CoenzymeRattus norvegicus L-3-hydroxyacyl-CoA dehydrogenase precursor (HAD) mRNA,Fatty acid biosynthesisA dehydrogenasecomplete cds;(path 2), Fatty acidnuclear gene for mitochondrial productmetabolism, Lysinedegradation, Tryptophanmetabolism, Valine, leucineand isoleucine degradation14962350U56839Generalpurinergic receptor P2Y,purinergic receptor P2Y, G-protein coupled 2G-protein coupled 221957831AF087437fESTs24161211AA858588eESTs161642280S83025ccY box protein 1Y box protein 1209842002D90109g,hFatty acid metabolismAcyl CoA synthetase,Acyl CoA synthetase, long chain long chain247982406X06357o,tAlanine and aspartateAlanine-glyoxylateAlanine-glyoxylate aminotransferase (Serine-pyruvate aminotransferase)metabolism, Glycine,aminotransferaseserine and threonine(Serine-pyruvatemetabolismaminotransferase)89832095L10652ainitiation factor 2initiation factor 2 associated 67 kDa protein proteinassociated 67 kDa2106547AA800179ddESTs, Highly similar to hypotheticalprotein COX4AL [ M.musculus ]14272122L38644vImportin betaImportin beta153012207M60921cB-cell translocationB-cell translocation gene 2, anti-proliferativegene 2, anti-proliferative22993846AI007872gESTs, Moderately similar to S12207 hypothetical protein [ M.musculus ]169068AA81729mESTs150021365AI169327u,wRattus norvegicus tissue inhibitor of metalloproteinase-1 (TIMP1), mRNA, complete cds3393740AA998209aESTs32661440AI171948GeneralESTs, Highly similar to T08675 hypothetical protein DKFZp564F0522.1 [ H.sapiens ]23440462AA924881GeneralESTs, Weakly similar to KIAA0365 [ H.sapiens ]255672282S85184t,y180292191M38759kHistidine metabolismHistidine decarboxylaseHistidine decarboxylase231571463AI172489jESTs, Moderately similar to STRI RAT STRIATIN [ R.norvegicus ]44791285AI111599GeneralESTs151881947D16302p,GeneralGlycoprotein biosynthesisN-acetylglucos-N-acetylglucosaminyltransferase Iaminyltransferase I218391165AI071644GeneralESTs, Moderately similar to LMG1 MOUSE LAMININ GAMMA-1 CHAIN PRECURSOR[ M.musculus ]19732205M60103e,Generalprotein tyrosineprotein tyrosine phosphatase, receptor-type, Fphosphatase, receptor-type, F14324176AA850402bESTs, Moderately similar to S21348 probable pol polyprotein-related protein 4 - rat[ R.norvegicus ]23347257AA860015aaESTs, Weakly similar to T50607 hypothetical protein DKFZp434I1016.1 [ H.sapiens ]114041881AI237002d,rspermidine synthasespermidine synthase216431271AI104544wribosomal protein S17ribosomal protein S17172112185M34331tESTs, Weakly similar to KRAB-zinc finger protein KZF-1 [ R.norvegicus ]263351864AI236460nRattus norvegicus retinol dehydrogenase type II mRNA, complete cds722193M57263utransglutaminase 1,transglutaminase 1, K polypeptideK polypeptide16043266AA874830rESTs, Weakly similar to PRTS RAT VITAMIN K-DEPENDENT PROTEIN SPRECURSOR [ R.norvegicus ]114651851AI236084uESTs, Moderately similar to 41BB MOUSE 4-1BB LIGAND RECEPTOR PRECURSOR[ M.musculus ]91921316AI137345q,zESTs15987262AA866435l,ccEST108291057AI044467vEST21382575AA945708i,GeneralESTs218642018H31144GeneralESTs, Moderately similar to 1914275A non-receptor Tyr kinase [ H.sapiens ]21173155AA848990GeneralESTs27891824AI234949t,aaRattus norvegicus mRNA for protein protein19412158AA849222General,yESTs, Moderately similar to AC006978 1 supported by human and rodent ESTs[ H.sapiens ]16842452X56325nHemoglobin, alpha 1Hemoglobin, alpha 188991259AI03957d,eCD81 antigen (target ofCD81 antigen (target of antiproliferative antibody 1)antiproliferativeantibody 1)11827240AA859468vESTs94232255S61868a,gRyudocan/syndecan 4Ryudocan/syndecan 43310732AA997945nESTs23272617AA955819lESTs9112344U49729aaBcI2-associated XBcI2-associated X proteinprotein126132021H31620GeneralESTs, Highly similar to hypothetical protein [ H.sapiens ]12093148AA848628oESTs, Highly similar to N-acetylglucosamine-phosphate mutase [ H.sapiens ]5882480X69834d,pR.norvegicus mRNA for serine protease inhibitor 2.4255632277S81497hESTs, Weakly similar to mitochondrial56021760AI232611oESTs, Weakly similar to mitochondrial very-long-chain acyl-CoA thioesterase[ R.norvegicus ]57111074AI045151r,GeneralESTs, Moderately similar to AF118838 1 citrin [ H.sapiens ]19252316AA892041dMethane metabolism,HMm:peroxiredoxinRattus norvegicus mRNA for thiol-specific antioxidant protein (1-Cys peroxiredoxin)Phenylalanine5metabolism163211726AI231506GeneralESTs23491538AA944422Generalacidic calponinacidic calponin4954449AA924444jESTs44441199AI100882c,m,GeneralESTs, Moderately similar to homology to a plant EST:RICS2753A [ H.sapiens ]240131659AI229260rESTs289776AA818039jESTs61011401AI170752rESTs2932074J05499p,GeneralRattus norvegicus L-glutamine amidohydrolase mRNA complete cds236992044J02749k,o,p,ccBile acid biosyntheses,Acetyl-CoA acyltransferase,Acetyl-CoA acyltransferase, 3-oxo acyl-CoA thiolase A, peroxisomalFatty acid biosynthesis3-oxo acyl-CoA thiolase(path 2), Fatty acidA, peroxisomalmetabolism, Phenylalaninemetabolism, Valine, leucineand isoleucine degradation117621583AI178631mESTs256932444X53949bb203082453X56327hR.norvegicus beta-hO-r gene for beta-globin chain105731200AI101003yESTs, Weakly similar to S70642 ubiquitin ligase Nedd4 - rat [ R.norvegicus ]16521918AI010470oPorphyrin andCeruloplasmin (ferroxidase)Ceruloplasmin (ferroxidase)chlorophyll metabolism4751415AA900481xESTs12361693AA965031GeneralESTs113261010AI029015GeneralESTs23578603AA955042aESTs, Weakly similar to folate binding protein [ R.norvegicus ]21696533AA944324iADP-ribosylation factor 6ADP-ribosylation factor 6187052173M30691aLy6-C antigen geneLy6-C antigen gene250782333U33540a,GeneralESTs263301844AI235911a226861791AI233753aaESTs702198M58308p,GeneralHistidine metabolism,histidine ammonia lyasehistidine ammonia lyaseNitrogen metabolism6554840AF097723c,dplasma glutamateplasma glutamate carboxypeptidasecarboxypeptidase15148237AA859325zESTs, Weakly similar to T26289 hypothetical protein W08E3.1 - Caenorhabditis elegans[ C.elegans ]24012649AA957335bESTs21952295AA891537rESTs, Weakly similar to unknown [ H.sapiens ]5215495AA925774bbESTs4245100AA818692pESTs, Moderately similar to ribosomal protein L33-like protein [ H.sapiens ]8192392X02284k,m,nCarbon fixation,Aldolase B, fructose-Aldolase B, fructose-biphosphateFructose and mannosebiphosphatemetabolism, Glycolysis/Gluconeogenesis, Inositolmetabolism, Pentosephosphate cycle1142236AA799812c,uESTs, Moderately similar to PTN3_HUMAN PROTEIN TYROSINE PHOSPHATASE,NON-RECEPTOR TYPE 3 [ H.sapiens ]582301U09870imajor vault proteinmajor vault protein17817349AA892777qESTs, Moderately similar to ribonuclease HI large subunit [ H.sapiens ]206502131M12335n,xArginine and prolineCarboamyl-phosphateCarboamyl-phosphate synthetase 1metabolism, Glutamatesynthetase 1metabolism, Nitrogenmetabolism, Urea cycleand metabolism of aminogroups14737861AI008416g,rESTs250552127M11251l,x,ddESTs, Highly similar to DDRT helix-1501140AA799893GeneralESTs, Highly similar to DDR helix-destabilizing protein - rat [ R.norvegicus ]4174943AI011613bbESTs208021114AI059508oCarbon fixation, Pentosetransketolasetransketolasephosphate cycle402555AA945143bTryptophan metabolismtryptophan-2,3-tryptophan-2,3-dioxygenasedioxygenase156102114L27075kCitrate cycle (TCA cycle)ATP citrate lyaseATP citrate lyase61431279AI105167f,p,q,uESTs, Moderately similar to selenium-binding protein [ H.sapiens ]21856210AA858550pESTs7252356U62316zsolute carrier familysolute carrier family 16 (monocarboxylic acid transporters), member 716 (monocarboxylic acidtransporters), mem24112864AI008773xESTs18908161AA849426vESTs, Weakly similar to YLC4_CAEELHYPOTHETICAL 81.0 KD PROTEIN C35D10.4 IN CHROMOSOME III [ C.elegans ]142311174AI072358p,qESTs105452316U21871r,yRattus norvegicus outer mitochondrial membrane receptor rTOM20 mRNA, completecds6783701AA996463GeneralESTs19370669AA963797General,yESTs11998352AA892828zButanoate metabolism,HHs:pyruvate dehydrogenaseESTs, Highly similar to ODPB RAT PYRUVATE DEHYDROGENASE E1Glycolysis/Gluconegenesis,(lipomide) betaCOMPONENT BETA SUBUNIT, MITOCHONDRIAL PRECURSOR [ R.norvegicus ]Pyruvate metabolism, Valine,leucine and isoleucinebiosynthesis203542137M14369m,uK-kininogen, differentialK-kininogen, differential splicing leads to HMW Kngksplicing leads to HMW Kngk16984984AI013161cESTs, Highly similar to EF1G_HUMAN ELONGATION FACTOR 1-GAMMA[ H.sapiens ]60471195AI073230GeneralESTs16312268AA875032nESTs2888463AA924902k,GeneralESTs22870508AA926360j,GeneralESTs15615532AA944316ccRattus norvegicus thioredoxin mRNA, complete cds15372277AA875205GeneralESTs, Highly similar to IF39_HUMAN EUKARYOTIC TRANSLATIONINITIATION FACTOR 3 SUBUNIT 92424684AA964617f,gESTs1450435AA799804zESTs143841543AI77096General,wPurine metabolismHMm:adenine phosphoribosylRat adenine phosphoribosyltransferas (APRT) gene, complete cdstransferase238601888AI237684dESTs1840043AA799991vESTs175311662AI229440ccAminosugars metabolismHHs:diaphorase (NADH)Rat NADH-cytochrome b-5 reductase mRNA, complete cds(cytochrome b-5 reductase)152811937D13623GeneralESTs1127760AB003400pArginine and prolineHMm:D-amino acidRattus norvegicus mRNA for D-amino-acid oxidase, complete cdsmetabolism, D-Arginineand D-ornithine metabolism,Glycine, serine andthreonine metabolism3924186AA851017ccESTs, Highly similar to molybdopterin-synthase large subunit [ M.musculus ]187281406AI170776hgrowth factor receptorgrowth factor receptor bound protein 2bound protein 2134461696AI230625GeneralESTs25391289AI111960GeneralESTs, Weakly similar to FKB5 MOUSE 51 KDA FK506-BINDING PROTEIN[ M.musculus ]22250522AA943541g,qESTs, Weakly similar to T19468 hypothetical protein C25G4.2 - Caenorhabditis elegans[ C.elegans ]161901269AI04482kESTs, Weakly similar to ECHM RAT ENOYL-COA HYDRATASE, MITO-CHONDRIAL PRECURSOR [ R.norvegicus ]1112286U02506nRattus norvegicus clone 15 polymeric immunoglobulin receptor mRNA, 3′UTRmicrosatellite repeats9215467AA925116winterferon gamma inducinginterferon gamma inducing factor binding proteinfactor binding protein94321190AI072914General,yEST39171768AI232970GeneralESTs17837376AA893641cESTs, Weakly similar to 1901177A wnt-2 gene [ R.norvegicus ]55731101AI059063aESTs, Weakly similar to gamma-fibrinogen [ R.norvegicus ]15638287AA875633zESTs247122012E01884m,uinteract6-1Interleukin 1 betaInterleukin 1 beta40261802AI233835m,uESTs137961656AI229056j,mESTs12312373AA893453d,ccESTs15401282AA875257GeneralESTs6188106AA818774GeneralESTs254702242M95791m1657622AA799570jESTs180362341U40004d,GeneralRattus norvegicus cytochrome P450 pseudogene (CYP2J3P1) mRNA121582091L00320k,l,x,cc,dd170912368U73174f,g,l,GeneralRattus norvegicus glutathione reductase mRNA, complete cds159201594AI78938iESTs12211933D11445m,n,ugrogro43651137AI070200wESTs, Weakly similar to T24938hypothetical protein T15H9.1 - Caenorhabditis elegans [ C.elegans ]175022130M12156i,rheterogeneous nuclearheterogeneous nuclear ribonucleoprotein A1ribonucleoprotein A114621841AI235585fRat mRNA for preprocathepsin D (EC 3.4.23.5)210782046J02791d,k,l,GeneralFatty acid metabolism,Acyl-Coenzyme AAcyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chainPropanoate metabolism,dehydrogenase, C-4Valine, leucine andto C-12 straight-chainisoleucine degradation,beta-Alanine metabolism22266569AA945601j,GeneralESTs3131364AA893032d,eESTs17340843AI007803b,mERM-binding phosphoproteinERM-binding phosphoprotein22655531AA944308GeneralESTs, Highly similar to N214_HUMAN NUCLEAR PORE COMPLEXPROTEIN NUP214 [ H.sapiens ]54932251S56936f,qAndrogen and estrogenUDP-glucuronosyltrans-ESTs,UDP-glucuronosyltransferase 1 family, member 1metabolism, Pentose andferase 1 family, member 1glucuronate interconversions,Porphyrin and chlorophyllmetabolism, Starch andsucrose metabolism180281970D38062p,qRattus norvegicus UDP-glucuronosyltransferase UGT1A7 mRNA, complete cds183542462X59859m,udecorindecorin50341393AI170613tHeat shock 10 kD proteinHeat shock 10 kD protein 1 (chaperonin 10)1 (chaperonin 10)161631936D13309tY box protein 1Y box protein 147811806AI233925General5-aminoimidazole-4-5-aminoimidazole-4-carboxamidecarboxamide ribonucleotideribonucleotide formyltransferase/IMP cyclohydrolaseformyltransferase/207751477AI75494GeneralESTs, Moderately similar to PTD004 [ H.sapiens ]50591879AI236947GeneralESTs218822223M83740hdimerization cofactor ofRattus norvegicus DCoH genehepatocyte nuclearfactor-1-alpha56672456X58200h,wribosomal protein L231653810AA799449a,ddESTs, Weakly similar to nucleosome assembly protein [ R.norvegicus ]2013332AA892390cSolute carrier family 11Solute carrier family 11 member 2 (natural resistance-associated macrophagemember 2 (naturalprotein 2)resistance-associatedmacrophage protein 2)7642501X84210rNuclear Factor IANuclear Factor IA18717551AA945050hAndrogen and estrogenRat senescence markerRat senescence marker protein 2A gene, exons 1 and 2 1 and 2metabolismprotein 2A gene, exons4007501AA926066pESTs6409228AA858910oESTs11966304AA891800dESTs, Highly similar to KIAA0694 protein [ H.sapiens ], ESTs, Moderately similar topyrophosphatase [ H.sapiens ]204432309U14192ddtranscytosis associatedtranscytosis associated protein, vesicle docking protein, 115 kDaprotein, vesicle dockingprotein, 115 kDa4892006E00778g,p,q,ddFatty acid metabolism,Cytochrome P450, subfamilyCytochrome P450, subfamily I (aromatic compound-inducible), member Al (C6, form c)Tryptophan metabolismI (aromatic compound-inducible), member A1(C6, form c)194082395X02610eGluconeogenesis,Enolase 1, alphaEnolase 1, alphaPhenylalanine,tyrosine and tryptophanbiosynthesis85491785AI233639nESTs101092458X58465h,w,ccRibosomal protein S5Ribosomal protein S520795536AA944397z,ddESTs, Moderately similar to HS9B RAT HEAT SHOCK PROTEIN HSP 90-BETA[ R.norvegicus ]65021578AI78283GeneralESTs, Highly similar to AF123263 1 phenylalanyl tRNA synthetase beta subunit[ M.musculus ]9514184AA850978gESTs256082348U53927h18761024AI030175f,n,ccFructose and mannoseSorbitol dehydrogenaseSorbitol dehydrogenasemetabolism13912479X66366zgephyringephyrin16649814AF051895rAnnexin VAnnexin V186112456X58200wribosomal protein L23ESTs, Highly similar to RL23_HUMAN 60S RIBOSOMAL PROTEIN L23[ R.norvegicus ]18713972AI012604teukaryotic initiationeukaryotic initiation factor 5 (eIF-5)factor 5 (eIF-5)74971364AI169302GeneralSphingophospholipidHHs:sphingomyelinESTs, Moderately similar to sphingomyelin phosphodiesterase 1, acid lysosomalbiosynthesisphosphodiesterase[ H.sapiens ]1, acid lysosomal(acid sphingom146971821AI234834aaRattus norvegicus protein associating with small stress protein PASS1 (Pass1) mRNA,complete cds6842900AI009764lESTs38161788AI233729fESTs, Highly similar to PSD5_HUMAN 26S PROTEASOME SUBUNIT S5B[ H.sapiens ]217121361AI169249GeneralESTs96211476AI175486Generalribosomal protein S7ribosomal protein S7147661842AI235886aaESTs250842408X06769w160531646AI228596GeneralESTs, Weakly similar to T16757 hypothetical protein R144.3 - Caenorhabditis elegans[ C.elegans ]3381363AA892993lESTs58841914AJ223184iRattus norvegicus mRNA for DORA protein12447638AA956769f,ccESTs252811967D30804f,l,General17742057J03754zATPase isoform 2, Na+K+ATPase isoform 2, Na+K+ transporting, beta polypeptide 2transporting, betapolypeptide 21691076AI045171bcalsequestrin 2calsequestrin 2188241741AI232255mESTs, Moderately similar to S12207 hypothetical protein [ M.musculus ]114552165M24604GeneralProliferating cellProliferating cell nuclear antigennuclear antigen21993519AA943149GeneralESTs, Weakly similar to T00084 hypothetical protein KIAA0512 [ H.sapiens ]203862364U68562Generalheat shock proteinheat shock protein 60 (liver)60 (liver)167262228M86235hFructose and mannoseKetohexokinaseKetohexokinasemetabolism6408226AA858902t,aaESTs, Weakly similar to S24169 mucin - rat [ R.norvegicus ]15292793AF012714General,tmultiple inositolmultiple inositol polyphosphate histidine phosphatase 1polyphosphate histidinephosphatase 189891147AI070792nESTs110391840AI235465i,Generalsteroid sensitivesteroid sensitive gene-1 proteingene-1 protein6263893AI009666l,General,yaminopeptidase ARattus norvegicus aminopeptidase A short variant mRNA, partial cds39091377AI169903iESTs158752465X62145hribosomal protein L8ESTs, Highly similar to RL8_HUMAN 60S RIBOSOMAL PROTEIN L [ R.norvegicus ]179211506AI176422hESTs, Highly similar to ETFD_HUMAN ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE PRECURSOR [ H.sapiens ]16619717AA997544x,ddEST209442497X82396wcathepsin Bcathepsin B57801571AI177869i,jESTs, Weakly similar to DRAL [ R.norvegicus ]2681429AA901043xESTs14987216AA858640k,Generalheat shock proteinRattus norvegicus CDK110 mRNA, heat shock protein 60 (liver)60 (liver)59981907AI639501GeneralESTs23868798AF023087GeneralEarly growth response 1Early growth response 19952294AA891422GeneralESTs, Moderately similar to AF077034 1 HSPC010 [ H.sapiens ]88641140AI070319a,fESTs262581559AI177501k102451118AI059701v,ddESTs5632532Z50051aComplement component 4Complement component 4 binding protein, alphabinding protein, alpha41551100AI059014tESTs23862310AA891933aaESTs, Moderately similar to A Chain A, Crystal Structure Of SmacDIABLO[ H.sapiens ]53391432AI171727General,tESTs, Weakly similar to phenylethanolamine N-methyltransferase [ R.norvegicus ]135631795AI233773p,q,General,wESTs, Weakly similar to T24413 hypothetical protein T04A11.2 - Caenorhabditis elegans[ C.elegans ]26151660AI229318fESTs151252071J05132f,g,h,xAndrogen and estrogenUDP-glucuronosyltrans-Rattus norvegicus UDP-metabolism, Pentose andferase 1 family,glucuronosyltransferase UGT1A7 mRNA, complete cds, UDP-glucuronosyltransferase 1glucuronate inter-member 1family, member 1conversions, Porphyrinand chlorophyll metabolism,Starch and sucrosemetabolism19129527AA943990pESTs1460061AA801076m,General,uESTs55931698AI230698g,GeneralWolfram syndrome 1Wolfram syndrome 1 (wolframin)(wolframin)9942510AA942697GeneralESTs232601371AI169617a,GeneralESTs, Highly similar to Bop1 [ M.musculus ]193671095AI058745gEST, Weakly similar to HEPC HUMAN ANTIMICROBIAL PEPTIDE HEPCIDINPRECURSOR [ H.sapiens ]210132047J02810a,x,ccGlutathione metabolismGlutathione-S-Glutathione-S-transferase, mu type 2 (Yb2)transferase, mu type 2(Yb2)76501682AI230142eESTs, Weakly similar to KUPFFER CELL RECEPTOR [ R.norvegicus ]11261712AI231007rRattus norvegicus cca1 mRNA, complete cds228491927D10754cESTs, Highly similar to PROTEASOME DELTA CHAIN PRECURSOR[ R.norvegicus ]15283209AA858548GeneralESTs872897AA818615GeneralESTs4050854AI008094gESTs3472284U01914c,ddRattus norvegicus AKAP95 mRNA, partial cds18890408AA899964k,o,GeneralESTs58971086AI045862GeneralESTs, Moderately similar to S64732 scaffold attachment factor B [ H.sapiens ]12933667AA963682cRattus norvegicus 190 kDa ankyrin isoform mRNA, complete cds200561908AI639504GeneralESTs, Weakly similar to T13607 hypothetical protein EG:87B1.3 - fruit fly[ D.melanogaster ]130541609AI79560GeneralESTs20701272AA875097b,wRat alpha-fibrinogen mRNA, 3′ end64782404X05861nFibrinogen, gammaFibrinogen, gamma polypeptidepolypeptide208102419X14181h,w,ccESTs, Highly similar to 60S RIBOSOMAL PROTEIN L18A [ R.norvegicus ]155171976D42145uInwardly rectifyingInwardly rectifying potassium channel gene, subfamily J-8 (ATP sensitive)potassium channel gene,subfamily J-8 (ATPsensitive)20711445AA924267k,o,z,bbFatty acid metabolism,Cytochrome P450,Cytochrome P450, subfamily IVB-polypeptide 1Tryptophan metabolismsubfamily IVB,polypeptide 156162090L00191bFibronectin 1Fibronectin 1209262274S81353ddProsaposin (sulfatedProsaposin (sulfated glycoprotein,glycoprotein, sphingolipidsphingolipid hydrolase activator), enoyl hydratase-like protein, peroxisomalhydrolase activator),enoyl hydratase-likeprotein, peroxisomal34341735AI232014GeneralESTs151381735AI009801lmacrophage migrationmacrophage migration inhibitory factorinhibitory factor245082186M34643vneurotrophin-3 (HDNF/NT-3)neurotrophin-3 (HDNF/NT-3)257022458X58465cc183562246R47042adecorindecorin118502245R46985r,Generalribosomal protein L10aribosomal protein L10a1565417AA799501GeneralOxidative phosphorylation,NADH ubiquinone oxido-NADH ubiquinone oxidoreductase subunit B13Ubiquinone biosynthesisreductase subunit B13247971938D13667tAlanine and aspartateAlanine-glyoxylate amino-Alanine-glyoxylate aminotransferase (Serine-pyruvate aminotransferase)metabolism, Glycine,transferase (Serine-serine and threoninepyruvate aminotransferase)metabolism188371426AI171583GeneralESTs, Moderately similar to PLTP MOUSE PHOSPHOLIPID TRANSFER PROTEINPRECURSOR [ M.musculus ]113311340AI145556aaESTs17693297AA891737GeneralESTs2292314U20194dRattus norvegicus complement C8 beta (C8b) mRNA, partial cds139767AA817787jESTs, Highly similar to hypothetical protein [ H.sapiens ]1634638AA799824iOxidative phosphorylation,HHs:ATPase, H+ESTs, Highly similar to VATC_HUMANType III protein secretiontransporting, lysosomalVACUOLAR ATP SYNTHASE SUBUNIT C [ H.sapiens ]system(vacuolar proton pump)42kD143112305U10699uG-protein coupledG-protein coupled receptor 13receptor 13217032377U82591rRattus norvegicus RCL (Rcl) mRNA, complete cds187551867AI236599GeneralESTs, Highly similar to T50630 hypothetical protein DKFZp762NO610.1 [ H.sapiens ]1995807AF038870t,u,ccGlycine, serine andbetaine-homocysteinebetaine-homocysteine methyltransferasethreonine metabolism,methyltransferaseMethionine metabolism3582346U52948hRattus norvegicus complement component C9 precursor mRNA, partial cds83101593AI178868ddESTs247222172M30282bbPlasma kallikreinPlasma kallikrein2250964AI012354j,yESTs, Highly similar to 0506206A histone H2B [ R.norvegicus ]121841394AI170621GeneralESTs, Weakly similar to YN57_YEAST HYPOTHETICAL 53.1 KD TRP-ASPREPEATS CONTAINING PROTEIN IN HXT14-PHA2 INTERGENIC REGION[ S.cerevisiae ]2138056AA800739GeneralESTs, Weakly similar to KT12_YEAST KTI12 PROTEIN [ S.cerevisiae ]145211749AI232350GeneralESTs, Weakly similar to coding sequence of pol [ R.norvegicus ]15476539AA944426aaRattus norvegicus calmodulin III (Calm3) mRNA, 3′ untranslated region18597778AB013732q,ccNucleotide sugarsUDP-glucoseUDP-glucose dehydrogeansemetabolism, Pentose anddehydrogeanseglucuronate interconver-sions, Starch and sucrosemetabolism4066999AI013782bESTs1116663AA801346yESTs, Weakly similar to JC4975 plexin 2 precursor - mouse [ M.musculus ]19912221M83196yMicrotubule-associatedMicrotubule-associated protein 1aprotein 1a106671862AI236366Generalsiah binding protein 1;siah binding protein 1; FBP interacting repressor; pyrimidine tract bindingFBP interactingsplicing factor; Ro ribonucleoprotein-binding protein 1repressor; pyrimidine tr17560666AA963674geukaryotic translationmitogen activated protein kinase kinase 2elongation factor 2,mitogen activated proteinkinase 213330724AA997716fRattus norvegicus cytosolic inhibitor of Nrf2 (INrf2) mRNA, complete cds114881509AI176477bbESTs, Highly similar to transmembrane protein [ H.sapiens ]23033255AA859938gESTs, Highly similar to NIPL MOUSE BCL2/ADENOVIRUS E1B 19-KDA PROTEIN-INTERACTING PROTEIN 3 LIKE [ M.musculus ]228541292AI112101GeneralESTs, Highly similar to RXRA RAT RETINOIC ACID RECEPTOR RXR-ALPHA[ R.norvegicus ]22603811AF044574k,o,bbputative peroxisomalputative peroxisomal 2,4-dienoyl-CoA reductase2,4-dienoyl-CoAreductase173052460X59051fRibosomal protein S29Ribosomal protein S29245011734AI232006GeneralRattus norvegicus translation elongation factor 1-delta subunit mRNA, partial cds193711197AI100841ddESTs204302069J05035pAndrogen and estrogenSteroid-5-alpha-Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-metabolism, Bilereductase, alpha poly-dehydrogenase alpha 1)acid biosynthesispeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydro-genase alpha 1)241701342AI45601e,GeneralESTs22416535AA944380k,oESTs, Weakly similar to T26648 hypothetical protein Y38A8.1 - Caenorhabditis elegans[ C.elegans ]11752492X79081u,cc,ddFatty acid metabolism,Cytochrome P450, subfamilyCytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase)Tryptophan metabolismIIC (mephenytoin 4-hydroxylase)11691548AI177161q,rNF-E2-related factor 2NF-E2-related factor 2131872318U23056pcarcinoembryonic antigen-carcinoembryonic antigen-related cell adhesion moleculerelated cell adhesionmolecule178471577AI178214oESTs185621479AI175515GeneralESTs, Highly similar to PRTP MOUSE LYSOSOMAL PROTECTIVE PROTEINPRECURSOR [ M.musculus ]20839296AA891729wribosomal protein S27aribosomal protein S27a162052407X06423cribosomal protein S8ribosomal protein S84452933AI011196GeneralValine, leucine andIsovaleryl Coenzyme AIsovaleryl Coenzyme A dehydrogenaseisoleucine degradationdehydrogenase17906402AA899762nRattus norvegicus epidermal growth factor receptor related protein (Errp) mRNA,complete cds762789AF007107x,cccytochrome b5cytochrome b53845941AI011481nESTs3191981AI013075GeneralESTs, Weakly similar to T03454 ALR protein [ H.sapiens ]19009173AA850164qESTs12164187AA851029aaESTs190041489AI175875uESTs21115829AF086624rserine threonine kinaseserine threonine kinase pim3pim3205552322U26033k,ocarnitine octanoyltrans-carnitine octanoyltransferaseferase92232189M36151uRat mRNA for MHC class II antigen RT1.B 1 beta-chain, Rattus norvegicus MHCclass II antigen RT1.B beta chain mRNA, partial cds6781149AA848753qFatty acid metabolismAcyl Coenzyme A dehy-Acyl Coenzyme A dehydrogenase, long chaindrogenase, long chain36641418AI171289pESTs, Highly similar to JC2472 brain and reproductive organ-expressed protein[ H.sapiens ]15075283AA875269istearoyl-CoA desaturase 2stearoyl-CoA desaturase 216345986AI013250f,pRattus norvegicus zinc finger protein Y1 (RLZF-Y) mRNA, complete cds142561529AI176845aaESTs, Weakly similar to cornichon [ M.musculus ]84901123AI059962c,GeneralESTs42351270AI104524Generalheterogeneous nuclearheterogeneous nuclear ribonucleoprotein A/Bribonucleoprotein A/B18582523Y09333k,oacyl-CoA thioesteraseR.norvegicus mRNA for mitochondrial very-long-chain acyl-CoA thioesterase,1, cytosolicacyl-CoA thioesterase 1,18772486X74593n,ccFructose and mannoseSorbitol dehydrogenaseSorbitol dehydrogenasemetabolism7268991AI013541jESTs, Moderately similar to ribonuclease 6 precursor [ H.sapiens ]59071264AI104261hESTs116321215AI102427GeneralESTs, Weakly similar to KIAA0324 [ H.sapiens ]41982220M83143bRat beta-galactoside-alpha 2,6-sialyltransferase mRNA231061337AI145081GeneralESTs, Highly similar to cell division control protein CDC21 [ H.sapiens ]186721576AI178189GeneralESTs, Weakly similar to Kruppel-like transcription factor [ R.norvegicus ], ESTs, Weaklysimilar to OZF RAT ZINC FINGER PROTEIN OZF [ R.norvegicus ]6791571AA945613General,bb,ddESTs15996AA686470j,wDNA-damage inducibleDNA-damage inducible transcript 3transcript 3240491552AI177341GeneralESTs, Highly similar to CGI-10 protein [ H.sapiens ]19038204AA851818nESTs22183520AA943217dEST15907698AA996422General,zESTs64391092AI058436kESTs, Moderately similar to P2CG MOUSE PROTEIN PHOSPHATASE 2C GAMMA ISOFORM[ M.musculus ]82121730AI231807h,q,ccferritin light chain 1ferritin light chain 1201692398X03347c166561612AI179634GeneralESTs, Weakly similar to ankyrin [ R.norvegicus ]19411378AA893667b,vESTs, Moderately similar to AC006978 1 supported by human and rodent ESTs[ H.sapiens ]189101755AI232419yESTs, Weakly similar to YLC4_CAEEL HYPOTHETICAL 81.0 KD PROTEINC35D10.4 IN CHROMOSOME III [ C.elegans ]23500256AA860010m,rESTs159952267S74351eRattus norvegicus protein tyrosine phosphatase mRNA, complete cds391862AA801333aESTs177531242AI103246GeneralESTs, Highly similar to S65568 CCAAT-binding factor CBF2 - mouse[ M.musculus ]6044935AI011285tESTs30911848AI236027aaESTs57231077AI045191GeneralESTs, Weakly similar to FSPO RAT F-SPONDIN PRECURSOR [ R.norvegicus ]15312275AA875126GeneralESTs19322205AA851960pmelanoma antigen,melanoma antigen, family D, 1family D, 15731737AI232087cGlyoxylate and dicar-hydroxyacid oxidase 3hydroxyacid oxidase 3 (medium-chain)boxylate metabolism(medium-chain)256872435X51706w,ccribosomal protein L92423766AA817726uESTs185221347AI145870nESTs169822202M58634eInsulin-like growth factorInsulin-like growth factor binding protein 1binding protein 1212741871AI236726aaESTs6778688AA964763GeneralESTs, Highly similar to DRIM protein [ H.sapiens ]4588771AB009636GeneralRattus norvegicus mRNA for phosphoinositide 3-kinase, complete cds44412466X62146h,ccESTs, Highly similar to 60S RIBOSOMAL PROTEIN L11 [ R.norvegicus ]30731782AI233494mESTs, Weakly similar to I38079 OXA1 homolog [ H.sapiens ]208482446X54617cRat mRNA for myosin regulatory light chain (RLC)6702445X54096ddLecithin-cholesterolLecithin-cholesterol acyltransferaseacyltransferase178095AA686461zribosomal protein L30ribosomal protein L30189571917D00512k,oButanoate metabolism,Acetyl-Co A acetyltrans-Acetyl-Co A acetyltransferase 1, mitochondrialFatty acid biosynthesisferase 1, mitochondrial(path 2), Fatty acidmetabolism, Lysinedegradation, Propanoatemetabolism, Pyruvatemetabolism, Synthesis anddegradation of ketonebodies, Tryptophanmetabolism12248513AA942829aaESTs, Weakly similar to T27118 hypothetical protein Y53C10A.5 - Caenorhabditis elegans[ C.elegans ]6692085K03039iESTs, Rat mRNA for leucocyte-common antigen (L-CA)245902188M35299pSerine protease inhibitor,Serine protease inhibitor, kanzai type 1/Trypsin inhibitor-like protein, pancreatickanzai type 1/Trypsin inhibitor-likeprotein, pancreatic5952661AA963102e,GeneralRattus norvegicus amino acid transporter system A (ATA2) mRNA, complete cds184251686AI230208GeneralESTs, Weakly similar to p58 [ R.norvegicus ]9214467AA925116a,winterferon gamma inducinginterferon gamma inducing factor binding proteinfactor binding protein4314792AF010597g,xATP-binding cassette, sub-ATP-binding cassette, sub-family B (MOR/TAP), member 11family B (MDR/TAP),member 11186182163M24026wRT1 class lb geneRT1 class lb gene19105236AA859230GeneralESTs, Highly similar to HG14 MOUSE NONHISTONE CHROMOSOMAL PROTEINHMG-14 [ M.musculus ]90161152AI070903cEST23005512AA942770wESTs223791725AI231448zESTs, Highly similar to G6PI MOUSE GLUCOSE-6-PHOSPHATE ISOMERASE[ M.musculus ]93221551AI177333aaESTs185071482AI175551d,General,yESTs, Moderately similar to AF145050 1 translation elongation factor 1-delta subunit [ R.norvegicus ]142581676AI229902e,i,GeneralESTs215041327AI137941rESTs1801215AA858636GeneralESTs, Weakly similar to MCM6 RAT DNA REPLICATION LICENSING FACTORMCM6 [ R.norvegicus ]22635675AA964289eESTs171592036J00797Generalalpha-tubulinalpha-tubulin65121843AI235898bbESTs150322382U89905lMethylacyl-CoA racemaseMethylacyl-CoA racemase alphaalpha15007411AA900236GeneralESTs5608113AA819041GeneralESTs97191166AI071722GeneralESTs, Moderately similar to AF151892 1 CGI-134 protein [ H.sapiens ]12094400AA899681k,bb,ccESTs, Weakly similar to 16.7Kd protein [ H.sapiens ]79261050AI043913f,xESTs210941925D10354p,zAlanine and aspartateglutamic-pyruvate trans-glutamic-pyruvate transaminase (alanine aminotransferase)metabolism, Carbonaminase (alanine amino-fixation, Glutamatetransferase)metabolism5141481AA925393eRat mRNA for acetyl-coenzyme A carboxylase (EC 6.4.1.2.) 