Use Of Pro-inflammatory Compounds For Promoting Bone Formation


The present invention provides methods, uses and compounds for promoting bone formation in a patient at a site in need thereof by the provision of a pro-inflammatory compound at the site. The site is generally a site of injury or a site of surgical intervention in the patient. Exemplary compounds include pro-inflammatory : cytokines. Inhibitors of indoleamine 2, 3, dioxygenase 1 are also provided in the methods and uses of the invention.


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