Knsls As Modifiers Of The Apc And Axin Pathways And Methods Of Use

Abstract

Human KNSL genes are identified as modulators of the APC and AXIN pathways, and thus are therapeutic targets for disorders associated with defective APC and AXIN function. Methods for identifying modulators of APC and AXIN, comprising screening for agents that modulate the activity of KNSL are provided.


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Document History
  • Publication: Jun 9, 2005
  • Application: Nov 23, 2004
    WO US 2004/0039788 W
  • Priority: Nov 24, 2003
    US US 52458803 P

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