3′ untranslated region16579645AA957143j,vESTs, Weakly similar to T28060 hypothetical protein ZK863.6 - Caenorhabditis elegans[ C.elegans ]14509618AA955871dESTs6373221AA858726nESTs5742097L13039r,wGlyoxylate andcalpactin I heavy chain,Rattus norvegicus clone BB.1.4.1dicarboxylate metabolismhydroxyacid oxidase 3unknown Glu-Pro dipeptide repeat protein mRNA, complete cds, calpactin I heavy(medium-chain),chain, hydroxyacid oxidase 3 (medium-chain)unknown Glu-Prodipeptide repeat protein1757721AA799566hESTs, Weakly similar to MT18_YEAST DNA REPAIR/TRANSCRIPTIONPROTEIN MET18/MMS19 [ S.cerevisiae ]6992349U55765pRattus norvegicus RASP1 mRNA, complete cds4730412AA900326dESTs192881721AI231305qpdgfPlatelet-derived growthPlatelet-derived growth factor receptor alphafactor receptor alpha85221127AI060071bESTs18841981D50695i,GeneralRattus norvegicus mRNA for proteasomal ATPase (Tat-binding protein7),complete cds21471198AA851343cESTs14393937AI011367yESTs, Highly similar to coded for by human cDNAs W37389 [ H.sapiens ]21772931AI011179h,rimmunoglobulin (CD79A)immunoglobulin (CD79A) binding protein 1binding protein 1118931709AI230951iESTs13332366AA893080b,GeneralESTs77821814AI234515aESTs43812026H33003pESTs204221288AI111858GeneralESTs, Highly similar to I49523 Mouse primary response gene B94 mRNA, 3′ endmouse [ M.musculus ]189581940D13921k,oButanoate metabolism,Acetyl-Co A acetyltrans-Acetyl-Co A acetyltransferase 1, mitochondrialFatty acid biosynthesisferase 1, mitochondrial(path 2), Fatty acidmetabolism, Lysinedegradation, Propanoatemetabolism, Pyruvatemetabolism, Synthesis anddegradation of ketonebodies, Tryptophanmetabolism15982327U30186wDNA-damage inducibleDNA-damage inducible transcript 3transcript 3173012213M69246Generalserine proteinase inhibitor,collagen binding protein 1clade H (heat shock protein47), member 1117981108AI059337ccESTs113821311AI136692GeneralESTs68251088AI045972nESTs12314568AA945596p,q,GeneralESTs, Moderately similar to LECT2 precursor [ H.sapiens ]4486325AA892298cESTs, Weakly similar to matrin cyclophilin [ R.norvegicus ]18952438AA924006hTissue inhibitor ofTissue inhibitor of metalloproteinase 3metalloproteinase 388341348AI145899jESTs, Moderately similar to FLI-LRR associated protein-1 [ M.musculus ]40401622AI179993GeneralESTs, Highly similar to Pax transcription activation domain interacting protein PTIP[ M.musculus ]3934942AI011510eESTs181411555AI177413GeneralOxidative phosphorylation,ATP synthase subunit dATP synthase subunit d, ESTs, Moderately similar to T46317Type III proteinhypothetical protein DKFZp434A0612.1 [ H.sapiens ]242901067AI045040GeneralESTs, Weakly similar to T15251 hypothetical protein K07B1.4 - Caenorhabditis elegans[ C.elegans ]32541929D10756cProteasomeproteasome (prosome,proteasome (prosome, macropain) subunit, alpha type 5macropain) subunit,alpha type 5234691243AI103282aaESTs17962774AB012230Generalnuclear factor I/Bnuclear factor I/B131381783AI233552uESTs10596629AA956405bbESTs23320607AA955164General,bbESTs155792181M33648oRat mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase mRNA, complete cds623699AA818627f,g,yEST, Moderately similar to ISI1 RAT INSULIN-INDUCED PROTEIN 1[ R.norvegicus ]66331654AI228931xESTs261901183AI072578y76671766AI233687nESTs, Weakly similar to T46906 hypothetical protein DKFZp761D0223.1 [ H.sapiens ]139321711AI230988b,m,General,yESTs193922397X02918a,tArginine and prolineProtein disulfideProtein disulfide isomerase (Prolyl 4-metabolismisomerase (Prolyl 4-hydroxylase, beta polypeptide)hydroxylase, beta poly-peptide)10695132AA819679eESTs207042169M26127f,g,h,q,cc,ddFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily I (aromaticTryptophan metabolismfamily I (aromaticcompound-inducible), member A2 (Q42, form d)compound-inducible),member A2 (Q42, form d)14752103L16764cHeat shock protein 70-1ESTs, Highly similar to S10A RAT S-100PROTEIN, ALPHA CHAIN [ R.norvegicus ], Heat shock protein 70-122725416AA900506nESTs, Highly similar to TS24 MOUSE PROTEIN TSG24 [ M.musculus ]175412168M26125h,x,ccEpoxide hydrolase 1Epoxide hydrolase 1 (microsomal xenobiotic hydrolase)(microsomal xenobiotichydrolase)215862516X97772GeneralGlycine, serine and3-phosphoglycerate3-phosphoglycerate dehydrogenasethreonine metabolismdehydrogenase125511680AI230056c,m,General,uESTs175291423AI171460zESTs, Weakly similar to amyloid beta-peptide binding protein [ R.norvegicus ]21848656AA957896kmitogen activated proteinmitogen activated protein kinase kinasekinase kinase 24511534AA944348p,GeneralESTs140831549AI177181dESTs, Weakly similar to T18290 FYVE finger-containing phosphoinositide kinasemouse [ M.musculus ]3723971AI012599ddESTs115461481AI175535GeneralESTs, Moderately similar to putative oncogene protein [ H.sapiens ]19319311AA891937iESTs, Highly similar to S66254 dolichyl-diphosphooligosaccharide-protein glycotransferase [ H.sapiens ]20088343AA892666b,gESTs5241499AA925986lESTs161241537AI176963lRattus norvegicus transcription factor MRG1 mRNA, complete cds155992487X75253e,p,tphosphatidylethanolaminephosphatidylethanolamine binding proteinbinding protein382826AF080507GeneralMannose binding proteinMannose binding protein A, serumA, serum2367838AF095741nRattus norvegicus MG87 mRNA, complete cds175322059J03867GeneralAminosugars metabolismHHs:diaphorase (NADH)Rat NADH-cytochrome b-5 reductase mRNA, complete cds(cytochrome b-5reductase)124372030H33686jESTs, Moderately similar to SYC_HUMAN CYSTEINYL-TRNASYNTHETASE [ H.sapiens ]163102098L13600x,ddRattus norvegicus glycine transporter mRNA, complete cds121911959D26073vphosphoribosylpyro-phosphoribosylpyrophosphate synthetase-phosphate synthetase-associated protein (39 kDa)associated protein(39 kD5264504AA926107rESTs, Highly similar to RGS3 RATREGULATOR OF G-PROTEIN SIGNALING 3 [ R.norvegicus ]44281420AI171362bbOxidative phosphorylation,HHs:NADH dehydrogenaseESTs, Moderately similar toUbiquinone(ubiquinone) Fe-SNUAM_HUMAN NADH-UBIQUINONEbiosynthesisprotein 1 (75kD)OXIDOREDUCTASE 75 KD SUBUNIT PRECURSOR [ H.sapiens ](NADH-coenzyme Qreductase)78931047AI043761iEST94981194AI073164c,vsecretory carriersecretory carrier membrane protein 1membrane protein 1158601234AI102868mESTs, Weakly similar to phosphoserine aminotransferase [ H.sapiens ]201532084K02817fAsialoglycoproteinAsialoglycoprotein receptor 1 (hepatic lectin)receptor 1 (hepaticlectin)153981865AI236566GeneralESTs, Moderately similar to T12473hypothetical protein DKFZp564G1762.1 [ H.sapiens ]77761009AI028963GeneralESTs17897381AA893905d,eESTs5702498X82445rnuclear distributionnuclear distribution gene C homolog (Aspergillus)gene C homolog(Aspergillus)88561179AI072402oESTs, Moderately similar to KRAB-zinc finger protein KZF-2 [ R.norvegicus ]204482431X17053iSmall inducible gene JESmall inducible gene JE123651623AI180013dRat MHC class I IgG Fc region receptor large subunit p51 (FcRn) mRNA,complete cds98001169AI072014GeneralESTs, Weakly similar to AF165892 1 RNA binding protein SiahBP [ R.norvegicus ]138991691AI230424GeneralESTs13862094L08505idynein, cytoplasmic,dynein, cytoplasmic, heavy chain 1heavy chain 146501206AI101582GeneralESTs, Weakly similar to T26236 hypothetical protein W06D4.4 -Caenorhabditis elegans [ C.elegans ]55411286AI111707iESTs6985927AI010862hEST58741345AI45801GeneralESTs220231799AI233822i,ESTs91661317AI137406mESTs119371314AI137218GeneralESTs18882017E13573lRat brain mRNA for neuronal death protein, complete cds105441982D63411c,rRattus norvegicus outer mitochondrial membrane receptor rTOM20 mRNA,complete cds25571525AI176820vESTs22667552AA945069cESTs208592235M92074bbtroponin I, cardiactroponin I, cardiac4107391AA899109General,yESTs68912347U53922nDnaJ-like proteinDnaJ-like protein254002140M14776h,n,x14621242AA859529bbdiacylglyceroldiacylglycerol acyltransferaseacyltransferase5497825AF080468g,bb,ddglucose-6-phosphatase,glucose-6-phosphatase, transport protein 1transport protein 117642499X83399ddR.norvegicus mRNA eIF-4E25170800AF030087cc231711685AI230190idamage-specific DNAdamage-specific DNA binding protein 1binding protein 1237111505AI176376tATPase Na+/K+trans-ATPase Na+/K+ transporting beta 1 polypeptideporting beta 1 polypeptide137621688AI230326mESTs20808195AA851281ddESTs, Weakly similar to JC4230 ribosomal protein L7 - rat [ R.norvegicus ]175911419AI1721354cESTs192711727AI231566x,aaESTs, Highly similar to MAX RAT MAX PROTEIN [ R.norvegicus ]168981382AI170249GeneralESTs, Highly similar to similar to nitrogen permease regulator [ H.sapiens ]15471251AA859869h26S proteasome, subunit26S proteasome, subunit p112p11244392AA685175uESTs, Weakly similar to ES/130-related protein [ H.sapiens ]805891AA818475rESTs138741674AI229832GeneralESTs, Weakly similar to KIAA0859 protein [ H.sapiens ]401787AA818287aESTs27441994D87991wESTs, Highiy similar to JC5026 UDP-galactose transporter related protein 1 - rat[ R.norvegicus ]4491108AA818798iRattus norvegicus mRNA for cathepsin Y, partial cds119041989D85183b,wProtein tyrosineProtein tyrosine phosphatase, non-receptor type substrate 1 (SHP substratephosphatase, non-receptortype substrate 1 (SHP1)substrate 1)61071935D13122d,iATPase inhibitor (ratATPase inhibitor (rat mitochondrial IF1 protein)mitochondrial IF1 protein)15721592AI178828uRattus norvegicus Sprague/Dawley PHAS I mRNA, complete cds11191979AI013042GeneralESTs, Moderately similar to SRE1_HUMAN STEROLREGULATORY ELEMENT BINDING PROTEIN-1 [ H.sapiens ]12734934AI011208bESTs1291758AB000491cfor proteasomal ATPasefor proteasomal ATPase (SUG1)(SUG1)18432182M33962y,aaProtein-tyrosineProtein-tyrosine phosphatasephosphatase143901753AI232385nESTs78722231M86912d,eEST21748181AA850777GeneralESTs15743699AA996434qphosphatidylinositolphosphatidylinositol 3-kinase3-kinase234452227M84719xFlavin-containingFlavin-containing monooxygenase 1monooxygenase 1146511846AI235919ddESTs17289302AA891785zCitrate cycle (TCAHMm:isocitrate dehydro-ESTs, Weakly similar to IDHC RATcycle), Glutathionegenase 2 (NADP+),ISOCITRATE DEHYDROGENASE [ R.norvegicus ]metabolism, Reductivemitochondrialcarboxylate cycle (CO2fixation)210112024H32189x,ddGlutathioneGlutathione-S-transferase,Glutathione-S-transferase, mu type 2 (Yb2)metabolismmu type 2 (Yb2)17734747AA998683jHeat shock 27 kDa proteinESTs, Heat shock 27 kDa protein1682523AA943555hlinker of T-cell receptorlinker of T-cell receptor pathwayspathways216572463X61381a,e,wRattus norvegicus interferon-inducible protein varient 10 mRNA,complete cds17573983AI013132vRattus norvegicus membrane- and microfilament-associated protein p58 mRNA,complete cds40011213AI02070GeneralESTs243211748AI232340e,nStromal cell-derivedStromal cell-derived factor 1factor 15384288AA891041n,vjun B proto-oncogenejun B proto-oncogene601383AA818144tC-reactive proteinC-reactive protein97541294AI112194c,zESTs176762391V01235n,xFatty acid bindingFatty acid binding protein 1, liverprotein 1, liver17524921AI010568cGrowth hormone receptorGrowth hormone receptor11960300AA891740lESTs, Weakly similar to EPOR RATERYTHROPOIETIN RECEPTOR PRECURSOR [ R.norvegicus ]36451835AI235362fESTs, Highly similar to NOF1 [ H.sapiens ]129641857AI236227zESTs187501978D45250wprotease (prosome,protease (prosome, macropain) 28 subunit, betamacropain) 28 subunit,beta210532143M15481f,tRat insulin-like growth factor-I mRNA, 3′ end149101564AI177631GeneralESTs, Moderately similar to myosin-binding C-protein [ R.norvegicus ]3963435AA923955jESTs88981259AI103957d,eCD81 antigen (target ofCD81 antigen (target of antiproliferative antibody 1)antiproliferativeantibody 1)2799998AI013778c,uESTs9572367U72741tLectin, galactose binding,Lectin, galactose binding, soluble 9 (Galectin-9)soluble 9 (Galectin-9)8622357U62940kstress-inducible chaperonestress-inducible chaperone mt-GrpE#1mt-GrpE#119067248AA859663GeneralESTs124821336AI144965qESTs, Weakly similar to T34021 protein kinase SK2 - rat [ R.norvegicus ]3562260S66024g,GeneralCAMP responsive elementCAMP responsive element modulatormodulator, transcriptionalrepressor CREM6062484X71898jurinary plasminogenurinary plasminogen activator receptor 2activator receptor 25360950AI011763Generalalpha actinin 4alpha actinin 459951759AI232565GeneralESTs23512608AA955282n,GeneralESTs18421572AA945617GeneralESTs, Highly similar to nitrilase hormolog 1 [ M.musculus ]25361518AI176616e,m,qESTs222131822AI234858GeneralESTs, Highly similar to KIAA0017 protein [ H.sapiens ]17832960AI012182GeneralRat major beta-globin mRNA, complete cds13212120L37333gGalactose metabolism,Glucose-6-phosphataseGlucose-6-phosphataseGlycolysis/Gluconeogenesis,Starch and sucrosemetabolism105031957D21215d,hcoagulation factor Xcoagulation factor X190402055J03627xS-100 related protein,S-100 related protein, clone 42Cclone 42C1454553AA800456rESTs4250101AA818700vESTs70841689AI230362qESTs, Moderately similar to T46458 hypothetical protein DKFZp434M102.1[ H.sapiens ]11424928AI010936bESTs, Moderately similar to PTN3_HUMAN PROTEINTYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 3 [ H.sapiens ]16412014E03428m,v,wPeptidylglycine alpha-Peptidylglycine alpha-amidating monooxygenaseamidating monooxygenase101531102AI059110ddEST223111492AI176007t,aaESTs, Highly similar to PM5P_HUMANPROTEIN PM5 PRECURSOR [ H.sapiens ]123581395AI170661rRAS p21 proteinRAS p21 protein activator 3activator 323312309AA891920iESTs, Weakly similar to A Chain A, Nuclear Transport Factor 2[ R.norvegicus ]18085212AA858603rEST, Weakly similar to T16084 hypothetical F16H11.1 -Caenorhabditis elegans [ C.elegans ]19254794AF014009dMethane metabolism,HMm:peroxiredoxin 5Rattus norvegicus mRNA for thiol-specificPhenylalanine metabolismantioxidant protein (1-Cys peroxiredoxin)19069525AA943737e,jendothelial differ-endothelial differentiation sphingolipid G-entiation sphingolipidprotein-coupled receptor 1G-protein-coupled recep34671894AI237835n,General,aaESTs, Moderately similar to MXI1 RAT MAX INTERACTING PROTEIN 1[ R.norvegicus ]82151431AI171692m,Generalferritin light chain 1Rattus norvegicus kynurenineaminotransferase/glutamine transaminase K (Kat) gene, complete cds,ferritin light chain 13882910AI010191aESTs, Highly similar to serine/threonine kinase [ R.norvegicus ]158722117L28135t,u,wSolute carrier family 2Solute carrier family 2 A2 (gkucose transporter, type 2)A2 (gkucose transporter,type 2)216041004AI013913GeneralESTs19575182AA850814yESTs, Moderately similar to AF151807 1 CGI-49 protein [ H.sapiens ]236121400AI170751gESTs238842214M73714kArginine and prolinealcohol dehydrogenasealcohol dehydrogenase family 3, subfamilymetabolism, Ascorbatefamile 3, subfamily A2A2and aldarate metabolism,Bile acid biosynthesis,Butanoate metabolism,Fatty acid metabolism,Glycerolipid metabolism,Histidine metabolism,Lysine degradation,Propanoate metabolism,Pyruvate metabolism,Tryptophan metabolism,Valine, leucine andisoleucine degradation,beta-Alanine metabolism32561370AI69479d,GeneralProteasomeproteasome (prosome,proteasome (prosome, macropain) subunit, alpha type 5macropain) subunit,alpha type 52691694AA965075GeneralESTs15914723AA997711GeneralESTs164272156M21354dprocollagen, type III,procollagen, type III, alpha 1137821570AI177848GeneralESTs4312773AB010635l,General,x,zRattus norvegicus mRNA for carboxylesterase precursor, complete cds1615015AA799489k,oFatty acid metabolismacyl-coA oxidaseacyl-coA oxidase216601375AI169751General,wRattus norvegicus interferon-inducibleprotein variant 10 mRNA, complete cds179031713AI231083n,aaESTs, Moderately similar to AF155103 1NY-REN-25 antigen [ H.sapiens ]15832296U07201m,yAsparagine synthetaseAsparagine synthetase184171683AI230166aESTs67431719AI231219d,GeneralESTs21916992AI013627eRattus norvegicus DAD-1 gene481950D17310bbRat 3-alpha-hydroxysteroid dehydrogenase (3-alpha-HSD) mRNA, complete cds219751453AI172247bPurine metabolismxanthine dehydrogenasexanthine dehydrogenase15980261AA866426zESTs183022332U33500nRattus norvegicus retinol dehydrogenase type II mRNA, complete cds2103189AA851135zRattus norvegicus ribosomal protein S271 (S27-1) mRNA, complete cds3145712AA997237yESTs17549348AA892776k,GeneralRat mitochondrial proton/phosphate symporter mRNA, complete cds7982338U38253yRattus norvegicus initiation factor eIF-2Bgamma subunit (eIF-2B gamma) mRNA, complete cds159972287U02553eRattus norvegicus protein tyrosine phosphatase mRNA, complete cds180002313U19485tRattus norvegicus spp-24 precursor mRNA, partial cds180021041AI043655i,j,v,z,aaRattus norvegicus spp-24 precursor mRNA, partial cds59671218AI102520wESTs, Moderately similar to AF161588 1GABA-A receptor-associated protein [ R.norvegicus ]183931697AI230632cESTs3993484AA925540lESTs17849414AA900460d,GeneralESTs, Weakly similar to TCPA RAT T-COMPLEX PROTEIN 1, ALPHA SUBUNIT [ R.norvegicus ]42721722AI231309k,oESTs, Moderately similar to AF153605 1androgen induced protein [ H.sapiens ]24091653AA957612aEST23031665AA963661eESTs74201016AI029291kESTs, Highly similar to CIpX-like protein [ H.sapiens ]22619904AI009825mESTs26123860AI008396General23322351AA892821g,xRattus norvegicus aiar mRNA forandrogen-inducible aldehyde reductase, complete cds207162237M94548a,h,tFatty acid metabolism,cytochrome P450 4F1cytochrome P450 4F1Tryptophan metabolism129991502AI167276jESTs, Highly similar to UAP1_HUMANUDP-N-ACETYLHEXOSAMINE PYROPHOSPHORYLASE [ H.sapiens ]1159313AA891949GeneralESTs240192489X77235jADP-ribosylation-like 4ADP-ribosylation-like 474272070J05122uBenzodiazepin receptorBenzodiazepin receptor (peripheral)(peripheral)6121146AA848573pESTs, Highly similar to H4_HUMAN HISTONE H4 [ R.norvegicus ]184731353AI168975xESTs432110L23413Generalsulfate anionsulfate anion transportertransporter6919917AI010461o,General,yESTs114311853AI236120j,aaESTs16173642AA957003wRattus norvegicus intercellular calcium-binding protein (MRP8) mRNA, complete cds17489970AI012566bbunconventional myosinunconventional myosin Myr2 I heavy chainMyr2 I heavy chain187041425AI171562ddnuclear protein E3-3 orf1nuclear protein E3-3 orf123321351AA892821f,m,uRattus norvegicus aiar mRNA forandrogen-inducible aldehyde reductase complete cds9062378U83112lforkhead box M1forkhead box M1229581422AI171374jESTs, Moderately similar to meningioma-expressed antigen 11 [ H.sapiens ]2330676AA964292GeneralEST13541971D38065f,l,xAndrogen and estrogenUDP-glucuronosyltrans-Rattus norvegicus cytoplasmic dyneinmetabolism, Pentose andferase 1 family,intermediate chain 2C mRNA, completeglucuronate interconver-member 1cds, UDP-glucuronosyltransferase 1sions, Porphyrin andfamily, member 1chlorophyll metabolism,Starch and sucrosemetabolism58241082AI045555f,lESTs197831605AI179388gESTs, Weakly similar to T24789hypothetical protein T10C6.5 - Caenorhabditis elegans [ C.elegans ]2682362U67908General,bbChymase 1, mast cellChymase 1, mast cell20988418AA900562jESTs201231173AI072214c,d,General,uESTs, Weakly similar to T26686hypothetical protein Y38F1A.6 - Caenorhabditis elegans [ C.elegans ]23192289AA891107p,r,GeneralRattus norvegicus diphosphoinositolpolyphosphate phosphohydolase type II (Nudt4) mRNA, complete cds51971246AI103376mESTs, Weakly similar to T31650hypothetical protein Y57A10A.cc -Caenorhabditis elegans [C.elegans]21462194AA851261GeneralESTs, Weakly similar to A61382 phosphorylation regulatory protein HP-10[ H.sapiens ]115041429AI171652bESTs15081234AA859218GeneralESTs6826888AI009493d,GeneralESTs114031412AI171088dspermidine synthasespermidine synthase155511704AI230759nESTs, Moderately similar to ornithine decarboxylase antizyme 2 [M.musculus]14033978AI012979aaESTs151911508AI176456b,gRat metallothionein-2 and metallothionein-1 genes, complete cds242342359U63923d,GeneralPyrimidine metabolismthioredoxin reductase 1thioredoxin reductase 158731084AI045767GeneralESTs18168516AA942995zESTs, Highly similar to T50630 hypothetical protein DKFZp762N0610.1[ H.sapiens ]219042164M24239h,q,x,cc,dd11251984D82071g,GeneralProstaglandin andprostaglandin D2prostaglandin D2 synthase 2, hematopoieticleukotriene metabolismsynthase 2,hematopoietic12662273S80631mRat ig epsilon heavy chain, complete coding region and 3′ ut, mma17353852AI008020bbRat cytosolic malic enzyme mRNA, 3′ flank34041966D30740c14 - 3 - 3 - zetaTyrosine 3-monooxygenase/tryptophan 5-isoform, Tyrosine 3-monooxygenase activation protein, zeta polypeptidemonooxygenase/tryptophan5-monooxygenase activationprotein, zeta polypeptide59531416AI171231GeneralRattus norvegicus amino acid transportersystem A (ATA2) mRNA, complete cds90791157AI071251gESTs22081543AA944818General,aaESTs162671261AI103977i,jESTs, Highly similar to I39358 heterogeneous nuclear ribonucleoprotein H[ H.sapiens ]235471521AI176734GeneralESTs, Weakly similar to T22286hypothetical protein F46B6.3 - Caenorhabditis elegans [ C.elegans ]165181511AI176546oESTs, Moderately similar to HS9B RATHEAT SHOCK PROTEIN HSP 90-BETA [ R.norvegicus ]1669624AA799607ccESTs100931096AI058746ccESTs62911335AI144797GeneralESTs250702281S83279k,oAndrogen and estrogenperoxisomal multifunc-peroxisomal multifunctional enzyme type IImetabolismtional enzyme type II10985112AA818998GeneralESTs, Weakly similar to HP33 [ R.norvegicus ]43171161AI071531iRattus norvegicus mRNA for endothelialreceptor for oxidized low-density lipoprotein, complete cds3265728AA997784c,mEST3242719AA997596GeneralESTs167811815AI234527p,GeneralGlutathione metabolismHMm:glutathione S-ESTs, Highly similar to XURT8C glutathione transferase (EC 2.5.1.18)8,transferase, alpha 4cytosolic - rat [ R.norvegicus ]238741250AI103556g,GeneralESTs, Highly similar to CKS1_HUMANCYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 [ M.musculus ]13942336U37099lRattus norvegicus GTP-binding protein (rab 3C) mRNA, complete cds1597795AF014503tRattus norvegicus p8 mRNA, complete cds227471437AI171832GeneralESTs, Moderately similar to AF151848 1 CGI-90 protein [ H.sapiens ]195901992D87336rESTs, Highly similar to BLMH RATBLEOMYCIN HYDROLASE [ R.norvegicus ]243681630AI180392dESTs, Highly similar to AF114169 1 nucleotide-binding protein short form[ M.musculus ]114161452AI172185c,General,wESTs, Highly similar to NOF 1 [ H.sapiens ]79161049AI043855GeneralSterol biosynthesisHMm:sterol-C5-desaturaseRattus norvegicus C5D mRNA for sterol(fungal ERG3, delta-5-C5-desaturase, complete cdsdesaturase) homolog[ S.cerevisae ]186062443X53504w,ccESTs, Highly similar to 60S RIBOSOMALPROTEIN L12 [ R.norvegicus ]195842417X13905vESTs, Moderately similar to RB1A RATRAS-RELATED PROTEIN RAB-1A [ R.norvegicus ]126062204M59861General,u,ccOne carbon pool10-formyltetrahydro-10-formyltetrahydrofolate dehydrogenaseby folatefolate dehydrogenase3362736AA998092zEST21231673AI229746ddESTs, Weakly similar to CD53 RATLEUKOCYTE SURFACE ANTIGEN CD53 [ R.norvegicus ]206012438X52625d,rButanoate metabolism,3-hydroxy-3-methyl-3-hydroxy-3-methylglutaryl-Coenzyme ASynthesis and degradationglutaryl-Coenzyme Asynthase 1of ketone bodies, Valine,synthase 1leucine and isoleucinedegradation250912476X65190a14353244AA859585cESTs66281591AI178793pESTs, Highly similar to MAN2 RATALPHA-MANNOSIDASE II [ R.norvegicus ]5152474X63854i,vTransporter 2, ABCTransporter 2, ABC (ATP binding cassette)(ATP binding cassette)22187521AA943229aEST149962426X16038m,r,yFolate biosynthesis,Tissue-nonspecific ALPTissue-nonspecific ALP alkaline phosphataseGlycerolipid metabolismalkaline phosphatase11141019AI029917bRat brain neuron-specific enolase mRNA, complete cds60331769AI233081mESTs166501975D42137rAnnexin VAnnexin V242111287AI1111853bESTs, Highly similar to H33_HUMAN HISTONE H3.3 [ R.norvegicus ]68161249AI103458GeneralESTs, Weakly similar to T22612hypothetical protein F54B3.3 -Caenorhabditis elegans [ C.elegans ]17333312AA891940ddESTs, Highly similar to RHOC MOUSETRANSFORMING PROTEIN RHOC [ M.musculus ]16216611AA955392GeneralESTs8860583AA945915GeneralESTs17359850AI007981pESTs, Moderately similar to AC004882 5similar to cytochrome Bc1 J chain [ H.sapiens ]4207567AA945591o,uESTs, Weakly similar to JC5105 stromalcell-derived factor 2 - mouse [ M.musculus ]597975AA817990GeneralESTs45731611AI179613xArginine and prolineGlutamate dehydrogenaseGlutamate dehydrogenasemetabolism, D-Glutamine and D-glutamatemetabolism, Glutamatemetabolism, Nitrogenmetabolism, Urea cycleand metabolism of aminogroups164492241M95591GeneralSterol biosynthesis,famesyl diphosphatefamesyl diphosphate famesyl transferase 1Terpenoid biosynthesistransferase 125321513AI76590bESTs, Weakly similar to S68418 proteinphosphatase 1 M chain M110 isoform - [ R.norvegicus ]50461895AI237855c,ddESTs3095709AA997077bESTs, Moderately similar to 3′-5′exonuclease TREX1 [ M.musculus ]199931407AI170777Generalmitochondrial aconitasemitochondrial aconitase (nuclear aco2 gene)(nuclear aco2 gene)39161378AI169947d,uESTs21812718AA997588bbESTs, Weakly similar to T23657 hypothetical protein M0F1.6 -Caenorhabditis elegans [ C.elegans ]4917443AA924140GeneralESTs, Weakly similar to Y193_HUMANHYPOTHETICAL PROTEIN KIAA0193 [ H.sapiens ]4134192AA851240p,GeneralESTs12766968AI012505GeneralESTs, Weakly similar to AC004876 5similar to predicted proteins AAB54240 [ H.sapiens ]6547959AI012181rESTs, Highly similar to S65755tetrahydrofolylpolyglutamate synthase [ M.musculus ]188671995D88250e,qRattus norvegicus mRNA for serine protease, complete cds208622009E01415General,wGlitathione metabolismglutathione S-trans-glutathione S-transferase, mu type 3 (Yb3)ferase, mu type 3 (Yb3)15492075J05519tFolate biosynthesis,C1-tetrahydrofolateC1-tetrahydrofolate synthaseGlyoxylate and dicarboxy-synthaselate metabolism, Onecarbon pool by folate204312275S81448GeneralAndrogen and estrogenSteroid-5-alpha-reductase,Steroid-5-alpha-reductase, alphametabolism, Bilealpha polypeptide 1 (3-polypeptide 1 (3-oxo-5 alpha-steroid deltabiosynthesisoxo-5 alpha-steroid delta4-dehydrogenase alpha 1)4-dehydrogenase alpha 1)3149384AA894030oESTs73811013AI029132zESTs, Moderately similar to Similar toS.cerevisiae hypothetical protein L311 [ H.sapiens ]214002190M36410GeneralFolate biosynthesissepiapterin redustasesepiapterin reductase25137763AB005540c112281235AI102871kESTs152181216AI102495GeneralESTs, Moderately similar to purine nucleoside phosphorylase [ M.musculus ]23163480AA925328GeneralESTs, Moderately similar to G01251 Rar protein [ H.sapiens ]167681948D16478k,oRat mRNA for mitochondrial long-chainenoyl-CoA hydratase/3-hydroxyacyl-CoAdehydrogenase alpha-subunit ofmitochondrial trifunctional protein,complete cds35161472AI175064General,aaESTs156851803AI233870r,GeneralESTs, Weakly similar to 100K RAT 100 KD PROTEIN [ R.norvegicus ]23847637AA956723GeneralEST23566612AA955482bbESTs, Moderately similar to AF132950 1 CGI-16 protein [ H.sapiens ]322115L27651dsolute carrier family 22Rattus norvegicus liver-specific transport(organic anion trans-protein mRNA, complete cdsporter), member 723802635AA956535jESTs, Highly similar to similar to human Sua1 [ M.musculus ]21354401AA899721k,oESTs897733AA799741zESTs, Moderately similar to putative ATP-dependent mitochondrial RNA helicase [ H.sapiens ]18891452AA924598k,oESTs21672303AA891789GeneralESTs, Highly similar to Sid393p [ M.musculus ]207812381U89282rtelomerase proteintelomerase protein component 1component 116465428AA901042n,GeneralESTs15711823AF077354aRattus norvegicus ischemia responsive 94kDa protein (irp94) mRNA, complete cds9591973D38072vRat mRNA for protein tyrosine phosphatase, complete cds11080197AA851330nESTs, Moderately similar to erythroblastmacrophage protein EMP [ H.sapiens ]19501179AA850601fESTs144921023AI030091cESTs143321909AJ001044zprotein phosphatase 1,protein.phosphatase 1, regulatoryregulatory (inhibitor)(inhibitor) subunit 5subunit 5132861035AI030790jESTs217851550AI177312zESTs6135115AA819065eESTs13351355AI169105GeneralESTs, Weakly similar to PON1 RATSERUM PARAOXONASE/ARYLESTERASE 1 [ R.norvegicus ]11324691AA964832l,GeneralESTs4115868AI008890GeneralESTs15175565AA945583k,GeneralButanoate metabolism,hydroxyacyl-Coenzyme Ahydroxyacyl-Coenzyme A dehydrogenase,Fatty acid biosynthesisdehydrogenase, type IItype II(path 2), Fatty acidmetabolism, Lysinedegradation, Tryptophanmetabolism, Valine,leucine and isoleucinedegradation16700866AI008838cESTs, Weakly similar to LONN_HUMANMITOCHONDRIAL LON PROTEASE HOMOLOG PRECURSOR [ H.sapiens ]7132507X91234wAndrogen and estrogen17-beta hydroxysteroid17-beta hydroxysteroid dehydrogenase type 2metabolismdehydrogenase type 2118301598AI179093r,GeneralRattus norvegicus diphosphoinositolpolyphosphate phosphohydolase type II (Nudt4) mRNA, complete cds136971520AI176718GeneralESTs84571121AI059835qESTs4882005E00717g,q,cc,ddFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily I (aromaticTryptophan metabolismfamily I (aromaticcompound-inducible), member A1 (C6, form c)compound-inducible),member A1 (C6, form c)18532414X12367fGlutathione metabolismGlutathione peroxidase 1ESTs, Glutathione peroxidase 1225112158M22670m,uAlpha-2-macroglobulinAlpha-2-macroglobulin10016827AF083269uActin-related proteinActin-related protein complex 1bcomplex 1b19775420AA900590ddESTs100711900AI639058uESTs, Moderately similar to dJ718J7.1 [ H.sapiens ]98891060AI044621k,p,aaESTs231371141AI070408jESTs13732112L24907rRattus norvegicus CaM-like protein kinase mRNA, complete cds170642514X95986bbProstaglandin andcarbonyl reductasecarbonyl reductaseleukotriene