Methods For Controlling Inflammatory And Immunological Diseases


The present invention provides methods for generating mucosal tissue homing immunosuppressive T-cells comprising treating naïve T-cells with retinoids and/or retinoid agonists. Methods are also provided for treating a mammal having an inflammatory or immunological disease by administering a therapeutically effective dose of retinoids and/or retinoid agonists. Additional methods are also provided for boosting the immune system of a mammal by inhibiting the generation of immunosuppressive T-cells by administering a therapeutically effective dose of a retinoid receptor antagonist to the mammal.

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Document History
  • Publication: Nov 13, 2008
  • Application: May 1, 2008
    WO US 2008/0062125 W
  • Priority: May 1, 2007
    US US 91516207 P

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