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The invention concerns in particular the methods for demonstrating mutations in this gene which are linked with risks of CADASIL outbreak. The invention also concerns models and products for treating CADASIL and related diseases.","lang":"en","source":"DOCDB_TRANSLATION","data_format":"DOCDBA"}],"fr":[{"text":"
La présente invention concerne le gène Notch3 et la protéine correspondante qui sont impliqués dans le CADASIL.
L'invention concerne notamment les méthodes de mise en évidence des mutations dans ce gène, celles-ci étant liées à des risques de survenue du CADASIL.
La présente invention concerne également des modèles permettant le traitement du CADASIL et des maladies apparentées.