Methods And Systems For Identifying Disease-induced Mutations


The invention includes methods and systems for identifying diseased-induced mutations by producing multi-dimensional reference sequence constructs that account for variations between individuals, different diseases, and different stages of those diseases. Once constructed, these reference sequence constructs can be used to align sequence reads corresponding to genetic samples from patients suspected of having a disease, or who have had the disease and are in suspected remission. The reference sequence constructs also provide insight to the genetic progression of the disease.

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Document History
  • Publication: Aug 21, 2018
  • Application: Oct 17, 2014
    US US 201414517451 A
  • Priority: Oct 17, 2014
    US US 201414517451 A
  • Priority: Oct 18, 2013
    US US 201361892670 P

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