Methods Of Treatment Of Autoimmune Diseases Using Humanized Immunoglobulin Reactive With B7-2

Data obtained from: EMBL-EBI Pat DDBJ Pat USPTO Fulltext NCBI GenBank
52 sequences found in this patent (in total)

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Download sequences in fasta format: 26 peptides 26 nucleotides

Displaying 1 - 10 of 52 sequences

SEQ ID NO
Length
Sequence Type
Locations
Declared organism
Determined organism
Occurrence
Tools
SEQ ID NO
1
Length
405
Sequence Type
nucleotide
Locations
Detailed Description, Drawings
Declared organism
Murine anti-B7-2 heavy chain
Determined organism
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:8925314
      AF239196
      1 of 2 hits reported for synthetic construct.
    • Hit length
      805 bp
    • E Value
      3.24E-165
    • BLAST Score
      590.2 bits
    • Similarity
      92.94%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      AF239196
      50.68% cov
    • Alignment Length
      411 bp
    • CIGAR string
      10MN20MD2MI53MN15M2N53MN2MN49MN2MN4MN3MN127MNIM2N2D5M2I2MIMNI11MN5MN3MNM2N4MN9M mismatches: 20 - insertions: 6 - deletions: 3
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:62148947
      AB121776
      1 of 22 hits reported for Mus musculus.
    • Hit length
      372 bp
    • E Value
      1.18E-154
    • BLAST Score
      555.1 bits
    • Similarity
      96.71%
    • Coverage
      82.22%
    • Alignment (schematic)

      SEQ ID NO 1
      82.22% cov
      AB121776
      89.52% cov
    • Alignment Length
      334 bp
    • CIGAR string
      18H13MD2MI53MN15M2N53MN2MN49MN2MN4MN3MN127M54H mismatches: 9 - insertions: 1 - deletions: 1
  • Mus sp.

    Mus sp.

    • Public DB hit
      GI:243052
      S78361
    • Hit length
      462 bp
    • E Value
      3.33E-145
    • BLAST Score
      523.7 bits
    • Similarity
      90.17%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      S78361
      87.01% cov
    • Alignment Length
      407 bp
Occurrence
17 times in PatSeqDB
Tools
SEQ ID NO
2
Length
135
Sequence Type
peptide
Locations
Detailed Description, Drawings, Summary
Declared organism
Murine anti-B7-2 heavy chain
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:80474423
      AAI08385
      1 of 21 hits reported for Mus musculus.
    • Hit length
      482 aa
    • E Value
      1.26E-62
    • BLAST Score
      243.4 bits
    • Similarity
      89.78%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      AAI08385
      28.42% cov
    • Alignment Length
      137 aa
    • CIGAR string
      3MN7MN22MN17M2N6MN7MNM2N2MN2MN39M3NM2I2N6MN4MN mismatches: 18 - insertions: 2 - deletions: 0
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:8925315
      AAF81417
      1 of 2 hits reported for synthetic construct.
    • Hit length
      261 aa
    • E Value
      4.51E-62
    • BLAST Score
      241.5 bits
    • Similarity
      91.79%
    • Coverage
      98.52%
    • Alignment (schematic)

      SEQ ID NO 2
      98.52% cov
      AAF81417
      51.34% cov
    • Alignment Length
      134 aa
    • CIGAR string
      3MN7MN17MN4MN17M2N16M2NM2N42MI3NMN7M2N2M2H mismatches: 16 - insertions: 1 - deletions: 0
  • Mus sp.

    Mus sp.

    • Public DB hit
      GI:243053
      AAB21040
    • Hit length
      134 aa
    • E Value
      1.18E-58
    • BLAST Score
      229.9 bits
    • Similarity
      90.37%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      AAB21040
      100% cov
    • Alignment Length
      135 aa
  • Mus musculus domesticus

