WO 2019/048639 A1 - Mixed-lineage Kinase Domain-like Protein In Immunotherapeutic Cancer Control - The Lens

Mixed-lineage Kinase Domain-like Protein In Immunotherapeutic Cancer Control

Published: Mar 14, 2019
Earliest Priority: Sep 07 2017
Family: 2
Cited Works: 115
Cited by: 0
Cites: 5
Sequences: 11
Additional Info: Cited Works Full text Published Sequence

Data obtained from: EPO Sequence Listings EMBL-EBI Pat WIPO-PCT

11 sequences found in this patent (in total)

Download sequences in fasta format: 11 peptides

Displaying 1 - 10 of 11 sequences

SEQ ID NO

Length

Sequence Type

Locations

Declared organism

Determined organism

Occurrence

Tools

SEQ ID NO

Length

472

Sequence Type

peptide

Locations

Fulltext

Declared organism

Mus musculus (house mouse)

Determined organism

Occurrence

6 times in PatSeqDB

in 2 families
in 6 documents

Tools

SEQ ID NO

Length

471

Sequence Type

peptide

Locations

Fulltext

Declared organism

Homo sapiens

Determined organism

Homo sapiens
Homo sapiens
Public DB hit
GI:22749323
NP_689862
1 of 3 hits reported for Homo sapiens.

Hit length
471 aa

E Value
0E0

BLAST Score
971.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
NP_689862

100% cov

Alignment Length
471 aa

CIGAR string
471M mismatches: 0 - insertions: 0 - deletions: 0
synthetic construct
synthetic construct
Public DB hit
GI:61354502
AAX41010

Hit length
472 aa

E Value
0E0

BLAST Score
968.4 bits

Similarity

99.79%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
AAX41010

99.79% cov

Alignment Length
471 aa

CIGAR string
245MN225M mismatches: 1 - insertions: 0 - deletions: 0
Pan troglodytes
Pan troglodytes
Public DB hit
GI:114663654
XP_001137657

Hit length
471 aa

E Value
0E0

BLAST Score
953.7 bits

Similarity

99.58%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XP_001137657

100% cov

Alignment Length
471 aa

CIGAR string
248MN31MN72MN15MN17MN30MN5MNMNMN17MN7MN16M mismatches: 11 - insertions: 0 - deletions: 0
Macaca mulatta
Macaca mulatta
Public DB hit
GI:109129198
XP_001108382

Hit length
470 aa

E Value
0E0

BLAST Score
877.9 bits

Similarity

95.54%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XP_001108382

100% cov

Alignment Length
471 aa
Equus caballus
Equus caballus
Public DB hit
GI:149699821
XP_001498618

Hit length
474 aa

E Value
2.44E-177

BLAST Score
627.1 bits

Similarity

82.13%

Coverage

99.58%

Alignment (schematic)

SEQ ID NO 2

99.58% cov
XP_001498618

98.52% cov

Alignment Length
470 aa
Bos taurus
Bos taurus
Public DB hit
GI:119909766
XP_001256760

Hit length
468 aa

E Value
5.52E-173

BLAST Score
612.8 bits

Similarity

80.43%

Coverage

99.58%

Alignment (schematic)

SEQ ID NO 2

99.58% cov
XP_001256760

99.79% cov

Alignment Length
470 aa
Rattus norvegicus
Rattus norvegicus
Public DB hit
GI:293343366
XP_002725461

Hit length
464 aa

E Value
9.14E-161

BLAST Score
572 bits

Similarity

77.73%

Coverage

98.94%

Alignment (schematic)

SEQ ID NO 2

98.94% cov
XP_002725461

97.63% cov

Alignment Length
467 aa
Mus musculus
Mus musculus
Public DB hit
GI:110626037
NP_083281
1 of 3 hits reported for Mus musculus.

Hit length
464 aa

E Value
2.11E-159

BLAST Score
567.8 bits

Similarity

77.4%

Coverage

99.36%

Alignment (schematic)

SEQ ID NO 2

99.36% cov
NP_083281

98.06% cov

Alignment Length
469 aa

Occurrence

80 times in PatSeqDB

in 19 extended families
(10 referenced in claims)
in 22 simple families
(11 referenced in claims)
in 72 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

2323 times in PatSeqDB

in 565 extended families
(21 referenced in claims)
in 631 simple families
(22 referenced in claims)
in 2187 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

2 times in PatSeqDB

in 2 families
in 2 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

19 times in PatSeqDB

in 5 families
in 17 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

19 times in PatSeqDB

in 5 families
in 17 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

19 times in PatSeqDB

in 5 families
in 17 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

19 times in PatSeqDB

in 5 families
in 17 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

19 times in PatSeqDB

in 5 families
in 17 documents

Tools

SEQ ID NO

Length

Sequence Type

peptide

Locations

Fulltext

Declared organism

Artificial

Determined organism

Occurrence

60 times in PatSeqDB

in 13 extended families
(2 referenced in claims)
in 16 simple families
(2 referenced in claims)
in 54 documents

Tools

11 sequences found in this patent (in total)

Filter sequences

Displaying 1 - 10 of 11 sequences

Homo sapiens

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

synthetic construct

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

Pan troglodytes

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

Macaca mulatta

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Equus caballus

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Bos taurus

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Rattus norvegicus

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Mus musculus

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Mus musculus

Public DB hit