metabolism48681403AI170763nESTs125561629AI180376xESTs, Weakly similar to Y310_HUMANHYPOTHETICAL PROTEIN KIAA0310 [ H.sapiens ]6536305AA891834rESTs3910389AA894345iESTs, Weakly similar to I59337 mammarytransforming protein - mouse [ M.musculus ]20911406AA899901nESTs, Weakly similar to T14171 ataxin-2 - mouse [ M.musculus ]139591869AI236696tESTs2179138AA848270zESTs, Weakly similar to T13576hypothetical protein EG:52C10.5 - fruit fly [ D.melanogaster ]94221189AI072888aESTs256752419X14181h,w151261986D83796f,g,h,k,ccAndrogen and estrogenUDP-glucuronosyltrans-Rattus norvegicus UDP-metabolism, Pentose andferase 1 family,glucuronosyltransferase UGT1A7 mRNA,glucuronate interconver-member 1complete cds, UDP-glucuronosyltransferase 1sions, Porphyrin andfamily, member 1chlorophyll metabolism,Starch and sucrosemetabolism81321124AI060050GeneralESTs, Highly similar to NGP_HUMANAUTOANTIGEN NGP-1 [ H.sapiens ]186861920D00729k,oFatty acid metabolismdodecenoyl-Coenzyme ARat mRNA for delta3, delta2-enoyl-CoAdelta isomerase (3,2isomerase, dodecenoyl-Coenzyme A deltatrans-enoyl-Coenyme Aisomerase (3,2 trans-enoyl-Coenyme A isomerase)132832128M11266uArginine and prolineOrnithine carbamoyl-Ornithine carbamoyltransferasemetabolism, Urea cycletransferaseand metabolism of aminogroups72191767AI232900Generalperoxiredoxin 4peroxiredoxin 421229859AI008371aaESTs238722151M18416GeneralEarly growth response 1Early growth response 173621011AI029026n,GeneralESTs11162856AI008183zESTs, Weakly similar to ENT1_RATEQUILIBRATIVE NUCLEOSIDETRANSPORTER 1 (EQUILIBRATIVENITROBENZYLMERCAPTOPURINERIBOSIDE-SENSITIVE NUCLEOSIDETRANSPORTER) (EQUILIBRATIVENBMPR-SENSITIVE NUCLEOSIDETRANSPORTER) (NUCLEOSIDETRANSPORTER, ES-TYPE)[ R.norvegicus ]5110476AA925274b,GeneralESTs, Highiy similar to CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY CHAIN [ R.norvegicus ]238361276AI105088GeneralESTs242561641AI228256aaESTs126981397AI170665zESTs162042407X06423h,wribosomal protein S8ribosomal protein S817382213AA858607ccESTs22545898AI009747tESTs9562107L21711g,tLectin, galactoseLectin, galactose binding, soluble 9binding, soluble 5(Galectin-9)(Galectin-5), Lectin,galactose binding,soluble 9 (Galectin-9)25204826AF080507d,e168791363AI169284mESTs, Highly similar to Y069_HUMANHYPOTHETICAL PROTEIN KIAA0069 [ H.sapiens ]20523306AA891842h,iESTs54881670AI229684GeneralESTs, Weakly similar to SE34_YEASTTRNA-SPLICING ENDONUCLEASESUBUNIT SEN34 (TRNA-INTRON ENDONUCLEASE) [ S.cerevisiae ]176181875AI236786GeneralESTs, Weakly similar to FKB1 RAT FK506BINDING PROTEIN [ R.norvegicus ]176341915AJ223355vRattus norvegicus mRNA for mitochondrial dicarboxylate carrier24251619AA955887tESTs11256581AA945898aaESTs189902265S72506GeneralGlutathione metabolismGlutathione-S-transfer-Glutathione-S-transferase, alpha-type (Yc?)ase, alpha type (Yc?)25871738AI232103r,GeneralESTs258521896AI638998n178052294U06274x,bbUDP-glucuronosyltrans-UDP-glucuronosyltransferaseferase6615514AA942889uESTs, Weakly similar to T26686hypothetical protein Y38F1A.6 - Caenorhabditis elegans [ C.elegans ]6957924AI010707bEST, Moderately similar to S12207 hypothetical protein [ M.musculus ]1279758AA800790uESTs22515419AA900582u,wAlpha-2-macroglobulinAlpha-2-macroglobulin89842095L10652c,rinitiation factor 2initiation factor 2 associated 67 kDaassociated 67 kDaproteinprotein57121075AI045154zESTs, Moderately similar to originrecognition complex subunit 5 homolog [ H.sapiens ]4318766AB005900uRattus norvegicus mRNA for endothelialreceptor for oxidized low-density lipoprotein, complete cds20741828AF084186rnoerythroid alpha-noerythroid alpha-spectrin 2spectrin 282741105AI059270vESTs, Weakly similar to hypothetical protein [ H.sapiens ]113011312AI136709qESTs22961303AI112979GeneralESTs, Highly similar to SAP3 MOUSEGANGLIOSIDE GM2 ACTIVATOR PRECURSOR [ M.musculus ]593064AA817688GeneralESTs1832719AA799537vESTs171192321U25746iRattus norvegicus RNA helicase witharginine-serine-rich domain mRNA, complete cds95911587AI178769aRattus norvegicus mRNA for proliferationrelated acidic leucine rich protein PAL31, complete cds235151608AI179498g,GeneralESTs, Highly similar to S23B_HUMANPROTEIN TRANSPORT PROTEINSEC23 HOMOLOG ISOFORM B [ H.sapiens ]22952353AA892831gESTs, Highly similar to 26S proteasome subunit p44.5 [ H.sapiens ]16085267AA874889nESTs175172096L12383GeneralADP-ribosylation factor 4ADP-ribosylation factor 4247792058J03863rRat serine dehydratase (SDH2) mRNA, complete cds56841069AI045056gESTs236512138M14656wSialoprotein (osteopontin)Sialoprotein (osteopontin)17933308AA891916kmembrane interactingmembrane interacting protein of RGS16protein of RGS1616019862AI008498xbrain expressed X-linked 3brain expressed X-linked 376971534AI176942cESTs8992334U35245mvacuolar protein sortingvacuolar protein sorting homolog r-vps33bhomolog r-vps33b70471414AI171172bESTs, Highly similar to I48724 zinc fingerprotein PZF - mouse [ M.musculus ]245962427X16044vProtein phosphatase 2Protein phosphatase 2 (formerly 2A),(formerly 2A), catalyticcatalytic subunit, beta isoformsubunit, beta isoform9136292AA891226GeneralESTs, Highly similar to PRCE RATPROTEASOME EPSILON CHAIN PRECURSOR [ R.norvegicus ]3062749AA998857d,j,pRattus norvegicus mRNA for pre-procarboxypeptidase R, complete cds207442063J04171t,yAlanine and aspartateGlutamic-oxaloaceticGlutamic-oxaloacetic transaminase 1,metabolism, Arginine andtransaminase 1, solublesoluble (aspartate aminotransferase,proline metabolism,(aspartate aminotransferase,cytosolic) see also D1Mgh12Carbon fixation, Cysteinecytosolic) see also D1Mgh12metabolism, Glutamatemetabolism, Phenylalaninemetabolism, Phenylalanine,tyrosine and trytophanbiosynthesis, Tyrosinemetabolism156011372AI169631kProhibitinProhibitin248602135M13506f,l,w,x,ccRat liver UDP-glucuronosyltransferase,phenobarbital-inducible form mRNA, complete cds10555410AA900198General,yESTs, Highly similar to POLIOVIRUSRECEPTOR HOMOLOG PRECURSOR [ M.musculus ]1121573AA817921yESTs, Moderately similar to T25763hypothetical protein F46F11.4 -Caenorhabditis elegans [ C.elegans ]3847315AA892036vESTs, Highly similar to histone deacetylase mHDA2 [ M.musculus ]38231770AI233147rESTs, Weakly similar to nuclear RNA helicase [ R.norvegicus ]150982176M31837p,General,wInsulin-like growthInsulin-like growth factor-binding proteinfactor-binding protein(IGF-PB3)(IGF-BP3)175061134AI070068gESTs, Weakly similar to 2104282A Gadd45 gene [ R.norvegicus ]73441007AI028942GeneralESTs2133386AA894193GeneralESTs186271744AI232284hRT1 class Ib geneRT1 class Ib gene11203339AA892554vESTs, Highly similar to ras-GTPase-activating protein SH3-domain binding protein [ M.musculus ]25198821AF069782GeneralNopp140 associatedNopp140 associated proteinprotein281968D31662d,eRegucalcinRegucalcin6614142AA848389d,General,u,wESTs, Weakly similar to T26686hypothetical protein Y38F1A.6 - Caenorhabditis elegans [ C.elegans ]22804932AI011194ddESTs, Moderately similar to mBLVR [ M.musculus ]20961796AI233801ddESTs166841953D17445General,vTyrosine 3-monooxy-Tyrosine 3-monooxygenase/tryptophan 5-genase/tryptophan 5-monooxygenase activation protein, eta polypeptidemonooxygenase activationprotein, eta polypeptide15882254S61865GeneralSyndecan 1Syndecan 1143462174M31109tRat UDP-glucuronosyltransferase mRNA, complete cds20864812AF045464f,l,General,ccaflatoxin B1 aldehydeaflatoxin B1 aldehyde reductasereductase159061780AI233425ddESTs17427328AA892314hCitrate cycle (TCA cycle),Isocitrate dehydrogenaseIsocitrate dehydrogenase 1, solubleGlutathione metabolism,1, solubleReductive carboxylatecycle CO2 fixation)19275886AI009460iESTs, Highly similar to filamin [ H.sapiens ]129651302AI112926GeneralESTs4879434AA923852e,General,yESTs136941693AI230538jESTs, Weakly similar to PHP DROMEPOLYHOMEOTIC-PROXIMAL CHROMATIN PROTEIN [ D.melanogaster ]35101507AI176423lESTs, Highly similar to ZO1 MOUSETIGHT JUNCTION PROTEIN ZO-1 [ M.musculus ]83031110AI059352GeneralESTs22042598AA946476w,ddESTs13768136AA819792vESTs, Highly similar to R33683 3 [ H.sapiens ]98661911AJ005424c,vRattus norvegicus mRNA for BMK1/ERK5 protein, partial18637217AA858651zRT1 class Ib geneRT1 class Ib gene220771544AI177099zESTs, Highly similar to serine protease [ H.sapiens ]115591029AI030472GeneralESTs98412385U94856p,t,xparaoxonase 1paraoxonase 121524954AI012014vESTs, Highly similar to hypothetical protein [ H.sapiens ]253172035J00735b3417963AI012337GeneralESTs, Highly similar to NHPX RATNHP2/RS6 FAMILY PROTEIN YEL026W HOMOLOG [ R.norvegicus ]16397172AA850155GeneralESTs, Moderately similar to KIAA0264 [ H.sapiens ]146771818AI234620aaEST194072395X02610tGlycolysis/Enolase 1, alphaEnolase 1, alphaGluconeogenesis, Phenyl-alanine, tyrosine andtryptophan biosynthesis6382880AI009362GeneralESTs76651033AI030668o,General,bbRattus norvegicus nucleosome assembly protein mRNA, complete cds94331191AI072917GeneralESTs208032298U09256l,m,ccCarbon fixation, Pentosetransketolasetransketolasephosphate cycle97121527AI176836vESTs, Weakly similar to T21364hypothetical protein F25H5.6 - Caenorhabditis elegans [ C.elegans ]3532119L32591vDNA-damage-inducibleDNA-damage-inducible transcript 1transcript 119031553AI177377cESTs2480375AA893471ccESTs257542505X89696h91281427AI171611g,GeneralESTs151062454X57529h,tESTs, Highly similar to RS18_HUMAN40S RIBOSOMAL PROTEIN S18 [ R.norvegicus ]203501758AI232552GeneralEST3848327AA892306zESTs, Weakly similar to AF114170 1nucleotide-binding protein long form [ M.musculus ]24225482AA925490j,GeneralESTs100551089AI058291tEST, Weakly similar to T19326hypothetical protein C16C10.5 - Caenorthabditis elegans [ C.elegans ]67151642AI228284GeneralESTs155001661AI229337i,lESTs14021153AA848834General,bbESTs207132196M57718k,oFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily IVB, poylpeptide 1Tryptophan metabolismfamily IVB, polypeptide 1229291162AI071578c,d,mESTs, Moderately similar to NEURONAL PROTEIN 3.1 [ M.musculus ]17514486AA925554j,GeneralOxidative phosphorylationHHs:succinate dehy-ESTs, Highly similar to DHSA_HUMANdrogenase complex,SUCCINATE DEHYDROGENASEsubunit A, flavoprotein[ H.sapiens ](Fp)117911569AI177843pESTs, Highly similar to SAS_HUMANsarcoma amplified sequenc [ H.sapiens ]19456729AA997841iRattus norvegicus osteoactivin mRNA, complete cds4374380AA893869mESTs, Weakly similar to T16084hypothetical protein F16H11.1 - Caenorhabditis elegans [ C.elegans ]1654646AA800120k,oR.norvegicus mRNA for camitine/acylcarnitine carrier protein177641816AI234604oHeat shock cognateHeat shock cognate protein 70protein 70141021739AI232131GeneralESTs, Highly similar to beta-hexosaminidase alpha-subunit [ M.musculus ]40911367AI169417General,ccGlycolsis/GluconeogenesisHHs:phosphoglycerateR.norvegicus phosphoglycerate mutase Bmutase 1 (brain)isozyme (PGAM) mRNA, complete cds115631219AI102560qESTs93831120AI059824qESTs22235444AA924152ddESTs, Moderately similar to AF135422 1GDP-mannose pyrophosphorylase A [ H.sapiens ]179081006AI014163t,vinterferon-relatedinterferon-related developmental regulator 1developmental regulator 121204839AF095927aprotein phosphatase 2Cprotein phosphatase 2C237091293AI112173a,tATPase Na+/K+ATPase Na+/K+ transporting beta 1 polypeptidetransporting beta 1polypeptide210392051J03190f,xGlycine, serine andaminolevulinic acidaminolevulinic acid synthase 1threonine metabolismsynthase 126292518Y00396r,GeneralAvian myelocytomatosisAvian myelocytomatosis viral (v-myc)viral (v-myc) oncogeneoncogene homologhomolog75481045AI043724GeneralESTs237811898AI639012iESTs, Moderately similar to unnamed protein product [ H.sapiens ]257192466X62146w603286AA818258GeneralESTs174491884AI237258yMYB binding proteinMYB binding protein (P160) 1a(P160) 1a103481133AI069934ddEST234491526AI176828g,qESTs34302282S85184tCathepsin LCathepsin L16982042J02679p,q,GeneralSterol biosynthesisDiaphorase (NADH/NADPH)Diaphorase (NADH/NADPH)125241958D21800GeneralProteasomeproteasome (prosome,proteasome (prosome, macropain) subunit, beta type 3macropain) subunit, betatype, 3149332020H31588GeneralESTs, Moderately similar to KIAA0351 [ H.sapiens ]22727496AA925814pOxidative phosphoryl-ATP synthase subunit dATP synthase subunit dation, Type III proteinsecretion system207892413X12355gER-60 protease, glucoseER-60 protease, glucose regulated protein,regulated protein,58 kDa58 kDa203841951D17349x,cc,dd65081002AI013900GeneralESTs, Highly similar to PTD001 [ H.sapiens ]25781980D50694GeneralRattus norvegicus mRNA for proteasomal ATPase (MSS1), complete cds6943923AI010637bbESTs90321619AI179950c,d,GeneralESTs, Highly similar to PRC6 RATPROTEASOME SUBUNIT RC6-1 [ R.norvegicus ]200551705AI230762qESTs, Weakly similar to CLP3 RATCALPONIN, ACIDIC ISOFORM [ R.norvegicus ]22820140AA848315GeneralPurine metabolismHMm:inosine 5′-ESTs, Weakly similar to guanosinephosphate dehydrogenase 2monophosphate reductase [ R.norvegicus ]47911600AI179106qESTs22927253AA859920c,hESTs9053358AA892861ddESTs127361807AI233972uGap junction membraneGap junction membrane channel, proteinchannel, protein alphaalpha 4 (connexin 37)4 (connexin 37)57332219M81855iP-glycoprotein/multidrugP-glycoprotein/multidrug resistance 1resistance 1128451387AI170497bESTs18588399AA899635p,x,cc,ddESTs, Moderately similar to 2020285A BRG1 protein [ M.musculus ]171551449AI172090d,GeneralRat clathrin light chain (LCB2) mRNA,complete cds, Rat clathrin light chain (LCB3) mRNA, complete cds66401204AI101500nESTs52001584AI178699jESTs16006AA686470j,wDNA-damage inducibleDNA-damage inducible transcript 3transcript 321510201AA851620GeneralESTs145501263AI104146GeneralESTs, Moderately similar to AC008015 2 unknown [ H.sapiens ]20708767AB006461jneurochondrinRattue norvegicus mRNA for NORBIN, complete cds135511563AI177602mESTs6352721AA997600b,n,yPCTAIRE-1 protein kinase,PCTAIRE-1 protein kinase, alternatively splicedalternatively spliced82831107AI059290d,f,GeneralESTs3690750AA999006i,qESTs255082261S67620n,v263201823AI234927u182502435X51706wribosomal protein L9ESTs, Highly similar to RL9 RAT 60S RIBOSOMAL PROTEIN L9 [ R.norvegicus ]16458549AA944956aESTs11483796AF020618GeneralESTs, Moderately similar to MY16MOUSE MYELOID DIFFERENTIATIONPRIMARY RESPONSE PROTEINMYD116 [ M.musculus ], Rattus norvegicusprogression elevated gene 3 proteinmRNA, complete cds49501910AJ005046bbEST, Highly similar to fructose-1.6-bisphosphatase [ R.norvegicus ]182999AA799369hESTs, Weakly similar to RS9 RAT 40S RIBOSOMAL PROTEIN S9 [ R.norvegicus ]148812155M20629bbEsterase 2Esterase 22165649AA800202zESTs2736388AA894330iCa++/calmodulin-Ca++/calmodulin-dependent proteindependent protein kinasekinase II, delta subunitII, delta subunit208881343AI145680bbSolute carrier 16 (mono-Solute carrier 16 (monocarboxylic acidcarboxylic acid trans-transporter), member 1porter), member 121708641AA956930v,yRat mRNA for endothelin-converting enzyme, complete cds6352490X78848h,w,ccGluthione metabolismGlutathione-S-transfer-Glutathione-S-transferase, alpha type (Ya)ase, alpha type (Ya)260302185M34331cc21040948AI011734f,gGlycine, serine andaminolevulinic acidaminolevulinic acid synthase 1threonine metabolismsynthase 120236835AF091570aolfactory receptor 41olfactory receptor 41145941856AI236152GeneralESTs82111730AI231807nferritin light chain 1ferritin light chain 16171129AA819633bESTs204032AA799700tSelenoamino acidHMm:selenophosphateESTs, Highly similar to SPS2 MOUSEmetabolismsynthetase 2SELENIDE, WATER DIKINASE 2 [ M.musculus ]15577450AA924557oESTs, Highly similar to hepatitis deltaantigen interacting protein A [ H.sapiens ]4196395AA899304o,bbESTs210741001AI013890wESTs8130869AI008894qESTs, Highly similar to T00358 hypothetical protein KIAA0684 [ H.sapiens ]3674566AA945587jESTs26109707AA997009k,o,zEST59211580AI178556aaESTs4636396AA899491uAminoacyl-tRNAHMm:tryptophanyl-tRNAESTs, Highly similar to SYW MOUSEbiosynthesis, TryptophansynthetaseTRYPTOPHANYL-TRNA SYNTHETASE [ M.musculus ]metabolism1552331U32681vcrp-ductincrp-ductin11727163AA849518eESTs95951310AI136630GeneralESTs209252297U08976k,oenoyl hydratase-likeenoyl hydratase-like protein, peroxisomalprotein, peroxisomal25151954D17512bcysteine-rich protein 2cysteine-rich protein 2176262271S78556kESTs, Highly similar to I56581 dnaK-typemolecular chaperone grp75 precursor - rat [ R.norvegicus ]22548550AA945031GeneralESTs206522101L14463vTransducin-like enhancerTransducin-like enhancer of split 4,of split 4, homolog ofhomolog of Drosophila E(spl)Drosophila E(spl)152961652AI228738qFK506-binding protein 1FK506-binding protein 1 (12kD)(12kD)208461715AI231140zESTs, Highly similar to RL2B_HUMAN60S RIBOSOMAL PROTEIN L23A [ R.norvegicus ]222041409AI170820tESTs3693938AI011448pESTs, Highly similar to A49128 cell-fatedetermining gene Notch2 protein - rat [ R.norvegicus ]178871461AI172414GeneralRattus norvegicus apoptosis-regulating basic protein mRNA, complete cds132941789AI233731d,r,GeneralESTs, Weakly similar to TCPA RAT T-COMPLEX PROTEIN 1, ALPHA SUBUNIT [ R.norvegicus ]18319492AA925752bbCD36 antigen (collagenCD36 antigen (collagen type I receptor,type I receptor, thrombo-thrombospondin receptor)spondin receptor)208971487AI175812ddESTs, Highly similar to Copa protein [ M.musculus ]152591575AI178135r,Generalcomplement component 1,complement component 1, qq subcomponent bindingsubcomponent binding proteinprotein220392307U13176jRattus norvegicus clone ubc2e ubiquitinconjugating enzyme (E217kB) mRNA, complete cds168591872AI236753mESTs59371430AI171684aaESTs80251090AI058365iESTs5989640AA956907tESTs, Highly similar to p162 protein [ M.musculus ]43602023H31813e,zESTs, Moderately similar to T14781hypothetical protein DKFZp586B 1621.1 [ H.sapiens ]247631510AI176488Generalnuclear factor I/Bnuclear factor I/B108862250S49003c,dGrowth hormone receptorGrowth hormone receptor21601528AA943997g,GeneralESTs, Moderately similar to p27 [ H.sapiens ]159322306U12402nADP-ribosylation factor-ADP-ribosylation factor-like 1like 123665208AA852055hBruton agammaglobulinemiaBruton agammaglobulinemia tyrosine kinasetyrosine kinase167802468X62660General,zGlutathione metabolismHMm:glutathione S-trans-ESTs, Highly similar to XURT8Cferase, alpha 4glutathione transferase (EC 2.5.1.18)8,cytosolic - rat [ R.norvegicus ]235242067J04792GeneralArginine and prolineOrnitine decarboxylaseOrnitine decarboxylasemetabolism, Urea cycleand metabolism of aminogroups158791644AI228313f,g,h,General,xESTs100201083AI045632GeneralESTs15041780AB016532zperiod homolog 2period homolog 2 ( Drosophila )( Drosophila )202991944D14564cAscorbate and aldarateL-gulono-gamma-L-gulono-gamma-lactone oxidasemetabolismlactone oxidase182270AA817843p,vCCAAT binding tran-CCAAT binding transcription factor of CBF B/NFY-Bscription factor ofCBF-B/NFY-B21588392AA899160ddESTs134581475AI175338aaESTs131661585AI178736vESTs2167931AA799691GeneralESTs, Moderately similar to T31432 K-CIcotransport protein 2, furosemide-sensitive - rat [ R.norvegicus ]174311144AI070521rRat unr mRNA for unr protein with unknown function93391201AI101160GeneralESTs, Weakly similar to S46930 teg292 protein - mouse [ M.musculus ]28551870AI236707iCystatin betaCystatin beta154691912AJ006340c26S proteasome, subunit26S proteasome, subunit p112p112105341148AI070832nESTs109091631AI180425kOxidative phosphorylation,HHs:ATP synthase, H+Rattus norvegicus ATP synthase lipid-Type III secretion systemtransporting, mito-binding protein P3 precursor (Atp5g3)chondrial F0 complex,mRNA, complete cds; nuclear gene forsubunit c (subunit 9)mitochondrial productisoform 329011046AI043752eESTs110571160AI071509GeneralESTs14763541AA944481oESTs, Weakly similar to FIBA RATFIBRINOGEN ALPHA/ALPHA-E CHAIN PRECURSOR [ R.norvegicus ]159551745AI232294i,x,ccESTs95831156AI071185c,m,uESTs12704876AI009194yESTs16821751AA999042nESTs37181667AI229643aaESTs22396250AA859806y,aaESTs155802181M33648oRat mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase mRNA, complete cds1351993D87839e4-aminobutyrate amino-4-aminobutyrate aminotransferasetransferase14311059AI044610GeneralHistidine metabolism,Dopa decarboxylaseDopa decarboxylase (aromatic L-aminoPhenylalanine metabolism,(aromatic L-amino acidacid decarboxylase)Tryptophan metabolism,decarboxylase)Tyrosine metabolism1931530AI176856pFatty acid metabolism,Cytochrome P450 1b1Cytochrome P450 1b1Tryptophan metabolism17564666AA963674nmitogen activated proteinmitogen activated protein kinase kinase 2kinase kinase 222592996AI013740GeneralESTs, Highly similar to proteolipid protein2 [ M.musculus ]2519951AI011770aaESTs2242973AI012635g,i,n,General,yflavin-containing mono-flavin-containing monooxygenase 3oxygenase 374511017AI029450GeneralAminoacyl-tRNA bio-HHs:glutamyl-prolyl-tRNAESTs, Moderately similar tosynthesis, Arginine andsynthetaseSYEP_HUMAN MULTIFUNCTIONALproline metabolism,AMINOACYL-TRNA SYNTHETASEGlutamate metabolism,[ H.sapiens ]Porphyrin and chlorophyll257432493X80130c22612573AA945624j,GeneralESTs, Weakly similar to DHQU RATNAD(P)H DEHYDROGENASE [ R.norvegicus ]16319270AA875047lESTs, Highly similar to TCPZ MOUSE T-COMPLEX PROTEIN 1, ZETA SUBUNIT [ M.musculus ]4232977AI012958l,General,yESTs193631500AI76247l,mESTs, Moderately similar to unnamed protein product [ H.sapiens ]22251644AA957037GeneralESTs, Weakly similar to T19468hypothetical protein C25G4.2 -Caenorhabditis elegans [ C.elegans ]12694657AA957906iESTs3458730AA997861rESTs, Highly similar to CB45 MOUSE 45KDA CALCIUM-BINDING PROTEIN PRECURSOR [ M.musculus ]179132022H31707mESTs, Moderately similar to T50621hypothetical protein DKFZp762O076.1 [ H.sapiens ]3589745AA998590bESTs186821113AI059499GeneralESTs, Highly similar to chaperonincontaining TCP-1 theta subunit [ M.musculus ]6151119AA819199GeneralEST205292118L32132General,wlipopolysaccharidelipopolysaccharide binding proteinbinding protein7782379U84410rCaspase 3, apoptosisCaspase 3, apoptosis related cysteinerelated cysteine proteaseprotease (ICE-like cysteine protease)(ICE-like cysteineprotease)167211965D30647k,z,bbAcyl-Coa dehydrogenase,Acyl-Coa dehydrogenase, Very long chainVery long chain22715591AA946120lESTs29971032AI030545General,w,bbESTs22884925AI010755f,xESTs182661812AI234256GeneralESTs, Highly similar to 2208369A signal peptidase:SUBUNIT199911258AI103956Generalmitochondnal aconitasemitochondrial aconitase (nuclear aco2 gene)(nuclear aco2 gene)4998455AA924683bEST23644655AA957808GeneralESTs, Weakly similar to AF121859 1 sorting nexin 9 [ H.sapiens ]2354726AA997763g,p,qESTs, Highly similar to hypothetical protein [ H.sapiens ]780689AA818421aaESTs190111226AI102618bESTs70031026AI030259nESTs, Weakly similar to REG2 DROMERHYTHMICALLY EXPRESSED GENE 2 PROTEIN [ D.melanogaster ]240481390AI170570GeneralESTs, Highly similar to CGI-10 protein [ H.sapiens ]17324815AF056031p,wkynurenine 3-hydroxylasekynurenine 3-hydroxylase19249713AA997342m,GeneralESTs141711573AI178073cESTs, Weakly similar to T26935hypothetical protein Y45F10D.8 -Caenorhabditis elegans [ C.elegans ]19938623AA955980gESTs, Moderately similar to pescadillo [ H.sapiens ]101611104AI059168ddEST15292218M81687e,qRyudocan/syndecan 2Ryudocan/syndecan 225541922D00913vIntercellular adhesionIntercellular adhesion molecule 1molecule 121285169AA849898w,zEST1857772AB010428k,o,bbacyl-CoA thioesterase 1,acyl-CoA thioesterase 1, cytosoliccytosolic96441159AI071410zESTs21917291AA891220bESTs172812304U10697cccarboxylesterase 1carboxylesterase 1238651229AI102760GeneralESTs, Moderately similar to KIAA0710 protein [ H.sapiens ]18132152M19651jFos-like antigen 1Fos-like antigen 14242372AA893325c,d,GeneralArginine and prolineornithine aminotrans-ornithine aminotransferasemetabolism, Ureaferasecycle and metabolism ofamino groups3552260S66024o,Generaltranscriptionalrepressor CREM18580206AA851963wESTs4833875AI009178bESTs, Highly similar to glycogen phosphorylase [ R.norvegicus ]87591887AI237646jESTs30231408AI170795GeneralESTs25183813AF050159linsulin receptorsubstrate 211732150M18363mFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily IICTryptophan metabolismfamily IIC (mephenytoin(mephenytoin 4-hydroxylase)4-hydroxylase)214882330U32575p,vESTs, Highly similar to similar to yeastSec6p, Swiss-Prot Accession Number P32844 [ R.norvegicus ]23886660AA963008zESTs, Highly similar to U123_HUMANHYPOTHETICAL 12.4 KDA PROTEIN BK223H9.2 [ H.sapiens ]8182393X02291nCarbon fixation, FructoseAldolase B, fructose-Aldolase B, fructose-biphosphateand mannose metabolism,biphosphateGlycolysis/Gluconeogenesis,Inositol metabolism,Pentose phosphate cycle2334445AA800034GeneralESTs99312281S83279f,k,oAndrogen and estrogenperoxisomal multi-peroxisomal multifunctional enzyme type IImetabolismfunctional enzyme type II177362229M86389bbHeat shock 27 kDaESTs, Heat shock 27 kDa proteinprotein183522527Z12298udecorindecorin11876879AI009321General,ddESTs, Highly similar to similar to humanDNA-binding protein 5 [ H.sapiens ]22540454AA924630GeneralGlyoxylate and dicar-HHs:glyoxylateESTs, Weakly similar to SERA RAT D-3-boxylate metabolism,reductase/hydroxy-PHOSPHOGLYCERATE DEHYDROGENASE [ R.norvegicus ]Pyruvate metabolismpyruvate reductase23068500AA926036e,GeneralESTs208162199M58404uthymosin beta-10thymosin beta-10100871435AI171803GeneralESTs61661309AI136516GeneralESTs12563683AA964533GeneralESTs, Moderately similar to density-regulated protein [ H.sapiens ]24179368AA893091jESTs, Moderately similar to KRAB-zinc finger protein KZF-2 [ R.norvegicus ]8182570AA945608t,bbserum amyloid P-serum amyloid P-componentcomponent12071885AI009456d,l,GeneralESTs, Moderately similar to KIAA0822 protein [ H.sapiens ]192562144M15562lRat (diabetic BB) MHC class II alpha chain RT1.D alpha (u)12320592AA946149wESTs60851443AI171990vESTs, Moderately similar to axonemal dynein heavy chain [ H.sapiens ]212881637AI227935p,qESTs125231958D21800GeneralProteasomeproteasome (prosome,proteasome (prosome, macropain)macropain) subunit,subunit, beta type, 3beta type, 343952027H33149iESTs, Weakly similar to T29897hypothetical protein F38A5.1 -Caenorhabditis elegans [ C.elegans ]16026264AA874802aaHistone H1-0Histone H1-0168092459X58828m,General,uRat PTP-S mRNA for protein-tyrosine phosphatase14472451X55986GeneralProteasomeproteasome (prosome,proteasome (prosome, macropain)macropain) subunit,subunit, alpha type 4alpha type 454511053AI044322bbESTs, Highly similar to 26S proteasome subunit p55 [ H.sapiens ]65321810AI234105a,m,uESTs7171974AI012761GeneralESTs30191718AI231218nESTs230991297AI112365General,aaESTs, Highly similar to mm-Mago [ M.musculus ]189892077K00136f,q,xGlutathione metabolismGlutathione-S-trans-Glutathione-S-transferase, alpha type (Yc?)ferase, alpha type (Yc?)139111859AI236262j,aaRattus norvegicus epidermal Langerhanscell protein LCP1 mRNA, complete cds238551874AI236773vESTs157182371U75689GeneralRattus norvegicus DNAseY mRNA, complete cds12118347AA892775uLysozymeLysozyme12092147AA848618aESTs242192116L27843g,m,n,t,u,vprotein tyrosineprotein tyrosine phosphatase 4a1phosphatase 4a1167061624AI180032GeneralESTs5176748AA998722upyruvate kinase 3Rat mRNA for pituitary pyruvate kinase10018453AA924622GeneralESTs176851305AI113055lEST23080651AA957423GeneralESTs, Moderately similar to Rat NBP60 [ R.norvegicus ]88501828AI235059j,aaESTs5186489AA925674aaESTs152861366AI169361GeneralESTs, Highly similar to U1 snRNP-specific protein C [ M.musculus ]41831231AI102789yESTs, Weakly similar to PTB RATPOLYPYRIMIDINE TRACT-BINDING PROTEIN [ R.norvegicus ]8527700AA996461f,oESTs6438122AA819269n,GeneralESTs162722488X76456f,ccR.norvegicus (Sprague Dawley) alpha albumin gene6108307AA891873d,GeneralATPase inhibitor (ratATPase inhibitor (rat mitochondrial IF1 protein)mitochondnal IF1 protein)116601595AI178944General,aaESTs, Highly similar to AF167573 1protein methyltransferase [ M.musculus ]151852471X62952uvimentinvimentin100191586AI178756GeneralESTs235871517AI176598vESTs6502450X55286cSterol biosynthesis3-hydroxy-3-methylglu-3-hydroxy-3-methylglutaryl-Coenzyme Ataryl-Coenzyme Areductasereductase17942475X64401f,g,h,cc,ddCytochrome P450, sub-Cytochrome P450, subfamily IIIA,family IIIA, polypeptidepolypeptide 3323679830AF087037aaB-cell translocationB-cell translocation gene 3gene 3153651562AI177598Generalcofilin, non-musclecofilin, non-muscle150801210AI102045tESTs, Highly similar to OS-4 protein [ H.sapiens ]210661926D10587c,General,uRat lysosomal membrane protein (LIMPII) mRNA, complete cds105331091AI058430j,GeneralESTs, Highly similar to HG17 RATNONHISTONE CHROMOSOMAL PROTEIN HMG-17 [ R.norvegicus ]21341174AA850195k,o,yESTs15011185AI072634wRattus norvegicus cytokeratin-18 mRNA, partial cds17953385AA894090vESTs197321850AI236066ddESTs22846436AA923982GeneralESTs, Highly similar to ATP-specificsuccinyl-CoA synthetase beta subunit [ M.musculus ]21522540AA944449wESTs, Highly similar to SR68_HUMANSIGNAL RECOGNITION PARTICLE 68KDA PROTEIN (SRP68)[ H.sapiens ]172141897AI639008vESTs83871504AI176365eESTs102291117AI059618GeneralESTs, Highly similar to UDP1_HUMANUTP-GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE 1 [ H.sapiens ]18316822AF072411bbCD36 antigen (collagenCD36 antigen (collagen type I receptor,type I receptor,thrombospondin receptor)thrombospondin receptor)234941410AI170967GeneralRattus norvegicus zygin-related proteintype II (Zrp2) mRNA, partial cds201462159M22926emuscarinic acetylcholinemuscarinic acetylcholine receptor M5receptor M5169222248S45663hESTs, Weakly similar to S5A2 RAT 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2 [ R.norvegicus ]223521491AI175959eESTs179952136M13646xRattus norvegicus Sprague Dawleytestosterone 6-beta-hydroxylase,cytochrome P450/6-beta-A, (CYP3A2) mRNA, complete cds8702361U66478vMAD (mothers againstMAD (mothers against decapentaplegic,decapentaplegic,Drosophila ) homolog 1Drosophila ) homolog 154211202AI101270iESTs, Highly similar to GDIS MOUSERHO GDP-DISSOCIATION INHIBITOR 2[ M.musculus ]146641736AI232081jESTs212281056AI044404lESTs1732424X15580rFroctose and mannose6-Phosphofructo-2-kinase/6-Phosphofructo-2-kinase/fructose-2,6-metabolismfructose-2,6-bisphosphatasebisphosphatase 1 (liver and muscle)1 (liver and muscle)19259421AA900613r,bbESTs14267949AI011738o,ddESTs, Highly similar to P044 