    Mus musculus domesticus

    • Public DB hit
      GI:899071
      AAB00849
    • Hit length
      152 aa
    • E Value
      5.95E-51
    • BLAST Score
      204.5 bits
    • Similarity
      81.29%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      AAB00849
      91.45% cov
    • Alignment Length
      139 aa
Occurrence
18 times in PatSeqDB
Tools
SEQ ID NO
3
Length
396
Sequence Type
nucleotide
Locations
Detailed Description, Drawings
Declared organism
Murine anti-B7-2 light chain
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:1438580
      U62050
      1 of 20 hits reported for Mus musculus.
    • Hit length
      406 bp
    • E Value
      0E0
    • BLAST Score
      671.5 bits
    • Similarity
      98.43%
    • Coverage
      96.21%
    • Alignment (schematic)

      SEQ ID NO 3
      96.21% cov
      U62050
      93.84% cov
    • Alignment Length
      381 bp
    • CIGAR string
      15H41MN12MN95MN177MN15MN29MN6M mismatches: 6 - insertions: 0 - deletions: 0
  • Mus musculus domesticus

    Mus musculus domesticus

    • Public DB hit
      GI:576599
      M28833
      1 of 5 hits reported for Mus musculus domesticus.
    • Hit length
      462 bp
    • E Value
      0E0
    • BLAST Score
      660.4 bits
    • Similarity
      96.72%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 3
      100% cov
      M28833
      85.71% cov
    • Alignment Length
      396 bp
    • CIGAR string
      53MN15MN87MN7MN6MN170MN16M3N8MN2MN2MN14MN3M mismatches: 13 - insertions: 0 - deletions: 0
Occurrence
17 times in PatSeqDB
Tools
SEQ ID NO
4
Length
132
Sequence Type
peptide
Locations
Detailed Description, Drawings, Summary
Declared organism
Murine anti-B7-2 light chain
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:226887667
      2ZUQ_B
      1 of 22 hits reported for Mus musculus.
    • Hit length
      239 aa
    • E Value
      2.08E-69
    • BLAST Score
      265.8 bits
    • Similarity
      99.24%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      2ZUQ_B
      55.23% cov
    • Alignment Length
      132 aa
    • CIGAR string
      23MN31MN58MN17M mismatches: 3 - insertions: 0 - deletions: 0
  • Mus musculus domesticus

    Mus musculus domesticus

    • Public DB hit
      GI:576600
      AAA53292
      1 of 2 hits reported for Mus musculus domesticus.
    • Hit length
      148 aa
    • E Value
      7.27E-67
    • BLAST Score
      257.3 bits
    • Similarity
      97.73%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      AAA53292
      89.19% cov
    • Alignment Length
      132 aa
    • CIGAR string
      23MN28MN2MNMN56MN5MN11M mismatches: 6 - insertions: 0 - deletions: 0
  • Rattus sp.

    Rattus sp.

    • Public DB hit
      GI:1326410
      AAB35891
    • Hit length
      134 aa
    • E Value
      3.52E-60
    • BLAST Score
      235 bits
    • Similarity
      92.42%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 4
      100% cov
      AAB35891
      98.51% cov
    • Alignment Length
      132 aa
Occurrence
18 times in PatSeqDB
Tools
SEQ ID NO
5
Length
405
Sequence Type
nucleotide
Locations
Detailed Description, Drawings, Summary
Declared organism
Homo sapiens
Determined organism
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:8925314
      AF239196
      1 of 2 hits reported for synthetic construct.
    • Hit length
      805 bp
    • E Value
      7.57E-107
    • BLAST Score
      396.3 bits
    • Similarity
      84.65%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 5
      100% cov
      AF239196
      50.68% cov
    • Alignment Length
      417 bp
    • CIGAR string
      10MN20MD2MIMN33M2N10MN8M2N2MN7MDMI10MNMN8MNMN30MN2MN6MI2MD3MIMD2MN2MNMN2MNMN2MN19MN2MN4MN3MN54MN2M2NMN21MDMNDMN2I4MN10MNMN3MNMN15MNIM2N2D5M2I2MIMNI11MN5MN3MI2MND4MN9M mismatches: 43 - insertions: 12 - deletions: 9
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:80474422
      BC108384
      1 of 22 hits reported for Mus musculus.
    • Hit length
      1,556 bp
    • E Value
      7.68E-97
    • BLAST Score
      363.1 bits
    • Similarity
      85.52%
    • Coverage
      86.91%
    • Alignment (schematic)

      SEQ ID NO 5
      86.91% cov
      BC108384
      22.62% cov
    • Alignment Length
      359 bp
    • CIGAR string
      10MN20MD2MIMN33M2N10MN4M2N2M2N2MN7MDMI10MNMN8MNMN28MN4MN6MI2MD3MIMD2MN4MN2MNMN2MN12MN6MN2MN8M2N7MN6MN38MN2MDMIMN21MDMNDMN2I4MN10MNMN3MNMN5MN10M53H mismatches: 38 - insertions: 7 - deletions: 7
  • Mus sp.

