Compositions And Methods For Use In Oncology

  • Published: Dec 24, 2014
  • Earliest Priority: Jun 20 2013
  • Family: 21
  • Cited Works: 5
  • Cited by: 0
  • Cites: 1
  • Additional Info: Cited Works Full text

The present invention relates to compositions and methods for use in medical diagnostic and patient monitoring, typically in the context of therapy, in particular in the context of oncology to optimize tumor bed local irradiation. It more particularly relates to a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates, wherein i) the density of each nanoparticle and of each nanoparticles aggregate is of at least 7 g/cm3, the nanoparticle or nanoparticles aggregate comprising an inorganic material comprising at least one metal element having an atomic number Z of at least 25, more preferably of at least 40, each of said nanoparticle and of said nanoparticles aggregate being covered with a biocompatible coating; ii) the nanoparticles and/or nanoparticles aggregates concentration is of at least about 1% (w/w); and iii) the apparent viscosity at 2 s-1 of the gel comprising nanoparticles and/or nanoparticles aggregates, is between about 0.1 Pa.s and about 1000 Pa.s when measured between 20°C and 37°C.

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Document History
  • Publication: Dec 24, 2014
  • Application: Jun 19, 2014
    WO EP 2014062976 W
  • Priority: Jun 20, 2013
    EP EP 13305830 A
  • Priority: Jun 20, 2013
    US US 201361837406 P

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