RAT 0-44PROTEIN [ R.norvegicus ]183862093L03294iGlycerolipid metabolismLipoprotein lipaseESTs, Highly similar to LIPL RATLIPOPROTEIN LIPASE PRECURSOR[ R.norvegicus ], Lipoprotein lipase26051387AA894316General233901460AI172328GeneralRNA binding proteinRNA binding protein p45AUF1p45AUF1233311781AI233457aaESTs, Weakly similar to HUD RATENCEPHALOMYELITIS ANTIGEN HUD PARANEOPLASTICHOMOLOG [ R.norvegicus ]22953600AA946509fESTs, Highly similar to 26S proteasomesubunit p44.5 [ H.sapiens ]23930711AA997182xESTs, Highly similar to RPB8_HUMANDNA-DIRECTED RNA POLYMERASES I,II, AND III 17.1 KD POLYPEPTIDE [ H.sapiens ]5990640AA956907g,tESTs, Highly similar to p162 protein [ M.musculus ]210621039AI043631yornithine decarboxylaseornithine decarboxylase antizyme inhibitorantizyme inhibitor32921921D00753bSerine protease inhibitorSerine protease inhibitor6662126M10072uRat nRNA for leucocyte-common antigen (L-CA)76841025AI030242aESTs198841388AI170501vESTs, Moderately similar to 0806162Hprotein URF3 [ M.musculus ]1799754AA800671GeneralESTs, Moderately similar to A54854 RasGTPase activating protein-related protein [ H.sapiens ]98211626AI180114vESTs, Highly similar to NIP2I [ M.musculus ]235961282AI105435GeneralFatty acid metabolism,HMm:glutaryl-Coenzyme AESTs, Highly similar to GCDH MOUSELysine degradation,dehydrogenaseGLUTARYL-COA DEHYDROGENASE PRECURSOR [ M.musculus ]Tryptophan metabolism12233990AI013474zESTs, Weakly similar to AF189764 1alpha/beta hydrolase-1 [ M.musculus ]601684AA818163d,m,p,vEST102482109L23148n,rInhibitor of DNA bindingInhibitor of DNA binding 1, helix-loop-helix1, helix-loop-helixprotein (splice variation)protein (splice variation)182932401X05341f,k,oBile acid biosynthesis,HHs:acetyl-Coenzyme ARat mRNA for 3-oxoacyl-CoA thiolaseFatty acid biosynthesisacyltransferase 2(path 2), Fatty acid(mitochondrial 3-oxoacyl-metabollsm, PhenylalanineCoenzyme A thiolase)metabolism, Valine,leucine and icoleucinedegradation6844901AI009770GeneralESTs17368417AA900548GeneralESTs, Weakly similar to T30021hypothetical protein K08F11.4 -Caenorhabditis elegans [ C.elegans ]114191421AI171365GeneralESTs, Weakly similar to DDX4 RAT DEADBOX PROTEIN 4 [ R.norvegicus ]2047663AA963366aESTs, Highly similar to TPMB RABITTROPOMYOSIN BETA CHAIN,SKELETAL MUSCLE [ R.norvegicus ]6712289U04808a,GeneralRattus norvegicus Sprague-Dawleyputative G-protein coupled receptor (GCR) mRNA, complete cds3705752AA999054aaESTs26133905AI009950b,General70671669AI229655GeneralESTs69451663AI229467d,GeneralESTs19624743AA998422mEST18244151AA848776wESTs2102942AA799981xESTs15849853AI008074zESTs, ESTs, Highly similar to HS9B RATHEAT SHOCK PROTEIN HSP 90-BETA [ R.norvegicus ]1836927AA799645GeneralFXYD domain-containingFXYD domain-containing ion transport regulator 1ion transport regulator 122130517AA943020aaESTs15180915AI010354nESTs156212065J04473tCitrate cycle (TCA cycle),Fumarate hydrataseFumarate hydrataseReductive carboxylatecycle (CO2 fixation)172842048J02827wValine, leucine andBranched chain alpha-Branched chain alpha-ketoacidisoleucine degradationdehydrogenase subunitdehydrogenase subunit E1 alpha E1 alpha91621178AI072392aESTs, Highly similar to complement component C2 [ M.musculus ]3944422AA900688rESTs, Highly similar to phosphoprotein [ M.musculus ]24521574AA945636ccESTs, Highly similar to 60S ACIDIC RIBOSOMAL PROTEIN P1 [ R.norvegicus ]5027460AA924793bbESTs152521582AI178605p,q,ddESTs, Highly similar to CSK RATTYROSINE-PROTEIN KINASE CSK [ R.norvegicus ]1699320AA799560d,g,uESTs164111094AI058647bbESTs207831442AI171966uR.norvegicus mRNA for RT1.Mb171542145M15883fRat clathrin light chain (LCB2) mRNA,complete cds, Rat clathrin light chain (LCB3) mRNA, complete cds17588356AA892849vESTs, Weakly similar to MXI1 RAT MAX INTERACTING PROTEIN 122978254AA859931aESTs, Highly similar to R26445 1 [ H.sapiens ]241461373AI169668jESTs, Weakly similar to hypothetical protein [ H.sapiens ]99291000AI013834k,oAndrogen and estrogenperoxisomal multifunc-peroxisomal multifunctional enzyme type IImetabolismtional enzyme type II250902473X63594General3542119L32591oDNA-damage-inducibleDNA-damage-inducible transcript 1transcript 17246988AI013331fESTs15644911AI010256gR.norvegicus mRNA for histone H3.3141991811AI234133iRattus norvegicus gcd-10S mRNA, complete cds73171307AI136123lESTs, Moderately similar to ZNF127-Xp [ H.sapiens ]91911170AI072107c,uESTs, Weakly similar to PE2R RAT 20-ALPHA-HYDROXYSTEROIDDEHYDROGENASE [ R.norvegicus ]158501876AI236795f,oESTs, ESTs, Highly similar to HS9B RATHEAT SHOCK PROTEIN HSP 90-BETA [ R.norvegicus ]173942062J03969General,tNucleoplasmin-relatedNucleoplasmin-related protein (Nuclearprotein (Nuclearprotein B23protein B23140041776AI233261jGlutamate metabolism,Glutamate-cysteineGlutamate-cysteine ligase (gamma-Glutathione metabolismligase (gamma-glutamyl-glutamylcysteine synthetase), regulatorycysteine synthetase),regulatory9150877AI009198g,GeneralESTs, Highly similar to serine-threoninekinase receptor-associated protein [ M.musculus ]137851655AI228970GeneralESTs230781668AI229647GeneralESTs17339162AA849497jESTs177871376AI169758nApolipoprotein C-IIIApolipoprotein C-III32791241AI103224zESTs, Weakly similar to putative short-chain dehydrogenase/reductase [ R.norvegicus ]145820AF064541harginine vasopressinarginine vasopressin receptor 1Breceptor 1B228761445AI172041GeneralESTs, Moderately similar to CGI-137 protein [ H.sapiens ]29111036AI030835eESTs150692232M89945eSterol biosynthesis,testis-specific famesyltestis-specific famesyl pyrophosphate synthetaseTerpenoid biosynthesispyrophosphate synthetase134341466AI172552GeneralEST23305652AA957451bbRattus norvegicus mRNA for NAD+-specific isocitrate dehydrogenase a-subunit, complete cds12462195M57507cPurine metabolismGuanylate cyclase,Guanylate cyclase, soluble, beta 2 (GTPsoluble, beta 2 (GTPpyrophosphate - lyase)pyrophosphate - lyase)65371798AI233817vkidney-derived aspartickidney-derived aspartic protease-like proteinprotease-like protein197281385AI170394GeneralESTs92671177AI072384General,uRattus norvegicus formiminotransferase-cyclodeaminase mRNA, complete cds95241196AI073249aaESTs, Highly similar to U4/U6-associatedRNA splicing factor [ H.sapiens ]3880371AA893247rESTs, Highly similar to serine/threoninekinase [ R.norvegicus ]245982167M25758iphosphatidylinositolphosphatidylinositol transfer proteintransfer protein14792329U32314lAlanine and aspartatePyruvate carboxylasePyruvate carboxylasemetabolism, Citratecycle (TCA cycle),Pyruvate metabolism204492431X17053mSmall inducible gene JESmall inducible gene JE23055515AA942929GeneralESTs15018685AA964688GeneralESTs12306547AA944898i,pESTs96741588AI178784GeneralESTs7069912AI010301eESTs17167994AI013690iESTs216251597AI179012tcytoplasmic beta-actincytoplasmic beta-actin238692369U75397GeneralEarly growth response 1Early growth response 116320252AA859899f,GeneralEST219772249S46785mRattus norvegicus onsulin-like growthfactor binding complex acid-labile subunit gene, complete cds13012037J02585zRat liver stearyl-CoA desaturase mRNA, complete cds153742033H34186d,GeneralESTs, Highly similar to IF39_HUMANEUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 920051964D29646u,vNicotinate andCD38 antigen (ADP-riosylCD38 antigen (ADP-ribosyl cyclase/nicotinamide metabolismcyclase/cyclic ADP-cyclic ADP-ribose hydrolase)ribose hydrolase)26191720AI231290GeneralESTs, Moderately similar toARDH_HUMAN N-TERMINALACETYLTRANSFERASE COMPLEX ARD1 SUBUNIT HOMOLOG [ H.sapiens ]133171252AI103637GeneralESTs, Weakly similar to D52 [ M.musculus ]83441115AI059511c,eEST31141493AI176018ddESTs, Highly similar to apyrase [ H.sapiens ]78041794AI233771r,tESTs18927152AA848813GeneralESTs, Highly similar to DP1 MOUSEPOLYPOSIS LOCUS PROTEIN 1 HOMOLOG [ M.musculus ]59161448AI172078aaESTs12119159AA849354tESTs, Moderately similar to KIAA0948 protein [ H.sapiens ]80361708AI230884lESTs2373682AA964455General,zESTs6017806AF037072cNitrogen metabolismcarbonic anhydrase 3carbonic anhydrase 34942529Z24721GeneralSuperoxide dimutase 3Superoxide dimutase 311520708AA997068bbESTs, Weakly similar to CAG6 RAT CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE [ R.norvegicus ]17482225M84488uVascular cell adhesionVascular cell adhesion molecule 1molecule 1245822430X16554cPentose phosphate cycle,phosohoribosly pyrophos-phosphoribosyl pyrophosphate synthetase 1Purine metabolismphate synthetase 115623168AA849769ffollistatin-relatedfollistatin-related protein precursorprotein precursor55971207AI101622eESTs6342082K01932h,t,w,x,ccGlutathione metabolismGlutathione-S-trans-Glutathione-S-transferase, alpha type (Ya)ferase, alpha type (Ya)10176128AA819530yE-septinE-septin6322109AA818801uESTs194631256AI103915aaESTs, Weakly similar to T25460hypothetical protein B0432.3 -Caenorhabditis elegans [ C.elegans ]157861005AI013924n,yESTs15606537AA944401GeneralESTs, Moderately similar to B Chain B,Vhs Domain Of Tom1 Protein From H.Sapien [ H.sapiens ]26045379AA893803GeneralESTs17334219AA858704aaESTs, Weakly similar to Reg receptor [ R.norvegicus ]22069594AA946349vESTs173772416X13058vTumor protein p53 (Li-Tumor protein p53 (Li-Fraumeni syndrome)Fraumeni syndrome)593465AA817695e,mESTs, Highly similar to 2008147C proteinRAKd [ R.norvegicus ]252871972D38069i14302226M84648e,GeneralHistidine metabolism,Dopa decarboxylaseDopa decarboxylase (aromatic L-aminoPhenylalanine metabolism,(aromatic L-aminoacid decarboxylase)Tryptophan metabolism,acid decarboxylase)Tyrosine metabolism156631484AI175566Generalt-complex testist-complex testis expressed 1expressed 1137571650AI228676nESTs, Weakly similar to T15736hypothetical protein C32D5.6 -Caenorhabditis elegans [ C.elegans ]209831065AI044900d,rFatty acid metabolismAcyl CoA synthetase,Acyl CoA synthetase, long chainlong chain4674404AA899847GeneralESTs, Weakly similar to S26689hypothetical protein hc1 - mouse [ M.musculus ]90291967D30804GeneralESTs, Highly similar to PRC6 RATPROTEASOME SUBUNIT RC6-1 [ R.norvegicus ]165611325AI137862b,Generalp38 mitogen activatedP38 mitogen activated protein kinaseprotein kinase229171640AI228120lRattus norvegicus GCIP-interactingprotein p29 mRNA, complete cds145062025H32584zESTs110661163AI071602aESTs16327271AA875050nESTs178791702AI230741GeneralESTs47031728AI231606GeneralESTs, Weakly similar to YII3_YEASTHYPOTHETICAL 41.9 KD PROTEIN INSDS3-THS1 INTERGENIC REGION[ S.cerevisiae ]217991222AI102576yESTs11067966AI012397GeneralESTs94101188AI072842aaESTs115421396AI170664aaESTs20842166AA849722fProteasomeHMm:proteasome (prosome,Rat mRNA for proteasome subunit RC5macropain) subunit, betatype 1101521102AI059110f,x,ddEST28221793AI233763GeneralESTs17721578AA945762j,GeneralESTs, Weakly similar to PTNL RATPROTEIN TYROSINE PHOSPHATASE,NON-RECEPTOR TYPE 21[ R.norvegicus ]15703770AB009372b,p,GeneralRattus norvegicus mRNA for Lysophospholipase, complete cds255812308U13396iepo, ifn_gamma,Janus kinase 2 (aJanus kinase 2 (a protein tyrosine kinase)il3, il6, interact6-1,protein tyrosine kinase)5193491AA925693aaEST85922029H33491GeneralRattus norvegicus sterol delta 8-isomerase (RSI) mRNA, complete cds151242039J02612f,g,h,k,q,x,ccAndrogen and estrogenUDP-glucuronosyltrans-Rattus norvegicus UDP-metabolism, Pentose andferase 1 family,glucuronosyltransferase UGT1A7 mRNA,glucuronate inter-member 1complete cds, UDP-conversions, Porphyrin andglucuronosyltransferase 1 family, memberchlorophyll metabolism,1Starch and sucrosemetabolism246932042J02720hArginine and prolinearginase 1, liverarginase 1, livermetabolism, Urea, cycleand metabolism of aminogroups50821943D14015r,GeneralCyclin eESTs, Highly similar to CGE1 RAT G1/S-SPECIFIC CYCLIN E1 [ R.norvegicus ]229661687AI230320aaESTs4462258AA866264GeneralESTs, Weakly similar to PE2R RAT 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE [ R.norvegicus ]20853819AF063302bbFatty acid metabolism,Carnitine palmitoyl-Carnitine palmitoyltransferase 1 beta,Glycerolipid metabolismtransferase 1 beta,muscle isoformmuscle isoform208682177M32062uRat Fc-gamma receptor mRNA, complete cds926759AB003042iR.norvegicus mRNA for C5a receptor59691218AI102520wESTs, Moderately similar to AF161588 1GABA-A receptor-associated protein [ R.norvegicus ]17956681AA964379rR.norvegicus beta-chain clathrinassociated protein complex AP-2 mRNA, complete cds208192217M81225vFamesyltransferase,Famesyltransferase, subunit alphasubunit alpha150881761AI232613GeneralESTs, Highly similar to AF151886 1 CGI-128 protein [ H.sapiens ]5936674AA964214cESTs18542083K02814a,bK-kininogen, differen-K-kininogen, differential splicing leads totial splicing leads toHMW Kngk, T-kininogenHMW Kngk, T-kininogen256912443X53504cc131671346AI145832General,aaESTs, Moderately similar toYCD1_HUMAN HYPOTHETICALPROTEIN CGI-131 [ H.sapiens ]70632133M12919v,yCarbon fixation, FructoseAldolase A, fructose-Aldolase A, fructose-bisphosphateand mannose metabolism,bisphosphateGlycolysis/Gluconeogenesis,Inositol metabolism,Pentose phosphate cycle41992220M83143b,e,bbRat beta-galactoside-alpha 2,6-sialyltransferase mRNA117081436AI171807gESTs19231402AI170754jESTs, Highly similar to AF151885 1 CGI-127 protein [ H.sapiens ]21895872AI008971bbESTs210142060J03914xGlutathione metabolismGlutathione-S-trans-Glutathione-S-transferase, mu type 2 (Yb2)ferase, mu type 2 (Yb2)2713659AA962943qESTs, Moderately similar to Notch4 [ M.musculus ]91801044AI043694bbESTs, Weakly similar to T27134hypothetical protein Y53C12B.2 -Caenorhabditis elegans [ C.elegans ]171042171M29358General,ccribosomal protein S6ribosomal protein S63365870AI008919vESTs596272AA817875mESTs3082754AA999172GeneralGlutamate metabolism,HHs:guanine monphosphateESTs, Highly similar to GUAA_HUMANPurine metabolismsynthetaseGMP SYNTHASE [ H.sapiens ]101101098AI058863jEST235361483AI175558GeneralESTs23285622AA955976bbESTs12829218AA858695z,bbESTs, Highly similar to ganglioside-induced differentiation associated protein 3 [ M.musculus ]5342197M58041hRat p450Md mRNA for cytochrome P-450252791966D30740i14 - 3 - 3 - zeta isoform,Tyrosine 3-monooxygenase/tryptophan 5-Tyrosine 3-monooxygenase/monooxygenase activation protein, zetatryptophan 5-monooxygenasepolypeptideactivation protein, zetapolypeptide166181352AI168967j,aaESTs, Moderately similar to methyl-CpGbinding protein MBD1 [ M.musculus ]179582184M34176hR.norvegicus beta-chain clathrinassociated protein complex AP-2 mRNA, complete cds15787837AF095576iRattus norvegicus APS protein mRNA, complete cds176012513X95577k5′-AMP-activated5′-AMP-activated protein kinase, betaprotein kinase, betasubunitsubunit136462467X62166GeneralESTs, Highly similar to RL3 RAT 60SRIBOSOMAL PROTEIN L3 [ R.norvegicus ]77842066J04591zDipeptidyl peptidase 4Dipeptidyl peptidase 438601764AI232703bbmalonyl-CoA decarboxylasemalonyl-CoA decarboxylase14782329U32314d,lAlanine and aspartatePyruvate carboxylasePyruvate carboxylasemetabolism, Citratecycle (TCA cycle),Pyruvate metabolism365585AA818183General,aaESTs, Highly similar to RPA5 MOUSEDNA-DIRECTED RNA POLYMERASE I 40 KDA POLYPEPTIDE [ M.musculus ]19443354AA892832p,qESTs92881180AI072458aaESTs190182230M86870wRat calcium-binding protein mRNA, complete cds189781902AI639208eESTs, Highly similar to AF186115 1putative secreted protein ZSIG9 ] M.musculus ]9633842AI007768eRattus norvegicus CPI17 (Cpi17) mRNA, complete cds180951558AI177482dSH-PTP2 protein tyrosineSH-PTP2 protein tyrosine phosphatase,phosphatase, non-receptornon-receptor type 11type 112104237AA799814tESTs, Weakly similar to KCCD RATCALCIUM/CALMODULIN-DEPENDENTPROTEIN KINASE TYPE II DELTACHAIN [ R.norvegicus ]162781974D38381ddR.norvegicus CYP3 mRNA205132402X05684eCarbon fixation,Pyruvate kinase, liverPyruvate kinase, liver and RBCGlycolysis/Gluconeogenesis,and RBCPurine metabolism,Pyruvate metabolism179992313U19485f,bbRattus norvegicus spp-24 precursor mRNA, partial cds2899702AA996698yEST162172373U75928dSecreted acidic cystein-Secreted acidic cystein-rich glycoproteinrich glycoprotein(osteonectin)(osteonectin)204292069J05035pAndrogen and estrogenSteroid-5-alpha-reductase,Steroid-5-alpha-reductase, alphametabolism, Bile acidalpha polypeptide 1 (3-oxo-polypeptide 1 (3-oxo-5 alpha-steroid deltabiosynthesis5 alpha-steroid delta 44-dehydrogenase alpha 1)dehydrogenase alpha 1)1792788AF004218fopioid receptor, sigma 1opioid receptor, sigma 191341977D45247fProteasomeproteasome beta typesubunit 57031936AI011291bbESTs171071581AI178582General,zribosomal protein S6ribosomal protein S6122991444AI172017hArginine and prolinealdehyde dehydrogenasealdehyde dehydrogenase 2, mitochondrialmetabolism, Ascorbate2, mitochondrialand aldarate metabolism,Bile acid biosynthesis,Butanoate metabolism,Fatty acid metabolism,Glycerolipid metabolism,Histidine metabolism,Lysine degradation,Propanoate metabolism,Pyruvate metabolism,Tryptophan metabolism,Valine, leucine andisoleucine degradation,beta-Alanine metabolism254062149M18330dd23448471AA925167g,q,GeneralESTs5999116GeneralESTs246491825AI234950p,qRiboflavin metabolismAcid phosphatase 2,Acid phosphatase 2, lysozymallysozymal115761350AI146177nESTs255742295U06752hprotein phosphatase 1,protein phosphatase 1, regulatoryregulatory (inhibitor)(inhibitor) subunit 5subunit 5153791901AI639162pESTs65982201M58587nil6, interact6-1Interleukin 6 receptorInterleukin 6 receptor3731991D86086General,x,y,bbCanalicular multispecificCanalicular multispecific organic anion transporterorganic anion transporter248252396X02741a,tPhenylalanine metabolism,Tyrosine aminotransferaseTyrosine aminotransferasePhenylalanine, tyrosineand tryptophan biosynthesis,Tyrosine metabolism257252468X62660General,x,z191851284AI111361qESTs256792421X15013a,w,cc4899439AA924017nEST21923293AA891260yESTs236982044J02749k,o,z,ccBile acid biosynthesis,Acetyl-CoA acyltrans-Acetyl-CoA acyltransferase, 3-oxo acyl-Fatty acid biosynthesisferase, 3-oxo acyl-CoACoA thiolase A, peroxisomal(path 2), Fatty acidthiolase A, peroxisomalmetabolism, Phenylalaninemetabolism, Valine,leucine and isoleucinedegradation57911081AI045423mESTs50741209AI101695l,aaESTs257182465X62145Generalribosomal protein L8217462092L02896ccglypican 1glypican 1129461643AI228291eESTs63871819AI234664e,mESTs87951469AI172618jESTs Caenorhabditis elegans [ C.elegans ]208802123L46791Generalcarboxylesterase 1carboxylesterase 1136451763AI232694cESTs, Weakly similar to Y079_HUMANHYPOTHETICAL PROTEIN KIAA0079 [ H.sapiens ]2468690AA964807g,GeneralESTs, Weakly similar to T23337hypothetical protein K05C4.2 -Caenorhabditis elegans [ C.elegans ]1542331U32681wcrp-ductincrp-ductin11726163AA849518eESTs23584604AA955071p,qretinoid X receptorretinoid X receptor gamma (gamma (245772449X55153c,wESTs, Highly similar to 60S ACIDICRIBOSOMAL PROTEIN P2 [ R.norvegicus ]64721490AI175880General,ddESTs142541262AI103988GeneralESTs, Highly similar to I67805 purinesynthesis multifunctional protein - mouse [ M.musculus ]150031365AI169327m,uRattus norvegicus tissue inhibitor ofmetalloproteinase-1 (TIMP1), mRNA, complete cds254802249S46785c,m181752054J03621kRat mitochondrial succinyl-CoAsynthetase alpha subunit (cytoplasmic precursor) mRNA, complete cds201622432X17163megf, epo, igf-1, iI2, iI6,Avian sarcoma virus 17Avian sarcoma virus 17 (v-jun) oncogene homologinsulin, ngf, pdgf, tpo(v-jun) oncogene homolog207352503X89225d,gantigen identified byantigen identified by monoclonal antibodies 4F2monoclonal antibodies 4F264791374AI169690l,GeneralFibrinogen, gammaFibrinogen, gamma polypeptidepolypeptide236062293U05784q,General,ymicrotubule-associatedmicrotubule-associated proteins 1A/1Bproteins 1A/1B lightlight chain 3chain 3236081773AI233190n,q,Generalmicrotubule-associatedmicrotubule-associated proteins 1A/1Bproteins 1A/1B lightlight chain 3chain 3117201743AI232273m,GeneralESTs, Highly similar to RNA cyclase homolog [ H.sapiens ]151272252S56937f,g,l,q,General,xAndrogen and estrogenUDP-glucuronosyltrans-Rattus norvegicus UDP-metabolism, Pentose andferase 1 family,glucuronosyltransferase UGT1A7 mRNA,glucuronate interconver-member 1complete cds, UDP-sions, Porphyrin andglucuronosyltransferase 1 family, member 1chlorophyll metabolism,Starch and sucrosemetabolism4205953AI011982GeneralESTs22534465AA925045gESTs15712291U05014GeneralRattus norvegicus Sprague/Dawley PHASI mRNA, complete cds206461886AI237641GeneralESTs, Weakly similar to JC4230ribosomal protein L7 - rat [ R.norvegicus ]21995871AI008955bbESTs6431232AA859085l,mESTs202113L26268yB-cell translocation geneB-cell translocation gene 1, anti-proliferative1, anti-proliferative42261567AI177752iESTs1061791AF009329iRattus norvegicus enhancer-of-split andhairy-related protein 1 (SHARP-1) mRNA, complete cds203852448X54793h,k,xheat shock protein 60heat shock protein 60 (liver)(liver)21818804AF036537GeneralRattus norvegicus homocysteinerespondent protein HCYP2 mRNA, complete cds154081918D00569k,oRattus norvegicus mRNA for 2,4-dienoyl-CoA reductase precursor, complete cds1409975AI012802cPyruvate metabolismHHs:hydroxyacyl gluta-Rattus norvegicus round spermatid proteinthione hydrolaseRSP29 gene, complete cds150562354U60578rNitrogen metabolismcarbonic anhydrase 2carbonic anhydrase 219202125M10068g,GeneralP450 (cytochrome) oxi-P450 (cytochrome) oxidoreductasedoreductase96202440X53377hribosomal protein S7ribosomal protein S7183852093L03294iGlycerolipid metabolismLipoprotein lipaseLipoprotein lipase17492148M17526lGTP-binding proteinGTP-binding protein187192472X63410h,bbAndrogen and estrogenRat senescence markerRat senescence marker protein 2A gene,metabolismprotein 2A gene, exonsexons 1 and 21 and 24052481X70223dperoxisomal membraneperoxisomal membrane protein 2, 22 kDaprotein 2, 22 kDa115251457AI172286bbESTs, Weakly similar to L130_HUMAN130 KD LEUCINE-RICH PROTEIN [ H.sapiens ]211961063AI044873GeneralESTs23766631AA956456ccESTs15558286AA875537General,tESTs, Weakly similar to A46241 interferonresponse element-binding factor IREBF-2 mouse [ M.musculus ]177031757AI232498GeneralESTs229571275AI104897jESTs, Moderately similar to meningioma-expressed antigen 11 [ H.sapiens ]21491809AF040954vputative protein phos-putative protein phosphatase 1 nuclearphatase 1 nucleartargeting subunittargeting subunit19942790AF008554vRattus norvegicus implantation-associatedprotein (IAG2) mRNA, partial cds1912299U09540pFatty acid metabolism,Cytochrome P450 1b1Cytochrome P450 1b1Tryptophan metabolism91571618AI179947qESTs14421511AA942751i,rTyrosine 3-monooxygen-Tyrosine 3-monooxygenase/tryptophan 5-ase/tryptophan 5-mono-monooxygenase activation protein, thetaoxygenase activationpolypeptideprotein, theta polypep-tide12616720AA997599GeneralESTs7783317AA892069zDipeptidyl peptidase 4Dipeptidyl peptidase 422851472AA925204oESTs, Highly similar to T08747hypothetical protein DKFZp586B0519.1 [ H.sapiens ]174191031AI030524GeneralESTs193352400X05300eGlycoprotein biosynthesisRibophorin IRibophorin I73841014AI029143dESTs115611772AI233182GeneralESTs149592288U03390GeneralRattus norvegicus Sprague Dawleyprotein kinase C receptor mRNA, complete cds211111633AI227832vESTs150851801AI233829k,oESTs, Weakly similar to PTD011 [ H.sapiens ]22840895AI009676GeneralESTs255982330U32575p12000648AA957319gButanoate metabolism,HHs:pyruvate dehydroESTs, Highly similar to ODPB RATGlycolysis/genase (lipoamide) betaPYRUVATE DEHYDROGENASE E1Gluconeogenesis, PyruvateCOMPONENT BETA SUBUNIT,metabolism, Valine,MITOCHONDRIAL PRECURSORleucine and isoleucine[ R.norvegicus ]biosynthesis140032259S65555GeneralGlutamate metabolism,Glutamate-cysteineGlutamate-cysteine ligase (gamma-Glutathione metabolismligase (gamma-glutamyl-glutamylcysteine synthetase), regulatorycysteine synthetase),regulatory16873851AI008015pThymopoietin (laminaThymopoietin (lamina associatedassociated polypeptide 2)polypeptide 2)254682238M94918q208792477X65296ucarboxylesterase 1carboxylesterase 119571451AI172143lHras-revertant gene 107Hras-revertant gene 10728111413AI171090o,bbButanoate metabolism,3-hydroxy-3-methylglutaryl3-hydroxy-3-methylglutaryl CoA lyaseSynthesis and degradationCoA lyaseof ketone bodies, Valine,leucine and isoleucinedegradation10988130AA819640bESTs34061070AI045083hESTs, Weakly similar to Y256_HUMANHYPOTHETICAl PROTEIN KIAA0256 [ H.sapiens ]15376278AA875206jRattus norvegicus mRNA for DA41, complete cds12371456AA924752ddZipper (leucine)Zipper (leucine) protein kinaseprotein kinase15512405X06150lGlycine, serine andGlycine methyltransferaseGlycine methyltransferasethreonine metabolism102491119AI059711mEST164841356AI169116GeneralESTs136701632AI227734e,GeneralESTs66041657AI229192nESTs, Weakly similar to EXRTcoagulation factor Xa [ R.norvegicus ]22690586AA945970uESTs, Weakly similar to KIAA0062 [ H.sapiens ]149371883AI237159zESTs, Highly similar to lipoic acidsynthetase [ H.sapiens ]140941836AI235377nESTs, Moderately similar to T12520hypothetical protein DKFZp434G173.1 [ H.sapiens ]21532370U75404aaESTs259281903AI639236f101871522AI176781GeneralESTs23029548AA944935e,GeneralESTs171052171M29358hribosomal protein S6ribosomal protein S61705014AA799466yPurine metabolismAdenylate kinase 2Adenylate kinase 23264727AA997779bbESTs, Moderately similar to A53184 mycfar upstream element-binding protein [ H.sapiens ]215312233M91595zInsulin-like growthInsulin-like growth factor binding protein 2factor binding protein 2169472412X08056hArginine and prolineGuanidinoacetateGuanidinoacetate methyltransferasemetabolism, Glycine,methyltransferaseserine and threoninemetabolism, Urea cycleand metabolism of aminogroups95271962D28560qRattus norvegicus mRNA for phosphodiesterase I225122158M22670yAlpha-2-macroglobulinAlpha-2-macroglobulin16364323AA892251d,pR.norvegicus mRNA for V1a arginine vasopressin receptor187701778AI233362aLysosomal associatedLysosomal associated membrane proteinmembrane protein 11 (120 kDa)(120 kDa)23471606AA955162tESTs113761301AI112863iESTs195601037AI030921aEST210431892AI237813tESTs, Weakly similar to KCCD RATCALCIUM/CALMODULIN-DEPENDENTPROTEIN KINASE TYPE II DELTACHAIN [ R.norvegicus ]217421497AI176172eESTs2230654AA957643rESTs20986370AA893242GeneralFatty acid metabolismAcyl CoA synthetase,Acyl CoA synthetase, long chainlong chain172372428X16145zGlycoprotein degradationFucasidase, alpha-L-1,Fucosidase, alpha-L-1, tissuetissue6366220AA858716uRattus norvegicus mRNA for signalpeptidase 21kDa subunit, complete cds39051247AI103403r,Generalpolypyrimidine tractpolypyrimidine tract binding proteinbinding protein232451610AI179570GeneralESTs20102292U05675b,nRattus norvegicus Sprague-Dawleyfibrinogen B beta chain mRNA, completecds1834934AA799744GeneralESTs23101020AI029969bESTs31671038AI031012bbESTs, Highly similar to CLPP MOUSEPUTATIVE ATP-DEPENDENT CLPPROTEASE PROTEOLYTIC SUBUNIT,MITOCHONDRIAL PRECURSOR[ M.musculus ]49401590AI178788krap7arap7a207152410X07259k,o,zFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily IVB, polypeptide 1Tryptophan metabolismfamily IVB, polypeptide 1254602232M89945eSterol biosynthesis,testis-specific farnesyltestis-specific farnesyl pyrophosphate synthetaseTerpenoid biosynthesispyrophosphate synthetase18128304AA891800GeneralESTs, Moderately similar to pyrophosphatase [ H.sapiens ]2446697AA965241xESTs, Highly similar to S32604 collagenalpha 2(VI) chain - mouse [ M.musculus ]149291384AI170353i,wRattus norvegicus ribosomal protein L21 mRNA, complete cds151811831AI235234l,GeneralESTs223871703AI230753cESTs, Highly similar to I3 protein [ H.sapiens ]149972052J03572t,yFolate biosynthesis,Tissue-nonspecific ALPTissue-nonspecific ALP alkaline phosphataseGlycerolipid metabolismalkaline phosphatase17614139AA848306qESTs167692517X98225bbRat mRNA for mitochondrial long-chainenoyl-CoA hydratase/3-hydroxyacyl-CoAdehydrogenase alpha-subunit ofmitochondrial trifunctional protein,complete cds156421560AI177503tR.norvegicus mRNA for histone H3.322370530AA944158d,k,GeneralESTs241381359AI169160GeneralESTs9451996D88666mRattus norvegicus mRNA for PS-PLA1, complete cds17896381AA893905GeneralESTs151931665AI229508General,ccESTs22689585AA945962aaESTs15888279AA875225aaGTP-binding proteinGTP-binding protein (G-alpha-i2)(G-alpha-i2)160251751AI232374aaHistone H1-0Histone H1-0158322262S68589iESTs, Moderately similar to NADH-ubiquinone oxidoreductase B14.5Bsubunit [ H.sapiens ]110971167AI071749aEST11021134AA819767eESTs103101536AI176961d,Generalribosomal protein,ribosomal protein, mitochondrial, L12mitochondrial, L1259261565AI177638j,GeneralESTs, Moderately similar to M phasephosphoprotein 10 [ H.sapiens ]16701866AI008838i,k,y,ccESTs, Weakly similar to LONN_HUMANMITOCHONDRIAL LON PROTEASEHOMOLOG PRECURSOR [ H.sapiens ]155381298AI112633GeneralProteasomeproteasome (prosome,proteasome (prosome, macropain)macropain) subunit,subunit, alpha type 6alpha type 623544280AA875233tProsaposin (sulfatedProsaposin (sulfated glycoprotein,glycoprotein, sphingo-sphingolipid hydrolase activator)lipid hydrolaseactivator)4896437AA924000GeneralESTs15759832AF089825Generalactivin beta Eactivin beta E69111987D85035d,General,wdihydropyrimidinedihydropyrimidine dehydrogenasedehydrogenase5902442X53428pglycogen synthaseglycogen synthase kinase 3 betakinase 3 beta19212010E01524g,GeneralP450 (cytochrome)P450 (cytochrome) oxidoreductaseoxidoreductase2670969AI012552GeneralESTs133931809AI234100Generalcysteine rich proteincysteine rich protein23521267AI104325GeneralESTs207881849AI236053iacyl-coenzyme A:acyl-coenzyme A:cholesterolcholesterol acyltrans-acyltransferaseferase15965260AA866404aESTs, Weakly similar to amyloid beta-peptide binding protein [ R.norvegicus ]68951381AI170067aaESTs164262482X70369dprocollagen, type III,procollagen, type III, alpha 1alpha 190671135AI070087GeneralESTs, Weakly similar to NUCL RAT NUCLEOLIN [ R.norvegicus ]187092179M32397uRibofiavin metabolismprostatic acid phos-prostatic acid phosphatase (rPAP)phatase (rPAP)244372157M22357aMyelin-associatedMyelin-associated glycoproteinglycoprotein13229222AA858760GeneralESTs115281404AI170766aaESTs239331863AI236376aESTs79181615AI179750cESTs254792248S45663h,dd21153922AI010632tRattus norvegicus cis-Golgi p28 (p28) mRNA, complete cds55791531AI176863bESTs209142162M23995g,xaldehyde