    Mus sp.

    • Public DB hit
      GI:243052
      S78361
    • Hit length
      462 bp
    • E Value
      7.79E-87
    • BLAST Score
      329.8 bits
    • Similarity
      81.84%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 5
      100% cov
      S78361
      87.01% cov
    • Alignment Length
      413 bp
Occurrence
17 times in PatSeqDB
Tools
SEQ ID NO
6
Length
135
Sequence Type
peptide
Locations
Claims, Drawings, Summary
Declared organism
Homo sapiens
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:80474423
      AAI08385
      1 of 9 hits reported for Mus musculus.
    • Hit length
      482 aa
    • E Value
      3.1E-54
    • BLAST Score
      215.3 bits
    • Similarity
      85.4%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      AAI08385
      28.42% cov
    • Alignment Length
      137 aa
    • CIGAR string
      3MN7MN11MN3MNM3N2MN3MN3MN9M2N2MNM2NM2N5MNM2N2MN2MN16MN7M2NMN3MNMN5M3NM2I2N11MN mismatches: 34 - insertions: 2 - deletions: 0
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:8925315
      AAF81417
    • Hit length
      261 aa
    • E Value
      2.98E-52
    • BLAST Score
      208.8 bits
    • Similarity
      84.33%
    • Coverage
      98.52%
    • Alignment (schematic)

      SEQ ID NO 6
      98.52% cov
      AAF81417
      51.34% cov
    • Alignment Length
      134 aa
    • CIGAR string
      3MN7MN11MN3MN2M2N2MN3MN3MN9M2N2MNM5N7M2NM2N19MN7M2NMN3MNMN5MI3NMN7M2N2M2H mismatches: 33 - insertions: 1 - deletions: 0
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:186192
      AAA59427
      1 of 10 hits reported for Homo sapiens.
    • Hit length
      145 aa
    • E Value
      1.65E-51
    • BLAST Score
      206.5 bits
    • Similarity
      79.29%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      AAA59427
      96.55% cov
    • Alignment Length
      140 aa
    • CIGAR string
      MNM5N3M2N3MN17MN14MN2M2N8MN3MNMN2M4N2MNMN3MNM2NMNMNMNMN22M2NM5IMN13M mismatches: 32 - insertions: 5 - deletions: 0
  • Mus musculus domesticus

    Mus musculus domesticus

    • Public DB hit
      GI:598321
      AAA59059
      1 of 2 hits reported for Mus musculus domesticus.
    • Hit length
      150 aa
    • E Value
      2.72E-51
    • BLAST Score
      205.7 bits
    • Similarity
      81.75%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      AAA59059
      91.33% cov
    • Alignment Length
      137 aa
  • Callithrix jacchus

    Callithrix jacchus

    • Public DB hit
      GI:22036558
      AAM89689
      1 of 3 hits reported for Callithrix jacchus.
    • Hit length
      162 aa
    • E Value
      4.48E-51
    • BLAST Score
      204.9 bits
    • Similarity
      80%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 6
      100% cov
      AAM89689
      86.42% cov
    • Alignment Length
      140 aa
Occurrence
18 times in PatSeqDB
Tools
SEQ ID NO
7
Length
396
Sequence Type
nucleotide
Locations
Detailed Description, Drawings, Summary
Declared organism
Homo sapiens
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:1438580
      U62050
      1 of 20 hits reported for Mus musculus.
    • Hit length
      406 bp
    • E Value
      1.15E-154
    • BLAST Score
      555.1 bits
    • Similarity
      92.95%
    • Coverage
      96.21%
    • Alignment (schematic)

