Mutational Signatures In Cancer

Abstract

The present invention relates to the identification of a number of mutational signatures in patients with cancer. The mutational signatures include new base substitution signatures and rearrangement signatures. The signatures were identified by whole genome sequencing of 560 breast cancers and the application of new and existing mathematical methods to the base substitution and rearrangements found in those cancers.


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Document History
  • Publication: Nov 9, 2017
  • Application: Apr 28, 2017
    WO EP 2017060289 W
  • Priority: May 1, 2016
    GB GB 201607629 A

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