dehydrogenasealdehyde dehydrogenase family 1, subfamily A4family 1, subfamily A4151352263S71021w,ccR.norvegicus mRNA for ribosomal proteinL624249878AI009273eFatty acid biosynthesisfatty acid synthasefatty acid synthase(path 1)183871891AI237731i,uGlycerolipid metabolismLipoprotein lipaseLipoprotein lipase263682032H34047bT-complex 1T-complex 118434448AA924413GeneralESTs, Weakly similar to dJ465N24.2.1 [ H.sapiens ]223751679AI230046GeneralESTs8121983D63704dPantothenate and CoAdihydropyrimidinasedihydropyrimidinasebiosynthesis, Pyrimidinemetabolism, beta-Alanine metabolism79371837AI235414aaESTs125811338AI145235iepo, itn_gamma,Janus kinase 2 (aJanus kinase 2 (a protein tyrosine kinase)iL3, iI6, Interact6-protein tyrosine1, pdgf, tpokinase)17161329AA892333Generalalpha-tubulinalpha-tubulin121562079K00996f,l,o,x,cc,ddFatty acid metabolism,cytochrome P450, 2b19cytochrome P450, 2b19Tryptophan metabolism145021747AI232339GeneralESTs238511313AI136862p,qESTs2336855AA800678bESTs176641813AI234496c,m,n,GeneralESTs17256299AA891739fESTs, Weakly similar to T22521hypothetical protein F52H3.5 -Caenorhabditis elegans [ C.elegans ]18712110AA818894iproteoglycan peptideproteoglycan peptide core proteincore protein22604563AA945578k,o,r,General,zputative peroxisomalputative peroxisomal 2,4-dienoyl-CoA2,4-dienoyl-CoAreductasereductase136191607AI179464j,qESTs17590357AA892851r,General,yESTs15592326U28504pRattus norvegicus Na+/Pi cotransporter-1 mRNA, complete cds245702240M95578vInterleukin 1 receptor,Interleukin 1 receptor, type Itype I21489200AA851443pESTs, Highly similar to similar to yeastSec6p, Swiss-Prot Accession NumberP32844 [ R.norvegicus ]3972522Y09332kacyl-CoA hydrolaseRattus norvegicus brain cytosolic acylcoenzyme A thioester hydrolase mRNA,complete cds, acyl-CoA hydrolase88081136AI070132j,General,aaESTs24200965AI012355bESTs1262783AB017044q,ddHepatocyte nuclearHepatocyte nuclear factor 3 gammafactor 3 gamma212541380AI170059GeneralESTs241631368AI169430f,gESTs, Moderately similar to AF151904 1CGI-146 protein [ H.sapiens ]180682272S79676vInterleukin 1betaInterleukin 1beta converting enzymeconverting enzyme8912360U66322m,GeneralRattus norvegicus dithiolethione-induciblegene-1 (DIG-1) mRNA, complete cds78581040AI043654wEST232971008AI028953GeneralESTs, Highly similar to S55054 Sm protein G [ H.sapiens ]11988118AA819193xESTs17962111L24207f,g,i,xCytochrome P450, sub-Cytochrome P450, subfamily IIIA,family IIIA, polypeptidepolypeptide 3318125865AI008787oESTs, Highly similar to S16788 probablereverse transcriptase - rat [ R.norvegicus ]1761318AA799511GeneralESTs17407958AI012145jESTs18829107AA818796l,GeneralESTs23387584AA945952bRNA binding proteinRNA binding protein p45AUF1p45AUF12320341AA799971General,zESTs, Weakly similar to S52675 probablemembrane protein YDR109c - yeast( Saccharomyces cerevisiae ) [ S.cerevisiae ]130041861AI236284kFatty acid metabolismHHs:fatty-acid-Rattus norvegicus mRNA for Acyl-CoACoenzyme A ligase, long-synthetase, complete cdschain 4121552034J00728f,g,k,l,x,cc,dd257012455X57986GeneralProtein kinase, cAMP-dependent, catalytic,alpha204272441X53378h,tRattus norvegicus ribosomal protein S13 (RPS13) mRNA, 3′ end3822424AA900863dESTs, Weakly similar to nuclear RNA helicase [ R.norvegicus ]15419919AI010476aESTs, Weakly similar to Chp [ R.norvegicus ]247282192M55532wRat Kupffer cell receptor mRNA, complete cds23355144AA848530GeneralESTs, Weakly similar to retinoblastomabinding protein [ R.norvegicus ]2677664AA963443e,GeneralESTs, Moderately similar to KIAA0822 protein [ H.sapiens ]208511997D88890bbacyl-CoA hydrolaseacyl-CoA hydrolase208951694AI230549e,GeneralESTs217401524AI176810bESTs22083178AA850587oESTs173861358AI169144GeneralESTs, Weakly similar to T23206hypothetical protein K01H12.1 -Caenorhabditis elegans [ C.elegans ]235951878AI236834jESTs165101322AI137583gInhibitor of DNA bindingInhibitor of DNA binding 2, dominant2, dominant negativenegative helix-loop-helix proteinhelix-loop-helix protein2486692AA964871General,x,yESTs3106710AA997109GeneralESTs38312525Y12635iR.norvegicus mRNA for vacuolaradenosine triphosphatase subunit B17092369AA893189d,f,i,General,ccRattus norvegicus glutathione reductase mRNA, complete cds241621362AI169279rESTs148401889AI237698i,l,uESTs48921052AI044292bESTs216631979D50436hferredoxin 1ferredoxin 1223031616AI179779GeneralESTs17127961AI012213bbESTs185412420X14671wESTs, Highly similar to RL26 RAT 60SRIBOSOMAL PROTEIN L26 [ R.norvegicus ]6873906AI010055aESTs139661723AI231421GeneralESTs137011684AI230180GeneralESTs, Weakly similar to T31425 C-terminal domain-binding protein rA4,splice form 2 - rat (fragment)[ R.norvegicus ]40051557AI177481GeneralProteasomeLow molecular massLow molecular mass polypeptide 2polypeptide 2213211805AI233902GeneralESTs254712243M96630u124501257AI103955mESTs, Weakly similar to T18653hypothetical protein B0035.3 -Caenorhabditis elegans [ C.elegans ]5256503AA926088gEST40431634AI227852vESTs1675678AA818089dESTs, Highly similar to glycyl-tRNA synthetase [ H.sapiens ]22119247AA859661bbESTs, Moderately similar to glutaminyl cyclase [ R.norvegicus ]115141438AI171855General,ddESTs, Moderately similar to unknown [ H.sapiens ]11844241AA859473GeneralRattus norvegicus VAMP5 mRNA, complete cds256702411X07648v247992007E01050tAlanine and aspartateAlanine-glyoxylateAlanine-glyoxylate aminotransferasemetabolism, Glycine,aminotransferase (Serine-(Serine-pyruvate aminotransferase)serine and threoninepyruvate aminotransferase)metabolism17580908AI010145jESTs, Highly similar to MCT-1 [ H.sapiens ]172272530Z36980tD-dopachrome tautomeraseD-dopachrome tautomerase11478507AA926231eESTs246462160M23264hAndrogen receptorAndrogen receptor (Testicular ferminization)(Testicular ferminization)17281949D16479k,o,zBile acid biosynthesis,HHs:hydroxyacyl-CoenzymeRat mRNA for mitochondrial long-chain 3-Fatty acid biosynthesisA dehydrogenase/3-ketoacyl-CoA thiolase beta-subunit of(path 2), Fatty acidketoacyl-Coenzyme Amitochondrial trifunctional protein,metabolism, Phenylalaninethiolase/enoyl-Coenzymecomplete ddsmetabolism, Valine,A hydratase (trifunc-leucine and isoleucinetional protein), betadegradationsubunit23768947AI011709GeneralESTs, Highly similar to S21977 Pm5 protein [ H.sapiens ]96971164AI071642xESTs75161172AI072183cESTs622015E06822c,GeneralRat mRNA for 20-alpha-hydroxysteroiddehydrogenase (20-alpha-HSD), completecds21729602AA946532oATP-binding cassette,ATP-binding cassette, sub-family D (ALD),sub-family D (ALD),member 3member 36619103AA818743qESTs, Highly similar to KIAA0728 protein [ H.sapiens ]129581547AI177155r,GeneralESTs, Highly similar to putative NAD(P)Hsteroid dehydrogenase [ M.musculus ]11997352AA892828ccButanoate metabolism,HHs:pyruvate dehydrogenaseESTs, Highly similar to ODPB RATGlycolysis/(lipoamide) betaPYRUVATE DEHYDROGENASE E1Gluconeogenesis, PyruvateCOMPONENT BETA SUBUNIT,metabolism, Valine,MITOCHONDRIAL PRECURSORleucine and isoleucine[ R.norvegicus ]biosynthesis14722323U26356uESTs, Highly similar to S10A RAT S-100PROTEIN, ALPHA CHAIN [ R.norvegicus ]17844621AA955927bESTs11608245AA859633jESTs225132161M23566b,yAlpha-2-macroglobulinAlpha-2-macroglobulin14479231AA858969pESTs, Moderately similar to I56526interleukin 1 receptor type I - rat [ R.norvegicus ]9102270S76511i,BcI2-associated X proteinBcI2-associated X protein17831955AI012017pRat major beta-globin mRNA, completecds3031824AF079864GeneralRattus norvegicus putative G-proteincoupled receptor RA1c mRNA, completecds15212210M63122GeneralTumor necrosis factorTumor necrosis factor receptorreceptor21251217AI102519lESTs, Moderately similar to DAP12 [ M.musculus ]254692239M94919q82321103AI059122aESTs134811834AI235352nESTs, Moderately similar to KIAA0966 protein [ H.sapiens ]21851238AA859330GeneralESTs189001784AI233570GeneralESTs, Highly similar to PSD8_HUMAN26S PROTEASOME REGULATORY SUBUNIT S14 [ H.sapiens ]21973545AA944840mESTs, Weakly similar to T19073hypothetical protein C08B11.9 -Caenorhabditin elegans [ C.elegans ]16311524AA943735dRattus norvegicus glycine transporter mRNA, complete cds149732105L19180rProtein tyrosine phos-Protein tyrosine phosphatate, receptor type Dphatase, receptor type, D187182180M33329GeneralAndrogen and estrogenRat senescence markerRat senescence marker protein 2A gene,metabolismprotein 2A gene, exonsexons 1 and 21 and 218027808AF039212f,p,qRattus norvegicus UDP-glucuronosyltransferase UGT1A7 mRNA, complete cds17788390AA899045lESTs, Highly similar to sid478p [ M.musculus ]14191229AA858924e,GeneralESTs49891473AI175087iESTs181072509X94242Generalribosomal protein L14ribosomal protein L14232991528AI176839r,GeneralESTs2097123AA799576aESTs, Highly similar to T46259hypothetical protein DKFZp761E0323.1 [ H.sapiens ]100021328AI137988rESTs, Highly similar to myosin X [ M.musculus ]206001540AI177004d,rButanoate metabolism,3-hydroxy-3-methyl-3-hydroxy-3-methylglutaryl-Coenzyme ASynthesis and degradationglutaryl-Coenzyme Asynthase 1of ketone bodies, Valine,synthase 1leucine and isoleucinedegradation94242255S61868gRyudocan/syndecan 4Ryudocan/syndecan 444772375U77829rESTs344867AI008865ySignal transducer andSignal transducer and activator ofactivator of transcrip-transcription 3tion 36331714AI231127r,yESTs21010478AA925306a,k,oESTs, Weakly similar to CLAT RATCHOLINE O-ACETYLTRANSFERASE [ R.norvegicus ]95281962D28560qRattus norvegicus mRNA for phosphodiesterase I49141291AI112086u,w,zESTs159962276S81478eRattus norvegicus protein tyrosinephosphatase mRNA, complete cds235791434AI171802General,zESTs131711332AI144722aaESTs, Moderately similar to I37356epithelial microtubule-associated protein,115K [ H.sapiens ]17952111L24207f,g,h,l,xCytochrome P450, sub-Cytochrome P450, subfamily IIIA,family IIIA, poly-polypeptide 3peptide 350911193AI073092GeneralESTs47311707AI230773GeneralESTs219331012AI029057b,GeneralESTs232752515X97443iintegral membrane proteinintegral membrane protein Tmp21-I (p23)Tmp21-I (p23)150291399AI170696cESTs, Weakly similar to development-related protein [ R.norvegicus ]170902368U73174lRattus norvegicus glutathione reductase mRNA, complete cds22971251AI103602GeneralESTs, Highly similar to SAP3 MOUSEGANGLIOSIDE GM2 ACTIVATORPRECURSOR [ M.musculus ]154271596AI78951jESTs15755777AB013112l,nneutral solute channelneutral solute channel aquaporin 9aquaporin 922602811AF044574k,o,bbputative peroxisomalputative peroxisomal 2,4-dienoyl-CoA2,4-dienoyl-CoAreductasereductase206512335U36992iCytochrom P450Cytochrom P45019086342AA892598nESTs18411306AI113289General,v,aaProtein-tyrosineProtein-tyrosine phosphatasephosphatase161482045J02752k,oFatty acid metabolismacyl-coA oxidaseacyl-coA oxidase4849431AA901155GeneralRattus norvegicus CDK105 mRNA6402278S82229bPurine metabolismNatriuretic peptideNatriuretic peptide receptor A/Guanylatereceptor A/Guanylatecyclase Acyclase A122871228AI102751aaDNA polymerase, PurineHHs:polymerase (DNAESTs, Highly similar to DPD2_HUMANmetabolism,directed), delta 2,DNA POLYMERASE DELTA SMALLPyrimidine metabolismregulatory subunitSUBUNIT [ H.sapiens ](50kD)218161717AI231217gESTs, Highly similar to S61A RATPROTEIN TRANSPORT PROTEINSEC61 ALPHA SUBUNIT [ R.norvegicus ]3833193AA851255jESTs, Highly similar to HSPC017 [ H.sapiens ]7053939AI011467b,mESTs216232389V01217hcytoplasmic beta-actincytoplasmic beta-actin146761817AI234615b,GeneralRattus norvegicus MLS2s mRNA formelastatin like 2, complete cds3997494AA925771lESTs, Moderately similar to T12483hypothetical protein DKFZp564B0769.1 [ H.sapiens ]25139765AB005743bbCD36 antigen (collagenCD36 antigen (collagen type I receptor,type I receptor,thrombospondin receptor)thrombospondin receptor)243881873AI236772jESTs18442182M33962v,aaProtein-tyrosineESTs, Protein-tyrosine phosphatasephosphatase212601804AI233885xESTs, Weakly similar to AF151835 1 CGI-78 protein [ H.sapiens ]4527346AA892774c,vESTs11635246AA859645cattractinattractin167044AA686132General101842028H33426e,GeneralESTs127921532AI176883j,m,nESTs, Highly similar to AF151825 1 CGI-67 protein [ H.sapiens ]142751566AI177748aaESTs18685725AA997746oFatty acid metabolismdodecenoyl-Coenzyme Adodecenoyl-Coenzyme A delta isomerasedelta isomerase (3,2(3,2 trans-enoyl-Coenyme A isomerase)trans-enoyl-Coenyme A145011486AI175778vESTs184011266AI104300f,Generalproteasome (prosome,Rattus norvegicus proteasome z subunitmacropain) subunit,mRNA, complete cdsbeta type, 787841237AI103007General,bbESTs, Moderately similar to unknown [ H.sapiens ]40031930D10757eProteasomeLow molecular massLow molecular mass polypeptide 2polypeptide 2169532011E01534hribosomal protein S15ribosomal protein S1569121987D85035zdihydropyrimidinedihydropyrimidine dehydrogenasedehydrogenase7274995AI013715kESTs, Moderately similar to BMP6 RATBONE MORPHOGENETIC PROTEIN 6PRECURSOR [ R.norvegicus ]144621198AI100871GeneralESTs, Weakly similar to T20358hypothetical protein D2030.8 -Caenorhabditis elegans [ C.elegans ]13975177AA850450yRattus norvegicus mRNA for class I beta-tubulin, complete cds207781990D85844grabaptin 5rabaptin 5148271885AI237404vESTs, Moderately similar to PKL2 RATPROTEIN KINASE C-LIKE 2 [ R.norvegicus ]253252087K03045n49261471AI175034GeneralESTs, Weakly similar to T15846hypothetical protein C56C10.7 -Caenorhabitis elegans [ C.elegans ]4267239AA859412mESTs, Highly similar to NICA_MOUSENICASTRIN PRECURSOR [ M.musculus ]165652383U91847np38 mitogen activatedp38 mitogen activated protein kinaseprotein kinase21305367AA893082GeneralESTs22867331AA892353GeneralESTs, Weakly similar to T33520hypothetical protein T10B11.6 -Caenorhabditis elegans [ C.elegans ]15090235AA859224General,aaRattus norvegicus mRNA for NAD+-specific isocitrate dehydrogenase a-subunit, complete cds2342679AA964336tESTs115531706AI230765mESTs, Weakly similar to P24 RAT COP-COATED VESICLE MEMBRANEPROTEIN P24 PRECURSOR[ R.norvegicus ]3044722AA997701nEST187771230AI102788jESTs239831672AI229708GeneralESTs, Moderately similar toNADC_HUMAN NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE[ H.sapiens ]7756359AA892864zESTs16032491X78855General,xOrganic cation trans-Organic cation transporterporter9309668AA963794GeneralESTs23637614AA955587aESTs, Highly similar to CST1_HUMANCLEAVAGE STIMULATION FACTOR, 50 KD SUBUNIT [ H.sapiens ]11742041J02657pFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily IICTryptophan metabolismfamily IIC (mephenytoin(mephenytoin 4-hydroxylase)4-hydroxylase)15829801AF034577bbpyruvate dehydrogenaseRattus norvegicus pyruvatekinase, isoenzyme 4dehydrogenase kinase isoenzyme 4(PDK4) mRNA, complete cds175541988D85100ksolute carrier family 27solute carrier family 27 (fatty acid(fatty acid transporter),transporter), member 2member 229702139M14775hFatty acid metabolism,cytochrome P450, 2c39cytochrome P450, 2c39Tryptophan metabolism103071254AI103695mribosome associatedribosome associated membrane protein 4membrane protein 415391907AI010083k,lRat mRNA for HBP23 (heme-bindingprotein 23 kDa), complete cds60571450AI172102b,GeneralESTs, Weakly similar to T33238hypothetical protein T10H9.3 -Caenorhabditis elegans [ C.elegans ]186871389AI170568k,oFatty acid metabolismdodecenoyl-Coenzyme ARat mRNA for delta3, delta2-enoyl-CoAisomerase (3,2 trans-isomerase, dodecenoyl-Coenoyl-Coenzyme A deltaenoyl-Coenyme Aisomerase (3,2 trans-enoyl-Coenyme Aisomerase)35371208AI101690edishevelled 1dishevelled 122914447AA924335l,GeneralESTs6471180AA850706GeneralESTs4801425AA900981GeneralEST70221494AI176041GeneralESTs, Highly similar to pirin [ H.sapiens ]234241625AI180068bAlanine and aspartateHHs:alanyl-tRNA synthetaseESTs, Highly similar to SYA_HUMANmetabolism, Aminoacyl-ALANYL-TRNA SYNTHETASE [ H.sapiens ]tRNA biosynthesis17742259AA866302q,tPhenylalanine metabolism,4-hydroxyphenylpyruvic4-hydroxyphenylpyruvic acid dioxygenaseTyrosine metabolismacid dioxygenase21090764AB005547Generalaquaporin 8aquaporin 8149391645AI228557General,aaESTs190351866AI236576GeneralESTs, Highly similar to RB1B RAT RAS-RELATED PROTEIN RAB-1B [ R.norvegicus ]238262337U38180asolute carrier family 19solute carrier family 19 (sodium/hydrogen(sodium/hydrogenexchanger), member 1exchanger), member 116007818AF062594i,Generalnucleosome assemblyRattus norvegicus nucleosome assemblyprotein 1-like 1protein mRNA, complete cds9349957AI012143a,gESTs, Highly similar to KIAA0242 protein [ H.sapiens ]204642154M20406q,ccRat cytochrome P450IIB3 (P450IIB subfamily) mRNA, complete cds17044909AI010173bbESTs18502083K02814a,b,qT-kininogenT-kininogen248492253S60953xneurotrophic tyrosine,neurotrophic tyrosine kinase, receptor, type3kinase, receptor, type 345922040J02646a,General,yeukaryotic translationeukaryotic translation tnitiation factor 2,initiation factor 2,subunit 1 (alpha)subunit 1 (alpha)175331919D00636e,GeneralAminosugars metabolismHHs:diaphorase (NADH)R at NADH-cytochrome b-S reductase(cytochrome b-5 reductase)mRNA, complete cds192211245AI103374jESTs, Highly similar to homolog of theAspergillus nidulans sudD gene product [ H.sapiens ]18674165AA849603GeneralESTs3866365AA893074lESTs17684330AA892345General,uRat mRNA for dimethylglycinedehydrogenase (EC number 1.5.99.2)106261945D14988hRat hydroxysteroid sulfotransferase mRNA, complete cds23452477AA925289eESTs, Moderately similar to dJ167A19.4 [ H.sapiens ]23839636AA956684mESTs203112345U52045p,qHomeobox gene PemHomeobox gene Pem201612447X54686n,vjun B proto-oncogenejun B proto-oncogene1206039AA799890g,x,ccESTs146191880AI236989aaESTs220062387U96490wRattus norvegicus liver mRNA, complete cds16304768AB008424aRat cytochrome P-450 IID3 mRNA, complete cds213261678AI230013jESTs173491621AI179987General,bbESTs, Highly similar to HG17 RATNONHISTONE CHROMOSOMAL PROTEIN HMG-17 [ R.norvegicus ]23243203AA851803g,i,x,y,ddESTs8594976AI012932pESTs17496505AA926109mESTs225981320AI137506k,wESTs, Weakly similar to SPI-2 serineprotease inhibitor [ R.norvegicus ]309263AA866460e,wESTs170491462AI172417c,d,eESTs, Weakly similar to T20356hypothetical protein D2030.5 -Caenorhabditis elegans [ C.elegans ]3895383AA894029i,uESTs23159479AA925318GeneralI-kappa-B-betaI-kappa-B-beta255252264S72505h,w,xGlutathione metabolismGlutathione-S-transfer-Glutathione-S-transferase, alpha type (Ya)ase, alpha type (Ya)12108154AA848963GeneralESTs, Moderately similar to DNA-REPAIRPROTEIN COMPLEMENTING XP-CCELLS HOMOLOG [ M.musculus ]182391617AI179942cESTs14262531Z48225yR.norvegicus mRNA for protein synthesisinitiation factor eIF-2B delta subunit19433135AA819776zESTs, Weakly similar to HS9B RAT HEATSHOCK PROTEIN HSP 90-BETA [ R.norvegicus ]116441832AI235282l,GeneralESTs, Moderately similar to AM2 receptor [ M.musculus ]190571829AI235094bcortactin isoform Bcortactin isoform B122231417AI171266Generaltranslocase of innertranslocase of inner mitochondrialmitochondrial membrane 8membrane 8 (yeast) homolog A(yeast) homolog A5175111AA818951h,i,u,wpyruvate kinase 3Rat mRNA for pituitary pyruvate kinase39451766AI232719fESTs57891061AI044718GeneralESTs, Weakly similar to A24264 proline-rich protein MP2 - mouse [ M.musculus ]92121154AI071098dESTs22142518AA943066GeneralESTs, Weakly similar to p68 RNA helicase [ R.norvegicus ]6365393AA899163e,uRattus norvegicus mRNA for signalpeptidase 21kDa subunit, complete cds13792222M83676r,vRAB12, member RASRAB12, member RAS oncogene familyoncogene family16496706AA996955gESTs15848844AI007820f,oESTs, ESTs, Highly similar to HS9B RATHEAT SHOCK PROTEIN HSP 90-BETA [ R.norvegicus ]207792142M15185qMethionine metabolism,5-adenosylhomocysteineS-adenosylhomocysteine hydrolaseSelenoamino acid meta-hydrolasebolism162741924D10261n,xalpha 2 HS-glycoproteinalpha 2 HS-glycoprotein alpha 2 (fetuin)alpha 2 (fetuin)21128145AA848555iESTs145201589AI178785GeneralESTs, Weakly similar to coding sequenceof pol [ R.norvegicus ]208722436X51707f,wribosomal protein S19ESTs, Highly similar to RS19 RAT 40SRIBOSOMAL PROTEIN S19 [ R.norvegicus ]250562134M13234f,x,cc,dd250662268S75280dd184531952D17370uCysteine metabolism,CTL target antigenCTL target antigenMethionine metabolism,Nitrogen metabolism,Selenoamino acidmetabolism1557756AB000216GeneralRattus norvegicus mRNA for CCA3, complete cds177582089K03249k,o,w,zRat peroxisomal enoyl-CoA: hydrotase-3-hydroxyacyl-CoA bifunctional enzyme mRNA, complete cds94691192AI073023aESTs123431724AI231433jESTs207052008E01184d,f,g,q,bb,cc,ddFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily I (aromaticTryptophan metabolismfamily I (aromaticcompound-inducible), member A2 (Q42,compound-inducible),form d)member A2 (Q42, form d)56751066AI045026bESTs235381227AI102727i,jsolute carrier familysolute carrier family 20 (phosphate20 (phosphate transpor-transporter), member 1ter), member 1102602277S81497pESTs31341628AI180292wESTs, Moderately similar to YLHUA serumamyloid A2 protein precursor [ H.sapiens ]93251184AI072617General,aaEST16125833AF090134General,cclin-7-BaRattus norvegicus lin-7-Bb mRNA, complete cds14616487AA925559aaESTs1915013AA799461GeneralESTs, Weakly similar to EP15 MOUSEEPIDERMAL GROWTH FACTORRECEPTOR SUBSTRATE SUBSTRATE15 [ M.musculus ]257472496X81448w111532234M91652General,ccGlutamate metabolism,Glutamine synthetaseGlutamine synthetase (glutamate-Nitrogen metabolism(glutamate-ammoniaammonia ligase)ligase)22607564AA945580GeneralESTs, Weakly similar to ARG2 RATARGINASE II PRECURSOR [ R.norvegicus ]151412003D90265aProteasomeproteasome (prosome,proteasome (prosome, macropain)macropain) subunit,subunit, alpha type 1alpha type 119410378AA893667yESTs, Moderately similar to AC006978 1supported by human and rodent ESTs [ H.sapiens ]258022013E02315wCalmodulin 1 (phos-Calmodulin 1 (phosphorylase kinase, delta)phorylase kinase, delta)256442376U77931t,v5496825AF080468g,General,bbglucose-6-phosphatase,glucose-6-phosphatase, transport proteintransport protein 1115097882AI009405GeneralInsulin-like growthInsulin-like growth factor-binding proteinfactor-binding protein(IGF-BP3)(IGF-BP3)72521827AI235058GeneralESTs, Highly similar to mitochondrial outermembrane protein [ M.musculus ]4689405AA899899ccESTs250572200M58495l,q,General7199980AI013044r,GeneralESTs21502004D90404dCathepsin C (dipeptidylCathepsin C (dipeptidyl peptidase I)peptidase I)56961072AI045116General,yESTs4172483AA925514iESTs231821710AI230981GeneralESTs4723836AF093773tRattus norvegicus cytosolic malatedehydrogenase (Mdh) mRNA, complete cds216832211M65149c,m,General,vCCAAT/enhancerbinding,CCAAT/enhancerbinding, protein (C/EBP)protein (C/EBP) deltadelta21750892AI009663oESTs151731731AI231846qESTs3148847AI007881General,aaESTs6295131AA819672GeneralEST87151132AI069920i,j,GeneralESTs73121561AI177543ddESTs, Weakly similar to T32252hypothetical protein T15B7.2 -Caenorhabditis elegans [ C.elegans ]3535753AA999135GeneralESTs151071774AI233220pESTs, Highly similar to RS18_HUMAN40S RIBOSOMAL PROTEIN S18 [ R.norvegicus ]136822121L38482GeneralRattus norvegicus serine protease gene, complete cds67802068J05029kFatty acid metabolismAcyl Coenzyme A dehy-Acyl Coenzyme A dehydrogenase, longdrogenase, long chainchain5752425X15734a,gMethionine metabolism,S - adenosylmethionineS - adenosylmethionine synthetaseSelenoamino acid meta-synthetasebolism207722355U60882yheterogeneous nuclearheterogeneous nuclear ribonucleoproteinsribonucleoproteinsmethyltransferase-like 2 ( S. cerevisiae )methyltransferase-like257992016E12625e131852317U23055pcarcinoembryonic antigen-carcinoembryonic antigen-related cellrelated cell adhesionadhesion moleculemolecule2387830AA799686jESTs21103802AF034582rvesicle associatedRattus norvegicus vesicle associatedproteinprotein (VAP1) mRNA, complete cds1838916AA799498yBrain natriuretic factorBrain natriuretic factor71971441AI171962vAnnexin 1 (p35)Annexin 1 (p35) (Lipocortin 1)(Lipocortin 1)204622153M20156wribosomal protein L18ribosomal protein L18246442056J03637pHistidine metabolism,Aldehyde dehydrogenasealdehyde dehydrogenase family 3,Phenylalanine metabolism,class 3subfamily A1Tyrosine metabolism231491415AI171213GeneralESTs, Highly similar to putative ATP/GTP-binding protein [ H.sapiens ]16034863AI008701ddESTs22631156AA849030jESTs213551277AI105094k,o,bbESTs225661545AI177122c,vESTs50071858AI236229pESTs1742064J04197rFructose and mannose6-Phosphofructo-2-kinase/6-Phosphofructo-2-kinase/fructose-2,6-metabolismfructose-2,6-bisphos-bisphosphatase 1 (liver and muscle)phatase 1 (liver andmuscle)18725799AF029240GeneralRattus norvegicus MHC class lb RT1.S3 (RT1.S3) mRNA, partial cds3903409AA899986k,bbpolypyrimidine tractpolypyrimidine tract binding proteinbinding protein16762816AF059530hprotein arginine N-methyl-Rattus norvegicus protein arginine N-transferase 3(hnRNPmethyltransferase 3 (PRMT3) mRNA,methyltransferase S.complete cdscerevisiae )-like 317972464X62086f,x,cc,ddCytochrome P450, sub-Cytochrome P450, subfamily IIIA,family IIIA,polypeptide 3, Rattus norvegicus Spraguepolypeptide 3Dawley testosterone 6-beta-hydroxylase,cytochrome P450/6-beta-A, (CYP3A2)mRNA, complete cds866195AA818604f,qHeat shock protein 70-1Heat shock protein 70-120804946AI011684lCarbon fixation, Pentosetransketolasetransketolasephosphate cycle156841424AI171535r,GeneralESTs, Weakly similar to 100K RAT 100 KD PROTEIN [ R.norvegicus ]19187191AA851230General,aaESTs, Weakly similar to T28050hypothetical protein ZK856.11 -Caenorhabditis elegans [ C.elegans ]600279AA818101GeneralEST623496AA818612aaESTs, Highly similar to S53583 splicing factor SF3a60 [ H.sapiens ]20792100L14462Generalrelated to Drosophilarelated to Drosophila groucho genegroucho gene18906341AA892561lESTs, Moderately similar to PTD012 [ H.sapiens ]92681176AI072375kESTs, Highly similar to HIV-Nefassociated acyl CoA thioesterase [ H.sapiens ]4154887AI009467tESTs160122469X62875iESTs, Highly similar to HIGH MOBILITYGROUP PROTEIN HMG-Y [ M.musculus ]192871752AI232379hpdgfPlatelet-derived growthPlatelet-derived growth factor receptorfactor receptor alphaalpha178942320U25264rSelenoprotein W muscle 1Selenoprotein W muscle 19143744AA998450cc,ddESTs34981131AI069912tESTs4330104AA818747c,dESTs6237123AA819288d,GeneralESTs16883714AA997345c,dESTs, Weakly similar to nitrilase homolog 1 [ M.musculus ]155821746AI232320kRat mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase mRNA, complete cds66381321AI137579GeneralESTs147381539AI176993g,GeneralESTs16006818AF062594i,rnucleosome assemblyRattus norvegicus nucleosome assemblyprotein 1-like 1protein mRNA, complete cds5094470AA925165zESTs244272050J03170yTranscription factor 1,Transcription factor 1, hepatic; LF-B1,hepatic nuclear factorhepatic; LF-B1, hepatic nuclear factor (HNF1): albumin(HNF1)proximal factor, also TCF121903562AA945571q,x,cc,ddFatty acid metabolism,cytochrome P450, 2c37cytochrome P450, 2c37Tryptophan metabolism15357926AI010803qESTs, Moderately similar toTESTOSTERONE-REGULATED RP2 PROTEIN [ M.musculus ]65441212AI102064bESTs, Weakly similar to AF147718 1glycine decarboxylase [ R.norvegicus ]74031015AI029212c,GeneralEST6060102AA818702yESTs6132114AA819055dESTs, Weakly similar to G35070apolipoprotein H-related protein 13G1 -mouse [ M.musculus ]188311268AI104357GeneralESTs, Highly similar to ATRTC actin beta -rat [ R.norvegicus ]60721647AI228630f,g,yESTs, Weakly similar to T20360hypothetical protein D2030.9b -Caenorhabditis elegans [ C.elegans ]1962755AB000199GeneralRattus norvegicus cca2 mRNA, complete cds3572290U04835fCAMP responsive elementCAMP responsive element modulatormodulator2098026AA799633z,bbESTs22847436AA923982bbESTs, Highly similar to ATP-specificsuccinyl-CoA synthetase beta subunit [ M.musculus ]14234230AA858928GeneralESTs, Moderately similar to Unknown [ H.sapiens ]19085342AA892598n,yESTs257462495X80778y5382510X94246hPax-8 proteinPax-8 protein18192785AF000899jRattus norvegicus nucleoporin p58 mRNA, complete cds109371681AI230131aaESTs, Weakly similar to AF151834 1 CGI-76 protein [ H.sapiens ]20797446AA924310GeneralESTs, Highly similar to A49630 ubiquitinconjugating enzyme [ H.sapiens ]175072053J03583tclathrin, heavy poly-clathrin, heavy polypeptide (Hc)peptide (Hc)15679929AI011058GeneralESTs66971079AI045340tESTs11467430AA901069a210522143M15481d,GeneralRat insulin-like growth factor-I mRNA, 3′end24654125AA819333a,GeneralSprague-Dawley (clone LRB2) RAB16 mRNA, complete cds18524587AA946017r,GeneralESTs107101030AI030494p,GeneralESTs41901541AI177016GeneralESTs, Highly similar to similar toSchizosaccharomyces pombe splicing factor [ H.sapiens ]13712325U27319aAminosugars metabolism,Hexokinase 1Hexokinase 1Fructose and mannosemetabolism, Galactosemetabolism, Glycolysis/Gluconeogenesis, Starchand sucrose metabolism2666658AA962942ddESTs232281838AI235446zESTs19936634AA956517Generalceroid-lipofuscinosis,ceroid-lipofuscinosis, neuronal 2neuronal 2210632000D89983yornithine decarboxylaseornithine decarboxylase antizyme inhibitorantizyme inhibitor50061677AI229908pESTs19665797AF022819hputative potassiumputative potassium channel TWIKchannel TWIK4186556AA945169n,xTransthyretin (prealbumin,Transthyretin (prealbumin, amyloidosisamyloidosis type I),type I), solute carrier family 25solute carrier family 25(mitochondrial carrier; citrate transporter)(mitochondrial carrier;member 1citrate transpo1718751AA800315z,bbESTs, Highly similar to PxF protein [ M.musculus ]187421278AI105131k,oESTs, Highly similar to AF189764 1alpha/beta hydrolase-1 [ M.musculus ]4900440AA924024jESTs153821459AI172302ccESTs, Weakly similar to S43056hypothetical protein - mouse [ M.musculus ]22481383AI170332mESTs, Highly similar to T18295 Ap-3adaptor complex beta3A chain - mouse [ M.musculus ]10532891AI009602GeneralESTs66731054AI044325Generalcadherin 2, type 1,cadherin 2, type 1, N-cadherin (neuronal)N-cadherin (neuronal)22018858AI008309bESTs, Moderately similar to PIM1 RATPROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASEPIM-1 [ R.norvegicus ]5108475AA925264GeneralESTs147681845AI235912vESTs, Weakly similar to hypothetical protein [ H.sapiens ]71861187AI072833zESTs2109252AA800380General,uESTs, Weakly similar toCORTICOSTEROID 11-BETA-DEHYDROGENASE, ISOZYME 1[ R.norvegicus ]228661792AI233754b,q,General,aaprolactin regulatoryprolactin regulatory element bindingelement