Identification Of Micrornas (mirnas) In Fecal Samples As Biomarkers For Gastroenterological Cancers

  • Published: Jun 1, 2011
  • Earliest Priority: Oct 09 2009
  • Family: 6
  • Cited Works: 0
  • Cited by: 1
  • Cites: 0
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Abstract

A simple, rapid, inexpensive, and promising commercial biomarker assay method for multiple diseases is described herein. The present invention detects miRNA-based biomarkers in human stool specimens. The method of the present invention amplifies miRNA directly from stool specimens without any prior miRNA extraction. Differential expression of specific microRNAs in stool of colorectal cancer CRC and adenoma patients suggest fecal microRNAs as a novel potential biomarker for colorectal neoplasia detection. The method of the present invention has diagnostic, prognostic, and therapeutic relevance for gastroenterological cancers/colorectal cancer and as well as further acquired or hereditary GI diseases.


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Document History
  • Publication: Jun 1, 2011
  • Application: Oct 8, 2010
    TW TW 99134468 A
  • Priority: Jan 11, 2010
    US US 29403010 P
  • Priority: Oct 9, 2009
    US US 25038809 P

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