Patents
WO 2011/154485 A1

Treating Cancer By Modulating Mammalian Sterile 20-like Kinase 3

  • Published: Dec 15, 2011
  • Earliest Priority: Jun 10 2010
  • Family: 3
  • Cited Works: 136
  • Cited by: 0
  • Cites: 97
  • Sequences: 2
  • Additional Info: Cited Works Full text
Patent Application
WO 2011/154485 A1
038-657-676-659-530
Data obtained from: EPO Sequence Listings EMBL-EBI Pat WIPO-PCT
2 sequences found in this patent (in total)

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Download sequences in fasta format: 2 peptides

Displaying 2 sequences

SEQ ID NO
Length
Sequence Type
Locations
Declared organism
Determined organism
Occurrence
Tools
SEQ ID NO
1
Length
443
Sequence Type
peptide
Locations
Fulltext
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:20070158
      NP_003567
      1 of 6 hits reported for Homo sapiens.
    • Hit length
      443 aa
    • E Value
      0E0
    • BLAST Score
      911.4 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      NP_003567
      100% cov
    • Alignment Length
      443 aa
    • CIGAR string
      443M mismatches: 0 - insertions: 0 - deletions: 0
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:114650410
      XP_001144072
    • Hit length
      443 aa
    • E Value
      0E0
    • BLAST Score
      909.4 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_001144072
      100% cov
    • Alignment Length
      443 aa
    • CIGAR string
      12MN430M mismatches: 1 - insertions: 0 - deletions: 0
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:109121160
      XP_001091015
      1 of 2 hits reported for Macaca mulatta.
    • Hit length
      443 aa
    • E Value
      0E0
    • BLAST Score
      907.5 bits
    • Similarity
      99.77%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_001091015
      100% cov
    • Alignment Length
      443 aa
    • CIGAR string
      17MN390MN34M mismatches: 2 - insertions: 0 - deletions: 0
  • Nomascus leucogenys

    Nomascus leucogenys

    • Public DB hit
      GI:332260360
      XP_003279256
    • Hit length
      431 aa
    • E Value
      0E0
    • BLAST Score
      857.4 bits
    • Similarity
      99.52%
    • Coverage
      94.81%
    • Alignment (schematic)

      SEQ ID NO 1
      94.81% cov
      XP_003279256
      97.45% cov
    • Alignment Length
      420 aa
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:33304141
      AAQ02578
      1 of 2 hits reported for synthetic construct.
    • Hit length
      432 aa
    • E Value
      0E0
    • BLAST Score
      855.5 bits
    • Similarity
      99.52%
    • Coverage
      94.81%
    • Alignment (schematic)

      SEQ ID NO 1
      94.81% cov
      AAQ02578
      97.22% cov
    • Alignment Length
      420 aa
  • Ailuropoda melanoleuca

    Ailuropoda melanoleuca

    • Public DB hit
      GI:301758120
      XP_002914907
    • Hit length
      445 aa
    • E Value
      0E0
    • BLAST Score
      845.9 bits
    • Similarity
      97.08%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 1
      100% cov
      XP_002914907
      100% cov
    • Alignment Length
      445 aa
  • Oryctolagus cuniculus

    Oryctolagus cuniculus

    • Public DB hit
      GI:291393172
      XP_002712988
    • Hit length
      484 aa
    • E Value
      0E0
    • BLAST Score
      829.3 bits
    • Similarity
      99.09%
    • Coverage
      99.32%
    • Alignment (schematic)

      SEQ ID NO 1
      99.32% cov
      XP_002712988
      90.91% cov
    • Alignment Length
      440 aa
  • Bos taurus

    Bos taurus

    • Public DB hit
      GI:255003690
      NP_001093420
    • Hit length
      433 aa
    • E Value
      0E0
    • BLAST Score
      795.4 bits
    • Similarity
      97.63%
    • Coverage
      94.81%
    • Alignment (schematic)

      SEQ ID NO 1
      94.81% cov
      NP_001093420
      97.46% cov
    • Alignment Length
      422 aa
  • Sus scrofa

    Sus scrofa

    • Public DB hit
      GI:335297056
      XP_003357929
    • Hit length
      578 aa
    • E Value
      0E0
    • BLAST Score
      793.5 bits
    • Similarity
      97.86%
    • Coverage
      94.36%
    • Alignment (schematic)

      SEQ ID NO 1
      94.36% cov
      XP_003357929
      72.66% cov
    • Alignment Length
      420 aa
Occurrence
80 times in PatSeqDB
Tools
SEQ ID NO
2
Length
431
Sequence Type
peptide
Locations
Fulltext
Declared organism
Homo sapiens
Determined organism
  • Homo sapiens

    Homo sapiens

    • Public DB hit
      GI:110349738
      NP_001027467
      1 of 6 hits reported for Homo sapiens.
    • Hit length
      431 aa
    • E Value
      0E0
    • BLAST Score
      887.1 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_001027467
      100% cov
    • Alignment Length
      431 aa
    • CIGAR string
      431M mismatches: 0 - insertions: 0 - deletions: 0
  • Macaca mulatta

    Macaca mulatta

    • Public DB hit
      GI:109121156
      XP_001091132
      1 of 2 hits reported for Macaca mulatta.
    • Hit length
      431 aa
    • E Value
      0E0
    • BLAST Score
      885.6 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      XP_001091132
      100% cov
    • Alignment Length
      431 aa
  • synthetic construct

    synthetic construct

    • Public DB hit
      GI:33304141
      AAQ02578
      1 of 2 hits reported for synthetic construct.
    • Hit length
      432 aa
    • E Value
      0E0
    • BLAST Score
      884.8 bits
    • Similarity
      100%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      AAQ02578
      99.77% cov
    • Alignment Length
      431 aa
  • Nomascus leucogenys

    Nomascus leucogenys

    • Public DB hit
      GI:332260360
      XP_003279256
    • Hit length
      431 aa
    • E Value
      0E0
    • BLAST Score
      884 bits
    • Similarity
      99.77%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      XP_003279256
      100% cov
    • Alignment Length
      431 aa
  • Pan troglodytes

    Pan troglodytes

    • Public DB hit
      GI:114650410
      XP_001144072
    • Hit length
      443 aa
    • E Value
      0E0
    • BLAST Score
      858.2 bits
    • Similarity
      97.93%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      XP_001144072
      97.97% cov
    • Alignment Length
      434 aa
  • Bos taurus

    Bos taurus

    • Public DB hit
      GI:255003690
      NP_001093420
    • Hit length
      433 aa
    • E Value
      0E0
    • BLAST Score
      824.3 bits
    • Similarity
      98.15%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_001093420
      100% cov
    • Alignment Length
      433 aa
  • Mus musculus

    Mus musculus

    • Public DB hit
      GI:21703922
      NP_663440
      1 of 2 hits reported for Mus musculus.
    • Hit length
      431 aa
    • E Value
      0E0
    • BLAST Score
      820.5 bits
    • Similarity
      98.84%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_663440
      100% cov
    • Alignment Length
      431 aa
  • Rattus norvegicus

    Rattus norvegicus

    • Public DB hit
      GI:188595689
      NP_001120966
    • Hit length
      431 aa
    • E Value
      0E0
    • BLAST Score
      815.5 bits
    • Similarity
      98.38%
    • Coverage
      100%
    • Alignment (schematic)

      SEQ ID NO 2
      100% cov
      NP_001120966
      100% cov
    • Alignment Length
      431 aa
Occurrence
59 times in PatSeqDB
Tools

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