binding182051062AI044836General,wESTs, Weakly similar to AF 165892 1 RNAbinding protein SiahBP [ R.norvegicus ]114851833AI23548GeneralESTs, Weakly similar to polycomb-groupprotein [ R.noivegicus ]140701762AI232649oESTs, Weakly similar to I52328 ubiqultin/ribosomal protein S27a - rat [ R.norvegicus ]59441635AI227892aaESTs13122175M31788eESTs, Highly similar to PGK2 RATPHOSPHOGLYCERATE KINASE,TESTIS SPECIFIC [ R.norvegicus ], Rat X-chromosome linked phosphoglyceratekinase mRNA, complete cds4590350AA892778d,GeneralESTs2939705AA996885y,ccESTs, Moderately similar to EBI-1 ligandchemokine [ M.musculus ]12542716AA997499c,jESTs, Highly similar to 0506206A histone H2B [ R.norvegicus ]2569695AA965122f,r,yESTs, Weakly similar to T24832hypothetical protein T11F9.11 -Caenorhabditis elegans [ C.elegans ]99631073AI045144j,GeneralEST, Moderately similar to CO6_HUMANCOMPLEMENT COMPONENT C6 PRECURSOR [ H.sapiens ]148821916D00362ccEsterase 2Esterase 24067461AA924813oESTs131181315AI137292ccESTs23889334AA892520iESTs17468337AA892545eESTs, Highly similar to multi-membranespanning polyspecific transporter [ M.musculus ]40931733AI232001General,ccGlycolysis/HHs:phosphoglycerateR.norvegicus phosphoglycerate mutase BGluconeogenesismutase 1 (brain)isozyme (PGAM) mRNA, complete cds10108845AI007857jHrsHrs18669630AA956453lESTs, Highly similar to AF139209 1 OB-receptor gene related protein [ R.norvegicus ]16126833AF090134Generallin-7-BaRattus norvegicus lin-7-Bb mRNA, complete cds9582367U72741tLectin, galactose binding,Lectin, galactose binding, soluble 9 (Galectin-9)soluble 9 (Galectin-9)23678830AF087037i,jB-cell translocationB-cell translocation gene 3gene 33412504X89383ddR.norvegicus mRNA for SNF1-relatedkinase23348265AA874813hhypertension-relatedhypertension-related proteinprotein78701203AI101319GeneralESTs22972779AB015946rRattus norvegicus mRNA for tubulin, complete cds190311145AI070532j,uT-cell death associatedT-cell death associated genegene154961750AI232370GeneralESTs, Weakly similar to DPSD_CAEELPUTATIVE PHOSPHATIDYLSERINEDECARBOXYLASE PROENZYME[ C.elegans ]136181700AI230724GeneralRattus norvegicus phosphoinositidephosphatase SAC1 mRNA, complete cds19282303U10357Generalpyruvate dehydrogenasepyruvate dehydrogenase kinase 2 subunitkinase 2 subunit p45p45 (PDK2)(PDK2)218421458AI172293eRattus norvegicus mRNA for RANP-1, complete cds1902299U09540pFatty acid metabolism,Cytochrome P450 1b1Cytochrome P450 1b1Tryptophan metabolism172101790AI233746GeneralESTs, Weakly similar to SC14_HUMANSEC14-LIKE PROTEIN [ H.sapiens ]18165324AA892259vESTs, Moderately similar to ICSB MOUSEINTERFERON CONSENSUSSEQUENCE BINDING PROTEIN[ M.musculus ]15383610AA955358l,o,GeneralESTs5213493AA925767oESTs205892409X06916wProtein 9 Ka homologousProtein 9 Ka homologous to calcium-to calcium-binding proteinbinding protein859794AA818593h,u,ddphosphatidate phospho-phosphatidate phosphohydrolase type 2hydrolase type 2150041830AI235224wRattus norvegicus tissue inhibitor ofmetalloproteinase-1 (TIMP1), mRNA, complete cds16367360AA892888p,q,ccEST73511985D83036hhomeo box, msh-like 1homeo box, msh-like 15102473AA925211xEST13633962AI012335Generalactivating transcriptionactivating transcription factor ATF-4factor ATF-41521359AA800908iESTs232241349AI146033GeneralRattus norvegicus small zinc finger-likeprotein (TIM9a) mRNA, partial cds183012332U33500ddRattus norvegicus retinol dehydrogenase type II mRNA, complete cds29131742AI232272GeneralESTs, Weakly similar to T25417hypothetical protein T28D6.9 -Caenorhabditis elegans [ C.elegans ]31431754AI232408l,General,xESTs58991379AI170038m,uESTs19852589AA946053oESTs1216088AA818412l,x,ddFatty acid metabolism,cytochrome P450, 2b19cytochrome P450, 2b19Tryptophan metabolism26147989AI013387aa151742351U59809iInsulin-like growthInsulin-like growth factor 2 receptorfactor 2 receptor21980374AA893454b,yESTs18182524Y11283a,b,k,n,ddinter-alpha-inhibitorinter-alpha-inhibitor H4 heavy chainH4 heavy chain209132162M23995xaldehyde dehydrogenasealdehyde dehydrogenase family 1, subfamily A4family 1, subfamily A416724185AA850987ddESTs18902284AA875390cESTs, ESTs, Highly similar to thioredoxin-related protein [ M.musculus ]18726799AF029240General,bbRattus norvegicus MHC class Ib RT1.S3 (RT1.S3) mRNA, partial cds248002187M35270tAlanine and aspartateAlanine-glyoxylate amino-Alanine-glyoxylate aminotransferasemetabolism, Glycine,transferase (Serine-(Serine-pyruvate aminotransferase)serine and threoninepyruvate aminotransferase)metabolism6440233AA859130GeneralESTs, Moderately similar to P2CGMOUSE PROTEIN PHOSPHATASE 2CGAMMA ISOFORM [ M.musculus ]151461538AI176969GeneralESTs22051397AA899498bbESTs, Weakly similar to T26581hypothetical protein Y32B12A.3 -Caenorhabditis elegans [ C.elegans ]4375380AA893869iESTs, Weakly similar to T16084hypothetical protein F16H11.1 -Caenorhabditis elegans [ C.elegans ]235762485X72757q,tOxidative phosphory-Cytochrome c oxidaseCytochrome c oxidase subunit VIa (liver)lationsubunit VIa (liver)183177AA799326bbCD36 antigen (collagenCD36 antigen (collagen type I receptor,type I receptor,thrombospondin receptor)thrombospondin receptor)1045757AB000280iRattus norvegicus mRNA forpeptide/histidine transporter, complete cds2267884AI009450bbESTs, Highly similar to HIRA-interacting protein [ M.musculus ]91951171AI072118ddEST115491740AI232174jESTs141091775AI233227GeneralESTs185291699AI230716GeneralESTs167031603AI179300f,k,o,x,yESTs, Weakly similar to LONN_HUMANMITOCHONDRIAL LON PROTEASEHOMOLOG PRECURSOR [ H.sapiens ]45611236AI102927p,qglutaredoxinglutaredoxin101901109AI059342aESTs, Weakly similar to death inducer-obliterator-1 [ M.musculus ]6390224AA85821GeneralESTs16022374U76379General,xOrganic cation transporterOrganic cation transporter12331597AA946466eRattus norvegicus membrane-boundaminopeptidase P mRNA, complete cds137991488AI175871gESTs221391512AI176548bbESTs, Weakly similar to T32252hypothetical protein T15B7.2 -Caenorhabditis elegans [ C.elegans ]6381223AA858768uESTs17290302AA891785zCitrate cycle (TCA cycle),HMm:isocitrate dehydro-ESTs, Weakly similar to IDHC RATGlutathione metabolism,genase 2 (NADP+),ISOCITRATE DEHYDROGENASEReductive carboxylatemitochondrial[ R.norvegicus ]cycle CO2 fixation)22052397AA899498fESTs, Weakly similar to T26581hypothetical protein Y32B12A.3 -Caenorhabditis elegans [ C.elegans ]17530670AA963839GeneralAminosugars metabolismHHs:diaphorase (NADH)Rat NADH-cytochrome b-5 reductase(cytochrome b-5mRNA, complete cdsreductase)18383596AA946421tESTs, Highly similar to transcription factor TFEB [ M.musculus ]23520609AA955305pESTs143031716AI231159vESTs, Highly similar to KIAA1049 protein [ H.sapiens ]7281997AI013755gESTs, Highly similar to KIAA0066 [ H.sapiens ]145561893AI237820iESTs23468502AA926067rESTs100731093AI058515zEST402285U02096ofatty acid bindingfatty acid binding protein 7, brainprotein 7, brain2457686AA964752k,oEST4751800AI233828m,General,uESTs, Moderately similar to LYSOSOMALALPHA-MANNOSIDASE PRECURSOR [ M.musculus ]23863615AA955628ddESTs, Moderately similar to KIAA0710 protein [ H.sapiens ]140811771AI233164mESTs243231274AI104798General,ccESTs, Moderately similar to GTM1 RATGLUTATHIONE S-TRANSFERASE YB1 [ R.norvegicus ]133691956D21132General,yRat mRNA for phosphatidylinositol transferprotein (beta isoform), complete cds97951168AI071989a,bESTs, Weakly similar to NPA1 MOUSENEURONAL PAS DOMAIN PROTEIN 1 [ M.musculus ]171171639AI228042f,lESTs, Weakly similar to AC007080 2 NG38 [ M.musculus ]10015827AF083269c,uActin-related proteinActin-related protein complex 1bcomplex 1b58481354AI168994mESTs210382051J03190f,xGlycine, serine andaminolevulinic acidaminolevulinic acid synthase 1threonine metabolismsynthase 18111983D63704d,e,zPantothenate and CoAdihydropyrimidinasedihydropyrimidinasebiosynthesis, Pyrimidinemetabolism, beta-Alaninemetabolism109991155AI071110GeneralEST125771283AI111344a,Generalcyclin Hcyclin H60552132M12337l,bbPhenylalanine, tyrosinePhenylalaninePhenylalanine hydroxylaseand tryptophan bosynthesishydroxylase71611779AI233407i,j,General,aaESTs, Weakly similar to S44853 K12H4.3protein - Caenorhabditis elegans [ C.elegans ]22755593AA946323p,qESTs15371277AA875205General,tESTs, Highly similar to IF39_HUMANEUKARYOTIC TRANSLATIONINITIATION FACTOR 3 SUBUNIT 918991553AA945082General,ccGlutathione metabolismGlutathione-S-transfer-Glutathione-S-transferase, alpha typease, alpha type (Yc?)(Yc?)7225993AI013657e,General,ddESTs183968AA799330jESTs, Highly similar to AF132951 1 CGI-17 protein [ H.sapiens ]2282314U20194a,dRattus norvegicus complement C8 beta (C8b) mRNA, partial cds144591326AI137930b,nESTs83391344AI145761GeneralESTs, Weakly similar to T21659hypothetical protein F32D8.4 -Caenorhabditis elegans [ C.elegans ]92921181AI072485GeneralESTs89991149AI070839ddESTs140511756AI232489ddESTs, Weakly similar to PIR1 [ H.sapiens ]250642247S45392f,o253702104L16995e,General228021602AI179291ddESTs3568403AA899821bbESTs11150207AA852004General,xGlutamate metabolism,Glutamine synthetaseGlutamine synthetase (glutamateNitrogen metabolism(glutamate-ammoniaammonia ligase)ligase)21611514AI176592c,m,GeneralESTs210681485AI175675zESTs, Highly similar to RAS-RELATEDPROTEIN RAB-24 [ M.musculus ]2467689AA964789pESTs20850407AA899956n,yESTs1131428AA799656tESTs, Moderately similar to imogen 44 [ M.musculus ]328281AA818113yESTs, Weakly similar to T13747hypothetical protein EG:22E5.9 - fruit fly [ D.melanogaster ]22903322AA892250iAminoacyl-tRNA bio-HHs:lysyl-tRNA synthetaseESTs, Highly similar to similar to lysylsynthesis, Lysine bio-tRNA synthetase [ H.sapiens ]synthesis22283557AA945172j,GeneralESTs, Highly similar to leucineaminopeptidase [ H.sapiens ]232291808AI234038GeneralESTs177681281AI105196q,GeneralESTs222111265AI102479GeneralESTs, Highly similar to translation initiationfactor eIF6 [ M.musculus ]59021087AI045871bbESTs, Moderately similar to inhibitor ofMyoD family-a [ M.musculus ]38031405AI170773dRattus norvegicus 250 kDa estrous-specific protein mRNA, partial cds17236227AA858903qTissue inhibitor ofTissue inhibitor of metalloproteinase 3metalloproteinase 32350680AA964368f,GeneralESTs, Highly similar to TGT_HUMANQUEUINE TRNA-RIBOSYLTRANSFERASE [ H.sapiens ]79131048AI043849General,tESTs, Weakly similar to ELL MOUSERNA POLYMERASE II ELONGATION FACTOR ELL [ M.musculus ]22308398AA899535zESTs2922703AA996816pESTs173792208M62388vubiquitin conjugatingubiquitin conjugating enzymeenzyme177292437X52619ccribosomal protein L28ribosomal protein L284234781AB016536g,l,tAlanine and aspartateargininosuccinate lyase,heterogeneous nuclear ribonucleoproteinmetabolism, Arginine andheterogeneous nuclearA/Bproline metabolism, Urearibonucleoprotein A/Bcycle and metabolismof amino groups15231960D26439GeneralCD1D antigenCD1D antigen228551855AI236150GeneralESTs, Highly similar to JC7301 Downsyndrome critical region protein 5 alpha [ H.sapiens ]1809599AA946503b,GeneralRat mRNA for alpha-2u globulin-relatedprotein236561058AI044533Generalcalpain 10calpain 854641055AI044345GeneralESTs218221648AI228642a,GeneralESTs, Highly similar to seventransmembrane domain protein [ H.sapiens ]15612533Z50052b,wComplement component 4Complement component 4 binding protein,binding protein, betabeta17589357AA892851vESTs248012187M35270a,tAlanine and aspartateAlanine-glyoxylate amino-Alanine-glyoxylate aminotransferasemetabolism, Glycine,transferase (Serine-(Serine-pyruvate aminotransferase)serine and threoninepyruvate aminotransferase)metabolism21707249AA859722mESTs162142194M57276iLeukocyte antigenLeukocyte antigen (Ox-44)(Ox-44)140131732AI231992GeneralEST11842214AA858617vESTs169431852AI236097r,GeneralESTs, Highly similar to E25B protein [ M.musculus ]131621455AI172269GeneralESTs16457546AA944856iO-linked N-acetylglu-O-linked N-acetylglucosamine (GlcNAc)cosamine (GlcNAc)transferasetransferase224871223AI102578mESTs, Highly similar to I49523 Mouseprimary response gene B94 mRNA, 3′endmouse [ M.musculus ]1836827AA799645fFXYD domain-containingFXYD domain-containing ion transportion transport regulatorregulator 111425212AA799457hESTs, Weakly similar to T32564hypothetical protein ZK185.2 -Caenorhabditis elegans [ C.elegans ]8438362AA892986g,q,GeneralESTs20915787AF001898k,o,w,xArginine and prolinealdehyde dehydrogenasealdehyde dehydrogenase family 1,metabolism, Ascorbatefamily 1, subfamily A1subfamily A1and aldarate metabolism,Bile acid biosynthesis,Butanoate metabolism,Fatty acid metabolism,Glycerolipid metabolism,Histidine metabolism,Lysine degradation,Propanoate metabolism,Pyruvate metabolism,Tryptophan metabolism,Valine, leucine andisoleucine degradation,beta-Alanine metabolism204212106L19699iRat GTP-binding protein (ral B) mRNA, complete cds150522183M34043bb,ccthymosin beta-4thymosin beta-425011296AI112343jESTs10636945AI011634e,j,bbESTs, Weakly similar to I(3)S12 protein [ D.melanogaster ]323380AA818105GeneralESTs, Moderately similar to Unknown gene product [ H.sapiens ]34311515AI176595a,o,qCathepsin LCathepsin L168851280AI105188uArginine and prolinealdehyde dehydrogenasealdehyde dehydrogenase family 9,metabolism, Ascorbatefamily 9, subfamily A1subfamily A1and aldarate metabolism,Bile acid biosynthesis,Butanoate metabolism,Fatty acid metabolism,Glycerolipid metabolism,Histidine metabolism,Lysine degradation,Propanoate metabolism,Pyruvate metabolism,Tryptophan metabolism,Valine, leucine andisoleucine degradation,beta-Alanine metabolism192301116AI059604GeneralESTs15313275AA875126GeneralESTs89441146AI070597kESTs, Highly similar to CGI-97 protein [ H.sapiens ]16416273AA875098o,r,General,uESTs, Highly similar to ARF3_HUMANADP-RIBOSYLATION FACTOR [ R.norvegicus ]207072380U88036f,h,l,m,w,xRattus norvegicus brain digoxin carrierprotein mRNA, complete cds250411942D14014q247712216M77479ccSolute carrier family 10Solute carrier family 10 (sodium/bile acid(sodium/bile acid cotran-cotransporter family), member 1sporter family), member 1139452300U09793aaepo, iI2, iI3, iI6,Kirsten rat sarcoma viralKirsten rat sarcoma viral oncogeneinsulin, interact6-1,oncogene homologue 2homologue 2 (active)ngf, pdgf, tpo(active)16366360AA892888p,qEST246482215M74054GeneralAngiotensin II receptor,Angiotensin II receptor, type 1 (AT1A)type 1 (AT1A)15961956AI012130bESTs19191164AA849525iCalmodulin 1 (phosphory-Calmodulin 1 (phosphorylase kinase,lase kinase, delta)delta)1642048AA800191aESTs98422385U94856d,k,p,qparaoxonase 1paraoxonase 185201125AI060052GeneralESTs22350529AA944014rESTs17644442AA924036l,General,bbESTs21502920AI010483eESTs, Highly similar to nucleic acidbinding protein [ H.sapiens ]133821205AI101527GeneralESTs, Highly similar to SR19_HUMANSIGNAL RECOGNITION PARTICLE 19KD PROTEIN [ H.sapiens ]78591042AI043660GeneralESTs22582559AA945442c,hGlucokinase regulatoryGlucokinase regulatory proteinprotein180269AA817841ccESTs16883AI009426Generaltissue-type transglut-tissue-type transglutaminaseaminase20571224AI102579d,Generalcyclic AMP phospho-cyclic AMP phosphoprotein, 19kDprotein, 19kD212091433AI171772m,yESTs23775633AA956483aMyelin protein zeroMyelin protein zero (Charcot-Marie-Tooth neuropathy 1B)(Charcot-Marie-Tooth14970298AA891738esulfite oxidasesulfite oxidase125161613AI179651yESTs, Moderately similar toSM32_HUMAN UBIQUITIN-LIKEPROTEIN SMT3B [ H.sapiens ]11701548AI177161q,rNF-E2-related factor 2NF-E2-related factor 23773742AA998356b,m,n,vESTs, Weakly similar to BCL3_HUMAN B-CELL LYMPHOMA 3-ENCODED PROTEIN [ H.sapiens ]5020458AA924768yESTs, Weakly similar to MRJ [ M.musculus ]81191620AI179974iESTs, Weakly similar to T12542hypothetical protein DKFZp434L194.1 [ H.sapiens ]19186190AA851226gRattus norvegicus brain-enriched WD-repeat protein (Bwd) mRNA, complete cds134671330AI138034aaUDP-glucose:ceramideUDP-glucose:ceramideglycosyltransferaseglycosyltransferase8317320AA892234uGlutathione metabolismHHs:microsomal gluta-ESTs, Moderately similar to microsomalthione S-transferase 3glutathione S-transferase 3 [ H.sapiens ]115161260AI103962aaESTs176621255AI103774bbRattus norvegicus dynein light chain-2 (DIc2) mRNA, complete cds74161692AI230458tESTs, Highly similar to 1702360A KDEL receptor [ H.sapiens ]12628737AA998123GeneralESTs, Moderately similar to HYA22 [ H.sapiens ]7142302U10279lRattus norvegicus Sprague-Dawleysodium-dependent nucleoside transporter(rCNT1) mRNA, complete cds113032415X12752GeneralCAAT/enhancer-bindingCAAT/enhancer-binding protein, DNA-protein, DNA-bindingbinding proteinprotein13574340AA892557GeneralESTs410873AI008974General,yR.norvegicus mRNA encoding 45kDaprotein which binds to heymann nephritisantigen gp3303302731AA997905g,tESTs19358894AI009675zEST164502241M95591e,GeneralSterol biosynthesis,farnesyl diphosphatefarnesyl diphosphate farnesyl transferaseTerpenoid biosynthesisfarnesyl transferase 1113952225AA858886GeneralESTs, Weakly similar to T33225hypothetical protein W02G9.1 -Caenorhabditis elegans [ C.elegans ]257682511X94769h103781777AI233300GeneralESTs, Moderately similar toCOMPLEMENT C5 PRECURSOR [ M.musculus ]117241232AI02812l,pESTs72661295AI112237hESTs, Moderately similar to NADH-ubiquinone oxidoreductase AGGG subunit [ H.sapiens ]22883441AA924028fESTs14482422X15030kRat CoxVa mRNA for mitochondrialcytochrome c oxidase subunit Va207032088K03241f,g,p,q,ddFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily I (aromaticTryptophan metabolismfamily I (aromaticcompound-inducible), member A2 (Q42,compound-inducible),form d)member A2 (Q42, form d)124631765AI232706Generaltranslin-associatedtranslin-associated factor Xfactor X2337677AA964307zperoxisomal biogenesisperoxisomal biogenesis factor 3factor 3175161519AI176621kCitrate cycle (TCA cycle),iron-responsive element-iron-responsive element-binding proteinGlyoxylate and dicarboxy-binding proteinlate metabolism, Reductivecarboxylate cycle (CO2fixation)61891572AI178027m,uESTs, Weakly similar to GLUTATHIONE STRANSFERASE P [ R.norvegicus ]23502734AA998025GeneralESTs, Weakly similar to A60716somatotropin intron-related proteinRDE.25 - rat [ R.norvegicus ]69411064AI044892ccESTs, Highly similar to TYROSINE-PROTEIN KINASE FLK [ R.norvegicus ]54601535AI176944d,GeneralESTs16782244M96674General,wGlucagon receptorGlucagon receptor254474AA817968GeneralESTs, Weakly similar to alkalinephosphodiesterase [ R.norvegicus ]931329AA799681hESTs7436141AA848354GeneralESTs, Weakly similar to T29201hypothetical protein T03F1.1 -Caenorhabditis elegans [ C.elegans ]205241078AI045201bESTs2388952AI011806f,GeneralESTs, Moderately similar to putative Rab5interacting protein {clone L1-57 [ H.sapiens ]19555506AA926120lEST239681454AI172260bbESTs, Weakly similar to similar to yeast SSU72 [ H.sapiens ]208692177M32062uRat Fc-gamma receptor mRNA, complete cds174802328U31598uR.norvegicus mRNA for RT1.Ma23577613AA955513yESTs23035576AA945712i,GeneralESTs12082782AB016800General7-dehydrocholesterol7-dehydrocholesterol reductasereductase6252126AA819381nESTs209312311U17697eFatty acid metabolism,Cytochrom P450 LanosterolCytochrom P450 Lanosterol 14 alpha-demethylaseTryptophan metabolism14 alpha-demethylase83842178M32167gvascular endothelialvascular endothelial growth factorgrowth factor88371233AI102849n,GeneralESTs600077AA818088xEST238252337U38180rsolute carrier family 19solute carrier family 19 (sodium/(sodium/hydrogenhydgogen exchanger), member 1exchanger), member 140902257S63233tGlycolysis/HHs:phosphoglycerateR.norvegicus phosphoglycerate mutase BGluconeogenesismutase 1 (brain)isozyme (PGAM) mRNA, complete cds231831331AI144586o,Generalevectin-1evectin-117469338AA892549dESTs200901904AI639353General,v,xpleiotropic regulator 1pleiotropic regulator 1210122038J02592hGlutathione metabolismGlutathione-S-transferase,Glutathione-S-transferase, mu type 2mu type 2 (Yb2)(Yb2)113721329AI137995pESTs75821021AI029996eESTs8512366U72497cfatty acid amidefatty acid amide hydrolasehydrolase200821906AI639488iEST, Highly similar to A42772 mdm2protein - rat [ R.norvegicus ]17938914AI010332tESTs25551922D00913m,uIntercellular adhesionIntercellular adhesion molecule 1molecule 117540620AA955914cEST, EST, Moderately similar to FBRLMOUSE FIBRILLARIN[ M.musculus ], ESTs, Highly similar toFBRL MOUSE FIBRILLARIN[ M.musculus ]237761129AI060224l,GeneralESTs154091918D00569k,oRattus norvegicus mRNA for 2,4-dienoyl-CoA reductase precursor, complete cds167671948D16478k,n,oRat mRNA for mitochondrial long-chainenoyl-CoA hydratase/3-hydroxyacyl-CoAdehydrogenase alpha-subunit ofmitochondrial trifunctional protein,complete cds75521085AI045802General,yESTs, Highly similar to PHLD MOUSEPHOSPHATIDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE D 1PRECURSOR [ M.musculus ]19143601AA946531g,tESTs160241751AI232374aaHistone H1-0Histone H1-0642206M60655g,General,zAdrenergic, alpha 1B-,Adrenergic, alpha 1B-, receptorreceptor14595318AA892128k,oESTs241081701AI230728GeneralESTs, Highly similar to S42114 smallnuclear ribonucleoprotein U1A - mouse [ M.musculus ]8872188AA851050f,l,r,General,xESTs21798509AA926365l,x,aa,ccESTs, Moderately similar to AF151827 1CGI-69 protein [ H.sapiens ]17931939D13912f,g,h,o,x,ccCytochrome P450, sub-Cytochrome P450, subfamily IIIA,family IIIA, polypeptidepolypeptide 33133531478AI175508GeneralESTs9905301AA891774o,wESTs205542049J02844kcarnitine octanoyltrans-carnitine octanoyltransferaseferase132822086K03041GeneralArginine and prolineOrnithine carbamoyl-Ornithine carbamoyltransferasemetabolism, Urea cycletransferaseand metabolism of aminogroups210152399X04229a,h,t,x,ccGlutathione metabolismGlutathione-S-transferase,Glutathione-S-transferase, mu type 2mu type 2 (Yb2)(Yb2)193021099AI058968bbEST, Moderately similar to CPT2 RATCARNITINE O-PALMITOYLTRANSFERASE II,MITOCHONDRIAL PRECURSOR[ R.norvegicus ]154871503AI176351vtripeptidylpeptidase IItripeptidylpeptidase II75861022AI030024dESTs197691221AI102570b,mEST, Weakly similar to A607 16somatotropin intron-related proteinRDE.25 - rat [ R.norvegicus ]1791955D17809pSphingoglycolipidbeta-4N-acetylgala-beta-4N-acetylgalactosaminyltransferasemetabolismctosaminyltransferase19191324AI137856g,GeneralP450 (cytochrome)P450 (cytochrome) oxidoreductaseoxidoreductase223101214AI102194GeneralEST90151820AI234810lESTs91351977D45247c,hProteasomeproteasome beta typeESTs, Highiy similar to PRCE RATsubunit 5PROTEASOME EPSILON CHAIN PRECURSOR [ R.norvegicus ]106591238AI103059mESTs133641392AI170606vESTs, Weakly similar to DRNG RATDEOXYRIBONUCLEASE GAMMAPRECURSOR [ R.norvegicus ]3925186AA851017jESTs, Highly similar to molybdopterin-synthase large subunit [ M.musculus ]207091447AI172064ibeta-galactoside-bindingbeta-galactoside-binding lectinlectin118281386AI170418tESTs95982031H33832k,v,aa258052007E01050t24841273AI104675eESTs4229590AA946057GeneralRAB7, member RASRAB7, member RAS oncogene familyoncogene family108872534Z83757o,GeneralGrowth hormone receptorGrowth hormone receptor19682224M83745yProtein convertase sub-Protein convertase subtilisin/kexin, type Itilisin/kexin, type I102001111AI059444fESTs43831542AI177056d,GeneralESTs155351928D10755GeneralProteasomeproteasome (prosome,proteasome (prosome, macropain)macropain) subunit,subunit, alpha type 6alpha type 6255002258S63458o144251568AI177755b,vESTs190171AA817849GeneralESTs21803857AI008284zGuanine nucleotide-Guanine nucleotide-binding protein beta 1binding protein beta 1121572080K01721f,g,o,x,cc,ddFatty acid metabolism,cytochrome P450, 2b19cytochrome P450, 2b19Tryptophan metabolism6018117AA819140mNitrogen metabolismcarbonic anhydrase 3carbonic anhydrase 321353175AA850247b,j,n,GeneralESTs206982502X86561b,w22079554AA945094bbcomplement factor Icomplement factor I2107314AA892006aaESTs23030457AA924763eESTs12313558AA945418rcytochrome P450, 8b1,cytochrome P450, 8b1, sterol 12 alpha-sterol 12 alpha-hydrolasehydrolase90961357AI169127bbhypothetical proteinhypothetical protein LOC56728LOC5672817766196AA851299General,xESTs69751499AI176229zESTs22336382AA893924vESTs, Highly similar to AF132599 1RANTES factor of late activated Tlymphocytes-1 [ H.sapiens ]171302209M62992i,ddnuclear pore glycoproteinnuclear pore glycoprotein 626215926776AB012933e,zRattus norvegicus mRNA for acyl-CoA synthetase 5, complete cds185251523AI176792p,rESTs203801946D16102GeneralGlycerolipid metabolismATP-stimulated gluco-ATP-stimulated glucocorticoid-receptorcorticoid-receptortranslocaton promotertranslocaton promoter237101695AI230614tATPase Na+/K+ATPase Na+/K+ transporting beta 1transporting beta 1polypeptidepolypeptide187271941D13978g,tAlanine and aspartateargininosuccinate lyaseargininosuccinate lyasemetabolism, Arginine andproline metabolism,Urea cycle and metabolismof amino groups156951932D10891xGlutamate receptor,Glutamate receptor, metabotropic 5metabotropic 519258421AA900613nESTs151901220AI102562b,gRat metallothionein-i (mt-1) mma9601923D10026General,yGlutathione metabolismglutathione S-transfer-glutathione S-transferase, theta 2ase, theta 24122388V01216bRat messenger encoding alpha-1-acidglycoprotein34331027AI030339GeneralESTs190121446AI172056nESTs21192897AI009732qESTs103961138AI070294GeneralESTs256862434X51536w2084739AA998151General,ccESTs, Highly similar to hypothetical protein [ H.sapiens ]23783345AA892773GeneralESTs24233687AA964756j,GeneralESTs, Weakly similar to CALMODULIN [ R.norvegicus ]217651787AI233696i,wESTs71221318AI137468bESTs, Weakly similar to GPV RATPLATELET GLYCOPROTEIN V PRECURSOR [ R.norvegicus ]61641391AI170597GeneralESTs, Highly similar to ORF3, splicevariant b [ H.sapiens ]197122312U18374Generalfarnesoid X activatedfarnesoid X activated receptorreceptor22992704AA996880x,zESTs102811122AI059947GeneralEST18886526AA943785GeneralESTs, Highly similar to AF157028 1protein phosphatase methylesterase-1 [ H.sapiens ]6801913AI010316iESTs213911003AI013902GeneralESTs, Weakly similar to ANX4 RAT ANNEXIN IV [ R.norvegicus ]64772035J00735tFibrinogen, gammaFibrinogen, gamma polypeptidepolypeptide80531470AI175033bESTs180382339U39943General,uRattus norvegicus cytochrome P450pseudogene (CYP2J3P1) mRNA190531934D12770o,usolute carrier familyRattus norvegicus mRNA for25 (mitochondrialmitochondrial adenine nucleotideadenine nucleotidetranslocatortranslocator) member 4170661998D89070dProstaglandin andcarbonyl reductasecarbonyl reductaseleukotriene metabolism172922212M67465fAndrogen and estrogenHydroxy-delta-5-steroidHydroxy-delta-5-steroid dehydrogenase, 3metabolism, C21-Steroiddehydrogenase, 3 beta-beta- and steroid delta-isomerasehormone metabolismand steroid delta-isomerase12276336AA892541GeneralESTs6071344AA892675f,g,GeneralESTs, Weakly similar to T20360hypothetical protein D2030.9b -Caenorhabditis elegans [ C.elegans ]1722170M27886rFructose and mannose6-Phosphofructo-2-kinase/6-Phosphofructo-2-kinaselfruclmetabolismfructose-2,6-bisphos-bisphosphatase 1 (liver and muscle)phatase 1 (liver andmuscle)116931351AI68953lRattus norvegicus mRNA for Sulfotransferase K2230321516AI176596lESTs7942363U68168uTryptophan metabolismHHs:kynureninase (L-Rattus norvegicus L-kynurenin hydrolase mRNA, complete cdskynurenine hydrolase)22634577AA945722GeneralESTs3121855AI008160h,uESTs, Moderately similar to AF151841 1CGI-83 protein [ H.sapiens ]25052146M16235c,e,uGlycerolipid metabolismLipase, hepaticLipase, hepatic155421239AI103095dRattus norvegicus brain Na++/Ca++exchanger-associated protein mRNA, complete cds6501896AI009724GeneralESTs22503544AA944823GeneralESTs23521143AA848407cESTs35041272AI104659m,vB-cell CLL/lymphoma 10B-cell CLL/lymphoma 10250522108L22190b,w1738025AA799612tubiquitin conjugatingubiquitin conjugating enzymeenzyme16531797AI233806GeneralPeptidylglycine alpha-Peptidylglycine alpha-amidatingamidating monooxygenasemonooxygenase199921407AI170777Generalmitochondrial aconitasemitochondrial aconitase (nuclear aco2(nuclear aco2 gene)gene)18939580AA945875xESTs, Weakly similar to S12207hypothetical protein [ M.musculus ]12677848AI007889cESTs, Weakly similar to SNXC_MOUSESORTING NEXIN 12 (SDP8 PROTEIN) [ M.musculus ]112351614AI17909aaESTs, Weakly similar to similar toC.elegans hypothetical proteinCET01H8.1, CEC05C12.3, CEF54D1.5.similar to trp and trp-like proteins[ H.sapiens ]207552483X70871rCyclin G1Cyclin G12190672AA964004kresiniferatoxin-binding,resiniferatoxin-binding, phosphotriesterasephosphotriesterase-related proteinrelated protein85211126AI060064nESTs15402166M25073Generalkidney aminopeptidase Mkidney aminopeptidase M202332461X59290beph and elk-relatedeph and elk-related kinasekinase18714985AI013194yeukaryotic initiationeukaryotic initiation factor 5 (eIF-5)factor 5 (eIF-5)66861496AI176130GeneralESTs15154335AA892532eR.norvegicus (Wistar) CaBP1 mRNA15933281AA875253vADP-ribosylation factor-ADP-ribosylation factor-like 1like 1209451411AI171085tRibosomal protein L39Ribosomal protein L391922500X83867pFatty acid metabolism,Cytochrome P450 1b1Cytochrome P450 1b1Tryptophan metabolism22586561AA945454gRattus norvegicus prohepcidin (Hepc) mRNA, complete cds13684105AA818770dRattus norvegicus serine protease gene, complete cds21757841AI007656tESTs1347157AA849038fribosomal protein L31ribosomal protein L316329121AA819259aESTs, Moderately similar to APC2MOUSE APOLIPOPROTEIN C-II PRECURSOR [ M.musculus ]258142203M59460GeneralStarch and sucroseliver glycogen phos-liver glycogen phosphorylasemetabolismphorylase59201360AI169163GeneralESTs227651501AI176265mESTs221962315U21719General,yESTs36061495AI176077aaESTs67881649AI228646vESTs145281890AI237718GeneralESTs170271398AI170679bbESTs, Highly similar to UDP1_HUMANUTP-GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE 1 [ H.sapiens ]256432375U77829j246902076J05571vMethionine metabolism,HMm:methionine adeno-Rat S-adenosylmethionine synthetaseSelenoamino acidsyltransferase II,mRNAmetabolismalpha58871599AI179099k,zESTs, Moderately similar to Vanin-1 [ M.musculus ]166101961D28557a,General,vmuscle Y-box protein YB2muscle Y-box protein YB2211560AA945453Generalsolute carrier family 28solute carrier family 28 (sodium-coupled(sodium-coupled nucleosidenucleoside transporter), member 2transporter)151892129M11794b,g3371738AA998124bbESTs7182916AI010450GeneralESTs23451474AA925243yESTs3427321AA892246qESTs, Weakly similar to