{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"035-922-458-384-79X","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"035-922-458-384-79X"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":6804,"type":"PATENT","title":"Univ Sydney Patent Portfolio","description":"Searched ' Univ Sydney ' for patent collection. Added owners (US), expanded by simply family and date range set as 01/Jan/2000 - 01/ Apr/ 2015\n","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":47811,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[],"sharedType":"PUBLISHED","hasLinkedSavedQueries":false,"savedQueries":[],"created":"2015-05-04T02:51:05Z","updated":"2015-05-04T04:00:52Z","lastEventDate":"2015-05-04T04:00:52Z"},{"id":11720,"type":"PATENT","title":"University of Iowa - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3930,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8373,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: uni* iowa
Select more for logical variants.
Add to collection.
Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 3686
Search Applicants and Owners separately: uni* iowa
Select more for logical variants.
Add to collection.
Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 3686
(a) rs2274700 with a GCG codon encoding alanine at position 473; or
(b) rs1061147 with a GCA codon encoding alanine at position 307."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3 comprising screening for the presence or absence of a haplotype in the Complement Factor H (CFH) gene, wherein the haplotype comprises rs1061170 with a nucleotide encoding histidine at position 402."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 3, 4 or 5 comprising detecting the identity of the base at said variant sequence in a biological sample from the subject."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 6 wherein the biological sample is a blood sample."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein the step of screening for the presence or absence of a haplotype consists of screening for the presence or absence of one variant polymorphism and said one variant polymorphism is a single nucleotide polymorphism (SNP) at rs2274700 or rs1061147."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 6 wherein the detecting comprises (i) combining a nucleic acid sample from the subject with one or more polynucleotide probes capable of hybridizing selectively to a CFH gene allele and (ii) detecting the presence or absence of hybridization."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 9 wherein the probes are oligonucleotides capable of priming polynucleotide synthesis in an amplification reaction."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The method of any of claims 1 to 10 comprising screening for specific subtypes of AMD."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 11 wherein the subtype is early AMD, geographic atrophy, or exudative AMD (CNV)."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein the haplotype is in the Complement Factor H Related 5 gene."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 13 wherein said screening comprises detecting the presence or absence of a variant sequence at any one or more of rs9427661, rs9427662 and rs120977550."],"number":14,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}