      SEQ ID NO 7
      96.21% cov
      U62050
      93.84% cov
    • Alignment Length
      383 bp
    • CIGAR string
      15H35MN5MN12MN2MN11M3N8M2I3MN3M2D8MN2MN6MN42MN38MN60M2N42MN14MN18MN15MN12M2N10MN4MN6M mismatches: 23 - insertions: 2 - deletions: 2
  • Mus musculus domesticus

    Mus musculus domesticus

    • Public DB hit
      GI:576599
      M28833
      1 of 4 hits reported for Mus musculus domesticus.
    • Hit length
      462 bp
    • E Value
      2.49E-151
    • BLAST Score
      544 bits
    • Similarity
      91.48%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 7
      100% cov
      M28833
      85.71% cov
    • Alignment Length
      399 bp
    • CIGAR string
      50MN2MN15MN2MN11M3N8M2I3MN3M2D8MN2MN6MN34MN7MN6MN31MN60M2N42MN14MN18MN16M3N8M2NI3MND6MN7MN3M mismatches: 28 - insertions: 3 - deletions: 3
  • Mus sp.

    Mus sp.

    • Public DB hit
      GI:688164
      S74056
    • Hit length
      337 bp
    • E Value
      3.34E-125
    • BLAST Score
      457.2 bits
    • Similarity
      91.82%
    • Coverage
      82.83%
    • Alignment (schematic)

      SEQ ID NO 7
      82.83% cov
      S74056
      97.33% cov
    • Alignment Length
      330 bp
Occurrence
17 times in PatSeqDB
Tools
SEQ ID NO
8
Length
132
Sequence Type
peptide
Locations
Claims, Drawings, Summary
Declared organism
Homo sapiens
Determined organism
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:226887667
      2ZUQ_B
      1 of 16 hits reported for Mus musculus.
    • Hit length
      239 aa
    • E Value
      2.17E-63
    • BLAST Score
      245.7 bits
    • Similarity
      95.45%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 8
      100% cov
      2ZUQ_B
      55.23% cov
    • Alignment Length
      132 aa
    • CIGAR string
      23M2N3MN5MN2M2NMN14MN12MN19MN14MN4MN5MN9MN3MN3M mismatches: 15 - insertions: 0 - deletions: 0
  • Mus musculus domesticus

    Mus musculus domesticus

    • Public DB hit
      GI:576600
      AAA53292
    • Hit length
      148 aa
    • E Value
      6.32E-61
    • BLAST Score
      237.7 bits
    • Similarity
      93.94%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 8
      100% cov
      AAA53292
      89.19% cov
    • Alignment Length
      132 aa
    • CIGAR string
      23M2N3MN5MN2M2NMN11MN2MNMN10MN19MN14MN4MN5MN5MN3MN3MN3M mismatches: 18 - insertions: 0 - deletions: 0
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:125834
      P06314
      1 of 6 hits reported for Homo sapiens.
    • Hit length
      134 aa
    • E Value
      4.65E-57
    • BLAST Score
      224.9 bits
    • Similarity
      89.47%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 8
      100% cov
      P06314
      99.25% cov
    • Alignment Length
      133 aa
  • Mus sp.

    Mus sp.

    • Public DB hit
      GI:30387872
      AAP32236
    • Hit length
      137 aa
    • E Value
      1.17E-56
    • BLAST Score
      223.4 bits
    • Similarity
      90.98%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 8
      100% cov
      AAP32236
      97.08% cov
    • Alignment Length
      133 aa
  • Rattus sp.

    Rattus sp.

    • Public DB hit
      GI:1326410
      AAB35891
    • Hit length
      134 aa
    • E Value
      3.59E-56
    • BLAST Score
      221.9 bits
    • Similarity
      89.39%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 8
      100% cov
      AAB35891
      98.51% cov
    • Alignment Length
      132 aa
Occurrence
18 times in PatSeqDB
Tools
SEQ ID NO
9
Length
15
Sequence Type
nucleotide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
17 times in PatSeqDB
Tools
SEQ ID NO
10
Length
5
Sequence Type
peptide
Locations
Detailed Description
Declared organism
Artificial
Determined organism
Occurrence
37 times in PatSeqDB
Tools

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