Ste20-like kinase [ M.musculus ]16945485AA925541zheterogeneous nuclearheterogeneous nuclear ribonucleoproteinribonucleoprotein LL532310U16253fcorticotropin-releasingcorticotropin-releasing factor receptor subtype 2factor receptor subtype 2236821826AI234973q,GeneralRattus norvegicus protein phosphatase 2AB regulatory subunit delta isoform mRNA, complete cds111372078K00750tCytochrome C, expressedCytochrome C, expressed in somaticin somatic tissuestissues75371018AI029829GeneralESTs22351579AA945867e,r,GeneralESTs118492508X93352wribosomal protein L10aribosomal protein L10a229301162AI071578d,mESTs, Moderately similar to NEURONAL PROTEIN 3.1 [ M.musculus ]16178803AF035387rOxidative phosphorylation,ATPase, H+ trans-ATPase, H+ transporting, lysosomalType III rotein secretionporting, lysosomal(vacuolar proton pump), subunit 1system(vacuolar proton pump),subun12792372U75916GeneralRattus norvegicus zonula occludens 2protein (ZO-2) mRNA, partial cds3842817AF061242bbfracture callus 1fracture callus 122491394AA899289zESTs, Moderately similar to KIAA1049 protein [ H.sapiens ]82102256S61960General,yferritin light chain 1ferritin light chain 114602269S76054GeneralESTs, Highly similar to K2C8 RATKERATIN, TYPE II CYTOSKELETAL 8 [ R.norvegicus ]144241142AI070421iESTs257772519Y08355goxidative stress inducedoxidative stress induced23261469AA925145eESTs, Moderately similar to BHMT RATBETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE [ R.norvegicus ]232301854AI236146aaESTs196171043AI043664aEST17473903AI009806GeneralRattus norvegicus protein inhibitor ofneuronal nitric oxide synthase (PIN) mRNA, complete cds11050626AA956164GeneralESTs, Weakly similar to TCPA RAT T-COMPLEX PROTEIN 1, ALPHASUBUNIT [ R.norvegicus ]18315822AF072411cCD36 antigen (collagenCD36 antigen (collagen type I receptor,type I receptor,thrombospondin receptor)thrombospondin receptor)23189497AA925844nESTs2653678AA964319GeneralESTs250692279S82820f,General,cc28181601AI179144GeneralESTs146701480AI175528GeneralRAN, member RAS oncogeneRAN, member RAS oncogene familyfamily207142141M14972k,oFatty acid metabolism,Cytochrome P450, sub-Cytochrome P450, subfamily IVB,Tryptophan metabolismfamily IVB, polypeptidepolypeptide 1114591355AA892847GeneralSphingoglycolipidHHs:N-acetylgala-ESTs, Moderately similar to alpha-N-metabolismctosaminidase, alpha-acetylgalactosaminidase [ M.musculus ]8515170AA849917GeneralESTs6862167AA849729nESTs, Weakly similar to T28096hypothetical protein ZK909.3 -Caenorhabditis elegans [ C.elegans ]90121150AI070879rEST13575340AA892557aESTs241811244AI103320GeneralESTs, Moderately similar to T26785hypothetical protein Y40B1B.7 -Caenorhabditis elegans [ C.elegans ]28381143AI070511dAminoacyl-tRNA biosyn-HHs:valyl-tRNAESTs, Highly similar to G7A [ M.musculus ]thesis, Valine, leucinesynthetase 2and isoleucine biosyn-thesis21328171AA850130jESTs, Weakly similar to NB8M_HUMANNADH-UBIQUINONE OXIDOREDUCTASE B18 SUBUNIT244332147M16407GeneralCholinergic receptor,Cholinergic receptor, muscarinic 3muscarinic 3175531253AI103643GeneralESTs220111498AI176212GeneralESTs, Weakly similar to T25165hypothetical protein T23D8.3 -Caenorhabditis elegans [ C.elegans ]185711868AI236612jESTs, Weakly similar to T08433 helicasehomolog hlc - fruit fly [ D.melanogaster ]21401456AI172272General,zESTs, Moderately similar to A53004transcription elongation factor S-II - rat [ R.norvegicus ]16680696AA965190n,yESTs171752457X58389h,wR.norvegicus ASI mRNA for mammalianequivalent of bacterial large ribosomal subunit protein L22187952386U95001bRattus norvegicus diphosphoinositolpolyphosphate phosphohydolase type II(Nudt4) mRNA, complete cds2702647AA957307GeneralAminoacyl-tRNA biosyn-HHs:seryl-tRNA synthetaseESTs, Moderately similar to SYS_HUMANthesis, Glycine, serineSERYL-TRNA SYNTHETASE [ H.sapiens ]and threonine metabolism8752353U60416bbMyosin ot the dilute-Myosin of the dilute-myosin-V familymyosin-V family184951899AI639042vESTs150421606AI179422cESTs126141474AI175294jESTs, Weakly similar to GROWTHFACTOR RECEPTOR-BOUND PROTEIN 2 [ R.norvegicus ]130951468AI172595nESTs132031651AI228728rESTs3411746AA998638GeneralESTs171582390V01227ialpha-tubulinalpha-tubulin25108137AA848268j43551248AI103410tESTs TABLE 2U.S. Document No. 17,409,56.1Model CodeCompoundaAcyclovirbAcyclovircANITdAcetaminopheneAcetaminophenfAY-25329gAY-25329hBicalutamideiCarbon TetrachloridejCarbon TetrachloridekClofibratelCyproterone AcetatemDiclofenacnDiclofenacoDiflunisalpDioxinqDioxinrEstradiolGeneralGeneraltHydrazineuIndomethacinvIndomethacinwLipopolysaccharidexPhenobarbitalyTacrinezValproateaaValproatebbWY-14643ccZileutonddZileuton TABLE 3AACYCLOVIRTimepoints (hrs): 24, 168Non-Non-Dis-GLGCGenBankGroupGroupGroupGroupcriminantIDAccMeanSDMeanSDScore1069X1509623452511100520958983L106523764623652963393AA9982091782586101949423S6186811892055992259523578AA95504236656227679418705M3069116325104269525078U3354050283302869426330AI235911206344793945573AI059063117081461483418249816538AA7994491085123948864AI07031923942527497563Z5005123583349534439723260AI169617−501125429721013J028102169464185914829618356R47042115205625963918AA8013332711114959214AA9251164106423286947782AI23451538379162499819392X0291822631761035520964017AA81828728575339321657X613811279511546196973882AI01019111191156591949618417AI230166−16584901299424091AA9576121181647269620716M94548153818711836639425091X651901492288299422187AA94322918963408593919615711AF077354084426959422AI072888113225417979591AI178769−644479879321204AF09592726674309523709AI112173279721581449416458AA94495614111808432379420236AF0915702243214337946532AI23410519516137419412092AA848618116194930957684AI030242643110338142932047AA963366247181517193671U04808542619939162AI07239235368183619522978AA8599315812123379511066AI0716024526828679941854K028145990106813229539924825X0274114772136302889625679X150131272806362459818770AI23336246917375919419560AI030921617633001029811097AI07174919324107429515965AA866404−161431259424437M223571331070239923933AI23637619021128399315419AI01047682297529163936873AI01005536513724948232AI059122712223209420971AA79957637671219321010AA925306928816242889423637AA955587−1516741819423826U381802052614027959349AI01214322739426126931850K028147440120116011106994592J02646976149399416304AB00842413951431074555949469AI0730231092639389615141D902658351413996575X1573414103086662759511467AA90106927730131539724654AA819333128245425961371U27319170364743971818Y112834293562150110439610190AI0593426421022979795AI07198983832269612577AI111344108445115214298228U20194665753981119421822AI22864222122344919424801M3527056878368126953431AI17659513491067392889516420AA800191652654361069323775AA95648326944118489621015X04229241528520581470986329AA8192596595350486929209416610D285573813141579619617AI0436641231757329613575AA89255747131194393 TABLE 3BACYCLOVIRTimepoints (hrs): 6Non-Non-Dis-GLGCGenBankGroupGroupGroupGroupcriminantIDAccMeanSDMeanSDScore2515D175121144348316810020233X59290270−32271005616L0019125709389843110013332AA893080553210701003292D0075398366991665126010014425AI177755415215242737010020698X86561375947765931910015190AI1025628433274131114911002010U056758061658189714861004199M83143156810466022810020701AA875097276530063325810019011AI10261863616276831004066AI0137827031529211710021975AI172247557372356010011504AI171652292671923710019057AI2350941679413471001850K028148072747162011521005110AA9252746541228210010023424AI1800682447191120424410011904D8518326224694810022866AI23375472341322911006957AI010707840453399412V01216329018710797069921353AA850247591161380349991854K0281470318541336979997047AI171172−16145381089914676AI23461518968532996352AA99760023262−1427996171AA819633−268192128994892AI044292517661152529917340AI007803408337810764249914459AI137930120461339434920719912845AI170497−33760389926133AI009950102115816312499402AA9451432684204861434999795AI0719891241032269918795U950011052444151359919411AA893667121643249925317J0073531693711022561995622X0583428042761100486994833AI00917879819219914324AA850402190431922997053AI011467−1315774369915961AI0121301811242389915703AB0093722581613240998522AI0600714392813072991114AI0299171557211514182991561Z5005215971766522429924211AI11185312352961119916561AI13786237628206469922513M2356620251016−626019910988AA819640103823429923387AA9459522073030379921933AI0290571085753150941865991818Y112834538294151010539912734AI0112081941583339922018AI0083094628314463993589AA99859014027242399169AI045171238337031994998AA9246834911−10189919769AI10257019252047642659921980AA8934541043153403111996057AI172102473102101829915191AI176456752311938359579921740AI17681022732877342839926368H34047116115287995579AI17686338965131419920524AI0452012245917359915189M1179499041521114313069920088AA892666874163359924012AA95733516332143733159924200AI0123561653218380222998053AI1750331281166959911424AI010936247209862994198M8314316351227722529921917AA89122047913978479925052L221901925428117991809AA946503311125634349917844AA955927440311527699640S82229734−1140992310AI0299697312327886993773AA9983563444357469923368AA8006782038537993095AA997077−491411957997122AI13746810441304161189913932AI230988−202366953995675AI045026220711144992532AI176590−712011283996544AI102064−139126111299 TABLE 3CANITTimepoints (hrs): 24, 48Non-Non-Dis-GLGCGenBankGroupGroupGroupGroupcriminantIDAccMeanSDMeanSDScore25743X80130145207228967918AI1797501504659289620299D14564249385722229625137AB0055405091713966017AF0370727829613452968344AI05951111381944682699610886S49003357377343019617540AA95591411921805882329622667AA94506975206369618902AA8753902953718546963254D1075633627222569622927AA85992094213722959191AI07210720468711277959032AI179950907916031469515029AI1706966192231648491953665AI0093763568317271959866AJ0054244712−1279413645AI23269429583165539418315AF072411134355537942799AI013778107264652269415042AI1794223101373167941291AB00049120732129349422849D1075430027202529424582X16554772131209414353AA859585892046229418393AI2306321833011334944330AA8187478272291634439937697AI176942202674691389321471AA8513432747−5954939754AI11219425242221309317049AI1724171873933991934242AA89332517158427161938490AI05996210225248999316883AA997345125918420125069316205X06423777537712689324577X5515362546667263933265AA9977849324196749311422AA7998122761111939583AI07118550626550619322929AI071578591451346799931246M57507401488279322582AA94544218433375134931409AI01280220333348919215469AJ006340144198931922505M1623531551584206921903AI1773776023146519222387AI2307535358190224492347U01914721433209220123AI072214153463131099212551AI2300561233723979927516AI0721835824271189210544D6341123226164539214492AI03009132552215899220848X546174059722257925936AA964214561318249262E06822761112431929135D4524756332558160927403AI0292127961891509478928984L106522382916644924486AA892298511021169216984AI01316176984465207925046AI2378552478177439221683M65149772016279211635AA859645175212596292851U72497245263708692573AI23208734458678284929498AI073164791444199217837AA893641781346189217591AI1713542527012446916554AF097723309344891439117664AI234496706197263149919016AI070903130433827739959120169X0334761339339118239AI1799421596731309117524AI010568154335127167349115301M609211403012589110015AF0832692264313741914527AA89277475154318913404D3074020435125309112933AA9636823417−4239123521AA8484075621831691159111416AI1721851632111038912161AI1765921203479371278912013AA892390952732279112677AI0078892111−417914444AI1008821447460832091650X552861535045369121066D105871161368219122566AI1771221375445329112542AA997499189433951539116700AI0088385422176100911475L1676419380531109125480S467852271024971789114171AI17807313955573091 TABLE 3DACETAMINOPHENTimepoints (hrs): 24Non-Non-Dis-GLGCGenBankGroupGroupGroupGroupcriminantIDAccMeanSDMeanSDScore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−41164269711404AI237002782144210115985460AI17694413910333984730AA900326743615109579822930AI0715781112575356983916AI16994754612616264059811403AI1710888241081781769822929AI071578−3328134879798 TABLE 3EACETAMINOPHENTimepoints (hrs): 3, 6Non-Non-Dis-GLGCGenBankGroupGroupGroupGroupcriminantIDAccMeanSDMeanSDScore309AA866460318315271359617897AA89390516333386131931312M31788269274991539528D3166223053631259938899AI103957323426702329322705AA9460328116734932677AA96344318119043932505M16235332315872069210695AA8196797632246969525460M89945219588535159414191AA85892419866279518867D88250303496382429210636AI011634822822287924003D107576921166549411478AA92623177251795592135D8783912331268809421657X61381275485562069420931U17697116343571469421742AI1761724216157819421916AI013627257304451239322635AA964289763619948898AI103957335366132109312331AA946466106322951229315926AB012933215404751859319408X02610453357372329319335X053001502225868932484AI1046757137346196931430M84648−718996693811D6370430842536161932901AI043752401290299325370L169952426149709324170AI145601331311452926365AA89916312654399313670AI2277344612107379317533D006361212426394933934AI0115109212271914567939633AI007768241395489218978AI63920813217223589223261AA925145136427924527219217409AI17241719542340909214258AI22990233148234934199M83143348636682309316039AA7994521272320747937650AI230142381710371924879AA923852142211554921529M81687252434581119320146M22926951151249217468AA892545247344451079320895AI230549503217364926387AI2346644917102259323068AA926036161905351929223029AA94493527777244489218564AA8007451823132274947872M8691215527260559423031AA963661−9879659525204AF080507202284241229723030AA9247632240448303921973M601031613333587935597AI101622852717342923537AI101690184754611109419069AA943737170697153039322351AA9458671178220269315154AA89253224329488142967225AI0136571064831795937069AI01030112236278789415599X75253260235041529721502AI0104838237213669215995S7435131812179779323452AA925289743317546923131AA893032125303731309612946AI22829118436363919324161AA85858820723378969214970AA89173810125179349216450M95591712122672945952AA96310235913279739324321AI2323403471018542549211021AA819767723626796938387AI1763651213629266947582AI029996119414832039511726AA849518808365110130946135AA8190654616168659515996S814783228089819322352AI1759593671468981952536AI176616126396003389411727AA8495181153467145172922911AI03083535515011403529415997U02553438132102939510184H334262112125489720513X05684181012966945934AA81769585353831589525799E126251220196117925141AA92539313657795473934360H318136017236999516982M586347471312212539521842AI1722938226445218938344AI0595119224822719615069M89945159426903769524249AI009273119341369128094 TABLE 3FAY 25329Timepoints (hrs): 24Non-Non-Dis-GLGCGenBankGroupGroupGroupGroupcriminantIDAccMeanSDMeanSDScore15127A5693722291445242471005493S569363342061641005492D3806133436386410015126D837963088202886463996143AI10516715571208725329918989K0013636882191071818999134D45247548637885991876AI030175117065582186991354D3806590494218129991795L2420718641634273329915124J0261235003569935489920705E01184605456783810779920703K032412972408395536991462AI23558528217170479920707U880361649165474224991793D1391240094138676229918401AI104300119320807175992424AA96461715451108542009924860M135061209232318242991794X6440182941002152013559922953AA946509625121194114991797X62086543461412661027987246AI013331785−44679820704M2612751845831023969983816AI23372957520376999825056M1323436658607578339812156K00996331711924529659853U162532298119981796L2420710152172181279812155J007283106814542761988872AA8510501236271494236986735AI1724971473100399812447AA956769135653349821957AF0874371281164429812157K01721416812154981077988661AA818604943213649825928AI6392362003921986236AA8186272654311971438987926AI043913305958255982388AI0118062353691625379988864AI070319127653759813330AA997716139145042981792AF0042183534267769823321AA89282132712219539825069S828207261211671499817091U731741482753349818293X053411589359494789825281D308042452114934985824AI04555515097045988283AI0592902403110057981347AA8490381065138383389815879AI22831353574310849715125J05132346740211817659720872X5170777895671909716320AA859899534107319717256AA891739751374261369716345AI013250839335601349716703AI17930016602912073749715623AA84976943482249720842AA84972243918302689719501AA8506016050329721040AI011734914236972109721039J03190680189203125972569AA96512215402438752729720153K02817557104691399715850AI23679517902028573009710152AI059110521213219722884AI01075532743168529720864AF045464897188344214976071AA89267539141228659717292M67465878195722269724163AI16943048832298909715848AI0078202127293929381976072AI22863031602862015464979931S8327971537473124978527AA99646119891521909722052AA899498587223371379721053M1548115711971391955972615AI22931811941985997357U0483538380339717092AA8931891672586349717117AI228042157115410152089725064S453922030389842315973945AI232719446−2259718027AF039212105215937972350AA9643689551295851299717305X590512631128167012639717999U1948516132710995259717154M1588329323175499721038J031907552422451329718368AA7996454961036092973645AI23536226114172419716272X7645616461371307732971853X123673639291219619859710200AI059444742221199722883AA92402812515622897 TABLE 3GAY-25329Document Number 1740956.1Timepoints (hrs): 6Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore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−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ocument Number 1740956.1Timepoints (hrs): 24, 168Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore1794X644017428254414751241981793D13912355612038475719818717AA9450501561356634307951795L242071878801415294959135D4524780534555158943121AI00816012241797462429420707U8803613022714692179415126D8379620793568804649315125J05132288747111707579225216AF09156333963189215879AI22831342448310849215124J0261221852979885559212299AI17201715951198504019210626D14988300659212308139220308X563273476520929313AA79968122947139125574U0675241666169121623V0121717681451045437911682AA94355531754179118719X6341025294259805679117958M3417612760359119287AI23237941774239016762AF05953041669469020704M261271523197103210039025563S814971870301970372892970M147754173740167213518918728AI1707766810105268917175X58389583394671368925754X8969626550188919665AF02281923645158925608U53927123352189145AF0645414588320896985AI01086212852687335078917541M26125266140411397468916953E01534808676602288920427X53378819605771758924693J02720148022291943489634K01932219737911076008922582AA945442523533721348914252AA79945728552138920716M94548202215011766598921904M242395411848216619628915471AA85986934131270588922927AA85992011538228917427AA892314130592824345893406AI0450832725714363895907AI104261480343788688534M58041273745813208678818952AA92400642191837884441X6214685946627199885175AA818951101050568825525S7250518943159795118821015X04229463176520301445885667X5820079047593177887266AI1122375538336496887351D8303626748188817921AI176422441383461068820984D901091342938763958816922S456631024886402368820523AA89184225456528820810X141811205678183238818627AI23228411532198817105M29358895716932318821882M8374012341087613018816204X06423727475641648821663D50436574106374117884434AA68522128852148816947X0805616211798373928825479S4566314441778543318824646M23264562212889620X53377545504151188815106X575292334201127770088538X9424644872178810109X584651024517422538821012J02592265867210936638815875X6214513211057993648821772AI01117940462218810503D21215571374641118825768X94769901413134888212AI231807273530413989148823348AA874813511485238817577AA799566401482258818299AA7993697911110228825400M14776286439512891125888597AA8185936919109398820385X547939761176672018825675X14181702645641988823665AA85205531452138811665AI102585−8337−24228816726M862358229359219488635X788482330398113067488358U529481798278104556487 TABLE 3ICarbon TetrachlorideDocument Number 1240956.1Timepoints (hrs): 24, 48Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore14424AI07042129660652449915787AF0955768782914100669K030397587710020523AA8918421691855529915174U598091976718429918712AA81889479423151007893AI0437611083111873971008025AI05836587966363991004375AA89386911223315100515X638541401357201003909AI16990322757281999926AB003042220814524998119AI179974256−232210023171AI230190791464231019917119U257461381251249911376AI1128631754228209915213AA8009087832−1101004226AI1777521385712109922023AI2338221766817309917130M62992243419329993910AA8943451061943149920788AI23605312376489921128AA84855514082−4249916457AA94485640144153401002242AI01263531813723598661001045AB000280105457179915832S6858924122993210012306AA9448981464910845019917158V01227325816535995541AI111707363318−16149919275AI0094601432635291849915075AA8752691678317189914199AI234133499208119449920709AI17206424919510199918002AI043655228111222485810016346AA79982421023783010022903AA89225023517117279923889AA89252039753172419912581AI1452351362237199925581U133964416−479923035AA945712793158620210023312AA8919208772715998715AI069920283991535676994491AA818798682187143509919456AA997841157214009209920421L19699114214022992736AA8943301203323149916214M5727631611542219914656AI237820122342914995780AI177869182106−58401001061AF0093297034−379915920AI17893832110184439924598M2575832031171309923243AA8518032317917147929921696AA94432438252164449919191AA849525302351910283069917167AI01369059329602628613993895AA8940292387635239920082AI639488176514528994989AI1750873922503125996107D131223243794379914421AA94275132722144469916701AI00883845112122266949916006AF0625941482615239916007AF06259498151413994395H331491851687279917502M1215632562874099910S76511106211916993831Y126351684441229923678AF0870371165618139919319AA89193729523122409958U098701721854259916267AI103977484751885410015500AI22933792697423100995884AJ22318480238119925279D307404187316944991386L085052084485269911893AI230951513329−238993690AA9990062542291299912694AA9579062918261869916012X62875134312818995421AI101270827333197689920448X1705327916144219923538AI10272758949586899914258AI229902269278031994317AI07153186208119923781AI639012128321213997161AI233407142184627995175AA81895145315147469914840AI23769845714571349921765AI2336961782836239923275X974433042214641997414AI13758644059174769918387AI2377312509525209914929AI170353795322112499920651U36992150592128992855AI236707112419741886995733M81855315557359918386L032941774042229918385L0329427184282699 TABLE 3JCarbon TetrachlorideDocument Number 1740956.1Timepoints (hrs): 3, 6Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore1397AA8177871111034629919221AI1033749618−66291005926AI1776381315411810024019X7723516813322510022870AA926360732284225810023878AA79968668127309921326AI2300131111111201002250AI0123541125317906821002501AI11234343752100361008795AI17261818423181710014664AI232081436351284610022266AA94560119957164433710024179AA8930918410161110023157AI17248929435752910022283AA945172461243816210022612AA945624449309921001923AI1707548751092488110018777AI10278812325−323910023595AI23683418730352210022958AI1713745009576351007268AI013541242517741749922039U131761307502110012437H3368614912371810022631AA8490302273590822610021353AA85024714366138434010024225AA92549067183438810017407AI012145385149197955610010533AI058430653945716899606X7189815066−512110023435AI229502286802489914004AI2332612764777429925108AA8482682121112017998715AI06992014163153667510012542AA997499562039515210012343AI23143320020472310019069AA94373758197093061001600AA68647055416929871002897AA81803920432412110010110AI058863237189809921328AA850130127416101679915376AA87520637431170459924146AI169668375331755610018396AA799330223515025991813M1965114172−532010016576AA7995702741283318993674AA945587482450513010016579AA957143377206631003963AA923955351239411610018192AF00089976910111003925AA85101774317682961001599AA68647020152142510017339AA84949723187874081004954AA92444428731914310017721AA94576242123058910024233AA9647561254282723710022957AI104897148529425111310016618AI16896718227292210025643U77829302331252710013286AI03079057204561279910108AI0078571962472261008834AI14589914229432995200AI178699175542612993833AA85125583244031031008808AI07013242838512210018571AI23661211510−73210011431AI23612031848662910013694AI23053824317106351003062AA99885771618033229379920988AA900562243589062109910636AI0116342112221879911608AA85963392930169918002AI04365534811222238599923137AI0704081152264239849920708AB006461114144317998850AI235059322736730995780AI177869269169−58359911549AI232174500422005510016492AI07031577249302549913911AI23626212618291510023802AA9565354512252729913796AI22905610121128997161AI2334072604946239915427AI1789512111779309912792AI176883214383927994900AA9240246516383929916267AI1039775971051875010023678AF08703713135181310012999AI176276527101138419924388AI236772781387135629923538AI102727765127858910017580AI010145319201639917514AA92555410523486137998759AI2376464932165359912614AI1752941874736209919031AI070532112271414529913619AI1794643751317871999963AI04514430177022829917734AA998683862224638799 TABLE 3KCLOFIBRATEDocument Number 1740956.1Timepoints (hrs): 24, 72Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore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−1764229918958D139211064328274719917554D8510034332751151748999931S8327911211604701159918029M3875916679−8279912158L003208283132316319923884M73714926122391979915601AI16963154278267609917626S7855672158396839916546AA80012048376177599917549AA892776795234891169915409D0056916954364511749918957D005121062325308819920915AF0018981875547401254999268AI07237545615415058992190AA964004200179264995887AI179099947183811569926258AI1775011852858329915582AI232320180653513584930629912155J0072817114055457739917516AI176621523142223479915408D00569883232247102992457AA96475210081982181529922598AI13750649755105534699819X022842566199182914529914595AA89212854315673599917601X95577238109379921354AA8997213337700374343998944AI0705972213042559816721D30647539118234459815175AA9455833552521144983903AA8999867752−97589815391AI0100831404607212599821341AA85019519382428142879815124J02612238698994560981818Y112831723179151710669815126D8379624721938854679821355AI10509424216192952669815085AI23382938608961497399989842U948561328163116963798397Y09332217708134987274AI0137151963563389821848AA9578964343126554984940AI17878868413216794479813004AI2362845112332283986439AI05843655310321580987420AI0292911589124793315981448X150301513142727223982888AA92490250901014258871198 TABLE 3LCyproterone AcetateDocument Number 1740956.1Timepoints (hrs): 24, 120Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore12158L00320540792336329925055M11251544832436309912160AA8184122593403117615329912156K009969481694599829819256M155621691730692975074AI1016952420161879715127S5693791286528266964232AI0129583579652964172AA92551410541189614840AI23769826573459615391AI010083749487242649615383AA955358558123479621228AI0444046010140549616124AI1769636018189959617685AI1130551895933961957AI1721434521411540699967317AI1361233889032962125AI102519430173129966842AI0097642066335954234AB016536242234581759522914AA924335689591105278953993AA9255409117194639518829AA81879650911347956055M1233741642794300953997AA925771511213250955241AA9259861552931690953866AA89307455432139512155J00728849122549778951795L24207886169429341951394U370992541089520707U88036836117476234956479AI1696904477611164299724860M135067631383192469823032AI1765961753532078958036AI2308846121195749722917AI22812015122270649515987AA86643536445292910018669AA956453681519175953510AI17642371149219618906AA8925611652689289711960AA891740−223087339815755AB01311221434567179996431AA85908545101841969815500AI2293372392542710697906U83112871443159715032U89905171274021469519555AA92612082014514343269520804AI01168424416768003629817788AA89904523195249882609823776AI0602242213127649521078J0279132118539148971551X0615030025743310993381AA8929932161611831986801AI01031616826420127973143AI2324081803036093978872AA85105022072224861989917090U731741743168249911724AI102812266101499616319AA87504789173318971478U3231419229362899625183AF0501595811−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ocument Number 1740956.1Timepoints (hrs): 24Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore15003AI16932768190549915860AI1028682632159820707U8803676694802349720449X170531003637459819624AA998422−25157251982248AI1703321262127864993265AA99778450151967498899U35245−141350229823839AA95668411310254789824219L27843441103021119823321AA892821803222052986018AA81914076320559134088981173M18363304501173804984444AI10088243196073219924712E018843610−5209814081AI23316474743440133994267AA8594128984323381389725470M95791481131999891U66322−34652519818824AI2322553218−74419825480S46785158514961789713796AI22905637712119710249AI059711436−1526987053AI011467−272473379822511M22670320162−265996431AA85908511716911791849916879AI16928450045968243985962AA817875924613249812792AI176883106114029982536AI17661664315933409721977S46785169385602059820162X17163384−26529814600AA80107632497114629819249AA997342551250191739812551AI2300567615239799812450AI103955−71317280981266S806312213−17129819769AI1025701629487764266975848AI16899433422595132986033AI2330815143210182589821973AA944840871430012898475AI2338285975710212009710307AI103695142351444981641E0342821831114429723500AA86001070191920986016AA81816363521422577859713551AI1776021001052189817913H317071081518430971583U0720191203817989166AI1374061365827179822929AI071578−58171340802986387AI234664632101269821683M651491053116279822619AI0098256031032581059718354X5985912238243398945D8866611749−3237984026AI23383572223377136986532AI23410526539136419822765AI17626530411073639724366AA956246683167619813762AI23032612115356985197AI103376668103336909711720AI23227314572467622219822487AI102578196556237973504AI10465955611228590976189AI178027436244408523149816809X58828139253829985899AI17003830421312633189814996X160381202922399717496AA9261094122371719817340AI007803277672610784399820803U0925688624285985791AI045423−87282743971690AA8178293397314650974374AA89386948316129811762AI1786318723−930982555D0091330794124519811553AI2307652674087489810659AI103059651137153154983073AI2334942729880989583AI0711853071025375981221D11445438732591983773AA9983562324857479721707AA859722194454448972161AI17659216143633732809721209AI1717724191618586978215AI1716929243613841289716859AI236753550882261019822930AI07157813115723579819363AI1762472455419478809820354M143692896160549817664AI23449679384265151985934AA817695332337916097819X02284107224183614519713932AI230988−10125685497 