Method For The In Vitro Detection Of A Predisposition To The Development Of Alterations In Ovarian Function

  • Published: Jul 23, 2008
  • Earliest Priority: Sep 13 2005
  • Family: 8
  • Cited Works: 0
  • Cited by: 9
  • Cites: 0
  • Sequences: 21
  • Additional Info: Sequence

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The invention relates to a method for the in vitro detection of a predisposition to the development of alterations in ovarian function. The inventive method is based on the detection of polymorphisms -673C>T, -9C>G, IVS1+905A>G and N103S of gene BMP15 and combinations of same. The invention can be used for the diagnosis or prognosis of a predisposition in women to alterations in ovarian function, such as the onset of menopause at an unusually young age, including both early menopause and premature ovarian failure, a reduction in the reproductive window or the development of ovarian hyperstimulation syndrome (OHS) following controlled ovarian stimulation (COS) with FSH in treatments to increase fertility.


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Document History
  • Publication: Jul 23, 2008
  • Application: Aug 29, 2006
    EP EP 06807950 A
  • Priority: Aug 29, 2006
    ES ES 2006070130 W
  • Priority: Sep 13, 2005
    ES ES 200502225 A

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