Methods Of Treating Seizure Disorders


Seizure disorders are treated by Ras inhibitors. In an embodiment, the Ras inhibitor includes a farnesyl transferase inhibitor. In another embodiment, the farnesyl transferase inhibitor includes a 3-hydroxy-3-methylglutaryl-Coenzyme A reductase inhibitor. In another embodiment, the 3-hydroxy-3-methylglutaryl- Coenzyme A reductase inhibitor is not a Ras inhibitor. Subjects having fragile X syndrome, autism, Angelman syndrome, Costello syndrome, cardio facio cutaneous syndrome, neurofibromatosis type I, Noonan syndrome and Coffm-Lowry syndrome that have seizure disorders can be treated.

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Document History
  • Publication: Apr 26, 2012
  • Application: Oct 20, 2011
    WO US 2011/0057099 W
  • Priority: Oct 21, 2010
    US US 40544610 P

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