TABLE 3NDICLOFENACDocument Number 1740956.1Timepoints (hrs): 3, 6Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore17787AI16975810807912341075976478X0586121352652343211097818X0229118671572583253797819X022841557112183514549612792AI176883911340299616274D102612075237311233329617564AA96367425219396899625400M1477610319213091136956352AA9976003312−14309616085AA8748894762123953845AI0114813879838952010U05675175924219151523961877X745932843754217495111U02506178617723232260956862AA84972914625287839523512AA95528237755776251956373AA8587263357025951684X563251721204212119369510534AI0708322020165979520650M12335114111212988249511080AA8513309914191579411576AI1461773198330948211AI23180712047616851315948521AI0600642377237941818Y112831292119152010679414390AI23238544983229515755AB01311232336567180943019AI2312184159761948549AI233639328767202249413757AI2286769721195549416767D16478304294761309413095AI17259532457169417906AA899762227223951369319258AA900613−515103969423189AA9258441312425975943044AA997701104514954934186AA945169181118926732390941876AI030175306475861889419038AA85181891914939936825AI045972224313951259424219L2784346649302110942367AF0957412172533774947667AI23368741986299418522AI145870222524361219422725AA900506−91246329314094AI23537772711735936640AI1015000146234943467AI2378355217130559310248L23148691032229420911AA899901319535611379417903AI23108315420236539420850AA899956−152074579416680AA965190116543631349316565U91847601022219318302U33500299541311049425325K0304584313912671228948989AI07079240118124934899AA924017722913499616327AA87505020343432126963310AA99794555271322946598M5858728731170639421353AA8502477451871382347946604AI229192694018936891U53922222234031069714459AI1379309574934433320669724321AI232340370858482599515786AI01392412436288879425852AI6389985692511977003AI03025912636364131966252AA819381155193631359725508S67620279−6169617676V012351521111233420609415180AI0103545111109031999419085AA892598160238937946438AA819269602418064958837AI1028499931222579515551AI2307592042432461967362AI0290263921118782389519012AI172056934211428152972242AI0126354544101123328569516465AA901042196233791029624366AA9562466015167609423608AI23319012893803921929726335AI236460328777111758639619086AA89259822034117499520161X546861093028379516821AA9990429101934761289713481AI23535221879299616312AA875032621816149615932U12402146199225944868AI17076312121280769717709U24489134284435955384AA891041146292742971221D11445361712490983773AA9983561694757479617664AI23449672010726315097 TABLE 3ODIFLUNISALDocument Number 1740956.1Timepoints (hrs): 24Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore15408D005696261124911210018687AI170568360117248243010020715X07259271616330833010014595AA8921283275756810020713M57718360931352937710022416AA944380438241321121003149AA894030120503710023699J02749166918651129610024798X0635780629442149100354L3259192074691001728D16479484202197810017758K03249213457930433410020711AA92426710582081251641001857AB0104281353522154998527AA99646129621521909916148J0275231325937523929915848AI00782022811009303829912093AA848628−1021229918125AI00878788017527153992457AA964752963382211589917764AI2346042068978013009923698J0274916333922973589920925U0897625293813303359918685AA9977462041413349918293X0534132003499454649919053D1277018035339918686D0072941827045154499916767D16478109997473127993431AI176595147218741289996919AI0104613131282246994271AA92560351268591459915409D0056914602134551919926109AA9970091617209150281994196AA89930424745791089920714M1497233358694153309922603AF04457459890231789916150AA79948915743955072379914267AI011738261314711193969915580M33648401114215859429925064S4539220881728433169923183AI1445865162721788995213AA92576762734981719916521AI01047047038231659915383AA9553582012122479918958D139215895827793992811AI1710903331217856998856AI07240296347169916768D164789271613921079918742AI10513111591553521899925070S83279865113404105995602AI2326111266120215232999929AI01383411571545131389922604AA94557832126109864359912157K01721147235050910999915577AA92455731144018356639915850AI2367951835108858301991793D1391218691128756489921354AA89972124633813853939920915AF00189813732784062739914763AA94448117771105063799921341AA8501951507728182969910887Z8375765111028999931S8327991281472123981858Y0933324390261879821750AI00966340155135609820555U260338862172951539825500S6345878415437984272AI2313093274939889815085AI233829331739715054289824665AI009098519174769822083AA85058797812389821010AA92530614951166232859816703AI179300232317712063709819852AA9460535414120986409AA858910193510546981977J05470697633001139817847AI1782141109687291419818891AA924598569652731669816546AA80012034420178639816518AI17654613531825441959814070AI2326491801167569815579M33648355235612318189818957D0051267014431198987665AI0306682791016473984207AA9455911869466244989905AA891774769950514098355S6602422270339822851AA92520470197569821729AA9465321658628474235984067AA9248131571143799812156K0099612794104609809840U020968302053151299822602AF04457437368127699816416AA875098623108399818890AA89996414882036883179821355AI10509419966273012969820802AI0595083961274798 TABLE 3PDIOXINDocument Number 1740956.1Timepoints (hrs): 68Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore15188D16302309121813010011724AI102812711004910015599X7525398784981521009842U948563961210116262010011372AI13799559747121410023192AA8911077211926210012306AA94489845510815021004007AA9260662738643610013185U23055143919029281009841U94856442311315038521002922AA996816133824221003664AI171289450191714610070M58308113938911610024644J036371957144475510015703AB009372103133401001559U28504237127832100193AI176856414713652562100191U0954024955146052100190U095402765442−433510015107AI233220117794703744264410013187U230561806345382110023851AI1368629015540913010020703K03241546517839049210015098M31837431124341001869J03959295024788842510016366AA892888246716161430610021489AA8514431024199109981003693AI01144892713921397100179D178094281473510019129AA943990922684399410018027AF03921257620857241004245AA818692199327073715010023584AA9550717565520390100588X698341923127720325100699U5576511732547916010016367AA8928885011664104765910014231AI072358922159445010018028D38062719212102910021488U3257536213643211004381H3300318731−57531009889AI044621533063317055371006143AI105167792896785538610020429J050351011249923910019443AA892832316725596646410015252AI178605845593421181001127AB003400−111247210010710AI0304946431191596210024590M35299−2413436100293J054993772136410010260S814975891905310021288AI227935124131141016310017831AI012017−10191531004561AI10292711188836610310019322AA8519609646348311810023520AA9553052515127481006016AA8181639538279022326851003062AA998857104212703328987310022727AA9258148316941336598910016364AA8922516431441706410024649AI234950328401242810015379AI6391625911129995006AI2299089754−12119925598U325757913914991698J0267916872601821299918588AA8996355706120799991822AA81784310367299918525AI17679249669198849914495AA8936581168310272789912314AA94559656177502132575995007AI236229528371899917324AF056031117123157499590X53428102415992467AA964789546−4269917359AI0079811137227583613977998594AI01293210145147314199489E007783511550403639921094D1035418205919920311U520348813719996121AA84857311415331599192X8386714771119991174J0265720868318271623992354AA99776325664947522929914479AA85896962022361849920430J0503591206523769922755AA946323436156120709921856AA8585504595509916781AI23452717007473231079913563AI23377341239991235347994511AA94434846041188679916873AI0080158427−8189916345AI01325081655601359922713AA94590473320574996628AI1787936357929176994134AA8512401819948593179911791AI17784315672846761509923699J027499843851330299 TABLE 3QDIOXINDocument Number 1740956.1Timepoints (hrs): 6, 24Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore6143AI1051674317108985043910021288AI22793520226194008810019288AI23130534355−93610022755AA9463237311971164810013619AI17946447021077659924649AI234950276481242799489E00778358463324270994561AI102927919135364999923584AA9550715958920188991698J026791112272180128991169AI17716123362713599488E0071763739231486919920703K032413973780378465991170AI17716138211611350998661AA8186041896812639920705E0118471441385811982999527D285606299020491995492D380614072643655995493S5693644823559549912314AA9455964958114721215489920704M26127548099210069259815252AI178605675118341117989528D28560563162187699815127S5693715004545232529818989K001364129115410597889823851AI13686270340409130978457AI059835115432524972713AA96294351480222909715126D837962608725881456973690AA9990068064082241159719185AI111361914015219716366AA89288818715676103009723682AI234973525136239899723448AA925167447316619667929723449AI1768283104739834704973427AA8922461964385339715743AA996434439132194759715124J0261227345939895489716367AA892888331688510416619619443AA89283224845099614609522866AI23375452459321929523608AI2331907961133952069518597AB0137327621264501229521192AI0097321364551379520464M20406177018512817809511301AI136709635159308140956781AA84875331547152739425041D1401437810652943431AI1765951437257738285942264AI14474125432420999422490AA899289848496211349420779M1518520302579844409418028D3806224518710419318027AF03921221814058339318867D8825011892146282409317768AI1051965091088011509321904M24239389831821921985939157AI1799471131942389314231AI0723584032994456938212AI23180730812051402913937084AI230362811804302039317742AA86630223111851454972939842U9485622841321161631929192AI137345261231616336549219009AA85016414991401100306921529M8168766144452113922536AI17661611592375873389213563AI233773268360212333579215296AI228738944019156929383AI0598241144521209215173AI2318461112292360163922354AA9977632333966746266928130AI0088941344821279112482AI14496518311144649125468M949183534445163712659117614AA8483062402815548911850K028142275250163312019122250AA94354123636124689125469M9491923983191165806918438AA8929864112102409120311U520346940719914791AI17910614413104319121903AA945571150917310956429117817AA89277722446209123576X727571480709614729125057M5849577422259117236AA858903−1062751916619AA818743781170406969115357AI010803289588473911262AB01704422662329111563AI102560−10935389120055AI230762−132570689123606U0578478627532413891 TABLE 3RESTRADIOLDocument Number 1740956.1Timepoints (hrs): 24, 240Non-Non-Discrim-GLGCGenBankGroupGroupGroupGroupinantIDAccMeanSDMeanSDScore7804AI23377110141−4649412313AA945418393636385119179418525AI1767927227201849022604AA945578418891001448882569AA965122469128884272917199AI01304496217117194729010545U21871273219263888984L106522342216644903458AA9978611060134149526990633AI23112795216114142779011404AI237002335622131278914421AA94275121826144478922351AA945867571821318820601X52625269827273958820600AI177004162574792638814737AI008416129017319415258812958AI1771556649611233578724162AI1692798517712573138817590AA8928511501510943909012AI070879277155748270888058AA81847546053649145901379M8367650922188720983AI04490039451756333881126AI23100748822188713203AI2287283332−49588916006AF06259451151625881169AI177161120227238893880AA8932471201476279115259AI17813516327994888570X8244518322128348816943AI236097131924720624598810544D6341122325164538821772AI011179951161209018524AA94601787411211772688714996X16038581822408817431AI07052121318158408714545AA800456791346208719590D873361051862308822350AA9440143191114898872AA851050697102494241881170AI1771611793211455882629Y00396661734328921952AA89153786105920883823AI2331477471255191838917502M121561533287438820755X708711032954378716416AA87509815126107399024779J0386347323113628487574L130391252691438923299AI17683939387186125905711AI04515145521910533238716178AF0353872072014933871373L249071001365198812358AI17066154211521886536AA891834541625148920781U89282721438178723825U3818077124617895082D14015591818228716649AF05189513285−429912587AI2321039533561747412903944AA90068820295653021199716650D4213722910065369624013AI2292601915158589123468AA9260678431754611219114973L1918027911779649122972AB015946701637158817956AA964379110126722903905AI1034036551393851409010002AI13798825361135648815056U60578572911178723500AA860010532319198721103AF03458230854165519116043AA87483027977129279619259AA900613530236−701998810248L23148883232218721504AI1379411572405719300886101AI17075274203123885264AA926107776245621009621703U82591931847229118085AA8586034831−243988172M278868715372396764X8421017217104349417894U252641263658218915684AI171535655123349129936547AI0121818363472251378920741AF08418692212832894477U7782941916138913294AI233731519863461048715685AI2338703761191317392174J041971282950318811850R4698517143051117312882230AA9576432045964339411830AI17909311242156082628723192AA891107327631896090173X15580253411116395778U84410551519198721115AF08662420646706188 TABLE 3GENERALDocument Number 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TABLE 3THYDRAZINEDocument Number 1740956.1Timepoints (hrs) 3, 6, 24Dis-crim-i-GLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore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−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ocument Number 1740956.1Timepoints (hrs): 48, 72Dis-crim-iGLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore1995AF03887011011914071093996381AA8587685132−2349910071AI63905882740229919053D127701102635339915002AI16932729667138549913138AI2335529551123996143AI105167128598805319925746X807784096129917480U315981744576279916993AA79956018835813375998597AA81859323934108379919438AA81945046173301769915872L2813512036389140983895AA8940291313536279819031AI070532442325179810012606M5986117230578230995176AA9987228147−46389926320AI234927139432031981472U26356615−5259922515AA9005828802481143239921092AA800380121311926316859912797AA8007901002228189915003AI16932717945−1529916885AI10518857411016784499912551AI2300565113240789913283M1126618836695303991175X79081−8335063219915517D42145135324318995175AA8189512206248549919004AI175875474124147609920783AI1719662296561409914840AI2376982477971429912736AI2339722287470359817684AA892345113827972998317AA89223413016488178999267AI0723845601041807506992005D269646109192818992505M16235171535852059911465AI236084414601421099820869M320622436467389920816M5840455512320790999223M3615129110098379823321AA8928219411221529920668M320621955351319922511M22670558189−548994914AI11208676415001549918453D1737010715491212991748M8448873148129911422AA799812681611109918387AI237731107282626996366AA858716832207280109984207AA94559114245334592279821066D1058714111682099794U6816815836606227991572AI17882817518812999666M10072601112139914311U106996119810996614AA84838914145974264993121AI00816013755756242986322AA8188011474716229924712E0188411653−617996189AI17802719010941002305996615AA9428899034440120992555D009134205812345997427J0512216727383099475AI2338284418710241969910015AF0832692874313740996532AI23410532259136389915185X629522165764439972M5726317597−21239918354X59859151282331994318AB005900461756994439AA68517544486202469914600AA801076564219111489918709M32397318−5109922690AA9459707547589217999191AI0721076633711275996365AA899163193375237994636AA8994913627452609920879X6529664405002209916809X588281763138279918352Z12298992512189916416AA87509825157107379820123AI07221415203141079910016AF0832692554196429918038U399438612223609825471M96630255369945984026AI2338359581743751329824237AA817726943204186113995899AI1700382571021267313992799AI0137785684652259812118AA8927755447122191999583AI0711854351055169983916AI1699474668816244059820354M143693193459519824219L2784369769300106981221D1144555180238399 TABLE 3VINDOMETHACINDocument Number 1740956.1Timepoints (hrs): 6, 24Dis-crim-i-GLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore17588AA8928496191427939712AI176836221481339317908AI0141631423167629316579AA95714312215205649221488U3257575944279212191D2607362727289113768AA8197928332−16589219584X1390519525116449216684D1744536832285809110245AI0597016219135529124596X16044116883339020652L1446349429149017379M6238821433115619017573AI0131322919148100908274AI0592707817152599118908AA849426116272521579010829AI04446728653259024219L27843469763011109211842AA8586174872613903847AA89203675104620901822AA817843102966298925644U779314033927510490515X6385487958218921524AI012014−61233289018165AA89225950730138914827AI23740431209748901427L3864469839228918002AI043655122323022218678919942AF0085542072513745909598H33832247391561218921491AF04095411498822893365AI0089194241287652329017214AI63900817929119409122069AA94634933757516129896537AI2338175646−591129024508M3464317425116369020819M812251141482258916610D285572133114058896788AI2286462414213875899498AI07316475134419906016AA81816312774062259787897063M129191473092659024690J05571581135178925670X07648170481085391959D380726018281989353L325911514454609014303AI2311594501102257590870U66478581129169114768AI2359122636413777904250AA81870021831135449213364AI17060620827134419321708AA956930129187129934527AA892774821543189518327AA799537125325426892554D009131172466208918068S7967691215218907197AI171962742034218925508S676203618−6159118400AA7999911223559278924570M955786441−22309111827AA8594689720472189155U32681116355228919866AJ0054247349−1279017953AA89409023244151389323587AI1765981232962299015487AI176351145357433894043AI2278521103856289017634AJ22335532571157549015933AA87525324545153449322336AA89392491189389521683M651491376715249317377X13058173568146899821AI180114141247031911379M83676611022189419411AA893667137554223921641E034282033511341892005D29646711829199020161X546861275428379011203AA892554112325222902557AI176820922934169214425AI17775514475564284059220090AI6393532096211237916085AI171990162505450903504AI10465947677285909114501AI1757781093041239021111AI227832844014279119884AI170501233126654852830905384AA8910411404827419018495AI639042511518169313166AI178736244928056911844M3396223474114449122566AI177122113354633891841AI1132891886152409217589AA892851143494136916226AA81852170252520913773AA9983561928156479123855AI236773343681646896 TABLE 3WLipopolysaccharideDocument Number 1740956.1Timepoints (hrs): 24Dis-crim-i-GLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore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−621238048510020839AA891729194520379928910013563AI2337734552512463779919018M8687064429297829912320AA946149119312665219918606X535041203885431699925679X1501315269563724499154U3268150258160459925719X6214616801227832739917324AF0560318219316739925052L22190161430223689924577X15515316171066642569921657X613812029431546187991641E0342827515113419923651M1465666171947996614AA84838911927971268991598U301861011515349917284J0282766717939997858AI04365414952−2229925747X8144893289321989916204X0642313251355631589921765AI2336961341237259911416AI1721852832110937992997AI0305458863481239917175X583891068834661319921074AI013890100795404136999215AA9251161095215269109994914AI11208649194991559922515AA900582418410451052159916173AA9570032867220269914929AI1703533738211471995175AA818951345774853994365AI07020072467259120991678M966742213128339915872L2813573253881419920862E01415621625175992744D87991510371875499 TABLE 3XPHENOBARBITALDocument Number 1740956.1Timepoints (hrs): 24, 48Dis-crim-i-GLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore20913M23995268921262252219912160AA81841214509180010658559920384D1734927024101451379925055M11251593010861943109920914M23995265210371982089916619AA99754471324633269912158L00320592511681833119924860M135062060460306181995102AA925211617308−41239925056M13234738713707085639912155J00728686312524944839915695D108913811−15159912156K00996859220333895809912157K01721900819434357309918989K00136451361010507669920915AF00189819657733952259917541M26125403452111307129910152AI059110136411217991795L2420722407044162909815879AI22831361111830880981794X6440183812185148312469820707U880361399196470218982486AA9648711196262477164984312AB0106355212675567981793D13912417211318485639812556AI18037647216961839821903AA94557136447301075593981797X62086614516351237942981796L242078823392151179816310L136007034−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−138212094634K01932252231511075979421014J039141545206768344946633AI228893175917312853159421798AA926365245532716953719417805U0627418091918984019423322AA892821693664371279422884AI0107552744516752944314AF01059757152374959415955AI2322943313018984935622X05834126214811034969325725X6266027057137569320090AI639353637113389321015X042295744999202714279324112AI00877321643661154537936000AA8180885539−23269321013J0281058311552182614299325525S7250522504659785059318473AI1689759422424191379321039J031907211762001189316274D102616084624307833249323445M847197829212889317676V01235454531823082052938872AA8510509982824922359222992AA9968803593823173924573AI17961310441368963599219040J0362718346369216019AI00849848315614790927926AI043913163378256924186AA945169500144526462383922681AA9010431272173369221038J03190734178243128929697AI07164282271519921354D38065373552191359219271AI2315661353627192923143AI23240825020360949220385X54793939766692029218939AA945875673205176110929841U948562341150150486492 TABLE 3YTACRINEDocument Number: 1740956.1Timepoints (hrs): 6Dis-crim-i-GLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore18389AA79949810882633996236AA81862724153981447986919AI0104619721682792429814996X160381848621389814997J035726121342371479817050AA7994662793117534988210S6196030833125679812704AI009194325099314463359720744J04171577602771819722513M23566425292−596119721063D899831342555259721209AI17177236411685879713369D2113224214158329722512M2267010124395897373D86086189213911399723606U057845715732614497344AI008865295565311395009711215AA817921−9539114869721923AA8912605572016972939AA9968853622188829719410AA893667153109526962899AA9966988245379624284M94287942839189626190AI072578126139−166107964107AA899109829178719620772U60882107963279622396AA8598061464104299616701AI0088381112132222170296633AI231127880671409280966263AI00966613211266899621980AA893454577234041159619412AA84922264170385121961968M837453461389612516AI1796511418164893195967552AI045802684249412679614393AI0113673968830965020AA9247681609251729610545U2187130428193639613932AI230988−49356854962569AA965122183114881271951843M3396283124019959432AI07291411427482995798U382534862211956352AA9976003010−1430956060AA818702313325001079525567S851842866813378955696AI04511614215273969520850AA8999564774579517449AI23725895657239521341AA85019539377822297952242AI012635450496223388649523243AA85180351213817117959515786AI0139241362428787951991M831966811371495410AI0089744020169779522514X139831243263709513975AA8504506914162689517590AA8928511863110943951426Z4822519415133309521799AI102576−15524239519575AA8508141302328898952250AI0123547332011786689953145AA997237278496071969516703AI17930059112212123739510573AI10100316422804894960D1002612014202509410555AA9001982928371225946072AI228630109127320234659419370AA9637971364327471944592J026462112014939944879AA9238522513113559424427J031701551511420944232AI01295825179552947063M129191512292659422196U217191172457329419085AA892598168299037944183AI1027899516167449416680AA965190120443621369421062AI04363110118311609420L2626840632284909418507AI17555110051116972099411166AA80134626678530135941583U0720165938179418910AI23241942612811984319418714AI0131942817238939410176AA8195302427744799942486AA964871162744851789423451AA9252431914241599423577AA9555131835126943282AA81811390272077094 TABLE 3ZVALPROATEDocument Number 1740956.1Timepoints (hrs): 24, 96Dis-crim-i-GLGCGenBankGroupGroupNonGroupNonGroupnantIDAccMeanSDMeanSDScore12829AA85869554724393939623698J0274949147299365951774J037542438109512698AI1706651641774303942179AA8482705921053521029414937AI23715919621120389422604AA94557818393349874469419358AI009675269199993439935887AI17909916551861689320711AA824267291451271709315907AA99642218213270899323203AA79997117021107369321656AA8002026653621933362AA99809227881399323579AI171802801216731309226109AA997009394109153291923279AI10322410111167162029217290AA89178525743166609217237X1614528031208449212964AI23622739531241969264M606552052813436924914AI112086727594961579221094D1035434245204919220715X0725952282313353912373AA964455145312871169123228AI23544611106315575749117289AA8917851961712853912140AI1722721652986479118637AA858651110518220456149119433AA81977620032105799117529AI17146020539136419117758K03249411533083499121068AI17567528310121135913848AA89230634121113911301J025854255810169069117187AA800315801243239122379AI231448254554792059115148AA859325702111483132917756AA892864881541359123886AA963008118918162919644AI0714102812−13279110073AI05851539556519115926AB012933363184711879016780X626603392026910390725U62316961753259014332AJ00104448235249017107AI178582127531325048319021285AA849898−764285144907381AI0291327612127419018168AA9429950631339015980AA866426104673289015849AI0080742282615769909192AI13734583612816456569015041AB01653232121028904312AB01063598215984905712AI04515439895489015638AA875633891051299020795AA94439719434123869011998AA89282861739269020980AA7996331021767229014504AA799804177181311079018002AI04365513971272219868907186AI072833498363771229016721D306472932823550895094AA9251655089445899754AI112194380482201308911162AI00818328559368925725X6266018316138578920846AI231140157928327627968922308AA89953548285778273892337AA964307838122418922491AA89928916716243948917809AA6864616374324896912D8503523114180458914506H3258429812253718916945AA92554146093669153894360H3181313025233101897784J0459116818124358922077AI17709996195826898977AA79974162541178922992AA9968801471923373894271AA9256032497859146891728D1647924917220808921785AI17731214620218568921531M9159535926418921803AI00828420451374129896975AI176229391393291628912233AI0134742433239313589811D6370445312532163891391X66366141710429892103AA85113513564152464709897783AA8920699410603089 TABLE 3AAVALPROATEDocument Number 1740956.1Timepoints (hrs): 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TABLE 3BBWY-14643Document Number 1740956.1Timepoints (hrs): 24, 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DONNA","valueNormalised":"Mendrick Donna"},"inventorship":null},{"name":{"value":"PORTER MARK","valueNormalised":"Porter Mark"},"inventorship":null},{"name":{"value":"JOHNSON KORY","valueNormalised":"Johnson Kory"},"inventorship":null},{"name":{"value":"HIGGS BRANDON","valueNormalised":"Higgs Brandon"},"inventorship":null},{"name":{"value":"CASTLE ARTHUR","valueNormalised":"Castle Arthur"},"inventorship":null},{"name":{"value":"ELASHOFF MICHAEL","valueNormalised":"Elashoff Michael"},"inventorship":null}],"inventorships":[],"unmatchedInventorships":[],"activeUserHasInventorship":false},"simpleFamilyId":192512482,"citesPatentCount":28,"countrySpec":{"countryName":"USA","description":"GRANTED PATENT AS SECOND PUBLICATION [FROM 2001 ONWARDS]","rule":"pubdate:AFTER:01-01-2001","docType":"GRANTED_PATENT"},"pageTitle":"US 7590493 B2 - Methods for determining hepatotoxins","documentTitle":"Methods for determining hepatotoxins"},"claims":{"source":"xml_claims","claims":[{"lines":["A method for determining whether a test compound is a hepatotoxin, comprising:\n
(a) exposing liver tissue or liver cells to the test compound;\n
(b) preparing a normalized gene expression profile of at least ten genes for said liver tissue or liver cells, wherein the gene expression profile contains the differential gene expression levels for said at least ten genes upon exposure to the test compound, and wherein said at least ten genes are listed in one of Tables 3-3DD;\n
(c) comparing the gene expression profile to a hepatotoxicity model, the hepatotoxicity model comprising:\n\n(i) the normalized mean expression levels of said at least ten genes in liver tissue or liver cells exposed to a known hepatotoxin,\n(ii) the normalized mean expression levels of said at least ten genes in liver tissue or liver cells not exposed to a hepatotoxin, and\n(iii) information from one or more of Tables 3-3DD; and\n
(d) scoring the comparison to determine whether the test compound is a hepatotoxin."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the gene expression profile contains the differential gene expression levels for at least 20 genes listed in one of Tables 3-3DD, and wherein the hepatotoxicity model comprises the gene expression levels in said one of Tables 3-3DD."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein said gene expression profile is generated by hybridization of nucleic acids to a microarray, and is normalized for hybridization conditions, label intensity, and reading efficiency prior to comparison."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the hepatotoxicity model comprises all the information in one of Tables 3-3DD."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the liver tissue or liver cells are exposed to the test compound in vivo and the hepatotoxicity model is generated by exposure of liver tissue or liver cells to the known hepatotoxin in vivo."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the known hepatotoxin is associated with at least one of hepatitis, liver necrosis, protein adduct formation and fatty liver."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the known hepatotoxin is one or more of acetominophen, acyclovir, ANIT, AY-25329, bicalutamide, carbon tetrachloride, clofibrate, cyproterone acetate, diclofenac, diflunisal, dioxin, estradiol, hydrazine, indomethacin, LPS, phenobarbitol, tacrine, valproate, WY-14643, and zileuton."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the gene expression profile contains the differential gene expression levels for at least 30 genes listed in one of Tables 3-3DD, and wherein the hepatotoxicity model comprises the gene expression levels in said one of Tables 3-3DD."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the gene expression profile contains the differential gene expression levels for at least 50 genes listed in one of Tables 3-3DD, and wherein the hepatotoxicity model comprises the gene expression levels in said one of Tables 3-3DD."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the comparison is scored by determining whether the test compound induces a change in expression of the at least 10 genes in the same direction as the known hepatotoxin."],"number":10,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}